Spyros Yarmenitis - Academia.edu (original) (raw)

Papers by Spyros Yarmenitis

Research paper thumbnail of Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions

European Radiology, 2007

The purpose of this study was to measure apparent diffusion coefficient values of normal liver pa... more The purpose of this study was to measure apparent diffusion coefficient values of normal liver parenchyma and focal liver lesions utilizing a respiratory gated diffusion sequence with multiple b-values and to investigate whether apparent diffusion coefficient (ADC) measurements may be utilized to characterize and differentiate between malignant and benign focal hepatic lesions. Thirty-eight consecutive patients underwent MRI of the liver including diffusion-weighted imaging (DWI). A single-shot echo planar imaging sequence was applied in coronal orientation with multiple b-values (0, 50, 500, 1,000 s/mm2) and respiratory gating. ADC values were recorded on corresponding maps utilizing region of interest measurements in patients with benign (group A), malignant (group B) focal lesions and liver parenchyma (group C). Statistical analysis was applied to check whether differences in mean ADC values were significant (p<0.05). No focal lesions were detected in 11 patients, with a mean ADC value (CI 95%) of liver parenchyma 1.25x10(-3) mm2/s (1.21x10(-3) mm2/s-1.29x10(-3) mm2/s). Differences in mean ADC of liver parenchyma between group A and B were not significant (p=0.054, 1.30x10(-3) mm2/s and 1.31x10(-3) mm2/s, respectively). Mean ADC value (95% CI) of 22 benign lesions found in 18 patients was 2.55x10(-3) mm2/s (2.35x10(-3) mm2/s-2.74x10(-3) mm2/s), while the mean ADC value (95% CI) of 16 malignant lesions recorded in 9 patients was 1.04x10(-3) mm2/s (0.9x10(-3) mm2/s-1.17x10(-3) mm2/s). The difference between mean ADC values of benign and malignant focal lesions was statistically significant (p<0.0001). Respiratory gated diffusion-weighted imaging in the liver is technically feasible. Apparent diffusion coefficient measurements can be useful in differentiating malignant from benign focal liver lesions.

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Research paper thumbnail of Degenerative Disk Disease of the Cervical Spine: Spectrum of Imaging Findings

Poster: "ESSR 2014 / P-0118 / Degenerative Disk Disease of the Cervical Spine: Spectrum of I... more Poster: "ESSR 2014 / P-0118 / Degenerative Disk Disease of the Cervical Spine: Spectrum of Imaging Findings" by: "M. Tzalonikou1, S. Yarmenitis2, F. Laspas2, G. Delimpasis1, J. Andreou2; 1Athens/GR, 2Marousi/GR"

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Research paper thumbnail of Conventional Radiology of Bone and Soft Tissue Tumors

Imaging in Clinical Oncology, 2013

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Research paper thumbnail of Imaging Findings in Gastrointestinal Cancer: Esophagus, Stomach

Imaging in Clinical Oncology, 2013

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Research paper thumbnail of Ultrasound of the gallbladder and the biliary tree

European Radiology, Mar 1, 2002

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Research paper thumbnail of Elastography: Can It Improve Prostate Biopsy Results?

The Prostate Cancer Dilemma, 2016

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Research paper thumbnail of MP48-09 Results of Transperineal Mapping Biopsy of the Prostate

The Journal of Urology, 2015

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Research paper thumbnail of Ultrasonography in differentiation between chronic viral hepatitis and compensated early stage cirrhosis

World Journal of Gastroenterology, 2008

To assess the value of gray scale (GS) and colour Doppler ultrasonography (CDU) in differentiatin... more To assess the value of gray scale (GS) and colour Doppler ultrasonography (CDU) in differentiating the progression of chronic viral hepatitis (CVH) and compensated liver cirrhosis (CIR). Seventy-two patients and 32 normal individuals who were used as controls were studied. Forty-four patients suffered from CVH and 28 from CIR. All patients were underwent to liver biopsy. Multiple qualitative and quantitative variables were studied in liver, portal vein (PV), hepatic artery (HA) and spleen with GS and CDU. On the basis of the obtained CDU data, several known indexes were calculated. In addition, alternative indices [PV diameter (D)/time average mean velocity (VTAM), HA/PV VTAM ratio] were calculated and studied. ROC analysis showed that PV congestion index, PV D/VTAM and HA/PV VTAM indices had the best sensitivity and specificity in discriminating CVH from CIR. Stepwise discriminant analysis showed that 88.9% of the originally grouped cases could be correctly classified by the three qualitative and four quantitative variables selected as statistically significant predictors. Among the CVH patients who underwent to biopsy, statistically significant changes were found in those at fibrosis stage 5 compared to fibrosis stages 1-4. Simple GS and CDU parameters discriminate CVH from CIR. The alternative Doppler indexes can accurately differentiate chronic virus hepatitis from cirrhosis. These indexes can be used in monitoring chronic virus hepatitis and avoiding unnecessary biopsies.

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Research paper thumbnail of Maternal smoking during pregnancy improves the anatomy of the hip joint in the female neonate

Journal of Maternal-Fetal and Neonatal Medicine, 2003

Because the greater frequency of developmental dysplasia of the hip in the female could have an e... more Because the greater frequency of developmental dysplasia of the hip in the female could have an endocrine etiology, and because maternal smoking in pregnancy causes fetal endocrine disequilibrium, we investigated the anatomy of the hip in neonates of smoking and non-smoking mothers. Clinical and sonographic examination was performed on 2066 hips of 521 male and 512 female neonates. In 48 male and 53 female neonates, the mothers smoked during pregnancy. The mean +/- SD alpha angle in the male neonates of the non-smoking mothers was 62.3 degrees +/- 5.1 degrees and of the smoking mothers 62.1 degrees +/- 4.9 degrees (p = 0.7). In the female neonates of the non-smoking and the smoking mothers, it was 60.7 degrees +/- 5.3 degrees and 61.9 degrees +/- 4.8 degrees, respectively (p = 0.02). The difference between the male and the female neonates of the non-smoking mothers was significant (p < 0.000001), but there was no significant difference between the female neonates of the smoking mothers and the male neonates (p = 0.5). Among the female neonates whose mothers were non-smokers, the number of those with hip type IIa or worse was significantly greater than among the female neonates whose mothers were smokers. The clinical findings were in agreement with the sonographic findings. Maternal smoking during pregnancy reduces the frequency of sonographic and possibly clinically detected hip dysplasia in female but not in male neonates. Nonetheless, because smoking causes numerous adverse effects on the fetus and child, it is contraindicated during pregnancy.

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Research paper thumbnail of Ultrasound of the gallbladder and the biliary tree

European Radiology, 2002

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Research paper thumbnail of Preoperative Imaging Staging of Rectal Cancer

Digestive Diseases, Feb 1, 2007

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Research paper thumbnail of Comparison between two-point and four-point methods for quantification of apparent diffusion coefficient of normal liver parenchyma and focal lesions. Value of normalization with spleen

European Journal of Radiology, 2010

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Research paper thumbnail of Preoperative Imaging Staging of Rectal Cancer

Digestive Diseases, 2007

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Research paper thumbnail of Percutaneous ethanol injection therapy: a surgery-sparing treatment for primary hyperparathyroidism

Clinical Endocrinology, 2008

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Research paper thumbnail of Performance of computed tomographic urography in diagnosis of upper urinary tract urothelial carcinoma, in patients presenting with hematuria: Systematic review and meta-analysis

European Journal of Radiology, Jan 2, 2010

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Research paper thumbnail of Atypical calcified coarctation of the aorta

Rofo Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, Jul 1, 1987

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Research paper thumbnail of Gall-bladder contraction induced by intravenous erythromycin administration. Relation to body mass index

Hepato-gastroenterology

To study the action of intravenously administered erythromycin lactobionate on human gallbladder ... more To study the action of intravenously administered erythromycin lactobionate on human gallbladder volume, as a possible preventive method against gallbladder stone formation, in high risk patients such as those in sepsis, long standing fasting periods or those receiving prolonged total parenteral nutrition or octreotide. Twenty-two volunteers randomized to receive intravenously either erythromycin lactobionate 7 mg per kg (study group) or normal saline (controls). We measured ultrasonographically the gallbladder volume before and at 5, 15, 35, 55, 90, 120 and 180 min after the infusion. Erythromycin induced a biphasic gallbladder contraction, with maximum contractility at 15 min (10.2%) and between 120 and 180 min (22.6%), compared to normal saline controls. Late contractility was correlated to body mass index (BMI). Erythromycin activity on gallbladder contraction is proved. Its biphasic action needs further investigation to find the involved mechanism(s). Long term administration is also necessary to test its efficacy in preventing gallbladder dilatation.

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Research paper thumbnail of Can the iPad Be Used in the Diagnosis of Bone Fractures: Preliminary Results

ABSTRACT

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Research paper thumbnail of Imaging patients with renal colic-consider ultrasound first

Insights into imaging, Jan 21, 2015

Renal colic is a common disease in Europe and a common cause of visit to the Emergency Department... more Renal colic is a common disease in Europe and a common cause of visit to the Emergency Department. Clinical diagnosis is usually confirmed by imaging modalities. Unenhanced computed tomography (CT) is considered the best diagnostic test due to its excellent accuracy detecting ureteral stones. However, ultrasound (US) should be considered as the primary imaging technique. It is a reproducible, non-invasive and non-expensive imaging technique, achieving accurate diagnosis in most cases without the need for radiation. Diagnosis is based on the presence of ureteral stones, but indirect findings such as the asymmetry or absence of ureteric jet, an increase of the resistive index or a colour Doppler twinkling artefact may help to suggest the diagnosis when the stone is not identified. • Renal colic diagnosis is usually confirmed by imaging modalities. • Imaging diagnosis of renal colic is based on the detection of ureteral stones. • CT is the most accurate imaging technique to identify ur...

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Research paper thumbnail of The value of scintigraphy and ultrasonography in the preoperative localization of parathyroid glands in patients with primary hyperparathyroidism and concomitant thyroid disease

Hormones (Athens, Greece)

Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative ... more Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative localization procedures in primary hyperparathyroidism. However, when thyroid disease coexists, their diagnostic accuracy is probably abated. 56 patients with primary hyperparathyroidism were prospectively evaluated with parathyroid scintigraphy (with either thallium or technetium-99m agents or both) and 44 of them were also evaluated with ultrasonography. 33 patients (59%) had coexistent thyroid disease. Upon operation, 48 patients were found to have a solitary parathyroid adenoma and were all cured. One patient had a carcinoma and 7 had multiglandular parathyroid disease. Regarding solitary lesions, the sensitivity of parathyroid scintigraphy with Tc-agents was 97% and thallium 78%, while that of ultrasonography was 74%. The false positive rate was 2.6%, 18%, and 22%, respectively. Concomitant thyroid disease had a non-significant effect on the results of parathyroid scintigraphy and u...

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Research paper thumbnail of Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions

European Radiology, 2007

The purpose of this study was to measure apparent diffusion coefficient values of normal liver pa... more The purpose of this study was to measure apparent diffusion coefficient values of normal liver parenchyma and focal liver lesions utilizing a respiratory gated diffusion sequence with multiple b-values and to investigate whether apparent diffusion coefficient (ADC) measurements may be utilized to characterize and differentiate between malignant and benign focal hepatic lesions. Thirty-eight consecutive patients underwent MRI of the liver including diffusion-weighted imaging (DWI). A single-shot echo planar imaging sequence was applied in coronal orientation with multiple b-values (0, 50, 500, 1,000 s/mm2) and respiratory gating. ADC values were recorded on corresponding maps utilizing region of interest measurements in patients with benign (group A), malignant (group B) focal lesions and liver parenchyma (group C). Statistical analysis was applied to check whether differences in mean ADC values were significant (p<0.05). No focal lesions were detected in 11 patients, with a mean ADC value (CI 95%) of liver parenchyma 1.25x10(-3) mm2/s (1.21x10(-3) mm2/s-1.29x10(-3) mm2/s). Differences in mean ADC of liver parenchyma between group A and B were not significant (p=0.054, 1.30x10(-3) mm2/s and 1.31x10(-3) mm2/s, respectively). Mean ADC value (95% CI) of 22 benign lesions found in 18 patients was 2.55x10(-3) mm2/s (2.35x10(-3) mm2/s-2.74x10(-3) mm2/s), while the mean ADC value (95% CI) of 16 malignant lesions recorded in 9 patients was 1.04x10(-3) mm2/s (0.9x10(-3) mm2/s-1.17x10(-3) mm2/s). The difference between mean ADC values of benign and malignant focal lesions was statistically significant (p<0.0001). Respiratory gated diffusion-weighted imaging in the liver is technically feasible. Apparent diffusion coefficient measurements can be useful in differentiating malignant from benign focal liver lesions.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Degenerative Disk Disease of the Cervical Spine: Spectrum of Imaging Findings

Poster: "ESSR 2014 / P-0118 / Degenerative Disk Disease of the Cervical Spine: Spectrum of I... more Poster: "ESSR 2014 / P-0118 / Degenerative Disk Disease of the Cervical Spine: Spectrum of Imaging Findings" by: "M. Tzalonikou1, S. Yarmenitis2, F. Laspas2, G. Delimpasis1, J. Andreou2; 1Athens/GR, 2Marousi/GR"

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Research paper thumbnail of Conventional Radiology of Bone and Soft Tissue Tumors

Imaging in Clinical Oncology, 2013

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Imaging Findings in Gastrointestinal Cancer: Esophagus, Stomach

Imaging in Clinical Oncology, 2013

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Research paper thumbnail of Ultrasound of the gallbladder and the biliary tree

European Radiology, Mar 1, 2002

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Research paper thumbnail of Elastography: Can It Improve Prostate Biopsy Results?

The Prostate Cancer Dilemma, 2016

Bookmarks Related papers MentionsView impact

Research paper thumbnail of MP48-09 Results of Transperineal Mapping Biopsy of the Prostate

The Journal of Urology, 2015

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Research paper thumbnail of Ultrasonography in differentiation between chronic viral hepatitis and compensated early stage cirrhosis

World Journal of Gastroenterology, 2008

To assess the value of gray scale (GS) and colour Doppler ultrasonography (CDU) in differentiatin... more To assess the value of gray scale (GS) and colour Doppler ultrasonography (CDU) in differentiating the progression of chronic viral hepatitis (CVH) and compensated liver cirrhosis (CIR). Seventy-two patients and 32 normal individuals who were used as controls were studied. Forty-four patients suffered from CVH and 28 from CIR. All patients were underwent to liver biopsy. Multiple qualitative and quantitative variables were studied in liver, portal vein (PV), hepatic artery (HA) and spleen with GS and CDU. On the basis of the obtained CDU data, several known indexes were calculated. In addition, alternative indices [PV diameter (D)/time average mean velocity (VTAM), HA/PV VTAM ratio] were calculated and studied. ROC analysis showed that PV congestion index, PV D/VTAM and HA/PV VTAM indices had the best sensitivity and specificity in discriminating CVH from CIR. Stepwise discriminant analysis showed that 88.9% of the originally grouped cases could be correctly classified by the three qualitative and four quantitative variables selected as statistically significant predictors. Among the CVH patients who underwent to biopsy, statistically significant changes were found in those at fibrosis stage 5 compared to fibrosis stages 1-4. Simple GS and CDU parameters discriminate CVH from CIR. The alternative Doppler indexes can accurately differentiate chronic virus hepatitis from cirrhosis. These indexes can be used in monitoring chronic virus hepatitis and avoiding unnecessary biopsies.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Maternal smoking during pregnancy improves the anatomy of the hip joint in the female neonate

Journal of Maternal-Fetal and Neonatal Medicine, 2003

Because the greater frequency of developmental dysplasia of the hip in the female could have an e... more Because the greater frequency of developmental dysplasia of the hip in the female could have an endocrine etiology, and because maternal smoking in pregnancy causes fetal endocrine disequilibrium, we investigated the anatomy of the hip in neonates of smoking and non-smoking mothers. Clinical and sonographic examination was performed on 2066 hips of 521 male and 512 female neonates. In 48 male and 53 female neonates, the mothers smoked during pregnancy. The mean +/- SD alpha angle in the male neonates of the non-smoking mothers was 62.3 degrees +/- 5.1 degrees and of the smoking mothers 62.1 degrees +/- 4.9 degrees (p = 0.7). In the female neonates of the non-smoking and the smoking mothers, it was 60.7 degrees +/- 5.3 degrees and 61.9 degrees +/- 4.8 degrees, respectively (p = 0.02). The difference between the male and the female neonates of the non-smoking mothers was significant (p < 0.000001), but there was no significant difference between the female neonates of the smoking mothers and the male neonates (p = 0.5). Among the female neonates whose mothers were non-smokers, the number of those with hip type IIa or worse was significantly greater than among the female neonates whose mothers were smokers. The clinical findings were in agreement with the sonographic findings. Maternal smoking during pregnancy reduces the frequency of sonographic and possibly clinically detected hip dysplasia in female but not in male neonates. Nonetheless, because smoking causes numerous adverse effects on the fetus and child, it is contraindicated during pregnancy.

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Research paper thumbnail of Ultrasound of the gallbladder and the biliary tree

European Radiology, 2002

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Research paper thumbnail of Preoperative Imaging Staging of Rectal Cancer

Digestive Diseases, Feb 1, 2007

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Research paper thumbnail of Comparison between two-point and four-point methods for quantification of apparent diffusion coefficient of normal liver parenchyma and focal lesions. Value of normalization with spleen

European Journal of Radiology, 2010

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Preoperative Imaging Staging of Rectal Cancer

Digestive Diseases, 2007

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Percutaneous ethanol injection therapy: a surgery-sparing treatment for primary hyperparathyroidism

Clinical Endocrinology, 2008

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Performance of computed tomographic urography in diagnosis of upper urinary tract urothelial carcinoma, in patients presenting with hematuria: Systematic review and meta-analysis

European Journal of Radiology, Jan 2, 2010

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Atypical calcified coarctation of the aorta

Rofo Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, Jul 1, 1987

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Gall-bladder contraction induced by intravenous erythromycin administration. Relation to body mass index

Hepato-gastroenterology

To study the action of intravenously administered erythromycin lactobionate on human gallbladder ... more To study the action of intravenously administered erythromycin lactobionate on human gallbladder volume, as a possible preventive method against gallbladder stone formation, in high risk patients such as those in sepsis, long standing fasting periods or those receiving prolonged total parenteral nutrition or octreotide. Twenty-two volunteers randomized to receive intravenously either erythromycin lactobionate 7 mg per kg (study group) or normal saline (controls). We measured ultrasonographically the gallbladder volume before and at 5, 15, 35, 55, 90, 120 and 180 min after the infusion. Erythromycin induced a biphasic gallbladder contraction, with maximum contractility at 15 min (10.2%) and between 120 and 180 min (22.6%), compared to normal saline controls. Late contractility was correlated to body mass index (BMI). Erythromycin activity on gallbladder contraction is proved. Its biphasic action needs further investigation to find the involved mechanism(s). Long term administration is also necessary to test its efficacy in preventing gallbladder dilatation.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Can the iPad Be Used in the Diagnosis of Bone Fractures: Preliminary Results

ABSTRACT

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Imaging patients with renal colic-consider ultrasound first

Insights into imaging, Jan 21, 2015

Renal colic is a common disease in Europe and a common cause of visit to the Emergency Department... more Renal colic is a common disease in Europe and a common cause of visit to the Emergency Department. Clinical diagnosis is usually confirmed by imaging modalities. Unenhanced computed tomography (CT) is considered the best diagnostic test due to its excellent accuracy detecting ureteral stones. However, ultrasound (US) should be considered as the primary imaging technique. It is a reproducible, non-invasive and non-expensive imaging technique, achieving accurate diagnosis in most cases without the need for radiation. Diagnosis is based on the presence of ureteral stones, but indirect findings such as the asymmetry or absence of ureteric jet, an increase of the resistive index or a colour Doppler twinkling artefact may help to suggest the diagnosis when the stone is not identified. • Renal colic diagnosis is usually confirmed by imaging modalities. • Imaging diagnosis of renal colic is based on the detection of ureteral stones. • CT is the most accurate imaging technique to identify ur...

Bookmarks Related papers MentionsView impact

Research paper thumbnail of The value of scintigraphy and ultrasonography in the preoperative localization of parathyroid glands in patients with primary hyperparathyroidism and concomitant thyroid disease

Hormones (Athens, Greece)

Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative ... more Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative localization procedures in primary hyperparathyroidism. However, when thyroid disease coexists, their diagnostic accuracy is probably abated. 56 patients with primary hyperparathyroidism were prospectively evaluated with parathyroid scintigraphy (with either thallium or technetium-99m agents or both) and 44 of them were also evaluated with ultrasonography. 33 patients (59%) had coexistent thyroid disease. Upon operation, 48 patients were found to have a solitary parathyroid adenoma and were all cured. One patient had a carcinoma and 7 had multiglandular parathyroid disease. Regarding solitary lesions, the sensitivity of parathyroid scintigraphy with Tc-agents was 97% and thallium 78%, while that of ultrasonography was 74%. The false positive rate was 2.6%, 18%, and 22%, respectively. Concomitant thyroid disease had a non-significant effect on the results of parathyroid scintigraphy and u...

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