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Update of the EMQN/ACGS best practice guidelines for molecular analysis of Prader-Willi and Angelman syndromes, 2019
This article is an update of the best practice guidelines for the molecular analysis of Prader-Wi... more This article is an update of the best practice guidelines for the molecular analysis of Prader-Willi and Angelman syndromes published in 2010 in BMC Medical Genetics [1]. The update takes into account developments in terms of techniques, differential diagnoses and (especially) reporting standards. It highlights the advantages and disadvantages of each method and moreover, is meant to facilitate the interpretation of the obtained results-leading to improved standardised reports.
Journal of Drug Delivery and Therapeutics, 2013
The aim of the research work was to isolate a novel bio material from the seeds of Buchanania Lan... more The aim of the research work was to isolate a novel bio material from the seeds of Buchanania Lanzan and to evaluate its bio stabilizing ability by various formulating various zidovudine micro emulsions using sunflower oil as oil phase and bio material as bio emulsifier. The bio material was isolated from the seeds of Buchanania Lanzan by simplified economical method. Three different zidovudine micro emulsions were formulated using the bio emulsifier in different concentrations. The formulated micro emulsions were subjected to various evaluation parameters like globule size, ph effect of centrifugation , viscosity, surface tension and invitro drug release. The formulated micro emulsions exhibit uniform globule size, promising stability against centrifugation effect in comparison to standard emulsion. The drug release studies from the formulated micro emulsions exhibited a promising transparency, stability, uniform globule size and shape, surface tension for a period of 24 hrs. Finally the conclusion was drawn that the isolated bio emulsifier acts as novel emulsifier for formulating various drug loaded micro emulsions.
Update of the EMQN/ACGS best practice guidelines for molecular analysis of Prader-Willi and Angelman syndromes, 2019
This article is an update of the best practice guidelines for the molecular analysis of Prader-Wi... more This article is an update of the best practice guidelines for the molecular analysis of Prader-Willi and Angelman syndromes published in 2010 in BMC Medical Genetics [1]. The update takes into account developments in terms of techniques, differential diagnoses and (especially) reporting standards. It highlights the advantages and disadvantages of each method and moreover, is meant to facilitate the interpretation of the obtained results-leading to improved standardised reports.
Journal of Drug Delivery and Therapeutics, 2013
The aim of the research work was to isolate a novel bio material from the seeds of Buchanania Lan... more The aim of the research work was to isolate a novel bio material from the seeds of Buchanania Lanzan and to evaluate its bio stabilizing ability by various formulating various zidovudine micro emulsions using sunflower oil as oil phase and bio material as bio emulsifier. The bio material was isolated from the seeds of Buchanania Lanzan by simplified economical method. Three different zidovudine micro emulsions were formulated using the bio emulsifier in different concentrations. The formulated micro emulsions were subjected to various evaluation parameters like globule size, ph effect of centrifugation , viscosity, surface tension and invitro drug release. The formulated micro emulsions exhibit uniform globule size, promising stability against centrifugation effect in comparison to standard emulsion. The drug release studies from the formulated micro emulsions exhibited a promising transparency, stability, uniform globule size and shape, surface tension for a period of 24 hrs. Finally the conclusion was drawn that the isolated bio emulsifier acts as novel emulsifier for formulating various drug loaded micro emulsions.