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Papers by Stephen Schendel
Annals of Plastic Surgery, Jul 1, 1987
Annals of Plastic Surgery, 1990
Journal of Oral and Maxillofacial Surgery, Feb 1, 1984
International Journal of Oral and Maxillofacial Surgery, Dec 1, 2019
Beckwith-Wiedemann syndrome is a condition that affects many parts of the body. It is classified ... more Beckwith-Wiedemann syndrome is a condition that affects many parts of the body. It is classified as an overgrowth syndrome, which means that affected infants are considerably larger than normal (macrosomia) and tend to be taller than their peers during childhood. Growth begins to slow by about age 8, and adults with this condition are not unusually tall. In some children with Beckwith-Wiedemann syndrome, specific parts of the body on one side or the other may grow abnormally large, leading to an asymmetric or uneven appearance. This unusual growth pattern, which is known as hemihyperplasia, usually becomes less apparent over time.
Annals of Plastic Surgery, Jun 1, 1987
Oral and Maxillofacial Surgery Clinics of North America, Feb 1, 1996
The Year book of perinatal/neonatal medicine, 2006
To avoid tracheostomy in 11 neonates with severe Pierre Robin sequence, we used a technique of pr... more To avoid tracheostomy in 11 neonates with severe Pierre Robin sequence, we used a technique of progressive elongation of the mandible (distraction osteogenesis) to correct tongue ptosis, increase pharyngeal airway, and correct micrognathia. All 11 patients were extubated within 3 to 6 days after beginning distraction. At 1 month 54.5% were oral feeders and at 1 year, 100%. Sleep studies were obtained on 7 patients and were normal 1 week to 1 month after operation. Growth was observed to be above the 50th percentile in all patients with no comorbidities. A 5-year clinical follow-up showed the operated mandible to maintain a normal shape and produce an undisturbed tooth eruption sequence. We conclude that distraction osteogenesis to increase the length of the short mandible is an effective alternative to tracheostomy in carefully selected patients.
Plastic and Reconstructive Surgery, Aug 1, 1995
Journal of Oral and Maxillofacial Surgery, Aug 1, 1991
Annals of Plastic Surgery, Sep 1, 1991
Annals of Plastic Surgery, Jun 1, 1990
Journal of Oral and Maxillofacial Surgery, Sep 1, 2012
Aesthetic Surgery Journal, May 16, 2017
Background: Autologous collagen is an ideal soft tissue filler and may serve as a matrix for stem... more Background: Autologous collagen is an ideal soft tissue filler and may serve as a matrix for stem cell implantation and growth. Procurement of autologous collagen has been limited, though, secondary to a sufficient source. Liposuction is a widely performed and could be a source of autologous collagen. Objectives: The amount of collagen and its composition in liposuctioned fat remains unknown. The purpose of this research was to characterize an adipose-derived tissue-based product created using ultrasonic cavitation and cryo-grinding. This study evaluated the cellular and protein composition of the final product. Methods: Fat was obtained from individuals undergoing routine liposuction and was processed by a 2 step process to obtain only the connective tissue. The tissue was then evaluated by scanning electronic microscope, Western blot analysis, and flow cytometry. Results: Liposuctioned fat was obtained from 10 individuals with an average of 298 mL per subject. After processing an average of 1 mL of collagen matrix was obtained from each 100 mL of fat. Significant viable cell markers were present in descending order for adipocytes > CD90+ > CD105+ > CD45+ > CD19+ > CD144+ > CD34+. Western blot analysis showed collagen type II, III, IV, and other proteins. Scanning electronic microscope study showed a regular pattern of cross-linked, helical collagen. Additionally, vital staing demonstrated that the cells were still viable after processing. Conclusions: Collagen and cells can be easily obtained from liposuctioned fat by ultrasonic separation without alteration of the overall cellular composition of the tissue. Implantation results in new collagen and cellular growth. Collagen matrix with viable cells for autologous use can be obtained from liposuctioned fat and may provide long term results.
Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology, Oct 1, 2016
Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale, Feb 1, 2015
Introduction. We present and assess a surgical technique for maxillary auto-bone grafting concomi... more Introduction. We present and assess a surgical technique for maxillary auto-bone grafting concomitantly with Le Fort I osteotomy. The graft has 2 main objectives: to fill in the space between the 2 advanced segments of the maxilla to help bone consolidation, and to increase the volume of the malar, para-nasal spaces to improve postoperative esthetic results. Technical note. Bone fragments, removed during the Le Fort I osteotomy, are stored and wrapped in a Surgicel W sheet, then grafted in the space left by the osteotomy, or on the anterior maxilla in the para-nasal area or on the malar bone. One hundred and twenty-three patient records, operated from 2007 to 2012, were collected to assess the post-operative course retrospectively. The post-operative course was uneventful in 93.5% of cases. About 8.4% of patients (7 cases) presented with a persistent post-operative maxillary edema. 1 patient (1.2%) presented with a sinus infection without any determined etiology. The grafts were all osteointegrated at the end of follow-up. Discussion. The technique is simple and quickly performed; it improves bone healing and cosmetic results, without increasing morbidity or surgical time. It is a good alternative to bone grafts from a secondary sample site. It can be applied to all Le Fort I osteotomies.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science, 2004
Successful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindre... more Successful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindred with autosomal recessive transmission for a complete cleft palate phenotype. This case represents the potential application of a new animal model for cleft palate repair. This reproducible congenital defect provides a clinically relevant model to improve research into the human anomaly, as compared with previous iatrogenic or teratogenically induced animal models. This case report presents the basis for new repair techniques and for studying the genetic basis of the cleft palate defect.
Journal of Oral and Maxillofacial Surgery, 2008
bone grafting, orthognathic surgery, and nose lip revisions. Special topics will include the use ... more bone grafting, orthognathic surgery, and nose lip revisions. Special topics will include the use of NAM or nasal alveolar molding, indications and guidelines for maxillary distraction, the use of BMP (bone morphogenic protein) in bone grafting. A new technique for primary lip repair (Fisher repair) will be presented combined with the use of primary nasal reconstruction in both bilateral and unilateral clefts. This presentation will be of benefit to any surgeon who wishes to expand their understanding of treating a child with a cleft deformity. It will emphasize treatment planning of a sequence of surgical procedures beginning with lip repairs and ending with the final stages of nose lip revisions. Both presenters have active cleft surgery practices in the NYC area and are involved in the third world missions. Slides and videos will be used to illustrate the talk.
Annals of Plastic Surgery, Jul 1, 1987
Annals of Plastic Surgery, 1990
Journal of Oral and Maxillofacial Surgery, Feb 1, 1984
International Journal of Oral and Maxillofacial Surgery, Dec 1, 2019
Beckwith-Wiedemann syndrome is a condition that affects many parts of the body. It is classified ... more Beckwith-Wiedemann syndrome is a condition that affects many parts of the body. It is classified as an overgrowth syndrome, which means that affected infants are considerably larger than normal (macrosomia) and tend to be taller than their peers during childhood. Growth begins to slow by about age 8, and adults with this condition are not unusually tall. In some children with Beckwith-Wiedemann syndrome, specific parts of the body on one side or the other may grow abnormally large, leading to an asymmetric or uneven appearance. This unusual growth pattern, which is known as hemihyperplasia, usually becomes less apparent over time.
Annals of Plastic Surgery, Jun 1, 1987
Oral and Maxillofacial Surgery Clinics of North America, Feb 1, 1996
The Year book of perinatal/neonatal medicine, 2006
To avoid tracheostomy in 11 neonates with severe Pierre Robin sequence, we used a technique of pr... more To avoid tracheostomy in 11 neonates with severe Pierre Robin sequence, we used a technique of progressive elongation of the mandible (distraction osteogenesis) to correct tongue ptosis, increase pharyngeal airway, and correct micrognathia. All 11 patients were extubated within 3 to 6 days after beginning distraction. At 1 month 54.5% were oral feeders and at 1 year, 100%. Sleep studies were obtained on 7 patients and were normal 1 week to 1 month after operation. Growth was observed to be above the 50th percentile in all patients with no comorbidities. A 5-year clinical follow-up showed the operated mandible to maintain a normal shape and produce an undisturbed tooth eruption sequence. We conclude that distraction osteogenesis to increase the length of the short mandible is an effective alternative to tracheostomy in carefully selected patients.
Plastic and Reconstructive Surgery, Aug 1, 1995
Journal of Oral and Maxillofacial Surgery, Aug 1, 1991
Annals of Plastic Surgery, Sep 1, 1991
Annals of Plastic Surgery, Jun 1, 1990
Journal of Oral and Maxillofacial Surgery, Sep 1, 2012
Aesthetic Surgery Journal, May 16, 2017
Background: Autologous collagen is an ideal soft tissue filler and may serve as a matrix for stem... more Background: Autologous collagen is an ideal soft tissue filler and may serve as a matrix for stem cell implantation and growth. Procurement of autologous collagen has been limited, though, secondary to a sufficient source. Liposuction is a widely performed and could be a source of autologous collagen. Objectives: The amount of collagen and its composition in liposuctioned fat remains unknown. The purpose of this research was to characterize an adipose-derived tissue-based product created using ultrasonic cavitation and cryo-grinding. This study evaluated the cellular and protein composition of the final product. Methods: Fat was obtained from individuals undergoing routine liposuction and was processed by a 2 step process to obtain only the connective tissue. The tissue was then evaluated by scanning electronic microscope, Western blot analysis, and flow cytometry. Results: Liposuctioned fat was obtained from 10 individuals with an average of 298 mL per subject. After processing an average of 1 mL of collagen matrix was obtained from each 100 mL of fat. Significant viable cell markers were present in descending order for adipocytes > CD90+ > CD105+ > CD45+ > CD19+ > CD144+ > CD34+. Western blot analysis showed collagen type II, III, IV, and other proteins. Scanning electronic microscope study showed a regular pattern of cross-linked, helical collagen. Additionally, vital staing demonstrated that the cells were still viable after processing. Conclusions: Collagen and cells can be easily obtained from liposuctioned fat by ultrasonic separation without alteration of the overall cellular composition of the tissue. Implantation results in new collagen and cellular growth. Collagen matrix with viable cells for autologous use can be obtained from liposuctioned fat and may provide long term results.
Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology, Oct 1, 2016
Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale, Feb 1, 2015
Introduction. We present and assess a surgical technique for maxillary auto-bone grafting concomi... more Introduction. We present and assess a surgical technique for maxillary auto-bone grafting concomitantly with Le Fort I osteotomy. The graft has 2 main objectives: to fill in the space between the 2 advanced segments of the maxilla to help bone consolidation, and to increase the volume of the malar, para-nasal spaces to improve postoperative esthetic results. Technical note. Bone fragments, removed during the Le Fort I osteotomy, are stored and wrapped in a Surgicel W sheet, then grafted in the space left by the osteotomy, or on the anterior maxilla in the para-nasal area or on the malar bone. One hundred and twenty-three patient records, operated from 2007 to 2012, were collected to assess the post-operative course retrospectively. The post-operative course was uneventful in 93.5% of cases. About 8.4% of patients (7 cases) presented with a persistent post-operative maxillary edema. 1 patient (1.2%) presented with a sinus infection without any determined etiology. The grafts were all osteointegrated at the end of follow-up. Discussion. The technique is simple and quickly performed; it improves bone healing and cosmetic results, without increasing morbidity or surgical time. It is a good alternative to bone grafts from a secondary sample site. It can be applied to all Le Fort I osteotomies.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science, 2004
Successful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindre... more Successful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindred with autosomal recessive transmission for a complete cleft palate phenotype. This case represents the potential application of a new animal model for cleft palate repair. This reproducible congenital defect provides a clinically relevant model to improve research into the human anomaly, as compared with previous iatrogenic or teratogenically induced animal models. This case report presents the basis for new repair techniques and for studying the genetic basis of the cleft palate defect.
Journal of Oral and Maxillofacial Surgery, 2008
bone grafting, orthognathic surgery, and nose lip revisions. Special topics will include the use ... more bone grafting, orthognathic surgery, and nose lip revisions. Special topics will include the use of NAM or nasal alveolar molding, indications and guidelines for maxillary distraction, the use of BMP (bone morphogenic protein) in bone grafting. A new technique for primary lip repair (Fisher repair) will be presented combined with the use of primary nasal reconstruction in both bilateral and unilateral clefts. This presentation will be of benefit to any surgeon who wishes to expand their understanding of treating a child with a cleft deformity. It will emphasize treatment planning of a sequence of surgical procedures beginning with lip repairs and ending with the final stages of nose lip revisions. Both presenters have active cleft surgery practices in the NYC area and are involved in the third world missions. Slides and videos will be used to illustrate the talk.