Steve Turner - Academia.edu (original) (raw)
Papers by Steve Turner
A longitudinal study of lung function from 1 month to 18 years of age
APSCOM-97. International Conference on Advances in Power System Control, Operation and Management, 1997
Abstract This paper describes the application of a permissive overreaching transfer trip (POTT) s... more Abstract This paper describes the application of a permissive overreaching transfer trip (POTT) system to protect a double circuit transmission line for which single pole tripping and reclosing was required to ensure power system stability. Application of the advanced relay ...
Frontiers in pediatrics, 2017
Asthma is a common condition, which is associated with atopy and allergic conditions including ha... more Asthma is a common condition, which is associated with atopy and allergic conditions including hay fever, eczema, and food allergies. Asthma and atopy are both complex conditions where genetic and environmental factors are implicated in causation. Interactions between genetic and environmental factors, likely via epigenetic mechanisms, are widely thought to be important in determining the risk for developing asthma and atopy. The nature of the relationship between asthma and atopy is unclear and the answer to the question "does atopy cause asthma?" remains unknown. This review explores the relationship between asthma and atopy from a gene-environment interaction perspective and tackles the question "are similar gene-environment interactions present for asthma and atopy?" The main finding is that gene-environment interactions are described for asthma and atopy in children but these interactions are seldom sought for both asthma and atopy in the same population. In...
Respirology (Carlton, Vic.), 2016
European Respiratory Review, 2015
Management-related issues are an important aspect of monitoring asthma in children in clinical pr... more Management-related issues are an important aspect of monitoring asthma in children in clinical practice. This review summarises the literature on practical aspects of monitoring including adherence to treatment, inhalation technique, ongoing exposure to allergens and irritants, comorbid conditions and side-effects of treatment, as agreed by the European Respiratory Society Task Force on Monitoring Asthma in Childhood.The evidence indicates that it is important to discuss adherence to treatment in a non-confrontational way at every clinic visit, and take into account a patient's illness and medication beliefs. All task force members teach inhalation techniques at least twice when introducing a new inhalation device and then at least annually. Exposure to second-hand tobacco smoke, combustion-derived air pollutants, house dust mites, fungal spores, pollens and pet dander deserve regular attention during follow-up according to most task force members. In addition, allergic rhinitis...
The European respiratory journal, Jan 5, 2015
The goal of asthma treatment is to obtain clinical control and reduce future risks to the patient... more The goal of asthma treatment is to obtain clinical control and reduce future risks to the patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all components of asthma, such as symptoms, lung function, bronchial hyperresponsiveness and inflammation, may exist in various combinations in different individuals, to date there is limited evidence on how to integrate these for optimal monitoring of children with asthma. The aims of this ERS Task Force were to describe the current practise and give an overview of the best available evidence on how to monitor children with asthma. 22 clinical and research experts reviewed the literature. A modified Delphi method and four Task Force meetings were used to reach a consensus. This statement summarises the literature on monitoring children with asthma. Available tools for monitoring children with asthma, such as clinical tools, lung function, bronchial responsiveness and inflammatory markers, are described ...
2014 67th Annual Conference for Protective Relay Engineers, 2014
A numerical generator protection relay provides multiple functions and typically uses algorithms ... more A numerical generator protection relay provides multiple functions and typically uses algorithms that do not work on the same principles as older electromechanical relays. Often relay test personnel still want to use old test methods developed long ago for electromechanical relays. Test results obtained from these old test methods may not be a good indication of whether or not the numerical relay protection functions properly. One such obsolete technique still often used is referred to as a static test. Fault voltage and/or fault current are injected to see if the selected protection function operates at the setpoint and is in tolerance. Many protection functions have dynamic characteristics and/or hidden features that cannot be properly tested using a static test. This paper demonstrates various techniques how to test numerical protection relays such as dynamic tests.
Pediatric Blood & Cancer, 2011
Mental Health Practice, 2007
European Respiratory Journal, 2013
European Respiratory Journal, 2011
European Respiratory Journal, 2012
Archives of Disease in Childhood, 2012
Bronchiolitis is a common lower respiratory tract infection of infancy where management has varie... more Bronchiolitis is a common lower respiratory tract infection of infancy where management has varied considerably in the past. The aim of the present study was to determine whether patient treatment and outcomes changed after introduction of a clinical care pathway. Infants aged up to 6 months admitted to hospital with bronchiolitis were identified as part of an annual audit of bronchiolitis management between winters 2003/2004 and 2009/2010. The primary outcome, duration of stay (DOS), was compared before and after the clinical pathway was introduced before the winter 2005/2006. There were 328 infants identified, mean age 75 days, respiratory syncitial virus was detected in 89%. After the clinical pathway was introduced, the proportion of infants prescribed salbutamol fell from 50% to 8% (p < 0.001) and ipratropium bromide from 38% to 0% (p < 0.001) but the proportion prescribed antibiotics was unchanged. The median DOS was 79 h prior to the clinical pathway and 66 h afterwards (p = 0.010) but there was no difference in days where supplemental oxygen or nasogastric feeding was required. A clinical pathway for the management of acute bronchiolitis can be implemented in the hospital setting and the conservative approach, in particular not prescribing bronchodilators, is not associated with prolonged duration of stay.
Advanced Synthesis & Catalysis, 2012
A new strategy for the synthesis of poly- cyclic imidazole-containing N-heterocycles, based on th... more A new strategy for the synthesis of poly- cyclic imidazole-containing N-heterocycles, based on the two general synthetic ways, namely the Pd(II)- catalyzed intramolecular arylation via CH/CHal and CH/CH coupling reactions, was developed. The method proposed here enables the synthesis of many fused N-heterocycles containing purine, 1-deazapur- ines and benzimidazole structural units.
Acta Crystallographica Section D Biological Crystallography, 1995
Annals of Nigerian Medicine, 2011
The identification of nitric oxide in exhaled breath and its role as a surrogate marker of eosino... more The identification of nitric oxide in exhaled breath and its role as a surrogate marker of eosinophilic inflammation of the airways led to rapid development in the area of its measurement. Standardized measurement techniques have been developed as well as simple, cheap, and reliable equipments. Although a number of factors have been identified as affecting its assay, fractional exhaled nitric oxide (FENO) can reliably be used to distinguish eosinophilic from non-eosinophilic airway inflammation. Unlike the other indirect measures of airway inflammation such as FEV1 reversibility and bronchoprovocative tests, FENO is noninvasive and gives a direct measure of inflammation. There are sufficient data supporting its role in the diagnosis of asthma, monitoring of disease, prediction of relapse, and level of compliance. Measurement of FENO has therefore made the transition from the bench to the bedside. Of recent, there are attempts at devising interpretative strategies for its use in day to day clinical practice.
A longitudinal study of lung function from 1 month to 18 years of age
APSCOM-97. International Conference on Advances in Power System Control, Operation and Management, 1997
Abstract This paper describes the application of a permissive overreaching transfer trip (POTT) s... more Abstract This paper describes the application of a permissive overreaching transfer trip (POTT) system to protect a double circuit transmission line for which single pole tripping and reclosing was required to ensure power system stability. Application of the advanced relay ...
Frontiers in pediatrics, 2017
Asthma is a common condition, which is associated with atopy and allergic conditions including ha... more Asthma is a common condition, which is associated with atopy and allergic conditions including hay fever, eczema, and food allergies. Asthma and atopy are both complex conditions where genetic and environmental factors are implicated in causation. Interactions between genetic and environmental factors, likely via epigenetic mechanisms, are widely thought to be important in determining the risk for developing asthma and atopy. The nature of the relationship between asthma and atopy is unclear and the answer to the question "does atopy cause asthma?" remains unknown. This review explores the relationship between asthma and atopy from a gene-environment interaction perspective and tackles the question "are similar gene-environment interactions present for asthma and atopy?" The main finding is that gene-environment interactions are described for asthma and atopy in children but these interactions are seldom sought for both asthma and atopy in the same population. In...
Respirology (Carlton, Vic.), 2016
European Respiratory Review, 2015
Management-related issues are an important aspect of monitoring asthma in children in clinical pr... more Management-related issues are an important aspect of monitoring asthma in children in clinical practice. This review summarises the literature on practical aspects of monitoring including adherence to treatment, inhalation technique, ongoing exposure to allergens and irritants, comorbid conditions and side-effects of treatment, as agreed by the European Respiratory Society Task Force on Monitoring Asthma in Childhood.The evidence indicates that it is important to discuss adherence to treatment in a non-confrontational way at every clinic visit, and take into account a patient's illness and medication beliefs. All task force members teach inhalation techniques at least twice when introducing a new inhalation device and then at least annually. Exposure to second-hand tobacco smoke, combustion-derived air pollutants, house dust mites, fungal spores, pollens and pet dander deserve regular attention during follow-up according to most task force members. In addition, allergic rhinitis...
The European respiratory journal, Jan 5, 2015
The goal of asthma treatment is to obtain clinical control and reduce future risks to the patient... more The goal of asthma treatment is to obtain clinical control and reduce future risks to the patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all components of asthma, such as symptoms, lung function, bronchial hyperresponsiveness and inflammation, may exist in various combinations in different individuals, to date there is limited evidence on how to integrate these for optimal monitoring of children with asthma. The aims of this ERS Task Force were to describe the current practise and give an overview of the best available evidence on how to monitor children with asthma. 22 clinical and research experts reviewed the literature. A modified Delphi method and four Task Force meetings were used to reach a consensus. This statement summarises the literature on monitoring children with asthma. Available tools for monitoring children with asthma, such as clinical tools, lung function, bronchial responsiveness and inflammatory markers, are described ...
2014 67th Annual Conference for Protective Relay Engineers, 2014
A numerical generator protection relay provides multiple functions and typically uses algorithms ... more A numerical generator protection relay provides multiple functions and typically uses algorithms that do not work on the same principles as older electromechanical relays. Often relay test personnel still want to use old test methods developed long ago for electromechanical relays. Test results obtained from these old test methods may not be a good indication of whether or not the numerical relay protection functions properly. One such obsolete technique still often used is referred to as a static test. Fault voltage and/or fault current are injected to see if the selected protection function operates at the setpoint and is in tolerance. Many protection functions have dynamic characteristics and/or hidden features that cannot be properly tested using a static test. This paper demonstrates various techniques how to test numerical protection relays such as dynamic tests.
Pediatric Blood & Cancer, 2011
Mental Health Practice, 2007
European Respiratory Journal, 2013
European Respiratory Journal, 2011
European Respiratory Journal, 2012
Archives of Disease in Childhood, 2012
Bronchiolitis is a common lower respiratory tract infection of infancy where management has varie... more Bronchiolitis is a common lower respiratory tract infection of infancy where management has varied considerably in the past. The aim of the present study was to determine whether patient treatment and outcomes changed after introduction of a clinical care pathway. Infants aged up to 6 months admitted to hospital with bronchiolitis were identified as part of an annual audit of bronchiolitis management between winters 2003/2004 and 2009/2010. The primary outcome, duration of stay (DOS), was compared before and after the clinical pathway was introduced before the winter 2005/2006. There were 328 infants identified, mean age 75 days, respiratory syncitial virus was detected in 89%. After the clinical pathway was introduced, the proportion of infants prescribed salbutamol fell from 50% to 8% (p < 0.001) and ipratropium bromide from 38% to 0% (p < 0.001) but the proportion prescribed antibiotics was unchanged. The median DOS was 79 h prior to the clinical pathway and 66 h afterwards (p = 0.010) but there was no difference in days where supplemental oxygen or nasogastric feeding was required. A clinical pathway for the management of acute bronchiolitis can be implemented in the hospital setting and the conservative approach, in particular not prescribing bronchodilators, is not associated with prolonged duration of stay.
Advanced Synthesis & Catalysis, 2012
A new strategy for the synthesis of poly- cyclic imidazole-containing N-heterocycles, based on th... more A new strategy for the synthesis of poly- cyclic imidazole-containing N-heterocycles, based on the two general synthetic ways, namely the Pd(II)- catalyzed intramolecular arylation via CH/CHal and CH/CH coupling reactions, was developed. The method proposed here enables the synthesis of many fused N-heterocycles containing purine, 1-deazapur- ines and benzimidazole structural units.
Acta Crystallographica Section D Biological Crystallography, 1995
Annals of Nigerian Medicine, 2011
The identification of nitric oxide in exhaled breath and its role as a surrogate marker of eosino... more The identification of nitric oxide in exhaled breath and its role as a surrogate marker of eosinophilic inflammation of the airways led to rapid development in the area of its measurement. Standardized measurement techniques have been developed as well as simple, cheap, and reliable equipments. Although a number of factors have been identified as affecting its assay, fractional exhaled nitric oxide (FENO) can reliably be used to distinguish eosinophilic from non-eosinophilic airway inflammation. Unlike the other indirect measures of airway inflammation such as FEV1 reversibility and bronchoprovocative tests, FENO is noninvasive and gives a direct measure of inflammation. There are sufficient data supporting its role in the diagnosis of asthma, monitoring of disease, prediction of relapse, and level of compliance. Measurement of FENO has therefore made the transition from the bench to the bedside. Of recent, there are attempts at devising interpretative strategies for its use in day to day clinical practice.