Sudipta Roy - Academia.edu (original) (raw)
Papers by Sudipta Roy
The developing utility of zebrafish in modeling neurobehavioral disorders. A Stewart, F Kadri, J ... more The developing utility of zebrafish in modeling neurobehavioral disorders. A Stewart, F Kadri, J DiLeo, K Chung, J Cachat, J Goodspeed, C Suciu, S Roy, S Gaikwad, K Wong, M Elegante, S Elkhayat, N Wu, T Gilder, D Tien, L Grossman, J Tan, A Denmark, B Bartels, K Frank, E Beeson, AV Kalueff Int J Comp Psychol 23:11, 104-121, 2010.
Behavioural Brain Research, 2010
The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral neuroscienc... more The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral neuroscience research. Zebrafish behavior is robustly affected by environmental and pharmacological manipulations, and can be examined using exploration-based paradigms, paralleled by analysis of endocrine (cortisol) stress responses. Discontinuation of various psychotropic drugs evokes withdrawal in both humans and rodents, characterized by increased anxiety. Sensitivity of zebrafish to drugs of abuse has been recently reported in the literature. Here we examine the effects of ethanol, diazepam, morphine and caffeine withdrawal on zebrafish behavior. Overall, discontinuation of ethanol, diazepam and morphine produced anxiogenic-like behavioral or endocrine responses, demonstrating the utility of zebrafish in translational research of withdrawal syndrome.
The developing utility of zebrafish in modeling neurobehavioral disorders. A Stewart, F Kadri, J ... more The developing utility of zebrafish in modeling neurobehavioral disorders. A Stewart, F Kadri, J DiLeo, K Chung, J Cachat, J Goodspeed, C Suciu, S Roy, S Gaikwad, K Wong, M Elegante, S Elkhayat, N Wu, T Gilder, D Tien, L Grossman, J Tan, A Denmark, B Bartels, K Frank, E Beeson, AV Kalueff Int J Comp Psychol 23:11, 104-121, 2010.
Behavioural Brain Research, 2010
The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral neuroscienc... more The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral neuroscience research. Zebrafish behavior is robustly affected by environmental and pharmacological manipulations, and can be examined using exploration-based paradigms, paralleled by analysis of endocrine (cortisol) stress responses. Discontinuation of various psychotropic drugs evokes withdrawal in both humans and rodents, characterized by increased anxiety. Sensitivity of zebrafish to drugs of abuse has been recently reported in the literature. Here we examine the effects of ethanol, diazepam, morphine and caffeine withdrawal on zebrafish behavior. Overall, discontinuation of ethanol, diazepam and morphine produced anxiogenic-like behavioral or endocrine responses, demonstrating the utility of zebrafish in translational research of withdrawal syndrome.