Süleyman Durmaz - Academia.edu (original) (raw)

Papers by Süleyman Durmaz

Dicle Tıp Dergisi, 2012

ÖZET Amaç: Bu çalışmada çeşitli klinik örneklerden soyutlanan Candida albicans dışı mayaların tür... more ÖZET Amaç: Bu çalışmada çeşitli klinik örneklerden soyutlanan Candida albicans dışı mayaların tür düzeyinde tanımlanmasında VITEK 2 YST kart (bioMérieux, Fransa) kullanılarak elde edilen sonuçların API 20C AUX (bioMérieux, Fransa) sistemi ile ...

Microbial Pathogenesis, Feb 1, 2023

Journal of Infection and Chemotherapy, Sep 1, 2016

Candida spp. are the most common opportunistic mycosis worldwide. Although Candida albicans is th... more Candida spp. are the most common opportunistic mycosis worldwide. Although Candida albicans is the most common cause of urinary tract infections, the frequency of non-albicans Candida species is increasing with common use of antifungal in the prophylaxis and treatment. This may lead to difficulties in treatment. Antifungal tests should be applied with identification of species for effective treatment. In this study, identification of Candida species isolated from urine culture and investigation of susceptibility of these strains to amphotericin B, flucytosine, fluconazole, voriconazole was aimed. In this study, 58 Candida strains isolated from urine cultures at Osmaniye State Hospital between January 2012 and April 2013 were included. Urine culture and antifungal susceptibility tests were applied. Incidence rate of Candida spp. was determined as C. albicans (56.9%), Candida glabrata (20.6%), Candida tropicalis (10.3%), Candida parapsilosis (7%), Candida krusei (3.4%), Candida kefyr (1.8%). Most of the isolates were susceptible to amphotericin B, flucytosine, fluconazole, voriconazole. Twenty three (39.7%) Candida strains were isolated from internal medical branches and Intensive Care Unit and 12 (20.6%) from the Surgical Medical Branches. C. albicans and C. glabrata species were isolated most frequently as a candiduria factor in this hospital between January 2012 and April 2013. The analysis of antifungal susceptibility profile shows no significant resistance to antifungals.

Journal of Cosmetic Dermatology, Oct 5, 2020

BackgroundDemodex folliculorum mite infestation is associated with many diseases such as rosacea,... more BackgroundDemodex folliculorum mite infestation is associated with many diseases such as rosacea, pityriasis found with acne vulgaris, and blepharitis.AimIn this research, the aim of this study was to investigate an association between patients who have metabolic syndrome and presence of Demodex folliculorum.Patients/MethodsThis research was planned prospectively as a case‐control study. Fifty cases who have metabolic syndrome and 50 control subjects in good health were included. Metabolic syndrome was diagnosed according to the NCEP Adult Treatment Panel III criteria. Standard superficial skin biopsy was performed for the presence of Demodex folliculorum mite infestation.ResultsIt was detected that number of Demodex affected from the glucose level and each increase in glucose level cause an increase on Demodex as 0.190 (P = .00, t = 4.746, B = 0.190, r = 0.57, Durbin‐Watson = 1.801, confidence interval = 0.110 to 0.271 (for glucose)).ConclusionIn this study, the presence of Demodex folliculorum was found to be higher in the cases who have metabolic syndrome compared to the healthy group. These results show that in cases with metabolic syndrome, high blood sugar levels make them more susceptible to infestation of Demodex folliculorum.

European journal of basic medical sciences, Jun 1, 2014

Chronic atrophic rhinitis which is also known as empty nose syndrome or ozena is a chronic diseas... more Chronic atrophic rhinitis which is also known as empty nose syndrome or ozena is a chronic disease manifested with atrophy of the nasal mucosa, nasal crusting and foul-smelling discharge, and could progress to destruction of nasal bones, and anosmia. It is a rare disease especially seen in young women with low socioeconomic level living in subtropical countries with poor hygienic conditions. In this study, a 9 year old male patient with chronic atrophic rhinitis caused by K. ozaenae is presented. Male patient admitted to the earnose-throat outpatient clinic with complaints of two years history of, nasal congestion, foul smelling discharge. Physical examination revealed yellowgreen crusts in nasal cavity, enlarged nasal cavity, postnasal drip, and atrophic turbinate and mucosa, nasal cultures taken from patient revealed K. ozaenae. Computer tomografie scan showed poor sinus development and ventilation. According to the results of the antibiotic sensitivity test 2x500 mg ceftriaxone treatment initiated, with twice daily nasal irrigation and moisturizing, The patients complaints disappeared three weeks later and anitibiotic treatment terminated. Continuation of nasal irrigation and moisturizing and regular follow up controls recommended after termination of antibiotic. In order to avoid delay of diagnosis; K. ozaenae induced atrophic rhinitis should be considered as a diagnosis in the presence of long lasting foul-smelling discharge, nasal congestion, and recurrent complaints despite long-term antibiotic therapy even in childhood.

Electronic journal of general medicine, Apr 6, 2016

African Journal of Microbiology Research, Mar 4, 2011

The aim of this study was to investigate Epstein-Barr virus (EBV) serology and EBV DNA in the pat... more The aim of this study was to investigate Epstein-Barr virus (EBV) serology and EBV DNA in the patients with bone marrow transplantation. In the current study, 128 patients with bone marrow transplantation (BMT) were included in Hematology-Oncology Department of Medical Faculty, Erciyes University between June 2005 and October 2009. In order to evaluate EBV serology and DNA, 357 samples obtained from the patients were studied with enzyme-linked immunosorbent assay and real-time polymerase chain reaction (PCR). The components of EBV serology were anti-Ebstein-Barr nuclear antigen (EBNA)-1 IgG, anti-viral capsid antigen (VCA) IgG and IgM. EBV seropositivity was found in 98.4% of the samples. EBV DNA positivity was detected in 13.3% of the patients. High viral load was only seen in one patient among all the EBV DNA positivity. No patient showed any symptoms regarding EBV virus and admitted with post-transplant lymphoproliferative disease. In conclusion, for the diagnosis and follow up of EBV infections in patients with BMT, detection of EBV DNA by PCR method is also beneficial in addition to serological tests regarding EBV. Key words: Epstein-Barr virus, serological markers, real-time PCR, bone marrow transplant recipients.

Biomedical Research-tokyo, 2015

Pakistan Journal of Medical Sciences, Sep 16, 2015

Journal of Hospital Infection, Jun 1, 2013

Electronic journal of general medicine, Oct 15, 2014

THE ULUTAS MEDICAL JOURNAL, 2015

Objective: The aim of this study was to determine the enterococci species and antimicrobial resis... more Objective: The aim of this study was to determine the enterococci species and antimicrobial resistance rates of enteroccus strains isolated from blood cultures of inpatients. Materials and Methods: One hundred five Enterococcus spp. strains isolated from blood cultures sent from clinics at Osmaniye State Hospital Microbiology Laboratory between January 2011-December 2013 were included. The isolates were identified by conventional methods and Vitek 2 automated system. Antibiotic susceptibility tests were performed by disk-diffusion method and E-test. Statistical analysis was performed using chi-square test. Results: Enterococcus spp. strains evaluated, 54(51.4%) were identified as E.faecalis and 51(48.6%) as E.faecium. General Intensive Care Unit(GICU) is the section where most frequently isolated species of both enterococci. Other clinics were Dialysis unit, and Internal Medicine clinics. E.faecium strains were found to be resistant to ampicillin, erythromycin, ciprofloxacin. Resistance rates of E.faecalis strains against ampicillin, erythromycin, ciprofloxacin were 47%, 70.5%, 11.8%, respectively. High-level resistance to gentamicin and streptomycin were determined in 55.6%, 83.3% of E.faecium strains and in 23.5%, 11.8% of E.faecalis strains, respectively (p≤0.05). Two of E.faecium strains and 1 of E.faecalis from GICU were found to be resistant to teicoplanin and vancomycin. Linezolid was found most effective drug and resistance wasn’t determined in none of the strains. Conclusions: Three vancomycin and teicoplanin resistant strains isolated from blood cultures in our hospital show that the isolates mentioned above may cause significant problems in the future. In addition, linezolid may be a good alternative for the treatment of the resistant enterococcal infections in our hospital.

Russian Open Medical Journal, 2015

The first cases with vancomycin-resistant Enterococci (VRE) isolation were reported in 1988 throu... more The first cases with vancomycin-resistant Enterococci (VRE) isolation were reported in 1988 throughout the world, and in 1998 in Turkey. The number of the papers conducted on cases or epidemics in which VRE was isolated is in increase. In this study, it was aimed to evaluate some studies at this topic. In conclusion, it was observed that the VRE strains isolated in the same clinic within a short period had a high probability to be the same clone, that there was need for extra investigation for teicoplanin resistance in VRE strains in terms of vanB expression, that VRE colonisation was more common in patients with long term intensive care unit stay, and that eradication of VRE could be made with more strict precautions in comparison to other epidemic bacteria.

The aim of the study is to investigate susceptibility of staphylococci strains isolated from vari... more The aim of the study is to investigate susceptibility of staphylococci strains isolated from various clinical samples to quinupristin-dalfopristin. The ninety-eight strains of staphylococci [74 coagulase-negative staphylococci (CNSs) and 24 S. aureus] isolated from various clinical samples were included the study which had been sent to microbiology laboratory. Staphylococci strains were identified by using conventional methods. Methicillin and quinupristin-dalfopristin susceptibility of staphylococci strains were performed by Kirby-Bauer's disc diffusion method according to the Clinical and Laboratory Standards Institute criteria. Also, vancomycin susceptibility of strains was investigated by E-test method. Strain of S. aureus ATCC 25923 was used as the quality control strain. The fifty-three (72%) strains of the CNSs were defined as methicillinresistant CNS (MR-CNS), three (13%) strains of S. aureus was defined as methicillin-resistant S. aureus (MRSA). The eight (15%) strains of MR-CNS were found resistant to quinupristin-dalfopristin, one (5%) strain of MS-CNS were found resistant to quinupristin-dalfopristin. None of MSSA or MRSA strains were resistant to quinupristin-dalfopristin. All of the strains were found as susceptible to vancomycin. Strains of staphylococci were found susceptible to quinupristin-dalfopristin at high rates. Consequently we think that quinupristin-dalfopristin combination may be an alternative option for treatment of resistant Gram-positive cocci infections like vancomycin.