Ryan Sun - Academia.edu (original) (raw)

Papers by Ryan Sun

Research paper thumbnail of SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition

Biomedical Optics Express, 2010

Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal str... more Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal structure, function, and disease. Highspeed, high resolution imaging can reveal dynamic events such as changes in blood flow and responses to stimulation. Despite these benefits, commercially available scientific cameras rarely include software that is suitable for in-vivo imaging applications, making this highly versatile form of optical imaging challenging and time-consuming to implement. To address this issue, we have developed a novel, open-source software package to control high-speed, multispectral optical imaging systems. The software integrates a number of modular functions through a custom graphical user interface (GUI) and provides extensive control over a wide range of inexpensive IEEE 1394 Firewire cameras. Multispectral illumination can be incorporated through the use of off-the-shelf light emitting diodes which the software synchronizes to image acquisition via a programmed microcontroller, allowing arbitrary high-speed illumination sequences. The complete software suite is available for free download. Here we describe the software's framework and provide details to guide users with development of this and similar software.

Research paper thumbnail of SHORT COMMUNICATIONIntrahaemocytic activity of lysosomal enzymes in Penaeus monodon and Macrobrachium rosenbergii

Fish & Shellfish Immunology, 1999

Research paper thumbnail of USE OF MONOCLONAL ANTIBODIES TO CLASSIFY HEMOCYTE SUBPOPULATIONS OF TIGER SHRIMP (PENAEUS MONODON

Journal of Crustacean Biology, 2002

... It is also known that cellular defense reactions in tiger shrimp include the production of su... more ... It is also known that cellular defense reactions in tiger shrimp include the production of superoxide anion and hydrogen peroxide (Song and Hsieh, 1994), phagocytosis, nodule formation (Sung and Song, 1996), activations of prophenoloxidase system (Sung et al., 1994, 1996 ...

Research paper thumbnail of Diffusion-weighted MRI: influence of intravoxel fat signal and breast density on breast tumor conspicuity and apparent diffusion coefficient measurements

Magnetic Resonance Imaging, 2011

Promising recent investigations have shown that breast malignancies exhibit restricted diffusion ... more Promising recent investigations have shown that breast malignancies exhibit restricted diffusion on diffusion-weighted imaging (DWI) and may be distinguished from normal tissue and benign lesions in the breast based on differences in apparent diffusion coefficient (ADC) values. In this study, we assessed the influence of intravoxel fat signal on breast diffusion measures by comparing ADC values obtained using a diffusion-weighted single shot fast spin echo sequence with and without fat suppression. The influence of breast density on ADC measures was also evaluated. ADC values were calculated for both tumor and normal fibroglandular tissue in a group of twenty-one women with diagnosed breast cancer. There were systematic underestimations of ADC for both tumor and normal breast tissue due to intravoxel contribution from fat signal on non-fat-suppressed DWI. This ADC underestimation was more pronounced for normal tissue values (mean difference = 40%) than for tumors (mean difference = 27%, p<0.001) and was worse in women with low breast tissue density versus those with extremely dense breasts (p<0.05 for both tumor and normal tissue). Tumor conspicuity measured by contrast-to-noise ratio was significantly higher on ADC maps created with fat suppression and was not significantly associated with breast density. In summary, robust fat suppression is important for accurate breast ADC measures and optimal lesion conspicuity on DWI.

Research paper thumbnail of Southern Illinois University Carbondale The Convergence of Conventional Media and New Technology in the Cases of The New York Times and National Broadcasting Company (NBC

During the last decade, the fast development of new technologies: the Internet, personal computer... more During the last decade, the fast development of new technologies: the Internet, personal computer, portable electronic device, etc., have powerful influences on people's life especially their consuming behavior. By making consumer's lives easier, technologies also empower them through more choices on merchandise. Meanwhile, new technologies also drive enterprises, particular media companies, to operate with state-of-the-art techniques, physically as well as structurally. This research project studies the convergence of conventional media with new technologies by focusing on the managerial issues with convergence and business strategies that conventional media companies are using. In this project, it will concentrate on the newspaper and television sector of conventional media industry, there are two case studies: The New York Times and National Broadcasting

Research paper thumbnail of SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition

Biomedical Optics Express, 2010

Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal str... more Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal structure, function, and disease. Highspeed, high resolution imaging can reveal dynamic events such as changes in blood flow and responses to stimulation. Despite these benefits, commercially available scientific cameras rarely include software that is suitable for in-vivo imaging applications, making this highly versatile form of optical imaging challenging and time-consuming to implement. To address this issue, we have developed a novel, open-source software package to control high-speed, multispectral optical imaging systems. The software integrates a number of modular functions through a custom graphical user interface (GUI) and provides extensive control over a wide range of inexpensive IEEE 1394 Firewire cameras. Multispectral illumination can be incorporated through the use of off-the-shelf light emitting diodes which the software synchronizes to image acquisition via a programmed microcontroller, allowing arbitrary high-speed illumination sequences. The complete software suite is available for free download. Here we describe the software's framework and provide details to guide users with development of this and similar software.

Research paper thumbnail of SHORT COMMUNICATIONIntrahaemocytic activity of lysosomal enzymes in Penaeus monodon and Macrobrachium rosenbergii

Fish & Shellfish Immunology, 1999

Research paper thumbnail of USE OF MONOCLONAL ANTIBODIES TO CLASSIFY HEMOCYTE SUBPOPULATIONS OF TIGER SHRIMP (PENAEUS MONODON

Journal of Crustacean Biology, 2002

... It is also known that cellular defense reactions in tiger shrimp include the production of su... more ... It is also known that cellular defense reactions in tiger shrimp include the production of superoxide anion and hydrogen peroxide (Song and Hsieh, 1994), phagocytosis, nodule formation (Sung and Song, 1996), activations of prophenoloxidase system (Sung et al., 1994, 1996 ...

Research paper thumbnail of Diffusion-weighted MRI: influence of intravoxel fat signal and breast density on breast tumor conspicuity and apparent diffusion coefficient measurements

Magnetic Resonance Imaging, 2011

Promising recent investigations have shown that breast malignancies exhibit restricted diffusion ... more Promising recent investigations have shown that breast malignancies exhibit restricted diffusion on diffusion-weighted imaging (DWI) and may be distinguished from normal tissue and benign lesions in the breast based on differences in apparent diffusion coefficient (ADC) values. In this study, we assessed the influence of intravoxel fat signal on breast diffusion measures by comparing ADC values obtained using a diffusion-weighted single shot fast spin echo sequence with and without fat suppression. The influence of breast density on ADC measures was also evaluated. ADC values were calculated for both tumor and normal fibroglandular tissue in a group of twenty-one women with diagnosed breast cancer. There were systematic underestimations of ADC for both tumor and normal breast tissue due to intravoxel contribution from fat signal on non-fat-suppressed DWI. This ADC underestimation was more pronounced for normal tissue values (mean difference = 40%) than for tumors (mean difference = 27%, p<0.001) and was worse in women with low breast tissue density versus those with extremely dense breasts (p<0.05 for both tumor and normal tissue). Tumor conspicuity measured by contrast-to-noise ratio was significantly higher on ADC maps created with fat suppression and was not significantly associated with breast density. In summary, robust fat suppression is important for accurate breast ADC measures and optimal lesion conspicuity on DWI.

Research paper thumbnail of Southern Illinois University Carbondale The Convergence of Conventional Media and New Technology in the Cases of The New York Times and National Broadcasting Company (NBC

During the last decade, the fast development of new technologies: the Internet, personal computer... more During the last decade, the fast development of new technologies: the Internet, personal computer, portable electronic device, etc., have powerful influences on people's life especially their consuming behavior. By making consumer's lives easier, technologies also empower them through more choices on merchandise. Meanwhile, new technologies also drive enterprises, particular media companies, to operate with state-of-the-art techniques, physically as well as structurally. This research project studies the convergence of conventional media with new technologies by focusing on the managerial issues with convergence and business strategies that conventional media companies are using. In this project, it will concentrate on the newspaper and television sector of conventional media industry, there are two case studies: The New York Times and National Broadcasting