Suneet Sood - Academia.edu (original) (raw)
Papers by Suneet Sood
Regional Conference on Science, Technology and Social Sciences (RCSTSS 2014), 2016
Journal of Medical Case Reports, 2010
Introduction: Isolated lymphedema of the penis is extremely rare: combined involvement of the scr... more Introduction: Isolated lymphedema of the penis is extremely rare: combined involvement of the scrotum and penis is the norm. Furunculosis as a cause is not, to our knowledge, previously reported. We present a case of isolated penile lymphedema that responded to excision of lymphedematous tissue and reconstruction with flaps.
The Medical journal of Malaysia, 2011
The management of irreducible rectal prolapse is controversial. Surgeons may attempt conservative... more The management of irreducible rectal prolapse is controversial. Surgeons may attempt conservative management by application of sugar. When surgery becomes inevitable the choice of procedure varies. We reviewed eight cases and noted the clinical findings and the results of conservative and surgical management. In four cases sugar was applied first, and failed. Emergency surgery always gave good outcomes. The procedures included simple reduction, rectopexy, laparotomy with resection, Delorme's repair, and perineal resection. Our experience and review of the literature indicate that surgery should be performed early in irreducible prolapse. Perineal resection may be the most suitable emergency procedure.
The Journal of Trauma: Injury, Infection, and Critical Care, 1988
Two-wheeler trauma in developing countries differs in some respects when compared to that in deve... more Two-wheeler trauma in developing countries differs in some respects when compared to that in developed countries. A total of 302 cases involved in motorcycle, scooter, and moped accidents were analyzed. There were 201 drivers and 101 passengers. Injury severity scores (ISS), overall number of wounds, and number of fractures were studied. Motorcycle riders had a significantly higher ISS than did scooter riders. Persons involved in collisions with other powered vehicles had 36% more fractures and higher ISS than those involved in accidents where no collision occurred with a powered vehicle. Female passengers, sitting sideways, and involved in collisions, sustained fewer injuries than did a comparable group of male passengers who sat astride; the ISS of female passengers was also lower. Helmet users had a much lower incidence and severity of head injury than riders who did not use helmets. Turbans appeared to offer partial protection from head injury.
Annals of Surgery, 1974
Among 69 patients with PVT, 338 variceal bleeding episodes occurred. Only two patients died from ... more Among 69 patients with PVT, 338 variceal bleeding episodes occurred. Only two patients died from bleeding, and both lived in remote communities and were inaccessible to medical care. Fifty-three children underwent 164 operations for the management of PVT. Once operative management was undertaken, subsequent operations frequently were necessary. Nonoperative measures controlled acute variceal hemorrhage in most instances during the past 10 years. Almost all patients who underwent splenectojny alone, variceal ligation, gastric division, splenic transposition, or makeshift shunts subsequently rebled. These operations are rarely indicated in the current management of children with PVT. Portal venography is essential to define the portal venous circulation before a shunt operation is attempted. Cavomesenteric or central splenorenal shunts prevented further bleeding in eight of 15 patients and are the most reliable operations to control bleeding in patients with PVT. Emergency operation is rarely necessary to control bleeding. Sixteen patients (average age 14.6 years) with PVT did not undergo any operations, and are alive. Each of the six patients with PVT who died from complications of portal hypertension did so within nine months of an operation. Four of these patients had previous splenectomy and died with sepsis as one of the major factors. Bleeding episodes became less frequent as the patients increased in age. Patients who underwent shunts under unfavorable circumstances or who received various other operations to treat portal hypertension appeared to have a higher risk of morbidity and mortality than those managed nonoperatively. E XTRAHEPAnC portal venous thrombosis (PVT) has been recognized as the most frequent cause of portal hypertension in children, yet scant information has been recorded to indicate the long-term prognosis for patients with this condition. Since Clatworthy and associates24 summarized the manifestations of PVT and recom-From the
Cardiac metastases are among the topics with limited systematic reviews. Theoretically, the heart... more Cardiac metastases are among the topics with limited systematic reviews. Theoretically, the heart can be infiltrated by any malignancy with the ability to spread to distant structures. Thus far, no specific tumors are known to have a predilection for the heart, but some do metastasize more often than others, for example, melanoma and primary mediastinal tumors. We report a case of cardiac metastasis from a diffuse large B cell lymphoma in a young man. The peculiarity of this case is that besides the involvement of right ventricle and atrium, the tricuspid valve was also infiltrated. Valvular metastasis is rarely reported in the medical literature.
Blood purification, 2014
To measure plasma pro-apoptotic and pro-necrotic activity in severe acute kidney injury (AKI) pat... more To measure plasma pro-apoptotic and pro-necrotic activity in severe acute kidney injury (AKI) patients within a randomized controlled trial of continuous veno-venous hemofiltration with high cut-off filters (CVVH-HCO) versus standard filters (CVVH-Std). We measured pro-apoptotic and pro-necrotic plasma activity by trypan blue exclusion cell viability assay, detection of DNA fragmentation, and by determination of caspase-3 activity and annexin V-based apoptosis and necrosis detection assay. Compared to no apoptosis or necrosis after incubation with healthy plasma, 14-18% of cells showed apoptosis and 4-8% showed necrosis after incubation with plasma from AKI patients. When comparing different measures of pro-apoptotic or pro-necrotic activity, CVVH-HCO and CVVH-Std showed no differential effects on such activity, which remained high over the first 3 days of treatment. However, using annexin V-FITC, there was a significant drop in pro-apoptotic activity across the filter for the CVVH-...
Open Journal of Preventive Medicine, 2014
Introduction: The Health Enhancement Module (HEM) is taught as a core curriculum for all medical ... more Introduction: The Health Enhancement Module (HEM) is taught as a core curriculum for all medical students at Monash University since 2002. In 2012 we moved the year three content of the program into a community setting, calling it the Health Enhancement Carnival (HEC). At the carnival, our undergraduates interacted with school students, their teachers, and their parents, involving them in a mix of discussions, poster presentations, and video presentations. In this paper we present our experience with the HEC. Specifically, we looked at the following two measures: how did the HEC influence the knowledge, attitude, and practice of healthy living among medical students? And, what were the learning experiences of the students during the HEC? Methods: Five themes (exercise, food, healthy sleep, workplace stress and ageing) were divided among students. They were asked to develop those themes with the help of posters, power point presentations, community talks as well as video presentations. The carnival was held in the setting of two nearby children's schools. Students were evaluated by a panel of examiners with regards to learning objectives as well as preparation and presentation. As part of evaluation, we developed 2 questionnaires. The HEP Healthy Living Questionnaire provided feedback on how the program had improved students' knowledge, attitudes, and practice of healthy living. The HEP Learning Style Questionnaire covered twelve areas, including collegiality, environment, leadership, community interaction and other facets of learning style. Analyses were performed using the IBM SPSS Statistics version 20 software in the Clinical School Johor Bahru. Results: 1) Influence of HEC on the knowledge, attitude, and practice of healthy living among medical students. From the interviews, the judges gave the students mean ratings of 4.0/5. We also received 77 out of 127 feedback questionnaires (response rate: 60.6%) from the students. Most students (range: 49.35% to 55.84%) were "satisfied/totally satisfied", "achieved/totally achieved", or "improved/totally improved" to 5 questions of the Healthy Living Questionnaire. Correlation coefficients between knowledge of healthy living, attitude towards healthy living, and practice of healthy living were large (exceeding 0.8) suggesting that these three measures were highly and positively inter-correlated. Most students (range: 60.28% to 71.43%) scored "a lot/almost all", to 5 questions regarding achievement A. Gandhi et al. 772 of learning objectives. 2) Learning experiences of the students during the HEC. Responding to the HEP Learning Style Questionnaire, most students (range: 66.24% to 85.72%) agreed or strongly agreed that the program provided an optimal environment for learning, encouraging students to assume leadership responsibilities and promoting self-directed learning. A correlation matrix of the 12 items showed medium to large correlations between all twelve variables. Conclusions: The Health Enhancement Program (HEP) is an innovative approach that has enabled students to learn about healthy living within the context of the local community.
Therapeutic Drug Monitoring, 2013
Background: Dihydropyrimidine dehydrogenase (DPD) is a pyrimidine catabolic enzyme involved in th... more Background: Dihydropyrimidine dehydrogenase (DPD) is a pyrimidine catabolic enzyme involved in the initial and rate-limiting step of the catabolic pathway of toxic metabolites of 5-fluorouracil (5-FU). Several studies have reported that deficiency of DPD and polymorphisms of its gene are related to 5-FU toxicities and death. Association between serum concentration of 5-FU and its related toxicity has also been previously demonstrated. Hence, this study aims to understand the role of DPYD variants in serum level of 5-FU and the risk of developing toxicity to prevent adverse reactions and maximize therapy outcome for personalized medicine.
Indian Journal of Plastic Surgery, 2012
Regional Conference on Science, Technology and Social Sciences (RCSTSS 2014), 2016
Journal of Medical Case Reports, 2010
Introduction: Isolated lymphedema of the penis is extremely rare: combined involvement of the scr... more Introduction: Isolated lymphedema of the penis is extremely rare: combined involvement of the scrotum and penis is the norm. Furunculosis as a cause is not, to our knowledge, previously reported. We present a case of isolated penile lymphedema that responded to excision of lymphedematous tissue and reconstruction with flaps.
The Medical journal of Malaysia, 2011
The management of irreducible rectal prolapse is controversial. Surgeons may attempt conservative... more The management of irreducible rectal prolapse is controversial. Surgeons may attempt conservative management by application of sugar. When surgery becomes inevitable the choice of procedure varies. We reviewed eight cases and noted the clinical findings and the results of conservative and surgical management. In four cases sugar was applied first, and failed. Emergency surgery always gave good outcomes. The procedures included simple reduction, rectopexy, laparotomy with resection, Delorme's repair, and perineal resection. Our experience and review of the literature indicate that surgery should be performed early in irreducible prolapse. Perineal resection may be the most suitable emergency procedure.
The Journal of Trauma: Injury, Infection, and Critical Care, 1988
Two-wheeler trauma in developing countries differs in some respects when compared to that in deve... more Two-wheeler trauma in developing countries differs in some respects when compared to that in developed countries. A total of 302 cases involved in motorcycle, scooter, and moped accidents were analyzed. There were 201 drivers and 101 passengers. Injury severity scores (ISS), overall number of wounds, and number of fractures were studied. Motorcycle riders had a significantly higher ISS than did scooter riders. Persons involved in collisions with other powered vehicles had 36% more fractures and higher ISS than those involved in accidents where no collision occurred with a powered vehicle. Female passengers, sitting sideways, and involved in collisions, sustained fewer injuries than did a comparable group of male passengers who sat astride; the ISS of female passengers was also lower. Helmet users had a much lower incidence and severity of head injury than riders who did not use helmets. Turbans appeared to offer partial protection from head injury.
Annals of Surgery, 1974
Among 69 patients with PVT, 338 variceal bleeding episodes occurred. Only two patients died from ... more Among 69 patients with PVT, 338 variceal bleeding episodes occurred. Only two patients died from bleeding, and both lived in remote communities and were inaccessible to medical care. Fifty-three children underwent 164 operations for the management of PVT. Once operative management was undertaken, subsequent operations frequently were necessary. Nonoperative measures controlled acute variceal hemorrhage in most instances during the past 10 years. Almost all patients who underwent splenectojny alone, variceal ligation, gastric division, splenic transposition, or makeshift shunts subsequently rebled. These operations are rarely indicated in the current management of children with PVT. Portal venography is essential to define the portal venous circulation before a shunt operation is attempted. Cavomesenteric or central splenorenal shunts prevented further bleeding in eight of 15 patients and are the most reliable operations to control bleeding in patients with PVT. Emergency operation is rarely necessary to control bleeding. Sixteen patients (average age 14.6 years) with PVT did not undergo any operations, and are alive. Each of the six patients with PVT who died from complications of portal hypertension did so within nine months of an operation. Four of these patients had previous splenectomy and died with sepsis as one of the major factors. Bleeding episodes became less frequent as the patients increased in age. Patients who underwent shunts under unfavorable circumstances or who received various other operations to treat portal hypertension appeared to have a higher risk of morbidity and mortality than those managed nonoperatively. E XTRAHEPAnC portal venous thrombosis (PVT) has been recognized as the most frequent cause of portal hypertension in children, yet scant information has been recorded to indicate the long-term prognosis for patients with this condition. Since Clatworthy and associates24 summarized the manifestations of PVT and recom-From the
Cardiac metastases are among the topics with limited systematic reviews. Theoretically, the heart... more Cardiac metastases are among the topics with limited systematic reviews. Theoretically, the heart can be infiltrated by any malignancy with the ability to spread to distant structures. Thus far, no specific tumors are known to have a predilection for the heart, but some do metastasize more often than others, for example, melanoma and primary mediastinal tumors. We report a case of cardiac metastasis from a diffuse large B cell lymphoma in a young man. The peculiarity of this case is that besides the involvement of right ventricle and atrium, the tricuspid valve was also infiltrated. Valvular metastasis is rarely reported in the medical literature.
Blood purification, 2014
To measure plasma pro-apoptotic and pro-necrotic activity in severe acute kidney injury (AKI) pat... more To measure plasma pro-apoptotic and pro-necrotic activity in severe acute kidney injury (AKI) patients within a randomized controlled trial of continuous veno-venous hemofiltration with high cut-off filters (CVVH-HCO) versus standard filters (CVVH-Std). We measured pro-apoptotic and pro-necrotic plasma activity by trypan blue exclusion cell viability assay, detection of DNA fragmentation, and by determination of caspase-3 activity and annexin V-based apoptosis and necrosis detection assay. Compared to no apoptosis or necrosis after incubation with healthy plasma, 14-18% of cells showed apoptosis and 4-8% showed necrosis after incubation with plasma from AKI patients. When comparing different measures of pro-apoptotic or pro-necrotic activity, CVVH-HCO and CVVH-Std showed no differential effects on such activity, which remained high over the first 3 days of treatment. However, using annexin V-FITC, there was a significant drop in pro-apoptotic activity across the filter for the CVVH-...
Open Journal of Preventive Medicine, 2014
Introduction: The Health Enhancement Module (HEM) is taught as a core curriculum for all medical ... more Introduction: The Health Enhancement Module (HEM) is taught as a core curriculum for all medical students at Monash University since 2002. In 2012 we moved the year three content of the program into a community setting, calling it the Health Enhancement Carnival (HEC). At the carnival, our undergraduates interacted with school students, their teachers, and their parents, involving them in a mix of discussions, poster presentations, and video presentations. In this paper we present our experience with the HEC. Specifically, we looked at the following two measures: how did the HEC influence the knowledge, attitude, and practice of healthy living among medical students? And, what were the learning experiences of the students during the HEC? Methods: Five themes (exercise, food, healthy sleep, workplace stress and ageing) were divided among students. They were asked to develop those themes with the help of posters, power point presentations, community talks as well as video presentations. The carnival was held in the setting of two nearby children's schools. Students were evaluated by a panel of examiners with regards to learning objectives as well as preparation and presentation. As part of evaluation, we developed 2 questionnaires. The HEP Healthy Living Questionnaire provided feedback on how the program had improved students' knowledge, attitudes, and practice of healthy living. The HEP Learning Style Questionnaire covered twelve areas, including collegiality, environment, leadership, community interaction and other facets of learning style. Analyses were performed using the IBM SPSS Statistics version 20 software in the Clinical School Johor Bahru. Results: 1) Influence of HEC on the knowledge, attitude, and practice of healthy living among medical students. From the interviews, the judges gave the students mean ratings of 4.0/5. We also received 77 out of 127 feedback questionnaires (response rate: 60.6%) from the students. Most students (range: 49.35% to 55.84%) were "satisfied/totally satisfied", "achieved/totally achieved", or "improved/totally improved" to 5 questions of the Healthy Living Questionnaire. Correlation coefficients between knowledge of healthy living, attitude towards healthy living, and practice of healthy living were large (exceeding 0.8) suggesting that these three measures were highly and positively inter-correlated. Most students (range: 60.28% to 71.43%) scored "a lot/almost all", to 5 questions regarding achievement A. Gandhi et al. 772 of learning objectives. 2) Learning experiences of the students during the HEC. Responding to the HEP Learning Style Questionnaire, most students (range: 66.24% to 85.72%) agreed or strongly agreed that the program provided an optimal environment for learning, encouraging students to assume leadership responsibilities and promoting self-directed learning. A correlation matrix of the 12 items showed medium to large correlations between all twelve variables. Conclusions: The Health Enhancement Program (HEP) is an innovative approach that has enabled students to learn about healthy living within the context of the local community.
Therapeutic Drug Monitoring, 2013
Background: Dihydropyrimidine dehydrogenase (DPD) is a pyrimidine catabolic enzyme involved in th... more Background: Dihydropyrimidine dehydrogenase (DPD) is a pyrimidine catabolic enzyme involved in the initial and rate-limiting step of the catabolic pathway of toxic metabolites of 5-fluorouracil (5-FU). Several studies have reported that deficiency of DPD and polymorphisms of its gene are related to 5-FU toxicities and death. Association between serum concentration of 5-FU and its related toxicity has also been previously demonstrated. Hence, this study aims to understand the role of DPYD variants in serum level of 5-FU and the risk of developing toxicity to prevent adverse reactions and maximize therapy outcome for personalized medicine.
Indian Journal of Plastic Surgery, 2012