Suparna Mukherji - Academia.edu (original) (raw)

Publications by Suparna Mukherji

Research paper thumbnail of Antimicrobial chitosan-PVA hydrogel as a nanoreactor and immobilization matrix for silver nanoparticles

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Research paper thumbnail of Size-controlled silver nanoparticles synthesized over the range 5-100 nm using the same protocol and their antibacterial efficacy

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Papers by Suparna Mukherji

Research paper thumbnail of Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Routledge Open Research

Background: This paper examines the suitability of extant governance frameworks at an internation... more Background: This paper examines the suitability of extant governance frameworks at an international level for addressing antimicrobial resistance (AMR), which is a creeping crisis for global health security. Methods: Our study begins by evaluating the place of antimicrobial resistance (AMR) within United Nations (UN) Sustainable Development Goals (SDG) targets and indicators. This is followed by a discussion of the global health security agenda (GHSA). We examine how AMR needs to be taken more seriously within global policy frameworks based on adopting a One Health approach. The research is supported by a systematic analysis of the national action plans for addressing AMR published by the World Health Organisation (WHO). Results: We determine that political leaders need to do more to promote the problem of AMR and that global health institutions need to invest more energy in thinking about how AMR is governed as part of an already busy global health security agenda. This includes b...

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Research paper thumbnail of Enhancement of NAPL bioavailability by induction of cell-surface hydrophobicity in Exiguobacterium aurantiacum and Burkholderia cepacia

Induction of cell surface hydrophobicity in bacterial cultures can facilitate the direct interfac... more Induction of cell surface hydrophobicity in bacterial cultures can facilitate the direct interfacial uptake of non-aqueous phase liquids (NAPLs). This study explores bioavailability of NAPLs for Exiguobacterium aurantiacum and Burkholderia cepacia isolated from oil-contaminated soil and sediments. Surface tension measurements and emulsification activity tests did not provide evidence for release of extracellular biosurfactants/bioemulsifiers. Contact angle measurement on cell layers and bacterial adhesion to hydrocarbon (BATH) assay was conducted for determining the cell surface hydrophobicity. While the surfaces of cultures grown on soluble substrate, dextrose, were not hydrophobic, higher water contact angle and greater adherence to n-hexadecane/diesel revealed the highly hydrophobic nature of the cell surfaces for cultures grown on NAPLs (n-hexadecane and diesel), thus providing evidence for induction in cell surface hydrophobicity. Positive results in the carbocyanine assay indi...

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Research paper thumbnail of Defatted algal biomass as a non-conventional low-cost adsorbent: Surface characterization and methylene blue adsorption characteristics

Bioresource Technology, May 1, 2015

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Research paper thumbnail of Sorption of arsenic onto Vindhyan shales: Role of pyrite and organic carbon

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Research paper thumbnail of Impact of background water quality on disinfection performance and silver release of immobilized silver nanoparticles: Modeling disinfection kinetics, bactericidal mechanism and aggregation behavior

Chemical Engineering Journal, Sep 1, 2019

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Research paper thumbnail of Photocatalytic action of silver-titanium dioxide nanocomposite against pathogenic bacteria

Centre for Environmental Science and Engineering, Department of Bioscience and Bioengineering, In... more Centre for Environmental Science and Engineering, Department of Bioscience and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400 076, India <em>E</em>-<em>mail</em> : sbharti05@iitb.ac.in, mukherji@iitb.ac.in, mitras@iitb.ac.in <em>Manuscript received 15 November 2017, accepted 26 February 2018</em> <strong>Various waterborne disease outbreaks have been reported even after disinfection with conventional techniques due to development of resistance in microorganism. Moreover, generation of carcinogenic disin­fection by-products (DBPs) poses additional problems. This has prompted an exploration of alternative anti­microbial agents for disinfection of water. Over the last few decades, photocatalysis has been widely applied for degradation of various pollutants and inactivation of waterborne microbial pathogens. The present study was focused on the synthesis and characterization of Ag-TiO<sub>2</sub> nanocomposi...

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Research paper thumbnail of Screening of mineral media components for enhancing carbazole degradation by Pseudomonas aeruginosa RS1 using Plackett-Burman design

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Research paper thumbnail of Challenges in Detection of Antibiotics in Wastewater Matrix

Energy, Environment, and Sustainability, 2017

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Research paper thumbnail of Antiviral application of colloidal and immobilized silver nanoparticles

Nanotechnology, 2021

This study explored the application of colloidal and immobilized silver nanoparticles (AgNPs) for... more This study explored the application of colloidal and immobilized silver nanoparticles (AgNPs) for inactivation of bacteriophages. Coliphages that are commonly used as indicators for enteric viruses, were used in this study. Colloidal AgNPs were synthesized via a chemical reduction approach using sodium borohydride as reducing agent and trisodium citrate as stabilizing agent. AgNP-immobilized glass substrate was prepared by immobilizing AgNPs on amine-functionalized glass substrate by post-immobilization method. The AgNP-immobilized glass substrate was also tested so as to minimize the release of AgNPs in the treated water. The characterization of AgNPs and the AgNP-immobilized glass surface was done using field emission gun-transmission electron microscopy and scanning electron microscopy. Studies conducted with varying concentrations of colloidal AgNPs displayed good antiviral activity for MS2 and T4 bacteriophage. Colloidal AgNPs at a dose of 60 μg ml−1 could completely inactivate...

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Research paper thumbnail of Surveillance and seasonal correlation of Rotavirus A with coliphages and coliforms in two sewage impacted lakes in highly urbanized regions of western India

Environmental Science: Water Research & Technology, 2021

Group A Rotavirus (RVA), an enteric virus, is a major cause of gastroenteric disease and it is kn... more Group A Rotavirus (RVA), an enteric virus, is a major cause of gastroenteric disease and it is known to cause mortality among children, and infants. The applicability of coliforms and...

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Research paper thumbnail of Elucidation of substrate interaction effects in multicomponent systems containing 3-ring homocyclic and heterocyclic polynuclear aromatic hydrocarbons

Environmental Science: Processes & Impacts, 2021

This paper for the first time investigates substrate interactions during bacterial degradation of... more This paper for the first time investigates substrate interactions during bacterial degradation of carbazole, fluorene, and dibenzothiophene mixtures.

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Research paper thumbnail of Seasonal variation in fluorescence characteristics of dissolved organic matter in wastewater and identification of proteins through HRLC-MS/MS

Journal of Hazardous Materials, 2021

In the present study, wastewater samples acquired from five wastewater treatment plants (WWTPs), ... more In the present study, wastewater samples acquired from five wastewater treatment plants (WWTPs), located in western India were characterized using fluorescence spectroscopy, and resin-based fractionation was conducted to fractionate DOM into hydrophobic and hydrophilic base, acid, and neutral fractions. Among several fractions, the hydrophilic acid (HIA) and hydrophilic neutral (HIN) fractions were present in higher abundance (more than 50% of DOC) compared to the hydrophilic base (HIB) fraction in both influent and effluent wastewater stream obtained from WWTPs. Tryptophan-like and tyrosine-like substances were also abundant in the influent and effluent stream of WWTPs. Further, LC-MS/MS analysis could identify 235 and 288 DOM proteins in the influent and effluent stream of WWTP-1, respectively. These proteins revealed varying percentage of tryptophan and tyrosine residues. The tryptophan residues primarily contributed to protein-like fluorescence in wastewater. The proteins were further classified based on their role in biological processes, location in the cell, and molecular function. Among several proteins, Alzheimer's and Huntington disease biomarkers were identified at WWTP-1. Their presence in the surface water can serve as an early warning system for wastewater-based epidemiology.

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Research paper thumbnail of Evanescent Wave Optical Fiber Sensors Using Enzymatic Hydrolysis on Nanostructured Polyaniline for Detection of β-Lactam Antibiotics in Food and Environment

Analytical Chemistry, 2021

β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infect... more β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infection therapy. Consistent unintended exposure to these antibiotics via food and water is known to promote antibiotic-resistant bacterial pathogenesis with high morbidity and mortality in humans. An optical enzymatic biosensor for rapid and point-of-use detection of these antibiotics in food and water has been developed and tested. Enzymatic hydrolysis of β-lactams, on the electroactive polyaniline nanofibers, altered the polymeric backbone of the nanofibers, from emeraldine base form to emeraldine salt, which was measured as an increase in evanescent wave absorbance at 435 nm. The sensors were calibrated by spiking antibiotic-free milk with ceftazidime (as a model β-lactam analyte) in a linear range of 0.36-3600 nM (R2 = 0.98). The calibration was further validated for packaged milk, local cow milk, and buffalo milk. A similar calibration was devised for chicken meat samples in a linear range of 9-1800 nM (R2 = 0.982) and tap water in a linear range of 0.18-180 nM (R2 = 0.99). Interestingly, it was possible to use the same calibration for the determination of other β-lactam antibiotics (ampicillin, amoxicillin, and cefotaxime), which reflects the usefulness of the sensor for wide-scale deployment. The sensor performance was validated with a wastewater sample, from a wastewater treatment plant (WWTP), qualitatively analyzed by high-resolution liquid chromatography coupled with mass spectroscopy for detection of β-lactams. The sensor scheme developed and tested is of grassroot relevance as a quick solution for measurement of β-lactam residues in food and environment.

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Research paper thumbnail of The novel SARS-CoV-2 pandemic: Possible environmental transmission, detection, persistence and fate during wastewater and water treatment

Science of The Total Environment, 2021

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Research paper thumbnail of Characterization, phylogenetic distribution and evolutionary trajectories of diverse hydrocarbon degrading microorganisms isolated from refinery sludge

3 Biotech, 2018

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Research paper thumbnail of Characterization, phylogenetic distribution and evolutionary trajectories of diverse hydrocarbon degrading microorganisms isolated from refinery sludge

3 Biotech, 2018

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Research paper thumbnail of Impact of bioremediation strategies on slurry phase treatment of aged oily sludge from a refinery

Journal of Environmental Management, 2019

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Research paper thumbnail of Optimization of media composition for enhancing carbazole degradation by Pseudomonas aeruginosa RS1

Journal of Environmental Chemical Engineering, 2018

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Research paper thumbnail of Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Routledge Open Research

Background: This paper examines the suitability of extant governance frameworks at an internation... more Background: This paper examines the suitability of extant governance frameworks at an international level for addressing antimicrobial resistance (AMR), which is a creeping crisis for global health security. Methods: Our study begins by evaluating the place of antimicrobial resistance (AMR) within United Nations (UN) Sustainable Development Goals (SDG) targets and indicators. This is followed by a discussion of the global health security agenda (GHSA). We examine how AMR needs to be taken more seriously within global policy frameworks based on adopting a One Health approach. The research is supported by a systematic analysis of the national action plans for addressing AMR published by the World Health Organisation (WHO). Results: We determine that political leaders need to do more to promote the problem of AMR and that global health institutions need to invest more energy in thinking about how AMR is governed as part of an already busy global health security agenda. This includes b...

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Enhancement of NAPL bioavailability by induction of cell-surface hydrophobicity in Exiguobacterium aurantiacum and Burkholderia cepacia

Induction of cell surface hydrophobicity in bacterial cultures can facilitate the direct interfac... more Induction of cell surface hydrophobicity in bacterial cultures can facilitate the direct interfacial uptake of non-aqueous phase liquids (NAPLs). This study explores bioavailability of NAPLs for Exiguobacterium aurantiacum and Burkholderia cepacia isolated from oil-contaminated soil and sediments. Surface tension measurements and emulsification activity tests did not provide evidence for release of extracellular biosurfactants/bioemulsifiers. Contact angle measurement on cell layers and bacterial adhesion to hydrocarbon (BATH) assay was conducted for determining the cell surface hydrophobicity. While the surfaces of cultures grown on soluble substrate, dextrose, were not hydrophobic, higher water contact angle and greater adherence to n-hexadecane/diesel revealed the highly hydrophobic nature of the cell surfaces for cultures grown on NAPLs (n-hexadecane and diesel), thus providing evidence for induction in cell surface hydrophobicity. Positive results in the carbocyanine assay indi...

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Research paper thumbnail of Defatted algal biomass as a non-conventional low-cost adsorbent: Surface characterization and methylene blue adsorption characteristics

Bioresource Technology, May 1, 2015

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Research paper thumbnail of Sorption of arsenic onto Vindhyan shales: Role of pyrite and organic carbon

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Impact of background water quality on disinfection performance and silver release of immobilized silver nanoparticles: Modeling disinfection kinetics, bactericidal mechanism and aggregation behavior

Chemical Engineering Journal, Sep 1, 2019

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Photocatalytic action of silver-titanium dioxide nanocomposite against pathogenic bacteria

Centre for Environmental Science and Engineering, Department of Bioscience and Bioengineering, In... more Centre for Environmental Science and Engineering, Department of Bioscience and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai-400 076, India <em>E</em>-<em>mail</em> : sbharti05@iitb.ac.in, mukherji@iitb.ac.in, mitras@iitb.ac.in <em>Manuscript received 15 November 2017, accepted 26 February 2018</em> <strong>Various waterborne disease outbreaks have been reported even after disinfection with conventional techniques due to development of resistance in microorganism. Moreover, generation of carcinogenic disin­fection by-products (DBPs) poses additional problems. This has prompted an exploration of alternative anti­microbial agents for disinfection of water. Over the last few decades, photocatalysis has been widely applied for degradation of various pollutants and inactivation of waterborne microbial pathogens. The present study was focused on the synthesis and characterization of Ag-TiO<sub>2</sub> nanocomposi...

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Research paper thumbnail of Screening of mineral media components for enhancing carbazole degradation by Pseudomonas aeruginosa RS1 using Plackett-Burman design

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Challenges in Detection of Antibiotics in Wastewater Matrix

Energy, Environment, and Sustainability, 2017

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Antiviral application of colloidal and immobilized silver nanoparticles

Nanotechnology, 2021

This study explored the application of colloidal and immobilized silver nanoparticles (AgNPs) for... more This study explored the application of colloidal and immobilized silver nanoparticles (AgNPs) for inactivation of bacteriophages. Coliphages that are commonly used as indicators for enteric viruses, were used in this study. Colloidal AgNPs were synthesized via a chemical reduction approach using sodium borohydride as reducing agent and trisodium citrate as stabilizing agent. AgNP-immobilized glass substrate was prepared by immobilizing AgNPs on amine-functionalized glass substrate by post-immobilization method. The AgNP-immobilized glass substrate was also tested so as to minimize the release of AgNPs in the treated water. The characterization of AgNPs and the AgNP-immobilized glass surface was done using field emission gun-transmission electron microscopy and scanning electron microscopy. Studies conducted with varying concentrations of colloidal AgNPs displayed good antiviral activity for MS2 and T4 bacteriophage. Colloidal AgNPs at a dose of 60 μg ml−1 could completely inactivate...

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Surveillance and seasonal correlation of Rotavirus A with coliphages and coliforms in two sewage impacted lakes in highly urbanized regions of western India

Environmental Science: Water Research & Technology, 2021

Group A Rotavirus (RVA), an enteric virus, is a major cause of gastroenteric disease and it is kn... more Group A Rotavirus (RVA), an enteric virus, is a major cause of gastroenteric disease and it is known to cause mortality among children, and infants. The applicability of coliforms and...

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Elucidation of substrate interaction effects in multicomponent systems containing 3-ring homocyclic and heterocyclic polynuclear aromatic hydrocarbons

Environmental Science: Processes & Impacts, 2021

This paper for the first time investigates substrate interactions during bacterial degradation of... more This paper for the first time investigates substrate interactions during bacterial degradation of carbazole, fluorene, and dibenzothiophene mixtures.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Seasonal variation in fluorescence characteristics of dissolved organic matter in wastewater and identification of proteins through HRLC-MS/MS

Journal of Hazardous Materials, 2021

In the present study, wastewater samples acquired from five wastewater treatment plants (WWTPs), ... more In the present study, wastewater samples acquired from five wastewater treatment plants (WWTPs), located in western India were characterized using fluorescence spectroscopy, and resin-based fractionation was conducted to fractionate DOM into hydrophobic and hydrophilic base, acid, and neutral fractions. Among several fractions, the hydrophilic acid (HIA) and hydrophilic neutral (HIN) fractions were present in higher abundance (more than 50% of DOC) compared to the hydrophilic base (HIB) fraction in both influent and effluent wastewater stream obtained from WWTPs. Tryptophan-like and tyrosine-like substances were also abundant in the influent and effluent stream of WWTPs. Further, LC-MS/MS analysis could identify 235 and 288 DOM proteins in the influent and effluent stream of WWTP-1, respectively. These proteins revealed varying percentage of tryptophan and tyrosine residues. The tryptophan residues primarily contributed to protein-like fluorescence in wastewater. The proteins were further classified based on their role in biological processes, location in the cell, and molecular function. Among several proteins, Alzheimer's and Huntington disease biomarkers were identified at WWTP-1. Their presence in the surface water can serve as an early warning system for wastewater-based epidemiology.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Evanescent Wave Optical Fiber Sensors Using Enzymatic Hydrolysis on Nanostructured Polyaniline for Detection of β-Lactam Antibiotics in Food and Environment

Analytical Chemistry, 2021

β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infect... more β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infection therapy. Consistent unintended exposure to these antibiotics via food and water is known to promote antibiotic-resistant bacterial pathogenesis with high morbidity and mortality in humans. An optical enzymatic biosensor for rapid and point-of-use detection of these antibiotics in food and water has been developed and tested. Enzymatic hydrolysis of β-lactams, on the electroactive polyaniline nanofibers, altered the polymeric backbone of the nanofibers, from emeraldine base form to emeraldine salt, which was measured as an increase in evanescent wave absorbance at 435 nm. The sensors were calibrated by spiking antibiotic-free milk with ceftazidime (as a model β-lactam analyte) in a linear range of 0.36-3600 nM (R2 = 0.98). The calibration was further validated for packaged milk, local cow milk, and buffalo milk. A similar calibration was devised for chicken meat samples in a linear range of 9-1800 nM (R2 = 0.982) and tap water in a linear range of 0.18-180 nM (R2 = 0.99). Interestingly, it was possible to use the same calibration for the determination of other β-lactam antibiotics (ampicillin, amoxicillin, and cefotaxime), which reflects the usefulness of the sensor for wide-scale deployment. The sensor performance was validated with a wastewater sample, from a wastewater treatment plant (WWTP), qualitatively analyzed by high-resolution liquid chromatography coupled with mass spectroscopy for detection of β-lactams. The sensor scheme developed and tested is of grassroot relevance as a quick solution for measurement of β-lactam residues in food and environment.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of The novel SARS-CoV-2 pandemic: Possible environmental transmission, detection, persistence and fate during wastewater and water treatment

Science of The Total Environment, 2021

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Characterization, phylogenetic distribution and evolutionary trajectories of diverse hydrocarbon degrading microorganisms isolated from refinery sludge

3 Biotech, 2018

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Characterization, phylogenetic distribution and evolutionary trajectories of diverse hydrocarbon degrading microorganisms isolated from refinery sludge

3 Biotech, 2018

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Impact of bioremediation strategies on slurry phase treatment of aged oily sludge from a refinery

Journal of Environmental Management, 2019

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Optimization of media composition for enhancing carbazole degradation by Pseudomonas aeruginosa RS1

Journal of Environmental Chemical Engineering, 2018

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Research paper thumbnail of Substrate interaction effects during pyrene biodegradation by Pseudomonas aeruginosa RS1

Journal of Environmental Chemical Engineering, 2017

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Research paper thumbnail of Selective Removal of Photocatalytically Active Anatase TiO 2 Phase from Mixed‐Phase TiO 2 ‐ZnO Nanocomposites: Impact on Physicochemical Properties and Photocatalytic Activity

ENERGY & ENVIRONMENTAL MATERIALS, 2020

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