Syed Sajid - Academia.edu (original) (raw)

Papers by Syed Sajid

Symbolic language is a basic requirement for poetry. Therefore, we can say that in every era, poe... more Symbolic language is a basic requirement for poetry. Therefore, we can say that in every era, poets have worked with symbolic language and will continue to do so. In such a way that every metaphor is a symbol. For he denotes something beyond himself more than the basic meaning he has formulatedSymbolism is one such way of representation. In which instead of directly mentioning emotions and thoughts, these concepts are described through indirect factors.For poets with symbolic thinking, describing the feelings of the inner world rather than the outside world is the basic basis of poetry. Therefore, he considered symbolic expression to be the first in both form and style. Thinking presented topics such as dreams, misery, the mysteriousness of thought, disorder, madness, and nervous tension as symbols. This article deals Symbolism in Mohsin Naqvi's Poetry

to improve the performance of a system is the best criteria for developing any communication syst... more to improve the performance of a system is the best criteria for developing any communication system. The work presented here targets increasing the speed & performance of the OFDMA (Orthogonal Frequency-Division Multiple Access) modulator and demodulator. This paper presents a high level implementation of a high performance DCT for OFDM Modulator and Demodulator, with fewer computational steps than some other transforms. The design has been coded in VHDL and put into Xilinx Spartan3 FPGAs. The developed OFDMA communication structure can then be targeted to the OFDMA based WiMAX and other wireless communication systems, for increasing their efficiency by utilizing FPGA based DCT algorithm.

Recent advances in drug delivery and formulation, Sep 24, 2021

Co-crystal is an attractive alternative and a new class of solid forms because that can be engine... more Co-crystal is an attractive alternative and a new class of solid forms because that can be engineered to have desired physicochemical properties. Co-crystals have gained considerable attention from the generic pharmaceutical industry after the USFDA released its finalized guidlines in the year 2018 on the regulatory classification of co-crystals. In this review, we discussed how co-crystals could be explored as a potential alternative solid form for the development of a generic product that meets the legal, regulatory, and bioequivalence requirements. In the contents, we discussed in detail concepts such as the selection of coformers, various ways of making co-crystals, the strategy of characterization to discriminate between co-crystal and salt, polymorphism in co-crystals, the aspects of intellectual property and, finally, the regulatory aspects of co-crystals.

Pakistan Journal of Medical and Health Sciences, Nov 30, 2022

Objective: To determine etiology, sensitivity and resistance pattern of urinary tract infection i... more Objective: To determine etiology, sensitivity and resistance pattern of urinary tract infection in pediatrics age group 0 to 16 years at tertiary care hospital. Methodology: It was a cross-sectional study conducted inPediatric department of Aga khan university hospital and its affiliated secondary care centers in Karachi and Hyderabad. All urine culture proven children aged 0-16 years were included in the study. Urine culture showed growth of single pathogen and pathogen had more 10,000 colonies. Urine samples were obtained by SPA, clean catch, urinary catheter. Pre-designed proforma was used to note down the etiology and resistance pattern of urinary tract infection. SPSS version 25 was used to analyse data. Results: Of 177 patients, 70.1 % were females and 29.9% were males. Most common organism was E.coli 71.2% (n=126) followed by Klebsiella pneumonia 16.9% (n=30). Proteus Mirabilis 6.8% (n=12), and Pseudomonas aeruginosa 5.1% (n=9). Most common organism E.coli was 78% and 72.7% sensitive to nitrofurantoin and amikacin respectively and 85.1%, 91.4% and 77.3% resistance to ceftriaxone, ciprofloxacin and ampicillin respectively. This study will help in choosing choice of antibiotic on empirical basis for better outcome in resources limited setting like in remote areas and reduced financial burden on community. Conclusion: E.coli was the most common bacterial isolates among children with UTI. Nitrofurantoin and Amikacin showed higher sensitivity against E.coli., while Ciprofloxacin, Ceftriaxone and Ampicillin showed high resistance against E.coli.

Global digital & print media review, Dec 30, 2022

This paper investigates the comparison of how Pakistani women are stereotypically portrayed in Pa... more This paper investigates the comparison of how Pakistani women are stereotypically portrayed in Pakistani dramas with how they actually fit into society. The research follows the mixed-method approach. In the media industry, the portrayal of women all around the globe has been a subject of stereotypical agendas. These motives are discussed, considered, and pondered over. This is not the case in Pakistan. The topic of basing conventional narratives is still a well-known culture. In order to support this claim, this paper looked into the discrepancies between how Pakistani women are typically portrayed in Pakistani dramas and where they fit into the community. With the current affairs in Pakistan, Pakistani women are taking a stand for themselves and their rights, be that as it may, dramas still ponder over them being victims of society. This delineated outline will probe over the representation of women in dramas compared to society; is this the proper characterization of women, or not?

International Journal of Economic and Environmental Geology

The late Cretaceous Kawagarh Formation has been investigated in terms of field observation, and p... more The late Cretaceous Kawagarh Formation has been investigated in terms of field observation, and petrographic analysis, to understand the petrography and its impact on the geotechnical properties. The Kawagarh Formation is well exposed among the upper Indus Basin, and has been studied by various workers in different aspects. Kawagarh Formation exposed in Kahi section of Nizampur Basin has been selected in this study to know the behavior of carbonate rocks for engineering purposes. Lithologically, this formation is composed of thick to medium bedded, highly fractured limestone, marls, and dolomitic limestone which has undertaken diagenetic alteration including dolomite, calcite veins, and stylolites. Followed by petrographic analysis which reveals that the Kawagarh limestone is mostly fossiliferous comprised of a large number of planktonic foraminifera fossils like Globotruncana Hilli and Globotruncana Linneana fossils. Furthermore, to know the impact of petrographic minerals on engin...

Pakistan Journal of Medical and Health Sciences

Objective: To determine the frequency of thrombocytopenia in neonates undergoing exchange transfu... more Objective: To determine the frequency of thrombocytopenia in neonates undergoing exchange transfusion of blood for severe neonatal jaundice. Methodology: Total 200 neonates fulfilling the selection criteria were included in the study from neonatology unit, The Madinah Teaching Hospital Faisalabad during Nov, 2020 to October 2022. An informed consent was taken from parents. Demographic information (name, age, gender, and contact) was obtained. Then all neonates underwent exchange transfusion under standard procedure. After exchange transfusion 3cc Blood sample was obtained with the help of a staff nurse by using butterfly needle and 5cc BD syringe under aseptic measures. Sample was sent to the laboratory of the hospital for platelet count. If platelet count was found below 100.000/dL, thrombocytopenia was labelled (platelet count in complete blood count is <100,000/dL assessed at the end of exchange transfusion). Results: In our study, the mean age of the patients was calculated a...

Tribology - Materials, Surfaces & Interfaces

Background:Necrotizingenterocolitis (NEC) is the one of the commonest gastrointestinalemergency a... more Background:Necrotizingenterocolitis (NEC) is the one of the commonest gastrointestinalemergency and leadingcause of mortality in preterm and very low birth babies (VLBW). Objective: This study was conducted to determine the incidence and outcome of necrotizing enterocolitis in very low birth weight babies during stay in hospital.

BACKGROUND: There is not much information regarding the prevalence of different renal diseases in... more BACKGROUND: There is not much information regarding the prevalence of different renal diseases in paediatric population in Pakistan due to lack of central data. A few studies have been previouslypublished from individual centres. This study reflects the different histology patternsof renal diseases in children in our centre. OBJECTIVES: To assess the indications for kidney biopsy and determine the different histology patterns of renal diseases in paediatric patients in our centre.

BACKGROUND: Acute respiratory infections as pneumonia are one of the leading causes of death in c... more BACKGROUND: Acute respiratory infections as pneumonia are one of the leading causes of death in children.

BACKGROUND: Valproic acid (VPA) is a commonly used antiepileptic drug in children as well as adul... more BACKGROUND: Valproic acid (VPA) is a commonly used antiepileptic drug in children as well as adult population. It is widely used as a first-line agent for patients with partial or generalized epilepsy. Thrombocytopenia is one of the common side effects associatedwith VPA therapy. OBJECTIVES: To find out the frequency of thrombocytopenia in epileptic children receiving valproate as monotherapy for more than 6 months, in

BACKGROUND: Acute Gastroenteritis (AGE) is the leading cause of death in third world countries. F... more BACKGROUND: Acute Gastroenteritis (AGE) is the leading cause of death in third world countries. Feeding practices, water source and malnutrition are the well recognized risk factors for gastroenteritis.

BACKGROUND: Renal biopsy is the gold standard in nephrology, not only for diagnosis of renal dise... more BACKGROUND: Renal biopsy is the gold standard in nephrology, not only for diagnosis of renal diseases but also defining the management, prognosis and outcome. OBJECTIVE: To assess the safety and efficacy of the renal biopsy as an outpatient basis procedure with same day admission and discharge. DESIGN: Observational study. MATERIALS AND METHODS: This study had been conducted at Nephrology Department, The Children's Hospital and The Institute of Child Health, Lahore form 15 January 2014 till 14 January 2015. Total of 169 paedaitric patients having kidney disease who underwent renal biopsy were included as their their admission day, discharge day, biopsy day and complications were taken in account as before procedure patients were screened for bleeding diathesis. After renal biopsy patients were monitored for any complication and patients who showed no complication and stable were discharged from hospital on same day of biopsy. RESULTS: Total of 169 patients included, 109(64.5%) w...

Annals of Clinical and Analytical Medicine, 2021

Aim: The study aims to assess the efficiency of deep machine learning (convolutional neural netwo... more Aim: The study aims to assess the efficiency of deep machine learning (convolutional neural network architecture) for the diagnosis of psammomatous meningioma by evaluating the digital pathology images. Materials and Methods: A total of three hundred and twenty (320) digital images have been acquired from the anonymized hematoxylin and eosin-stained slides, which included 161 images of Psammomatous Meningioma and 159 images of normal intracranial tissue. The dataset was divided into a train set, 80% of the entire data, and 20% into the test data set. ResNet-18 architecture (state of the art deep learning computer vision algorithms) is used to diagnose these cases. Results: A total of 161 images of psammomatous meningioma and 159 images of normal tissue are used; 80% of the collected data was used for training, where 20% for testing purposes. Using deep learning, we achieved 98.79 F1-Score and 98.4% accuracy. Discussion: The advancement in the field of artificial intelligence has opened a lot of new channels and generated new opportunities to develop computer-aided diagnostic systems. The applications of machine learning have revealed promising results for the histopathological evaluation of neoplastic lesions. In the present study, the excellent diagnostic accuracy (98.4 %) has been achieved with the convolutional neural network architecture. There was an F1-score of 98.79 for the diagnosis of psammomatous meningioma in the present series. The studies conducted for the diagnosis of breast cancer metastasis, lung carcinoma, prostatic malignant tumors, and basal cell carcinoma also revealed excellent results. Convolutional neural network (CNN) architecture is emerging as a quite efficient deep machine learning tool for the analysis of the pathology images. This technology may be quite a valuable adjunct tool in diagnostic surgical pathology.

Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 2020

Metalworking fluids (MWFs) can greatly improve the machinability of materials and increase cuttin... more Metalworking fluids (MWFs) can greatly improve the machinability of materials and increase cutting tool life. There are a range of MWF products available on the market, however there are very few reliable low cost machining based fluid screening tests which can help select the most suitable candidate. This study developed a novel and rigorous single point milling (SPM) procedure carried out under controlled conditions, which would provide fluid performance differentiation for a range of typical aerospace alloys. The use of a single insert with a controlled geometry reduced machining variance and ensured performance repeatability. Tool life curves were used to determine optimum machining surface speeds for Inconel 718 (In718) of 80 m/min and Ti-6Al-4V (Ti64) of 160 m/min. Carrying out trials using five different cutting fluid products within a controlled tool life window clearly demonstrated that the SPM machining test was able to differentiate performance on both In718 and Ti64 mate...

SSRN Electronic Journal, 2020

COVID-19 pandemic has caused havoc worldwide. India is also going through a challenging situation... more COVID-19 pandemic has caused havoc worldwide. India is also going through a challenging situation as the number of infected/positive cases is increasing day by day. With strict preventive measures and restrictions by the Indian Government in the form of nationwide lockdown, the citizens are going through a range of psychological and emotion reactions, fear and uncertainty being one of them. This study was conducted with the aim of exploring the impact of Covid-19 and lockdown on the mental health of individuals. DASS-21 was used to assess Depression, Anxiety and Stress among 1000 respondents. Results suggest that there is a significant difference among Depression, Anxiety and Stress across age, gender and employment. Also, Depression was found to be high among the respondents of age range 15-35 years, Anxiety was found to be prevalent among those belonging to 21-25 years of age and Stress was found to be high in individuals of 21-25 years of age.

Annals of Clinical and Analytical Medicine, 2020

Aim: The current study aimed to identify the toxic effects of oral ingestion of different doses o... more Aim: The current study aimed to identify the toxic effects of oral ingestion of different doses of silver oxide nanoparticle, for 21 days, on the liver, kidney and muscle tissues of mice by histopathological examination. Materials and Methods: The nanoparticles of silver oxide (30-70 nm in diameter) were prepared by physical methods and administered orally to 3 experimental groups of BALB/c mice in the strength of 250, 375, and 500 mg/kg, respectively for 21 days. Liver, kidney, and muscle tissue specimens from control and nanoparticles exposed groups have been collected for histopathological evaluation. Results: The liver and kidney tissue of the mice fed with 500 mg/kg of silver nanoparticles revealed portal inflammation in the liver tissue and mild interstitial inflammation in the renal tissue. There is no histopathological evidence of any toxic effects in the other groups The muscle tissue from all experimental groups is unremarkable. Discussion: The dose, size of nanoparticles, duration, the route of exposure and limiting factors for nanoparticles induced toxic effects. Hence further studies with different variables regarding the nanoparticles exposure will be helpful for a better understanding of toxicity caused by nanoparticles.

Symbolic language is a basic requirement for poetry. Therefore, we can say that in every era, poe... more Symbolic language is a basic requirement for poetry. Therefore, we can say that in every era, poets have worked with symbolic language and will continue to do so. In such a way that every metaphor is a symbol. For he denotes something beyond himself more than the basic meaning he has formulatedSymbolism is one such way of representation. In which instead of directly mentioning emotions and thoughts, these concepts are described through indirect factors.For poets with symbolic thinking, describing the feelings of the inner world rather than the outside world is the basic basis of poetry. Therefore, he considered symbolic expression to be the first in both form and style. Thinking presented topics such as dreams, misery, the mysteriousness of thought, disorder, madness, and nervous tension as symbols. This article deals Symbolism in Mohsin Naqvi's Poetry

to improve the performance of a system is the best criteria for developing any communication syst... more to improve the performance of a system is the best criteria for developing any communication system. The work presented here targets increasing the speed & performance of the OFDMA (Orthogonal Frequency-Division Multiple Access) modulator and demodulator. This paper presents a high level implementation of a high performance DCT for OFDM Modulator and Demodulator, with fewer computational steps than some other transforms. The design has been coded in VHDL and put into Xilinx Spartan3 FPGAs. The developed OFDMA communication structure can then be targeted to the OFDMA based WiMAX and other wireless communication systems, for increasing their efficiency by utilizing FPGA based DCT algorithm.

Recent advances in drug delivery and formulation, Sep 24, 2021

Co-crystal is an attractive alternative and a new class of solid forms because that can be engine... more Co-crystal is an attractive alternative and a new class of solid forms because that can be engineered to have desired physicochemical properties. Co-crystals have gained considerable attention from the generic pharmaceutical industry after the USFDA released its finalized guidlines in the year 2018 on the regulatory classification of co-crystals. In this review, we discussed how co-crystals could be explored as a potential alternative solid form for the development of a generic product that meets the legal, regulatory, and bioequivalence requirements. In the contents, we discussed in detail concepts such as the selection of coformers, various ways of making co-crystals, the strategy of characterization to discriminate between co-crystal and salt, polymorphism in co-crystals, the aspects of intellectual property and, finally, the regulatory aspects of co-crystals.

Pakistan Journal of Medical and Health Sciences, Nov 30, 2022

Objective: To determine etiology, sensitivity and resistance pattern of urinary tract infection i... more Objective: To determine etiology, sensitivity and resistance pattern of urinary tract infection in pediatrics age group 0 to 16 years at tertiary care hospital. Methodology: It was a cross-sectional study conducted inPediatric department of Aga khan university hospital and its affiliated secondary care centers in Karachi and Hyderabad. All urine culture proven children aged 0-16 years were included in the study. Urine culture showed growth of single pathogen and pathogen had more 10,000 colonies. Urine samples were obtained by SPA, clean catch, urinary catheter. Pre-designed proforma was used to note down the etiology and resistance pattern of urinary tract infection. SPSS version 25 was used to analyse data. Results: Of 177 patients, 70.1 % were females and 29.9% were males. Most common organism was E.coli 71.2% (n=126) followed by Klebsiella pneumonia 16.9% (n=30). Proteus Mirabilis 6.8% (n=12), and Pseudomonas aeruginosa 5.1% (n=9). Most common organism E.coli was 78% and 72.7% sensitive to nitrofurantoin and amikacin respectively and 85.1%, 91.4% and 77.3% resistance to ceftriaxone, ciprofloxacin and ampicillin respectively. This study will help in choosing choice of antibiotic on empirical basis for better outcome in resources limited setting like in remote areas and reduced financial burden on community. Conclusion: E.coli was the most common bacterial isolates among children with UTI. Nitrofurantoin and Amikacin showed higher sensitivity against E.coli., while Ciprofloxacin, Ceftriaxone and Ampicillin showed high resistance against E.coli.

Global digital & print media review, Dec 30, 2022

This paper investigates the comparison of how Pakistani women are stereotypically portrayed in Pa... more This paper investigates the comparison of how Pakistani women are stereotypically portrayed in Pakistani dramas with how they actually fit into society. The research follows the mixed-method approach. In the media industry, the portrayal of women all around the globe has been a subject of stereotypical agendas. These motives are discussed, considered, and pondered over. This is not the case in Pakistan. The topic of basing conventional narratives is still a well-known culture. In order to support this claim, this paper looked into the discrepancies between how Pakistani women are typically portrayed in Pakistani dramas and where they fit into the community. With the current affairs in Pakistan, Pakistani women are taking a stand for themselves and their rights, be that as it may, dramas still ponder over them being victims of society. This delineated outline will probe over the representation of women in dramas compared to society; is this the proper characterization of women, or not?

International Journal of Economic and Environmental Geology

The late Cretaceous Kawagarh Formation has been investigated in terms of field observation, and p... more The late Cretaceous Kawagarh Formation has been investigated in terms of field observation, and petrographic analysis, to understand the petrography and its impact on the geotechnical properties. The Kawagarh Formation is well exposed among the upper Indus Basin, and has been studied by various workers in different aspects. Kawagarh Formation exposed in Kahi section of Nizampur Basin has been selected in this study to know the behavior of carbonate rocks for engineering purposes. Lithologically, this formation is composed of thick to medium bedded, highly fractured limestone, marls, and dolomitic limestone which has undertaken diagenetic alteration including dolomite, calcite veins, and stylolites. Followed by petrographic analysis which reveals that the Kawagarh limestone is mostly fossiliferous comprised of a large number of planktonic foraminifera fossils like Globotruncana Hilli and Globotruncana Linneana fossils. Furthermore, to know the impact of petrographic minerals on engin...

Pakistan Journal of Medical and Health Sciences

Objective: To determine the frequency of thrombocytopenia in neonates undergoing exchange transfu... more Objective: To determine the frequency of thrombocytopenia in neonates undergoing exchange transfusion of blood for severe neonatal jaundice. Methodology: Total 200 neonates fulfilling the selection criteria were included in the study from neonatology unit, The Madinah Teaching Hospital Faisalabad during Nov, 2020 to October 2022. An informed consent was taken from parents. Demographic information (name, age, gender, and contact) was obtained. Then all neonates underwent exchange transfusion under standard procedure. After exchange transfusion 3cc Blood sample was obtained with the help of a staff nurse by using butterfly needle and 5cc BD syringe under aseptic measures. Sample was sent to the laboratory of the hospital for platelet count. If platelet count was found below 100.000/dL, thrombocytopenia was labelled (platelet count in complete blood count is <100,000/dL assessed at the end of exchange transfusion). Results: In our study, the mean age of the patients was calculated a...

Tribology - Materials, Surfaces & Interfaces

Background:Necrotizingenterocolitis (NEC) is the one of the commonest gastrointestinalemergency a... more Background:Necrotizingenterocolitis (NEC) is the one of the commonest gastrointestinalemergency and leadingcause of mortality in preterm and very low birth babies (VLBW). Objective: This study was conducted to determine the incidence and outcome of necrotizing enterocolitis in very low birth weight babies during stay in hospital.

BACKGROUND: There is not much information regarding the prevalence of different renal diseases in... more BACKGROUND: There is not much information regarding the prevalence of different renal diseases in paediatric population in Pakistan due to lack of central data. A few studies have been previouslypublished from individual centres. This study reflects the different histology patternsof renal diseases in children in our centre. OBJECTIVES: To assess the indications for kidney biopsy and determine the different histology patterns of renal diseases in paediatric patients in our centre.

BACKGROUND: Acute respiratory infections as pneumonia are one of the leading causes of death in c... more BACKGROUND: Acute respiratory infections as pneumonia are one of the leading causes of death in children.

BACKGROUND: Valproic acid (VPA) is a commonly used antiepileptic drug in children as well as adul... more BACKGROUND: Valproic acid (VPA) is a commonly used antiepileptic drug in children as well as adult population. It is widely used as a first-line agent for patients with partial or generalized epilepsy. Thrombocytopenia is one of the common side effects associatedwith VPA therapy. OBJECTIVES: To find out the frequency of thrombocytopenia in epileptic children receiving valproate as monotherapy for more than 6 months, in

BACKGROUND: Acute Gastroenteritis (AGE) is the leading cause of death in third world countries. F... more BACKGROUND: Acute Gastroenteritis (AGE) is the leading cause of death in third world countries. Feeding practices, water source and malnutrition are the well recognized risk factors for gastroenteritis.

BACKGROUND: Renal biopsy is the gold standard in nephrology, not only for diagnosis of renal dise... more BACKGROUND: Renal biopsy is the gold standard in nephrology, not only for diagnosis of renal diseases but also defining the management, prognosis and outcome. OBJECTIVE: To assess the safety and efficacy of the renal biopsy as an outpatient basis procedure with same day admission and discharge. DESIGN: Observational study. MATERIALS AND METHODS: This study had been conducted at Nephrology Department, The Children's Hospital and The Institute of Child Health, Lahore form 15 January 2014 till 14 January 2015. Total of 169 paedaitric patients having kidney disease who underwent renal biopsy were included as their their admission day, discharge day, biopsy day and complications were taken in account as before procedure patients were screened for bleeding diathesis. After renal biopsy patients were monitored for any complication and patients who showed no complication and stable were discharged from hospital on same day of biopsy. RESULTS: Total of 169 patients included, 109(64.5%) w...

Annals of Clinical and Analytical Medicine, 2021

Aim: The study aims to assess the efficiency of deep machine learning (convolutional neural netwo... more Aim: The study aims to assess the efficiency of deep machine learning (convolutional neural network architecture) for the diagnosis of psammomatous meningioma by evaluating the digital pathology images. Materials and Methods: A total of three hundred and twenty (320) digital images have been acquired from the anonymized hematoxylin and eosin-stained slides, which included 161 images of Psammomatous Meningioma and 159 images of normal intracranial tissue. The dataset was divided into a train set, 80% of the entire data, and 20% into the test data set. ResNet-18 architecture (state of the art deep learning computer vision algorithms) is used to diagnose these cases. Results: A total of 161 images of psammomatous meningioma and 159 images of normal tissue are used; 80% of the collected data was used for training, where 20% for testing purposes. Using deep learning, we achieved 98.79 F1-Score and 98.4% accuracy. Discussion: The advancement in the field of artificial intelligence has opened a lot of new channels and generated new opportunities to develop computer-aided diagnostic systems. The applications of machine learning have revealed promising results for the histopathological evaluation of neoplastic lesions. In the present study, the excellent diagnostic accuracy (98.4 %) has been achieved with the convolutional neural network architecture. There was an F1-score of 98.79 for the diagnosis of psammomatous meningioma in the present series. The studies conducted for the diagnosis of breast cancer metastasis, lung carcinoma, prostatic malignant tumors, and basal cell carcinoma also revealed excellent results. Convolutional neural network (CNN) architecture is emerging as a quite efficient deep machine learning tool for the analysis of the pathology images. This technology may be quite a valuable adjunct tool in diagnostic surgical pathology.

Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 2020

Metalworking fluids (MWFs) can greatly improve the machinability of materials and increase cuttin... more Metalworking fluids (MWFs) can greatly improve the machinability of materials and increase cutting tool life. There are a range of MWF products available on the market, however there are very few reliable low cost machining based fluid screening tests which can help select the most suitable candidate. This study developed a novel and rigorous single point milling (SPM) procedure carried out under controlled conditions, which would provide fluid performance differentiation for a range of typical aerospace alloys. The use of a single insert with a controlled geometry reduced machining variance and ensured performance repeatability. Tool life curves were used to determine optimum machining surface speeds for Inconel 718 (In718) of 80 m/min and Ti-6Al-4V (Ti64) of 160 m/min. Carrying out trials using five different cutting fluid products within a controlled tool life window clearly demonstrated that the SPM machining test was able to differentiate performance on both In718 and Ti64 mate...

SSRN Electronic Journal, 2020

COVID-19 pandemic has caused havoc worldwide. India is also going through a challenging situation... more COVID-19 pandemic has caused havoc worldwide. India is also going through a challenging situation as the number of infected/positive cases is increasing day by day. With strict preventive measures and restrictions by the Indian Government in the form of nationwide lockdown, the citizens are going through a range of psychological and emotion reactions, fear and uncertainty being one of them. This study was conducted with the aim of exploring the impact of Covid-19 and lockdown on the mental health of individuals. DASS-21 was used to assess Depression, Anxiety and Stress among 1000 respondents. Results suggest that there is a significant difference among Depression, Anxiety and Stress across age, gender and employment. Also, Depression was found to be high among the respondents of age range 15-35 years, Anxiety was found to be prevalent among those belonging to 21-25 years of age and Stress was found to be high in individuals of 21-25 years of age.

Annals of Clinical and Analytical Medicine, 2020

Aim: The current study aimed to identify the toxic effects of oral ingestion of different doses o... more Aim: The current study aimed to identify the toxic effects of oral ingestion of different doses of silver oxide nanoparticle, for 21 days, on the liver, kidney and muscle tissues of mice by histopathological examination. Materials and Methods: The nanoparticles of silver oxide (30-70 nm in diameter) were prepared by physical methods and administered orally to 3 experimental groups of BALB/c mice in the strength of 250, 375, and 500 mg/kg, respectively for 21 days. Liver, kidney, and muscle tissue specimens from control and nanoparticles exposed groups have been collected for histopathological evaluation. Results: The liver and kidney tissue of the mice fed with 500 mg/kg of silver nanoparticles revealed portal inflammation in the liver tissue and mild interstitial inflammation in the renal tissue. There is no histopathological evidence of any toxic effects in the other groups The muscle tissue from all experimental groups is unremarkable. Discussion: The dose, size of nanoparticles, duration, the route of exposure and limiting factors for nanoparticles induced toxic effects. Hence further studies with different variables regarding the nanoparticles exposure will be helpful for a better understanding of toxicity caused by nanoparticles.