Técia Maria de Oliveira Maranhão (original) (raw)

Papers by Técia Maria de Oliveira Maranhão

Research paper thumbnail of Psychophysiological responses of women with polycystic ovary syndrome during sessions of high-intensity interval training

Human Movement, 2022

Purpose. The study described psychophysiological responses (perceived exertion, affective respons... more Purpose. The study described psychophysiological responses (perceived exertion, affective response) of women with polycystic ovary syndrome (PcOS) throughout 10 sessions of high-intensity interval training (HIIT). Methods. Overall, 12 physically inactive women with PcOS (age: 26.2 ± 4.1 years; body mass index: 28.5 ± 6.3 kg/m 2) performed 10 running HIIT sessions of 50 min [10 × 1-min intervals, 90% of maximal heat rate (HRmax); 3-min active recovery periods, 70% HRmax], including 5-min warm-up and cool-down, with 48-hour intervals. HRmax, rating of perceived exertion (RPE, Borg cR10 scale), and affective responses (Feeling Scale) were assessed in the last 10 s of each interval and recovery period. Each session responses were grouped into session parts (beginning, 1-3; middle, 4-7; end, 8-10) for intervals and recovery periods separately. The generalized estimating equation model served to compare %HRmax, RPE, and affective valence between session parts. Results. The intensities of intervals (p < 0.001) and recovery (p < 0.001) increased from session beginning to end, as did RPE of intervals (p < 0.001) and recovery (p < 0.001). Interval affective responses were lower at end compared with beginning (p < 0.040). HIIT intensity (%HRmax) presented a small coefficient of variation (cV, ca. 3%); RPE exhibited medium cV (ca. 20%) between 10 HIIT sessions. Conclusions. Psychophysiological responses of physically inactive PcOS women to running HIIT demonstrate positive affective valence at the beginning of HIIT sessions. As the session progresses, affective valence decreases to neutral and RPE increases.

Research paper thumbnail of Considerações sobre a gestação na vigência do uso de metformina, em portadoras da síndrome dos ovários policísticos; Considerations about pregnancy following …

Reprod. clim, 2003

Resumo: O uso da metformina, um agente hipoglicemiante oral que aumenta a sensibilidade à insulin... more Resumo: O uso da metformina, um agente hipoglicemiante oral que aumenta a sensibilidade à insulina, tem sido amplamente difundido entre os ginecologistas na abordagem da síndrome dos ovários policísticos (SOP). Enquanto muitos benefícios ...

Research paper thumbnail of Serum leptin levels in healthy postmenopausal women receiving raloxifene

Research paper thumbnail of Sí­ndrome dos ovários policí­sticos e sí­ndrome metabólica: uma associação significativa com implicações clí­nicas

1Aluno bolsista PPq/UFRN; 2Colaboradora, Maternidade Escola Januário Cicco; 3Colaboradora, Labora... more 1Aluno bolsista PPq/UFRN; 2Colaboradora, Maternidade Escola Januário Cicco; 3Colaboradora, Laboratório Integrado de Análises Clínicas da Faculdade de Farmácia; 4Professora Orientadora, Departamento de Tocoginecologia do Centro de Ciências da Saúde; ...

Research paper thumbnail of Resistência à insulina em mulheres com síndrome dos ovários policísticos: relação com as variáveis antropométricas e bioquímicas

Revista Brasileira de Ginecologia e Obstetrícia, Feb 1, 2012

OBJETIVO: Analisar a prevalência de resistência à insulina de acordo com diferentes medidas antro... more OBJETIVO: Analisar a prevalência de resistência à insulina de acordo com diferentes medidas antropométricas e bioquímicas em mulheres com síndrome dos ovários policísticos. MÉTODOS: Foram analisadas, retrospectivamente, 189 pacientes com síndrome dos ovários policísticos. O diagnóstico de resistência à insulina foi obtido utilizando-se insulinemia, HOMA-IR, QUICKI, índice de sensibilidade à insulina e relação glicemia/insulina. Foram utilizados o índice de massa corpórea e o lipid accumulation product. Para análise dos resultados, aplicou-se a estatística descritiva, a ANOVA, o pós-teste de Tukey e a correlação de Pearson. RESULTADOS: As pacientes apresentaram média de idade de 24,9±5,2 e de índice de massa corpórea de 31,8±7,6. O percentual de pacientes obesas foi de 57,14%. Dentre os métodos de investigação de resistência à insulina, o índice de sensibilidade à insulina foi a técnica que mais detectou (56,4%) a presença de resistência à insulina nas mulheres com síndrome dos ovários policísticos. Em 87% das pacientes obesas, detectou-se a resistência à insulina. A relação glicemia/insulinemia de jejum e o índice de sensibilidade à insulina apresentaram correlação forte com o lipid accumulation product. CONCLUSÃO: A prevalência de resistência à insulina variou de acordo com o método utilizado e foi maior quanto maior o índice de massa corpórea. O lipid accumulation product também está relacionado à resistência à insulina.

Research paper thumbnail of Irregularidade do ciclo menstrual no menacme como marcador para fatores de risco cardiovasculares na pós-menopausa

Arquivos Brasileiros De Endocrinologia E Metabologia, Oct 1, 2006

Menstrual Cycle Irregularity as a Marker of Cardiovascular Risk Factors at Postmenopausal Years. ... more Menstrual Cycle Irregularity as a Marker of Cardiovascular Risk Factors at Postmenopausal Years. To evaluate the association between cardiovascular risk factors (CVRF) during postmenopausal years and previous menstrual irregularity during reproductive years, we performed a case-control study in 414 postmenopausal women (mean age 60.4 ± 5.5 years; BMI 25.3 ± 4.7 kg/m 2). The variables assessed were: menstrual cycle characteristics at age 20-35y (independent) and records of arterial hypertension, dyslipidemia, diabetes mellitus, and coronary heart disease (dependent). Statistical analysis used the chi-square test and logistic regression, adjusting for potential confounders for cardiovascular risk, with significance set at 5%. Women reporting previous menstrual irregularity were associated with increased risk for some CVRF [adjusted odds ratio (OR) 2.14; CI-95%= 1.02-4.48], when compared with those reporting regular menstrual cycles. Stratified analysis demonstrated significant associations of previous menstrual irregularity with: arterial hypertension [OR= 2.74; CI-95%= 1.39-5.41), hypercholesterolemia (OR= 2.32; CI-95%= 1.17-4.59), hypertriglyceridemia (OR= 2.09; CI-95%=1.10-4.33), and coronary angioplasty artigo original

Research paper thumbnail of Terapia de reposição hormonal na pós-menopausa: efeitos sobre o sistema hemostático e risco de trombose

Femina, 2003

página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Sá, Marcos Felipe Silva de. ex... more página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Sá, Marcos Felipe Silva de. experimental, Documentos relacionados. Id: 357946. Autor: Azevedo, George Dantas de; Franco, Rendrik França; Maranhão, Técia Maria de Oliveira; Sá, Marcos Felipe Silva de. ...

Research paper thumbnail of Macroprolactinemia: as vantagens do rastreamento na prática clínica

Revista Brasileira de Ginecologia e Obstetrícia, Jul 1, 2010

Fernanda vieira rodovalho-callegari 2 Maristela carbol patta 3 patrícia Margareth lizarelli 4 car... more Fernanda vieira rodovalho-callegari 2 Maristela carbol patta 3 patrícia Margareth lizarelli 4 carolina sales vieira 5 técia Maria oliveira Maranhão 6 Editorial A prolactina (PRL) é um hormônio hipofisário que circula em diferentes formas moleculares: "little" ou "small", monomérica, que é biologicamente ativa (Peso Molecular 23 kDa); "big" (PM 50-60 kDa); "big-big" (PM 150-170 kDa), também conhecida como macroprolactina, que é constituída pela molécula da PRL ligada a um complexo de IgG 1,2. No soro de indivíduos normais, a forma monomérica é a predominante (85-95%), enquanto a "big-big" PRL constitui a forma menos frequente (<1%) 3. A hiperprolactinemia é uma das alterações endócrinas mais comuns do eixo hipotálamohipofisário, acometendo 0,4% da população adulta e 9-17% das mulheres com distúrbios reprodutivos. Sua etiologia é variada e, excluindo-se as causas fisiológicas, o uso de algumas medicações e o hipotireoidismo, os tumores hipofisários secretores ou não de PRL representam a principal causa de hiperprolactinemia. As manifestações clínicas da hiperprolactinemia compreendem uma série de sintomas como os distúrbios menstruais, galactorreia, infertilidade, hirsutismo e alterações neurooftalmológicas, estas últimas quando a causa é um tumor de maiores proporções. A longo prazo, a hiperprolactinemia pode levar à osteoporose como consequência do hipoestrogenismo que se estabelece nessas pacientes. A associação desses sintomas e sinais com elevação dos níveis de PRL plasmática torna obrigatória, portanto, a investigação da etiologia com foco especial na detecção de um tumor hipofisário, principalmente os secretores de PRL, chamados prolactinomas, o que é feito sistematicamente através de exames de imagem como a Tomografia Computadorizada (TC) e a Ressonância Nuclear Magnética (RNM) 4 .

Research paper thumbnail of Pelvic floor muscle thickness in women with polycystic ovary syndrome

Clinical and Experimental Obstetrics & Gynecology, Dec 10, 2018

Objective: To evaluate pelvic floor muscle (PFM) thickness in women with polycystic ovary syndrom... more Objective: To evaluate pelvic floor muscle (PFM) thickness in women with polycystic ovary syndrome (PCOS) group and compare it to those with normal menstrual cycle (control group). Materials and Methods: Transperineal ultrasound examination was used to evaluate the thickness of the bilateral pelvic floor muscles Results: The mean age was 25.1 ± 2.1 and 24.2 ± 1.9 years in PCOS and control groups, respectively (p > 0.05). Body mass index averaged 22.5 ± 0.9 in the control group and 27.8 ± 2.6 in the PCOS group (p = 0.03). There was no difference between the thickness of the pelvic floor muscles (PCOS group: right 1.12 ± 0.5, left 1.0 ± 0.6 and control group: right 0.89 ± 0.6 and left 0.94 ± 0.4. Conclusions: There was no differences in pelvic floor muscle thickness identified by ultrasound. However, the PCOS group exhibited a tendency to greater thickness. This may be due to the state of hyperandrogenism or abdominal overload.

Research paper thumbnail of Breast changes in pregnancy and lactation observed by ultrasonography

Clinical and Experimental Obstetrics & Gynecology, 2019

Purpose of Investigation: To assess the ultrasound aspects of breasts and laser Doppler flow meas... more Purpose of Investigation: To assess the ultrasound aspects of breasts and laser Doppler flow measurements of the internal mammary arteries (IMA) in pregnant, lactating, and non-pregnant (control) women. Materials and Methods: A cross-sectional observation study of 102 women, divided into three groups: control (CG), third trimester (G3), and lactation group (LG). The study variables were skin, subcutaneous adipose tissue, fibroglandular tissue, retromammary adipose tissue thickness, duct diameter, and pulsatility (PI) and resistance indices (RI) of the internal mammary arteries. Statistical analysis calculated the means and standard deviations, using two models Multivariate Analysis of Variance (MANOVA) models to assess the effect of groups on the mean values found and adjusted ANOVA models for individual means. The Tukey-Kramer multiple comparisons test was used to analyze intergroup. Results: There was no intergroup age difference (mean = 27 ± 4.76 years). A significant difference was observed between the G3/LG and the CG in terms of skin (p = 0.001), fibroglandular tissue thickness, duct diameter, and laser Doppler flow measurements of the IMA (all three with p < 0.001) and subcutaneous adipose tissue (p = 0.045). Conclusion: This study showed alterations in skin, subcutaneous adipose tissue, fibroglandular tissue, and duct diameter measurements, with a difference between pregnant/lactating women and the non-pregnant controls.

Research paper thumbnail of Use of androgens at different stages of life: climacterium

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2022

• Female sexual dysfunction (FSD) includes hypoactive sexual desire disorders (HSDD) and sexual a... more • Female sexual dysfunction (FSD) includes hypoactive sexual desire disorders (HSDD) and sexual arousal, orgasm disorders and genito pelvic pain disorder, and vaginal penetration disorders. • Female sexual dysfunction affects around 45% of women, most of them postmenopausal. • The genitourinary menopause syndrome (GMS) includes signs and symptoms related to atrophy of the genital tract and predisposes to vaginal and/or urinary infections, in addition to interfering with the woman's sexual performance. • There is a decline in cognitive function in postmenopausal women, and estrogens and androgens appear to independently influence cognitive activity. • The characterization of postmenopausal androgen deficiency and the prescription of androgen therapy is still a controversial topic.

Research paper thumbnail of Use of androgens at different stages of life: reproductive period

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2021

Research paper thumbnail of The effect of exercise as an intervention for women with polycystic ovary syndrome

Medicine, 2020

Background: Polycystic ovary syndrome (PCOS) affects reproductive-aged women and is associated wi... more Background: Polycystic ovary syndrome (PCOS) affects reproductive-aged women and is associated with increased prevalence of serious clinical problems including: reproductive implications, metabolic dysfunction, and cardiovascular risk. Physical activity offers several health benefits for women with PCOS. The aim of this systematic review was to synthesize evidence on the effect of different types of exercise on reproductive function and body composition for women with PCOS. Methods: This was a systematic review and meta-analysis of randomized controlled trials (RCTs) following recommended review methods. We searched 6 databases: Cumulative Index of Nursing and Allied Health Literature; Embase; MEDLINE (via Ovid); PubMed; Sport Discus; and Web of Science; and we developed search strategies using a combination of Medical Subject Headings terms and text words related to exercise interventions for women with PCOS. There was no restriction on language or publication year. The search was ...

Research paper thumbnail of Clustering of risk factors for cardiometabolic diseases in low-income, female adolescents

Archives of endocrinology and metabolism, Jan 16, 2016

Objective To assess the prevalence and clustering patterns of cardiometabolic risk factors among ... more Objective To assess the prevalence and clustering patterns of cardiometabolic risk factors among low-income, female adolescents. Materials and methods Cross-sectional study involving 196 students of public schools (11-19 years old). The following risk factors were considered in the analysis: excess weight, central obesity, dyslipidemia, high blood pressure, and high fasting glucose. The ratio between observed and expected prevalence and its confidence interval were used to identify clustering of risk factors that exceeded expected prevalence in the population. Results The most prevalent risk factors were dyslipidemia (70.9%), and central obesity (39.8%), followed by excess weight (29.6%), and high blood pressure (12.8%). A total of 42.9% of adolescents had two or more risk factors, and 24% had three or more. Excess weight, central obesity, and dyslipidemia were common risk factors in the clustering patterns that showed higher-than-expected prevalence. Conclusions Clustering of risk ...

Research paper thumbnail of Is there a difference in the electromyographic activity of the pelvic floor muscles across the phases of the menstrual cycle?

Journal of Physical Therapy Science, 2015

To evaluate the electrical activity of the pelvic floor muscle in women during the follicular, ov... more To evaluate the electrical activity of the pelvic floor muscle in women during the follicular, ovulatory, and luteal phases of the menstrual cycle and its correlation with estradiol and total testosterone levels. [Subjects and Methods] This cross-sectional study involved 30 women with ovulatory menstrual cycles. Total testosterone and estradiol levels were measured and the muscle tone and maximum voluntary contraction of the pelvic floor muscles were evaluated using surface electromyography. [Results] Muscle tone was significantly lower during the follicular (21.1±3.3 μV) and ovulatory (27.1±5.9 μV) phases than the luteal phase (30.4±4.1 μV). The maximum voluntary contraction was not different across phases. The estradiol level on the 7th day of the menstrual cycle showed a strong positive correlation with muscle tone and maximum voluntary contraction, and the testosterone level was positively correlated with muscle tone on the 21st day. [Conclusion] Women have better muscle tone during the luteal phase. The muscle tone and maximum voluntary contraction were strongly correlated with the estradiol level on the 7th day, and the muscle tone was correlated with the testosterone level on the 21st day of the menstrual cycle. These findings suggest that hormonal fluctuations during the menstrual cycle alter pelvic floor muscle activity.

Research paper thumbnail of M047 Pulsatility of Androgens in the Nonclassical Congenital Adrenal Hyperplasia (NC‐Cah)

International Journal of Gynecology & Obstetrics, 2012

Research paper thumbnail of Lifestyle interventions and quality of life for women with polycystic ovary syndrome

Medicine, 2019

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in wom... more Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. PCOS has a significant negative impact on the health-related quality of life (HRQoL) and psychological function of women, of which there are reports of high levels of depression in women with PCOS compared to those without PCOS. However, the evidence surrounding the effects of exercise and/or dietary intervention participation on the HRQoL of women with PCOS is limited. Therefore, our objective is to examine the effects of lifestyle interventions (definition include exercise-only, diet-only, exercise + diet and behavioral or combined) on health-related quality of life or general quality of life in women with PCOS. Methods: We will conduct an update of systematic review and we will follow the recommendations and guidelines of the Cochrane handbook for systematic reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P). We will search the studies in the following databases: MEDLINE. PubMed, PsychINFO, Embase, SportDiscus, Web of Science, Cochrane Database (via Cochrane library), Cochrane Controlled Register of Trials (CENTRAL), and Google Scholar (advance). Manual search of the reference list of identified works, without language and year restrictions. The process of study selection and data extraction will be performed independently by 2 reviewers, with a third reviewer being responsible for the final decision in case of disagreement between the first two. We will use Egger funnel chart to evaluate possible publication biases, in addition, when possible we will perform a subgroup/meta-regression analysis. The strength of the evidence will be assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).

Research paper thumbnail of Behavior of the uterine cervical length in normal pregnancies evaluated by transvaginal sonography

Journal of Perinatal Medicine, 2001

Research paper thumbnail of �ndices De Obesidade Central e Fatores De Risco Cardiovascular Na S�ndrome Dos Ov�rios Polic�sticos

Research paper thumbnail of Perfil da p�s-gradua��o em Ginecologia e Obstetr�cia no Brasil

Research paper thumbnail of Psychophysiological responses of women with polycystic ovary syndrome during sessions of high-intensity interval training

Human Movement, 2022

Purpose. The study described psychophysiological responses (perceived exertion, affective respons... more Purpose. The study described psychophysiological responses (perceived exertion, affective response) of women with polycystic ovary syndrome (PcOS) throughout 10 sessions of high-intensity interval training (HIIT). Methods. Overall, 12 physically inactive women with PcOS (age: 26.2 ± 4.1 years; body mass index: 28.5 ± 6.3 kg/m 2) performed 10 running HIIT sessions of 50 min [10 × 1-min intervals, 90% of maximal heat rate (HRmax); 3-min active recovery periods, 70% HRmax], including 5-min warm-up and cool-down, with 48-hour intervals. HRmax, rating of perceived exertion (RPE, Borg cR10 scale), and affective responses (Feeling Scale) were assessed in the last 10 s of each interval and recovery period. Each session responses were grouped into session parts (beginning, 1-3; middle, 4-7; end, 8-10) for intervals and recovery periods separately. The generalized estimating equation model served to compare %HRmax, RPE, and affective valence between session parts. Results. The intensities of intervals (p < 0.001) and recovery (p < 0.001) increased from session beginning to end, as did RPE of intervals (p < 0.001) and recovery (p < 0.001). Interval affective responses were lower at end compared with beginning (p < 0.040). HIIT intensity (%HRmax) presented a small coefficient of variation (cV, ca. 3%); RPE exhibited medium cV (ca. 20%) between 10 HIIT sessions. Conclusions. Psychophysiological responses of physically inactive PcOS women to running HIIT demonstrate positive affective valence at the beginning of HIIT sessions. As the session progresses, affective valence decreases to neutral and RPE increases.

Research paper thumbnail of Considerações sobre a gestação na vigência do uso de metformina, em portadoras da síndrome dos ovários policísticos; Considerations about pregnancy following …

Reprod. clim, 2003

Resumo: O uso da metformina, um agente hipoglicemiante oral que aumenta a sensibilidade à insulin... more Resumo: O uso da metformina, um agente hipoglicemiante oral que aumenta a sensibilidade à insulina, tem sido amplamente difundido entre os ginecologistas na abordagem da síndrome dos ovários policísticos (SOP). Enquanto muitos benefícios ...

Research paper thumbnail of Serum leptin levels in healthy postmenopausal women receiving raloxifene

Research paper thumbnail of Sí­ndrome dos ovários policí­sticos e sí­ndrome metabólica: uma associação significativa com implicações clí­nicas

1Aluno bolsista PPq/UFRN; 2Colaboradora, Maternidade Escola Januário Cicco; 3Colaboradora, Labora... more 1Aluno bolsista PPq/UFRN; 2Colaboradora, Maternidade Escola Januário Cicco; 3Colaboradora, Laboratório Integrado de Análises Clínicas da Faculdade de Farmácia; 4Professora Orientadora, Departamento de Tocoginecologia do Centro de Ciências da Saúde; ...

Research paper thumbnail of Resistência à insulina em mulheres com síndrome dos ovários policísticos: relação com as variáveis antropométricas e bioquímicas

Revista Brasileira de Ginecologia e Obstetrícia, Feb 1, 2012

OBJETIVO: Analisar a prevalência de resistência à insulina de acordo com diferentes medidas antro... more OBJETIVO: Analisar a prevalência de resistência à insulina de acordo com diferentes medidas antropométricas e bioquímicas em mulheres com síndrome dos ovários policísticos. MÉTODOS: Foram analisadas, retrospectivamente, 189 pacientes com síndrome dos ovários policísticos. O diagnóstico de resistência à insulina foi obtido utilizando-se insulinemia, HOMA-IR, QUICKI, índice de sensibilidade à insulina e relação glicemia/insulina. Foram utilizados o índice de massa corpórea e o lipid accumulation product. Para análise dos resultados, aplicou-se a estatística descritiva, a ANOVA, o pós-teste de Tukey e a correlação de Pearson. RESULTADOS: As pacientes apresentaram média de idade de 24,9±5,2 e de índice de massa corpórea de 31,8±7,6. O percentual de pacientes obesas foi de 57,14%. Dentre os métodos de investigação de resistência à insulina, o índice de sensibilidade à insulina foi a técnica que mais detectou (56,4%) a presença de resistência à insulina nas mulheres com síndrome dos ovários policísticos. Em 87% das pacientes obesas, detectou-se a resistência à insulina. A relação glicemia/insulinemia de jejum e o índice de sensibilidade à insulina apresentaram correlação forte com o lipid accumulation product. CONCLUSÃO: A prevalência de resistência à insulina variou de acordo com o método utilizado e foi maior quanto maior o índice de massa corpórea. O lipid accumulation product também está relacionado à resistência à insulina.

Research paper thumbnail of Irregularidade do ciclo menstrual no menacme como marcador para fatores de risco cardiovasculares na pós-menopausa

Arquivos Brasileiros De Endocrinologia E Metabologia, Oct 1, 2006

Menstrual Cycle Irregularity as a Marker of Cardiovascular Risk Factors at Postmenopausal Years. ... more Menstrual Cycle Irregularity as a Marker of Cardiovascular Risk Factors at Postmenopausal Years. To evaluate the association between cardiovascular risk factors (CVRF) during postmenopausal years and previous menstrual irregularity during reproductive years, we performed a case-control study in 414 postmenopausal women (mean age 60.4 ± 5.5 years; BMI 25.3 ± 4.7 kg/m 2). The variables assessed were: menstrual cycle characteristics at age 20-35y (independent) and records of arterial hypertension, dyslipidemia, diabetes mellitus, and coronary heart disease (dependent). Statistical analysis used the chi-square test and logistic regression, adjusting for potential confounders for cardiovascular risk, with significance set at 5%. Women reporting previous menstrual irregularity were associated with increased risk for some CVRF [adjusted odds ratio (OR) 2.14; CI-95%= 1.02-4.48], when compared with those reporting regular menstrual cycles. Stratified analysis demonstrated significant associations of previous menstrual irregularity with: arterial hypertension [OR= 2.74; CI-95%= 1.39-5.41), hypercholesterolemia (OR= 2.32; CI-95%= 1.17-4.59), hypertriglyceridemia (OR= 2.09; CI-95%=1.10-4.33), and coronary angioplasty artigo original

Research paper thumbnail of Terapia de reposição hormonal na pós-menopausa: efeitos sobre o sistema hemostático e risco de trombose

Femina, 2003

página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Sá, Marcos Felipe Silva de. ex... more página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Sá, Marcos Felipe Silva de. experimental, Documentos relacionados. Id: 357946. Autor: Azevedo, George Dantas de; Franco, Rendrik França; Maranhão, Técia Maria de Oliveira; Sá, Marcos Felipe Silva de. ...

Research paper thumbnail of Macroprolactinemia: as vantagens do rastreamento na prática clínica

Revista Brasileira de Ginecologia e Obstetrícia, Jul 1, 2010

Fernanda vieira rodovalho-callegari 2 Maristela carbol patta 3 patrícia Margareth lizarelli 4 car... more Fernanda vieira rodovalho-callegari 2 Maristela carbol patta 3 patrícia Margareth lizarelli 4 carolina sales vieira 5 técia Maria oliveira Maranhão 6 Editorial A prolactina (PRL) é um hormônio hipofisário que circula em diferentes formas moleculares: "little" ou "small", monomérica, que é biologicamente ativa (Peso Molecular 23 kDa); "big" (PM 50-60 kDa); "big-big" (PM 150-170 kDa), também conhecida como macroprolactina, que é constituída pela molécula da PRL ligada a um complexo de IgG 1,2. No soro de indivíduos normais, a forma monomérica é a predominante (85-95%), enquanto a "big-big" PRL constitui a forma menos frequente (<1%) 3. A hiperprolactinemia é uma das alterações endócrinas mais comuns do eixo hipotálamohipofisário, acometendo 0,4% da população adulta e 9-17% das mulheres com distúrbios reprodutivos. Sua etiologia é variada e, excluindo-se as causas fisiológicas, o uso de algumas medicações e o hipotireoidismo, os tumores hipofisários secretores ou não de PRL representam a principal causa de hiperprolactinemia. As manifestações clínicas da hiperprolactinemia compreendem uma série de sintomas como os distúrbios menstruais, galactorreia, infertilidade, hirsutismo e alterações neurooftalmológicas, estas últimas quando a causa é um tumor de maiores proporções. A longo prazo, a hiperprolactinemia pode levar à osteoporose como consequência do hipoestrogenismo que se estabelece nessas pacientes. A associação desses sintomas e sinais com elevação dos níveis de PRL plasmática torna obrigatória, portanto, a investigação da etiologia com foco especial na detecção de um tumor hipofisário, principalmente os secretores de PRL, chamados prolactinomas, o que é feito sistematicamente através de exames de imagem como a Tomografia Computadorizada (TC) e a Ressonância Nuclear Magnética (RNM) 4 .

Research paper thumbnail of Pelvic floor muscle thickness in women with polycystic ovary syndrome

Clinical and Experimental Obstetrics & Gynecology, Dec 10, 2018

Objective: To evaluate pelvic floor muscle (PFM) thickness in women with polycystic ovary syndrom... more Objective: To evaluate pelvic floor muscle (PFM) thickness in women with polycystic ovary syndrome (PCOS) group and compare it to those with normal menstrual cycle (control group). Materials and Methods: Transperineal ultrasound examination was used to evaluate the thickness of the bilateral pelvic floor muscles Results: The mean age was 25.1 ± 2.1 and 24.2 ± 1.9 years in PCOS and control groups, respectively (p > 0.05). Body mass index averaged 22.5 ± 0.9 in the control group and 27.8 ± 2.6 in the PCOS group (p = 0.03). There was no difference between the thickness of the pelvic floor muscles (PCOS group: right 1.12 ± 0.5, left 1.0 ± 0.6 and control group: right 0.89 ± 0.6 and left 0.94 ± 0.4. Conclusions: There was no differences in pelvic floor muscle thickness identified by ultrasound. However, the PCOS group exhibited a tendency to greater thickness. This may be due to the state of hyperandrogenism or abdominal overload.

Research paper thumbnail of Breast changes in pregnancy and lactation observed by ultrasonography

Clinical and Experimental Obstetrics & Gynecology, 2019

Purpose of Investigation: To assess the ultrasound aspects of breasts and laser Doppler flow meas... more Purpose of Investigation: To assess the ultrasound aspects of breasts and laser Doppler flow measurements of the internal mammary arteries (IMA) in pregnant, lactating, and non-pregnant (control) women. Materials and Methods: A cross-sectional observation study of 102 women, divided into three groups: control (CG), third trimester (G3), and lactation group (LG). The study variables were skin, subcutaneous adipose tissue, fibroglandular tissue, retromammary adipose tissue thickness, duct diameter, and pulsatility (PI) and resistance indices (RI) of the internal mammary arteries. Statistical analysis calculated the means and standard deviations, using two models Multivariate Analysis of Variance (MANOVA) models to assess the effect of groups on the mean values found and adjusted ANOVA models for individual means. The Tukey-Kramer multiple comparisons test was used to analyze intergroup. Results: There was no intergroup age difference (mean = 27 ± 4.76 years). A significant difference was observed between the G3/LG and the CG in terms of skin (p = 0.001), fibroglandular tissue thickness, duct diameter, and laser Doppler flow measurements of the IMA (all three with p < 0.001) and subcutaneous adipose tissue (p = 0.045). Conclusion: This study showed alterations in skin, subcutaneous adipose tissue, fibroglandular tissue, and duct diameter measurements, with a difference between pregnant/lactating women and the non-pregnant controls.

Research paper thumbnail of Use of androgens at different stages of life: climacterium

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2022

• Female sexual dysfunction (FSD) includes hypoactive sexual desire disorders (HSDD) and sexual a... more • Female sexual dysfunction (FSD) includes hypoactive sexual desire disorders (HSDD) and sexual arousal, orgasm disorders and genito pelvic pain disorder, and vaginal penetration disorders. • Female sexual dysfunction affects around 45% of women, most of them postmenopausal. • The genitourinary menopause syndrome (GMS) includes signs and symptoms related to atrophy of the genital tract and predisposes to vaginal and/or urinary infections, in addition to interfering with the woman's sexual performance. • There is a decline in cognitive function in postmenopausal women, and estrogens and androgens appear to independently influence cognitive activity. • The characterization of postmenopausal androgen deficiency and the prescription of androgen therapy is still a controversial topic.

Research paper thumbnail of Use of androgens at different stages of life: reproductive period

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2021

Research paper thumbnail of The effect of exercise as an intervention for women with polycystic ovary syndrome

Medicine, 2020

Background: Polycystic ovary syndrome (PCOS) affects reproductive-aged women and is associated wi... more Background: Polycystic ovary syndrome (PCOS) affects reproductive-aged women and is associated with increased prevalence of serious clinical problems including: reproductive implications, metabolic dysfunction, and cardiovascular risk. Physical activity offers several health benefits for women with PCOS. The aim of this systematic review was to synthesize evidence on the effect of different types of exercise on reproductive function and body composition for women with PCOS. Methods: This was a systematic review and meta-analysis of randomized controlled trials (RCTs) following recommended review methods. We searched 6 databases: Cumulative Index of Nursing and Allied Health Literature; Embase; MEDLINE (via Ovid); PubMed; Sport Discus; and Web of Science; and we developed search strategies using a combination of Medical Subject Headings terms and text words related to exercise interventions for women with PCOS. There was no restriction on language or publication year. The search was ...

Research paper thumbnail of Clustering of risk factors for cardiometabolic diseases in low-income, female adolescents

Archives of endocrinology and metabolism, Jan 16, 2016

Objective To assess the prevalence and clustering patterns of cardiometabolic risk factors among ... more Objective To assess the prevalence and clustering patterns of cardiometabolic risk factors among low-income, female adolescents. Materials and methods Cross-sectional study involving 196 students of public schools (11-19 years old). The following risk factors were considered in the analysis: excess weight, central obesity, dyslipidemia, high blood pressure, and high fasting glucose. The ratio between observed and expected prevalence and its confidence interval were used to identify clustering of risk factors that exceeded expected prevalence in the population. Results The most prevalent risk factors were dyslipidemia (70.9%), and central obesity (39.8%), followed by excess weight (29.6%), and high blood pressure (12.8%). A total of 42.9% of adolescents had two or more risk factors, and 24% had three or more. Excess weight, central obesity, and dyslipidemia were common risk factors in the clustering patterns that showed higher-than-expected prevalence. Conclusions Clustering of risk ...

Research paper thumbnail of Is there a difference in the electromyographic activity of the pelvic floor muscles across the phases of the menstrual cycle?

Journal of Physical Therapy Science, 2015

To evaluate the electrical activity of the pelvic floor muscle in women during the follicular, ov... more To evaluate the electrical activity of the pelvic floor muscle in women during the follicular, ovulatory, and luteal phases of the menstrual cycle and its correlation with estradiol and total testosterone levels. [Subjects and Methods] This cross-sectional study involved 30 women with ovulatory menstrual cycles. Total testosterone and estradiol levels were measured and the muscle tone and maximum voluntary contraction of the pelvic floor muscles were evaluated using surface electromyography. [Results] Muscle tone was significantly lower during the follicular (21.1±3.3 μV) and ovulatory (27.1±5.9 μV) phases than the luteal phase (30.4±4.1 μV). The maximum voluntary contraction was not different across phases. The estradiol level on the 7th day of the menstrual cycle showed a strong positive correlation with muscle tone and maximum voluntary contraction, and the testosterone level was positively correlated with muscle tone on the 21st day. [Conclusion] Women have better muscle tone during the luteal phase. The muscle tone and maximum voluntary contraction were strongly correlated with the estradiol level on the 7th day, and the muscle tone was correlated with the testosterone level on the 21st day of the menstrual cycle. These findings suggest that hormonal fluctuations during the menstrual cycle alter pelvic floor muscle activity.

Research paper thumbnail of M047 Pulsatility of Androgens in the Nonclassical Congenital Adrenal Hyperplasia (NC‐Cah)

International Journal of Gynecology & Obstetrics, 2012

Research paper thumbnail of Lifestyle interventions and quality of life for women with polycystic ovary syndrome

Medicine, 2019

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in wom... more Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. PCOS has a significant negative impact on the health-related quality of life (HRQoL) and psychological function of women, of which there are reports of high levels of depression in women with PCOS compared to those without PCOS. However, the evidence surrounding the effects of exercise and/or dietary intervention participation on the HRQoL of women with PCOS is limited. Therefore, our objective is to examine the effects of lifestyle interventions (definition include exercise-only, diet-only, exercise + diet and behavioral or combined) on health-related quality of life or general quality of life in women with PCOS. Methods: We will conduct an update of systematic review and we will follow the recommendations and guidelines of the Cochrane handbook for systematic reviews and Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P). We will search the studies in the following databases: MEDLINE. PubMed, PsychINFO, Embase, SportDiscus, Web of Science, Cochrane Database (via Cochrane library), Cochrane Controlled Register of Trials (CENTRAL), and Google Scholar (advance). Manual search of the reference list of identified works, without language and year restrictions. The process of study selection and data extraction will be performed independently by 2 reviewers, with a third reviewer being responsible for the final decision in case of disagreement between the first two. We will use Egger funnel chart to evaluate possible publication biases, in addition, when possible we will perform a subgroup/meta-regression analysis. The strength of the evidence will be assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).

Research paper thumbnail of Behavior of the uterine cervical length in normal pregnancies evaluated by transvaginal sonography

Journal of Perinatal Medicine, 2001

Research paper thumbnail of �ndices De Obesidade Central e Fatores De Risco Cardiovascular Na S�ndrome Dos Ov�rios Polic�sticos

Research paper thumbnail of Perfil da p�s-gradua��o em Ginecologia e Obstetr�cia no Brasil