THULIR SIDDHA - Academia.edu (original) (raw)
Papers by THULIR SIDDHA
Journal Pharmacognosy and Phytochemistry, 2018
Background: Medicinal plants are playing very active role in traditional medicines for the treatm... more Background: Medicinal plants are playing very active role in traditional medicines for the treatment of various ailments. Thiripala chooranam tablet, a polyherbal Siddha formulation is used for treating gastric ulcer, skin disease, constipation, piles, wounds, gum bleeding, liver diseases etc. Therapeutic efficacy of many Siddha formulations depends upon the standardization and authentication of medicinal plants used and hence ensures reproducible quality of herbal products which will lead to safety, quality and efficacy of end products. The drug is being used as a prophylactic and as treatment option in diabetes. However, its effect on prediabetes has not been carried out. The aim of the doctoral study is to evaluate the efficacy of Thiripala Chooranam tablet in Munnerizhivu (Impaired Glucose Tolerance-IGT). Objective: To interpret the characteristic parameters of Thiripala chooranam tablet to conform its identity, quality and purity. Methods: Thiripala chooranam tablet was evaluat...
Atharva Scientific Publication, 2019
A chronic ulcer is that, which does not heal within three months. Diabetic, arterial and venous u... more A chronic ulcer is that, which does not heal within three months. Diabetic, arterial and venous ulcers are the common cause for non-healing lower extremity ulcers. The prevalence of chronic leg ulcers is 0.6-3% in people over 60 years and 5% in those over 80 years. Here, we report a case series of 6 patients with chronic non-healing ulcers. All the 6 patients received topical application of Siddha medicine. 'Leg Ulcer Measurement Tool (LUMT)' scoring system was used to assess the severity, prognosis and for follow-up treatment. After the 6 weeks of treatment, 33% (n=2) have ulcer size more than 5cm, 16% (n=1) have exudate in their ulcers, none of them have necrotic tissues, leg edema and peri-ulcer affected skin in their ulcers. It was found that the patients treated with Siddha medicine have satisfactory improvement in the non-healing lower extremity ulcers.
The use of Salamisri (Orchis mascula) has a very long history dating back to centuries mainly as ... more The use of Salamisri (Orchis mascula) has a very long history dating back to centuries mainly as an alternate to Arrowroot and Coffee. It has also rich Medicinal properties as potent Aphrodisiac and Tonic. Review of Siddha literature reveals Salamisri to be a promising food supplement / medicine especially to the Old age related problems.
In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs) far exce... more In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs) far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally .10:1 whereas on a primitive human diet it was closer to 1:1. Diets fed to intensively farmed livestock have followed a similar trend. Both n-6 and n-3 PUFAs can influence reproductive processes through a variety of mechanisms. They provide the precursors for prostaglandin synthesis and can modulate the expression patterns of many key enzymes involved in both prostaglandin and steroid metabolism. They are essential components of all cell membranes. The proportions of different PUFAs in tissues of the reproductive tract reflect dietary consumption. PUFA supplements (particularly n-3 PUFAs in fish oil) are promoted for general health reasons. Fish oils may also benefit fertility in cattle and reduce the risk of preterm labor in women, but in both cases current evidence to support this is inconclusive. Gammalinolenic acid containing oils can alter the types of prostaglandins produced by cells in vitro, but published data to support claims relating to effects on reproductive health are lacking. Spermatozoa require a high PUFA content to provide the plasma membrane with the fluidity essential at fertilization. However, this makes spermatozoa particularly vulnerable to attack by reactive oxygen species, and lifestyle factors promoting oxidative stress have clear associations with reduced fertility. Adequately powered trials that control for the ratios of different PUFAs consumed are required to determine the extent to which this aspect of our diets does influence our fertility.
The Indian subcontinent is enriched by a variety of flora -both medicinal and aromatic plants. Th... more The Indian subcontinent is enriched by a variety of flora -both medicinal and aromatic plants. This extensive flora has been greatly utilized as a source of many drugs in the Indian traditional systems of medicine. This study aims at exploring the pharmacognosy, phytochemistry, physicochemical and TLC analysis of a Siddha polyherbal formulation Nilapanai chooranam. The raw materials were authenticated by a pharmacognosist. The macroscopic characters and the powder microscopy of the chooranam revealed the presence of all those ingredients in the final product. The preliminary phytochemical analysis of Nilapanai choornam revealed the presence of Glycoside, Tannins, alkaloids, Triterpenes, Flavonoids. In Thin layer chromatographic analysis the solvent front was standardized as Petroleum ether: Chloroform: Methanol 1:0:5:0.1. The methanol, chloroform and ether extracts were fractionized.
The aim of the study is to evaluate the effect of the aqueous extract of Moringa oleifera on repr... more The aim of the study is to evaluate the effect of the aqueous extract of Moringa oleifera on reproductive abilities of male albino rats. The aqueous extract of M. oleifera seed at doses of 100, 200 and 500 mg/kg were administrated for 21 days. The general mating behaviour and libido activity was studied. The effect of the extract on body weight, reproductive and vital organ weight were determined. The most effective aqueous extract dose was further studied for its effect on sperm count and histoarchitecture of testes of experimental animal. Similarly adverse effects and acute toxicity of the extract were evaluated. Oral administration of aqueous extract at doses of 100, 200 and 500 mg/kg significantly increased the Mounting Frequency, Intromission Frequency and Ejaculation latency with reduction in Mounting Latency, Intromission Latency and Post Ejaculatory Interval. It also significantly increased the libido and sperm count in experimental animal. The extract was also observed to be devoid of any adverse effects and acute toxicity. The results of the present study demonstrate that aqueous extract of M. oleifera seed enhance sexual behaviour in male rats. It also thus provides a rationale for the traditional use of M. oleifera as acclaimed aphrodisiac and for the management of male sexual disorders.
Background: The Ayurvedic medicinal system claims Mucuna pruriens (MP) to possess pro-male fertil... more Background: The Ayurvedic medicinal system claims Mucuna pruriens (MP) to possess pro-male fertility, aphrodisiac and adaptogenic properties. Some scientific evidence also supports its pro-male fertility properties; however, the mechanism of its action is not yet clear. The present study aimed at demonstrating spermatogenic restorative efficacy of MP and its major constituent L-DOPA (LD), and finding the possible mechanism of action thereof in a rat model. Methodology/Findings: Ethinyl estradiol (EE) was administered at a rate of 3 mg/kg body weight (BW)/day for a period of 14 days to generate a rat model with compromised spermatogenesis. MP and LD were administered in two separate groups of these animals starting 15 th day for a period of 56 days, and the results were compared with an auto-recovery (AR) group. Sperm count and motility, testis histo-architecture, level of reactive oxygen species (ROS), mitochondrial membrane potential (MMP), apoptosis, peripheral hormone levels and testicular germ cell populations were analysed, in all experimental groups. We observed efficient and quick recovery of spermatogenesis in MP and LD groups in comparison to the auto-recovery group. The treatment regulated ROS level, apoptosis, and mitochondrial membrane potential (MMP), recovered the hypothalamic-pituitary-gonadal axis and the number of testicular germ cells, ultimately leading to increased sperm count and motility.
In the last decades Moringa oleifera Lam. and Pseuderanthemum palatiferum (Nees) Radlk., the medi... more In the last decades Moringa oleifera Lam. and Pseuderanthemum palatiferum (Nees) Radlk., the medicinal plants with broad spectrum properties, have been highly popular. These 2 plant species are believed to be able to cure many diseases and promote health status via immunity boosting. In addition, they have been reported to contain several antioxidants that help to promote functions of body systems. Nevertheless, no scientific research has been reported yet on their antioxidant capacity in reproductive system. This research was, thus, aimed at evaluating the anti-peroxidative activity of these 2 plant species by determining their capacity to reduce malondialdehyde (MDA) level in reproductive organs and accessory glands of treated rats. Adult male rats were administered orally with the leaf extracts from M. oleifera at 60, 120, 180 and 240 mg/kg body weight and from P. palatiferum at 5, 10, 15, 20 mg/kg body weight for 60 consecutive days. It was found that testicular MDA level was not significantly different from those of controls (P>0.05) although a tentatively decreased MDA level was observed. However, MDA levels in the investigated reproductive accessory glands, seminal vesicle and prostate gland, were significantly (P<0.05) lower than those of controls. It was also found that the extract from M. oleifera had higher capacity to reduce lipidperoxidation than that from P. palatiferum.
Exposure to heavy metals has been known for its adverse effects on many body organs and Systems a... more Exposure to heavy metals has been known for its adverse effects on many body organs and Systems and thus their functions. Hence, this study was aimed to determine the ability of polyphenolic-rich Moringa oleifera Leaf Extract (MoE) in protecting rat testis against chromium-induced impairments based on some histopathological and biochemical clarification. Forty male Wistar rats were divided into four groups of ten animals each. The animals were administered either 150pp mg/kg potassium dichromate or 60 mg/kg body/weight of Moringa Oleifera extract (MoE) or the combination, for 100 days. The animals were sacrificed and testicular weight and volume and sperm parameters were determined. Chromium treated groups exhibited a significantly decrease in testis weight/volume, testis weight/body weight ratio, sperm parameters compared to the control and Moringa oleifera treated groups. Concurrent exposure to chromium and Moringa Oleifera extract significantly enhanced the sperm parameters compared to rats exposed to chromium alone. This showed that changes brought about by chromium toxicity were mildly averted by simultaneous treatment of Moringa oleifera leaf extract. This study concludes that chronic exposure to chromium produces marked testicular toxicity which can be prevented by concomitant administration of Moringa oleifera leaf extract.
Fertility control is an issue of global and national public health concern. Many studies have bee... more Fertility control is an issue of global and national public health concern. Many studies have been done on the male contraception. The traditional use of medicinal plants to treat different sorts of diseases, including fertility related problems is widespread throughout the world as many plant substances are known for their interferences with the male reproductive system. The present review is an attempt to summarize the fertility regulatory plants with part used, type of extract/isolated compounds (active principles) along with animal model used. The literature covered is of 25 years i.e. from 1980 to 2005 for 105 plants showing antifertility activity in males.
Medicinal plants, is a common word which can utter in every one's mouth that are helpful in treat... more Medicinal plants, is a common word which can utter in every one's mouth that are helpful in treating many diseases which can't be done by even allopathic medicine. Among those the birth control and at the same time increasing the fertility in human beings are both become major problems now a days. This review article which is having 63 plants and 122 references with antifertility activity and profertility activity including some other pharmacological activities. This review article views that not to avoid the plants having a small percentage of antifertility activity but also consider their pharmacological activities as they are much more helpful in treating different types of diseases and this may be helpful to researchers those who are in the field of pharmacological activities of medicinal plants.
There are several medicinal plants which are having several pharmacological activities. These med... more There are several medicinal plants which are having several pharmacological activities. These medicinal plants are being used to treat several diseases. The present study deals that a plant which shows fertility activity and also additional pharmacological activities. With the help of available literature, we have analyzed that which type of pharmacological activity is more among selected medicinal plants. Antioxidant activity is high and antinociceptive activity is less among 63 medicinal plants. Anthelmintic, anti hyposensitive, aphrodiasic etc are screened in these medicinal plants and reported that the activities are very least. This type of collection may helpful to the pharmacists to concentrate the study on less expressed pharmacological activities.
Dill is herbaceous and aromatic herb used in order to convenient and shorter labor in Iran. The o... more Dill is herbaceous and aromatic herb used in order to convenient and shorter labor in Iran. The objective of this study was to evaluate the effect of Dill seed on uterus contractions in active phase of labor. In this historical cohort study, 40 women used Dill seed infusion in the case group and 60 women used nothing in the control group. Interpretable electronic fetal monitoring was obtained for half an hour at the beginning of the active phase. The Fall: Rise ratio was calculated by measuring the duration of time for a contraction to return to its baseline from its peak (fall) divided to the duration of its rise time to its peak (rise).The number of contractions in the case group was significantly more than the control group. The ratio of contraction's fall time to its rise time in the case group was shorter than the control group. The study showed that Dill seed shortens duration of the first stage of labor. Since there is not enough information about correct amount and time for consuming this herb, more complete studies are needed.
Sex has always been a taboo subject in Asian society. However, over the past few years, awareness... more Sex has always been a taboo subject in Asian society. However, over the past few years, awareness in the field of men's sexual health has improved, and interest in sexual health research has recently increased. The epidemiology and prevalence of erectile dysfunction, hypogonadism and premature ejaculation in Asia are similar in the West. However, several issues are specific to Asian males, including culture and beliefs, awareness, compliance and the availability of traditional/complementary medicine. In Asia, sexual medicine is still in its infancy, and a concerted effort from the government, relevant societies, physicians and the media is required to propel sexual medicine to the forefront of health care.
Here we investigated the effects of Tribulus terrestris L. on sperm morphology and acrosome react... more Here we investigated the effects of Tribulus terrestris L. on sperm morphology and acrosome reaction in subjects with oligoasthenoteratozoospermia. A double-blind placebo-controlled trial was performed with 30 primary and secondary infertile men. Half received oral Tribulus (Libilov, 500mg dose) three times per day for 60 days, and the rest were given sugar pills. The ejaculate volume, sperm concentration, morphology, acrosome reactions, and other parameters were evaluated before and after treatment.
Journal Pharmacognosy and Phytochemistry, 2018
Background: Medicinal plants are playing very active role in traditional medicines for the treatm... more Background: Medicinal plants are playing very active role in traditional medicines for the treatment of various ailments. Thiripala chooranam tablet, a polyherbal Siddha formulation is used for treating gastric ulcer, skin disease, constipation, piles, wounds, gum bleeding, liver diseases etc. Therapeutic efficacy of many Siddha formulations depends upon the standardization and authentication of medicinal plants used and hence ensures reproducible quality of herbal products which will lead to safety, quality and efficacy of end products. The drug is being used as a prophylactic and as treatment option in diabetes. However, its effect on prediabetes has not been carried out. The aim of the doctoral study is to evaluate the efficacy of Thiripala Chooranam tablet in Munnerizhivu (Impaired Glucose Tolerance-IGT). Objective: To interpret the characteristic parameters of Thiripala chooranam tablet to conform its identity, quality and purity. Methods: Thiripala chooranam tablet was evaluat...
Atharva Scientific Publication, 2019
A chronic ulcer is that, which does not heal within three months. Diabetic, arterial and venous u... more A chronic ulcer is that, which does not heal within three months. Diabetic, arterial and venous ulcers are the common cause for non-healing lower extremity ulcers. The prevalence of chronic leg ulcers is 0.6-3% in people over 60 years and 5% in those over 80 years. Here, we report a case series of 6 patients with chronic non-healing ulcers. All the 6 patients received topical application of Siddha medicine. 'Leg Ulcer Measurement Tool (LUMT)' scoring system was used to assess the severity, prognosis and for follow-up treatment. After the 6 weeks of treatment, 33% (n=2) have ulcer size more than 5cm, 16% (n=1) have exudate in their ulcers, none of them have necrotic tissues, leg edema and peri-ulcer affected skin in their ulcers. It was found that the patients treated with Siddha medicine have satisfactory improvement in the non-healing lower extremity ulcers.
The use of Salamisri (Orchis mascula) has a very long history dating back to centuries mainly as ... more The use of Salamisri (Orchis mascula) has a very long history dating back to centuries mainly as an alternate to Arrowroot and Coffee. It has also rich Medicinal properties as potent Aphrodisiac and Tonic. Review of Siddha literature reveals Salamisri to be a promising food supplement / medicine especially to the Old age related problems.
In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs) far exce... more In Westernized societies, average consumption of n-6 polyunsaturated fatty acids (PUFAs) far exceeds nutritional requirements. The ratio of n-6 to n-3 PUFAs is generally .10:1 whereas on a primitive human diet it was closer to 1:1. Diets fed to intensively farmed livestock have followed a similar trend. Both n-6 and n-3 PUFAs can influence reproductive processes through a variety of mechanisms. They provide the precursors for prostaglandin synthesis and can modulate the expression patterns of many key enzymes involved in both prostaglandin and steroid metabolism. They are essential components of all cell membranes. The proportions of different PUFAs in tissues of the reproductive tract reflect dietary consumption. PUFA supplements (particularly n-3 PUFAs in fish oil) are promoted for general health reasons. Fish oils may also benefit fertility in cattle and reduce the risk of preterm labor in women, but in both cases current evidence to support this is inconclusive. Gammalinolenic acid containing oils can alter the types of prostaglandins produced by cells in vitro, but published data to support claims relating to effects on reproductive health are lacking. Spermatozoa require a high PUFA content to provide the plasma membrane with the fluidity essential at fertilization. However, this makes spermatozoa particularly vulnerable to attack by reactive oxygen species, and lifestyle factors promoting oxidative stress have clear associations with reduced fertility. Adequately powered trials that control for the ratios of different PUFAs consumed are required to determine the extent to which this aspect of our diets does influence our fertility.
The Indian subcontinent is enriched by a variety of flora -both medicinal and aromatic plants. Th... more The Indian subcontinent is enriched by a variety of flora -both medicinal and aromatic plants. This extensive flora has been greatly utilized as a source of many drugs in the Indian traditional systems of medicine. This study aims at exploring the pharmacognosy, phytochemistry, physicochemical and TLC analysis of a Siddha polyherbal formulation Nilapanai chooranam. The raw materials were authenticated by a pharmacognosist. The macroscopic characters and the powder microscopy of the chooranam revealed the presence of all those ingredients in the final product. The preliminary phytochemical analysis of Nilapanai choornam revealed the presence of Glycoside, Tannins, alkaloids, Triterpenes, Flavonoids. In Thin layer chromatographic analysis the solvent front was standardized as Petroleum ether: Chloroform: Methanol 1:0:5:0.1. The methanol, chloroform and ether extracts were fractionized.
The aim of the study is to evaluate the effect of the aqueous extract of Moringa oleifera on repr... more The aim of the study is to evaluate the effect of the aqueous extract of Moringa oleifera on reproductive abilities of male albino rats. The aqueous extract of M. oleifera seed at doses of 100, 200 and 500 mg/kg were administrated for 21 days. The general mating behaviour and libido activity was studied. The effect of the extract on body weight, reproductive and vital organ weight were determined. The most effective aqueous extract dose was further studied for its effect on sperm count and histoarchitecture of testes of experimental animal. Similarly adverse effects and acute toxicity of the extract were evaluated. Oral administration of aqueous extract at doses of 100, 200 and 500 mg/kg significantly increased the Mounting Frequency, Intromission Frequency and Ejaculation latency with reduction in Mounting Latency, Intromission Latency and Post Ejaculatory Interval. It also significantly increased the libido and sperm count in experimental animal. The extract was also observed to be devoid of any adverse effects and acute toxicity. The results of the present study demonstrate that aqueous extract of M. oleifera seed enhance sexual behaviour in male rats. It also thus provides a rationale for the traditional use of M. oleifera as acclaimed aphrodisiac and for the management of male sexual disorders.
Background: The Ayurvedic medicinal system claims Mucuna pruriens (MP) to possess pro-male fertil... more Background: The Ayurvedic medicinal system claims Mucuna pruriens (MP) to possess pro-male fertility, aphrodisiac and adaptogenic properties. Some scientific evidence also supports its pro-male fertility properties; however, the mechanism of its action is not yet clear. The present study aimed at demonstrating spermatogenic restorative efficacy of MP and its major constituent L-DOPA (LD), and finding the possible mechanism of action thereof in a rat model. Methodology/Findings: Ethinyl estradiol (EE) was administered at a rate of 3 mg/kg body weight (BW)/day for a period of 14 days to generate a rat model with compromised spermatogenesis. MP and LD were administered in two separate groups of these animals starting 15 th day for a period of 56 days, and the results were compared with an auto-recovery (AR) group. Sperm count and motility, testis histo-architecture, level of reactive oxygen species (ROS), mitochondrial membrane potential (MMP), apoptosis, peripheral hormone levels and testicular germ cell populations were analysed, in all experimental groups. We observed efficient and quick recovery of spermatogenesis in MP and LD groups in comparison to the auto-recovery group. The treatment regulated ROS level, apoptosis, and mitochondrial membrane potential (MMP), recovered the hypothalamic-pituitary-gonadal axis and the number of testicular germ cells, ultimately leading to increased sperm count and motility.
In the last decades Moringa oleifera Lam. and Pseuderanthemum palatiferum (Nees) Radlk., the medi... more In the last decades Moringa oleifera Lam. and Pseuderanthemum palatiferum (Nees) Radlk., the medicinal plants with broad spectrum properties, have been highly popular. These 2 plant species are believed to be able to cure many diseases and promote health status via immunity boosting. In addition, they have been reported to contain several antioxidants that help to promote functions of body systems. Nevertheless, no scientific research has been reported yet on their antioxidant capacity in reproductive system. This research was, thus, aimed at evaluating the anti-peroxidative activity of these 2 plant species by determining their capacity to reduce malondialdehyde (MDA) level in reproductive organs and accessory glands of treated rats. Adult male rats were administered orally with the leaf extracts from M. oleifera at 60, 120, 180 and 240 mg/kg body weight and from P. palatiferum at 5, 10, 15, 20 mg/kg body weight for 60 consecutive days. It was found that testicular MDA level was not significantly different from those of controls (P>0.05) although a tentatively decreased MDA level was observed. However, MDA levels in the investigated reproductive accessory glands, seminal vesicle and prostate gland, were significantly (P<0.05) lower than those of controls. It was also found that the extract from M. oleifera had higher capacity to reduce lipidperoxidation than that from P. palatiferum.
Exposure to heavy metals has been known for its adverse effects on many body organs and Systems a... more Exposure to heavy metals has been known for its adverse effects on many body organs and Systems and thus their functions. Hence, this study was aimed to determine the ability of polyphenolic-rich Moringa oleifera Leaf Extract (MoE) in protecting rat testis against chromium-induced impairments based on some histopathological and biochemical clarification. Forty male Wistar rats were divided into four groups of ten animals each. The animals were administered either 150pp mg/kg potassium dichromate or 60 mg/kg body/weight of Moringa Oleifera extract (MoE) or the combination, for 100 days. The animals were sacrificed and testicular weight and volume and sperm parameters were determined. Chromium treated groups exhibited a significantly decrease in testis weight/volume, testis weight/body weight ratio, sperm parameters compared to the control and Moringa oleifera treated groups. Concurrent exposure to chromium and Moringa Oleifera extract significantly enhanced the sperm parameters compared to rats exposed to chromium alone. This showed that changes brought about by chromium toxicity were mildly averted by simultaneous treatment of Moringa oleifera leaf extract. This study concludes that chronic exposure to chromium produces marked testicular toxicity which can be prevented by concomitant administration of Moringa oleifera leaf extract.
Fertility control is an issue of global and national public health concern. Many studies have bee... more Fertility control is an issue of global and national public health concern. Many studies have been done on the male contraception. The traditional use of medicinal plants to treat different sorts of diseases, including fertility related problems is widespread throughout the world as many plant substances are known for their interferences with the male reproductive system. The present review is an attempt to summarize the fertility regulatory plants with part used, type of extract/isolated compounds (active principles) along with animal model used. The literature covered is of 25 years i.e. from 1980 to 2005 for 105 plants showing antifertility activity in males.
Medicinal plants, is a common word which can utter in every one's mouth that are helpful in treat... more Medicinal plants, is a common word which can utter in every one's mouth that are helpful in treating many diseases which can't be done by even allopathic medicine. Among those the birth control and at the same time increasing the fertility in human beings are both become major problems now a days. This review article which is having 63 plants and 122 references with antifertility activity and profertility activity including some other pharmacological activities. This review article views that not to avoid the plants having a small percentage of antifertility activity but also consider their pharmacological activities as they are much more helpful in treating different types of diseases and this may be helpful to researchers those who are in the field of pharmacological activities of medicinal plants.
There are several medicinal plants which are having several pharmacological activities. These med... more There are several medicinal plants which are having several pharmacological activities. These medicinal plants are being used to treat several diseases. The present study deals that a plant which shows fertility activity and also additional pharmacological activities. With the help of available literature, we have analyzed that which type of pharmacological activity is more among selected medicinal plants. Antioxidant activity is high and antinociceptive activity is less among 63 medicinal plants. Anthelmintic, anti hyposensitive, aphrodiasic etc are screened in these medicinal plants and reported that the activities are very least. This type of collection may helpful to the pharmacists to concentrate the study on less expressed pharmacological activities.
Dill is herbaceous and aromatic herb used in order to convenient and shorter labor in Iran. The o... more Dill is herbaceous and aromatic herb used in order to convenient and shorter labor in Iran. The objective of this study was to evaluate the effect of Dill seed on uterus contractions in active phase of labor. In this historical cohort study, 40 women used Dill seed infusion in the case group and 60 women used nothing in the control group. Interpretable electronic fetal monitoring was obtained for half an hour at the beginning of the active phase. The Fall: Rise ratio was calculated by measuring the duration of time for a contraction to return to its baseline from its peak (fall) divided to the duration of its rise time to its peak (rise).The number of contractions in the case group was significantly more than the control group. The ratio of contraction's fall time to its rise time in the case group was shorter than the control group. The study showed that Dill seed shortens duration of the first stage of labor. Since there is not enough information about correct amount and time for consuming this herb, more complete studies are needed.
Sex has always been a taboo subject in Asian society. However, over the past few years, awareness... more Sex has always been a taboo subject in Asian society. However, over the past few years, awareness in the field of men's sexual health has improved, and interest in sexual health research has recently increased. The epidemiology and prevalence of erectile dysfunction, hypogonadism and premature ejaculation in Asia are similar in the West. However, several issues are specific to Asian males, including culture and beliefs, awareness, compliance and the availability of traditional/complementary medicine. In Asia, sexual medicine is still in its infancy, and a concerted effort from the government, relevant societies, physicians and the media is required to propel sexual medicine to the forefront of health care.
Here we investigated the effects of Tribulus terrestris L. on sperm morphology and acrosome react... more Here we investigated the effects of Tribulus terrestris L. on sperm morphology and acrosome reaction in subjects with oligoasthenoteratozoospermia. A double-blind placebo-controlled trial was performed with 30 primary and secondary infertile men. Half received oral Tribulus (Libilov, 500mg dose) three times per day for 60 days, and the rest were given sugar pills. The ejaculate volume, sperm concentration, morphology, acrosome reactions, and other parameters were evaluated before and after treatment.