Tahmidul Islam - Academia.edu (original) (raw)

Papers by Tahmidul Islam

Research paper thumbnail of Classification of EEG-Based Auditory Evoked Potentials Using Entropy-Based Features and Machine Learning Techniques

2023 International Conference on Information and Communication Technology for Sustainable Development (ICICT4SD)

Research paper thumbnail of Supported Erythrocyte Membranes on Piezoelectric Sensors for Studying the Interactions with Nanoparticles

Applications of nanoparticles (NPs) in nanodrugs, food additives, and cosmetics can result in the... more Applications of nanoparticles (NPs) in nanodrugs, food additives, and cosmetics can result in the presence of nanomaterials in human circulatory system and their attachment to red blood cells (RBCs), which may lead to cytotoxic effects. To investigate the interactions of NPs with RBC membranes (RBCm), supported erythrocyte membranes (SRBCm) were developed on the piezoelectric sensors in a quartz crystal microbalance with dissipation (QCM-D) at 25 °C. A well dispersed RBCm suspension at 1 mM NaCl and 0.2 mM NaHCO3 was obtained from whole blood, and comprised of colloidal membrane fragments with the average hydrodynamic diameter and zeta potential as 390 nm and -0.53 mV, respectively, at pH 7.0. The thin and rigid SRBCm was formed mainly through the deposition of RBCm fragments on the poly-L-lysine modified crystal sensor, leading to the average frequency shift of -26.2 Hz and the low ratio of dissipation to frequency shift (7.2 × 10-8 Hz-1). The complete coverage of SRBCm was indicat...

Research paper thumbnail of A 30-day follow-up study on the prevalence of SARS-COV-2 genetic markers in wastewater from the residence of COVID-19 patient and comparison with clinical positivity

Science of The Total Environment

Wastewater Based Epidemiology (WBE) is an important tool to fight against COVID-19 as it provides... more Wastewater Based Epidemiology (WBE) is an important tool to fight against COVID-19 as it provides insights into the health status of the targeted population from a small single house to a large municipality level in a cost-effective, rapid and non-invasive way. The implementation of WBE-based surveillance could reduce the burden on the public health system, management of pandemics, help make informed decisions and protect public health. In this study, a house of COVID-19 patients was targeted for monitoring the prevalence of SARS-CoV-2 genetic markers in wastewater samples (WS) with clinical specimens (CS) over a period of 30 days. RT-qPCR technique was employed to target nonstructural (ORF1ab) and structural-nucleocapsid (N) protein genes of SARS-CoV-2, according to the validated experimental protocol. Physiological, environmental, and biological parameters were also measured following the American Public Health Association (APHA) standard protocol. SARS-CoV-2 viral shedding in wastewater peaked when the highest number of COVID-19 cases were clinically diagnosed. Throughout the study period, 7450 to 23000 gene copies/1000 mL were detected, where we found 47 percent (57/120) positive samples from WS and 35 percent (128/360) from CS. When the COVID-19 patient number was the lowest (2), the highest CT value (39.4; i.e., lowest copy number) was identified from WS. On the other hand, when the COVID-19 patients were the highest (6), the lowest CT value (25.2 i.e., highest copy numbers) was obtained from WS. An increased signal of the SARS-CoV-2 viral load from the COVID-19 patient signal was found in the WS earlier than in CS. Using customized primer sets in a traditional PCR approach, we confirmed that all SARSCoV-2 variants from CS and WS were Delta variants (B.1.617.2). To our knowledge, this is the first follow-up study to determine a relationship between COVID-19 patients and the discharge of SARS-CoV-2 RNA genetic markers in wastewater from a single house including all family members for clinical sampling from a developing country (Bangladesh) without a proper sewage system. The findings of the study indicate that monitoring the genetic markers of the SARSCoV-2 virus in wastewater could identify COVID-19 cases, which reduces the burden on the public health system in COVID-19 pandemics.

Research paper thumbnail of An opinion on Wastewater-Based Epidemiological Monitoring (WBEM) with Clinical Diagnostic Test (CDT) for detecting high-prevalence areas of community COVID-19 infections

Current Opinion in Environmental Science & Health

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Research paper thumbnail of Wastewater-based epidemiological surveillance to monitor the prevalence of SARS-CoV-2 in developing countries with onsite sanitation facilities

Environmental Pollution

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Research paper thumbnail of Wastewater surveillance of SARS-CoV-2 in Bangladesh: Opportunities and challenges

Current Opinion in Environmental Science & Health, 2022

The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is a public health crisis of glob... more The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is a public health crisis of global concern. The progression of the COVID-19 pandemic has been monitored in the first place by testing symptomatic individuals for SARS-CoV-2 virus in the respiratory samples. Concurrently, wastewater carries feces, urine, and sputum that potentially contains SARS-CoV-2 intact virus or partially damaged viral genetic materials excreted by infected individuals. This brings significant opportunities for understanding the infection dynamics by environmental surveillance. It has advantages for the country, especially in densely populated areas where individual clinical testing is difficult. However, there are several challenges including: 1) establishing a sampling plan and schedule that is representative of the various catchment populations 2) development and validation of standardized protocols for the laboratory analysis 3) understanding hydraulic flows and virus transport in complex wastewater drainage systems and 4) collaborative efforts from government agencies, NGOs, public health units and academia.

Research paper thumbnail of Systems Strengthening and Policy Support to Increase Access to Safe Drinking Water

Geological Society of America Abstracts with Programs, 2020

Research paper thumbnail of Revisiting Arsenic Mitigation in Bangladesh for Designing an Integrated Approach for Digital Decision Making to Reduce Exposure Through Drinking Water

Geological Society of America Abstracts with Programs, 2020

Research paper thumbnail of First detection of SARS-CoV-2 genetic material in the vicinity of COVID-19 isolation centre through wastewater surveillance in Bangladesh

ABSTRACTIn the course of a COVID-19 pandemic, 0.33 million people got infected in Bangladesh, we ... more ABSTRACTIn the course of a COVID-19 pandemic, 0.33 million people got infected in Bangladesh, we made the first and successful attempt to detect SARS-CoV-2 viruses’ genetic material in the vicinity wastewaters of an isolation centre i.e. Shaheed Bhulu Stadium, situated at Noakhali. The idea was to understand the genetic loading variation, both temporal and distance-wise in the nearby wastewater drains when the number of infected COVID-19 patients is not varying much. Owing to the fact that isolation center, in general, always contained a constant number of 200 COVID-19 patients, the prime objective of the study was to check if several drains carrying RNA of coronavirus are actually getting diluted or accumulated along with the sewage network. Our finding suggested that while the temporal variation of the genetic load decreased in small drains over the span of 50 days, the main sewer exhibited accumulation of SARS-CoV-2 RNA. Other interesting finding displays that probably distance o...

Research paper thumbnail of Geochemical Mechanisms and Spatio-Temporal Variation of the Mobility of Natural Arsenic in Shallow Groundwater and Surface Water in the Hydrogeologic System of Lower Katari Basin, Bolivian Altiplano

Arsenic (As) contamination of drinking water is a world-wide problem. The natural origin of As, i... more Arsenic (As) contamination of drinking water is a world-wide problem. The natural origin of As, its mobility and transport are of great interest in Bolivian Altiplano due to its presence in mineral ...

Research paper thumbnail of The Role of Digital Transformation in Safe Groundwater Interventions

Research paper thumbnail of ASMITAS – a novel application for digitalizing the SASMIT Sediment Color Tool to identify arsenic safe aquifers for drinking water supplies

Environmental Arsenic in a Changing World, 2019

Research paper thumbnail of Spatial Modelling of Fluoride Contamination in Groundwater Systems in the East African Rift Valley Regions of Northern Tanzania

Research paper thumbnail of Demystifying Sustainable Groundwater System with Big Data: An Integrated Digital Water Platform for Ensuring Drinking Water Safety

Geological Society of America Abstracts with Programs, 2021

Groundwater system is a complex and ambiguous system, often requires detailed understanding of su... more Groundwater system is a complex and ambiguous system, often requires detailed understanding of subsurface geography and hydro-geology for sustainable water supply. In last few decades, dependencies on groundwater for drinking, agriculture and industrial usages have increased manifold. Shallow tubewells have been used for provision of drinking water to a large population in Indian subcontinent. Unfortunately these aquifers are affected by diverse suite of geogenic as well as microbial contaminants which need regular monitoring and proper treatment to meet the health based targets for drinking water supply. A holistic water safety plan ensures safe drinking water to all by effective planning, monitoring and control of water sources. Digital transformation in water sector has been recognized as one of the most important drivers to accelerate and tracking the progress towards SDG 6. Digital technologies are critical to transform the global water systems and help utilities to curb pressing challenges such as water shortage, leakages in water distribution networks, and geogenic and microbial contamination of water. Technologies like Internet of Things (IOT), connected sensors, Artificial Intelligence (AI), Machine Learning (ML), Blockchain and several otheretc. play a pivotal role in enabling the digital transformation in water. Machine learning and deep learning techniques help to develop cognitive solutions and hydrogeological models. We generate huge data pipeline consisting of both primary and secondary data, often referred to as Big data, becoming a soft asset for a country for architecting drinking water safety plan. The digital platform ASMITAS helps to achieve safe groundwater interventions through an aggregation of data system. ASMITAS consists of a data aggregation system for identifying safe sources of water through systematically obtained scientific data from the field and the laboratory. To put it broadly, it is a robust decision system, which uses advanced analytics and Machine Learning (ML). ASMITAS has been successfully deployed in Bangladesh for enhancing private sector capacity and used as decision-making tools for various stakeholders. The platform uses mobile application for collecting key data about lithologs, geospatial information for arsenic and cloud based solution for holistic arsenic risk management. ASMITAS has been successfully integrated with advanced geological modelling tool GeoGIS for aquifer delineation and data visualization.

Research paper thumbnail of Integrated Approach for Effective and Sustainable Arsenic Mitigation Programs with a Digital Decision-Making Tool: Experiences from Three Contrasting Geological Areas of Bangladesh

Geological Society of America Abstracts with Programs, 2021

Research paper thumbnail of Prevalence of SARS-CoV-2 in Communities Through Wastewater Surveillance—a Potential Approach for Estimation of Disease Burden

Current Pollution Reports, 2021

The episodic outbreak of COVID-19 due to SARS-CoV-2 is severely affecting the economy, and the gl... more The episodic outbreak of COVID-19 due to SARS-CoV-2 is severely affecting the economy, and the global count of infected patients is increasing. The actual number of patients had been underestimated due to limited facilities for testing as well as asymptomatic nature of the expression of COVID-19 on individual basis. Tragically, for emerging economies with high population density, the situation has been more complex due to insufficient testing facilities for diagnosis of the disease. However, the recent reports about persistent shedding of viral RNA of SARS-CoV-2 in the human feces have created a possibility to track the prevalence and trends of the disease in communities, known as wastewater-based epidemiology (WBE). In this article, we highlight the current limitations and future prospects for WBE to manage pandemics.

Research paper thumbnail of Wastewater-Based Epidemiology: Global Collaborative to Maximize Contributions in the Fight Against COVID-19

Environmental Science & Technology, 2020

Research paper thumbnail of First detection of SARS-CoV-2 genetic material in the vicinity of COVID-19 isolation Centre in Bangladesh: Variation along the sewer network

Science of The Total Environment, 2021

We made the first and successful attempt to detect SARS-CoV-2 genetic material in the vicinity wa... more We made the first and successful attempt to detect SARS-CoV-2 genetic material in the vicinity wastewaters of an isolation centre i.e. Shaheed Bhulu Stadium, situated at Noakhali. Owing to the fact that isolation centre, in general, always contained a constant number of 200 COVID-19 patients, the prime objective of the study was to check if several drains carrying RNA of coronavirus are actually getting diluted or accumulated along with the sewage network. Our finding suggested that while the temporal variation of the genetic load decreased in small drains over the span of 50 days, the main sewer exhibited accumulation of SARS-CoV-2 RNA. Other interesting finding displays that probably distance of sampling location in meters is not likely to have a significant impact on gene detection concentration, although the quantity of the RNA extracted in the downstream of the drain was higher. These findings are of immense value from the perspective of wastewater surveillance of COVID-19, as they largely imply that we do not need to monitor every wastewater system, and probably major drains monitoring may illustrate the city health. Perhaps, we are reporting the accumulation of SARS-CoV-2 genetic material along with the sewer network i.e. from primary to tertiary drains. The study sought further data collection in this line to simulate conditions prevailed in the most of developing countries and to shed further light on decay/accumulation processes of the genetic load of the SARS-COV-2.

Research paper thumbnail of Effects of Combined Spinal Epidural Anaesthesia and Spinal Anaesthesia on Peri-Operative Pulmonary Status in Geriatric Patients in Lower Extremity Surgery

Journal of Biosciences and Medicines, 2020

Background: Lower extremity surgeries performed in elderly people usually have high prevalence of... more Background: Lower extremity surgeries performed in elderly people usually have high prevalence of peri-operative medical problems related to anaesthesia. The overall objective of peri-operative care of geriatric population is to fast recovery from anaesthesia and avoid functional decline. Objective: To compare the peri-operative pulmonary status of combined spinal epidural anaesthesia (CSEA) and spinal anaesthesia (SA) in geriatric patients underwent lower extremity surgeries. Methods: This prospective comparative study was conducted at Department of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2016 to June 2018. A total of 70 geriatric cases that underwent lower extremity surgeries were included in this study. Cases were randomly allocated into two groups; 35 in Group A (CSEA) and 35 in Group B (SAB). The different outcome variables between the groups like-duration of anaesthesia, respiratory rates (RR), oxygen saturation (SpO 2 ), end tidal CO 2

Research paper thumbnail of Insulin Sensitivity and Insulin Secretion Estimated by Homeostatic Model Assessment (HOMA) in Gestational Diabetes Mellitus

Journal of Biosciences and Medicines, 2020

Research paper thumbnail of Classification of EEG-Based Auditory Evoked Potentials Using Entropy-Based Features and Machine Learning Techniques

2023 International Conference on Information and Communication Technology for Sustainable Development (ICICT4SD)

Research paper thumbnail of Supported Erythrocyte Membranes on Piezoelectric Sensors for Studying the Interactions with Nanoparticles

Applications of nanoparticles (NPs) in nanodrugs, food additives, and cosmetics can result in the... more Applications of nanoparticles (NPs) in nanodrugs, food additives, and cosmetics can result in the presence of nanomaterials in human circulatory system and their attachment to red blood cells (RBCs), which may lead to cytotoxic effects. To investigate the interactions of NPs with RBC membranes (RBCm), supported erythrocyte membranes (SRBCm) were developed on the piezoelectric sensors in a quartz crystal microbalance with dissipation (QCM-D) at 25 °C. A well dispersed RBCm suspension at 1 mM NaCl and 0.2 mM NaHCO3 was obtained from whole blood, and comprised of colloidal membrane fragments with the average hydrodynamic diameter and zeta potential as 390 nm and -0.53 mV, respectively, at pH 7.0. The thin and rigid SRBCm was formed mainly through the deposition of RBCm fragments on the poly-L-lysine modified crystal sensor, leading to the average frequency shift of -26.2 Hz and the low ratio of dissipation to frequency shift (7.2 × 10-8 Hz-1). The complete coverage of SRBCm was indicat...

Research paper thumbnail of A 30-day follow-up study on the prevalence of SARS-COV-2 genetic markers in wastewater from the residence of COVID-19 patient and comparison with clinical positivity

Science of The Total Environment

Wastewater Based Epidemiology (WBE) is an important tool to fight against COVID-19 as it provides... more Wastewater Based Epidemiology (WBE) is an important tool to fight against COVID-19 as it provides insights into the health status of the targeted population from a small single house to a large municipality level in a cost-effective, rapid and non-invasive way. The implementation of WBE-based surveillance could reduce the burden on the public health system, management of pandemics, help make informed decisions and protect public health. In this study, a house of COVID-19 patients was targeted for monitoring the prevalence of SARS-CoV-2 genetic markers in wastewater samples (WS) with clinical specimens (CS) over a period of 30 days. RT-qPCR technique was employed to target nonstructural (ORF1ab) and structural-nucleocapsid (N) protein genes of SARS-CoV-2, according to the validated experimental protocol. Physiological, environmental, and biological parameters were also measured following the American Public Health Association (APHA) standard protocol. SARS-CoV-2 viral shedding in wastewater peaked when the highest number of COVID-19 cases were clinically diagnosed. Throughout the study period, 7450 to 23000 gene copies/1000 mL were detected, where we found 47 percent (57/120) positive samples from WS and 35 percent (128/360) from CS. When the COVID-19 patient number was the lowest (2), the highest CT value (39.4; i.e., lowest copy number) was identified from WS. On the other hand, when the COVID-19 patients were the highest (6), the lowest CT value (25.2 i.e., highest copy numbers) was obtained from WS. An increased signal of the SARS-CoV-2 viral load from the COVID-19 patient signal was found in the WS earlier than in CS. Using customized primer sets in a traditional PCR approach, we confirmed that all SARSCoV-2 variants from CS and WS were Delta variants (B.1.617.2). To our knowledge, this is the first follow-up study to determine a relationship between COVID-19 patients and the discharge of SARS-CoV-2 RNA genetic markers in wastewater from a single house including all family members for clinical sampling from a developing country (Bangladesh) without a proper sewage system. The findings of the study indicate that monitoring the genetic markers of the SARSCoV-2 virus in wastewater could identify COVID-19 cases, which reduces the burden on the public health system in COVID-19 pandemics.

Research paper thumbnail of An opinion on Wastewater-Based Epidemiological Monitoring (WBEM) with Clinical Diagnostic Test (CDT) for detecting high-prevalence areas of community COVID-19 infections

Current Opinion in Environmental Science & Health

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Research paper thumbnail of Wastewater-based epidemiological surveillance to monitor the prevalence of SARS-CoV-2 in developing countries with onsite sanitation facilities

Environmental Pollution

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Research paper thumbnail of Wastewater surveillance of SARS-CoV-2 in Bangladesh: Opportunities and challenges

Current Opinion in Environmental Science & Health, 2022

The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is a public health crisis of glob... more The ongoing pandemic of the coronavirus disease 2019 (COVID-19) is a public health crisis of global concern. The progression of the COVID-19 pandemic has been monitored in the first place by testing symptomatic individuals for SARS-CoV-2 virus in the respiratory samples. Concurrently, wastewater carries feces, urine, and sputum that potentially contains SARS-CoV-2 intact virus or partially damaged viral genetic materials excreted by infected individuals. This brings significant opportunities for understanding the infection dynamics by environmental surveillance. It has advantages for the country, especially in densely populated areas where individual clinical testing is difficult. However, there are several challenges including: 1) establishing a sampling plan and schedule that is representative of the various catchment populations 2) development and validation of standardized protocols for the laboratory analysis 3) understanding hydraulic flows and virus transport in complex wastewater drainage systems and 4) collaborative efforts from government agencies, NGOs, public health units and academia.

Research paper thumbnail of Systems Strengthening and Policy Support to Increase Access to Safe Drinking Water

Geological Society of America Abstracts with Programs, 2020

Research paper thumbnail of Revisiting Arsenic Mitigation in Bangladesh for Designing an Integrated Approach for Digital Decision Making to Reduce Exposure Through Drinking Water

Geological Society of America Abstracts with Programs, 2020

Research paper thumbnail of First detection of SARS-CoV-2 genetic material in the vicinity of COVID-19 isolation centre through wastewater surveillance in Bangladesh

ABSTRACTIn the course of a COVID-19 pandemic, 0.33 million people got infected in Bangladesh, we ... more ABSTRACTIn the course of a COVID-19 pandemic, 0.33 million people got infected in Bangladesh, we made the first and successful attempt to detect SARS-CoV-2 viruses’ genetic material in the vicinity wastewaters of an isolation centre i.e. Shaheed Bhulu Stadium, situated at Noakhali. The idea was to understand the genetic loading variation, both temporal and distance-wise in the nearby wastewater drains when the number of infected COVID-19 patients is not varying much. Owing to the fact that isolation center, in general, always contained a constant number of 200 COVID-19 patients, the prime objective of the study was to check if several drains carrying RNA of coronavirus are actually getting diluted or accumulated along with the sewage network. Our finding suggested that while the temporal variation of the genetic load decreased in small drains over the span of 50 days, the main sewer exhibited accumulation of SARS-CoV-2 RNA. Other interesting finding displays that probably distance o...

Research paper thumbnail of Geochemical Mechanisms and Spatio-Temporal Variation of the Mobility of Natural Arsenic in Shallow Groundwater and Surface Water in the Hydrogeologic System of Lower Katari Basin, Bolivian Altiplano

Arsenic (As) contamination of drinking water is a world-wide problem. The natural origin of As, i... more Arsenic (As) contamination of drinking water is a world-wide problem. The natural origin of As, its mobility and transport are of great interest in Bolivian Altiplano due to its presence in mineral ...

Research paper thumbnail of The Role of Digital Transformation in Safe Groundwater Interventions

Research paper thumbnail of ASMITAS – a novel application for digitalizing the SASMIT Sediment Color Tool to identify arsenic safe aquifers for drinking water supplies

Environmental Arsenic in a Changing World, 2019

Research paper thumbnail of Spatial Modelling of Fluoride Contamination in Groundwater Systems in the East African Rift Valley Regions of Northern Tanzania

Research paper thumbnail of Demystifying Sustainable Groundwater System with Big Data: An Integrated Digital Water Platform for Ensuring Drinking Water Safety

Geological Society of America Abstracts with Programs, 2021

Groundwater system is a complex and ambiguous system, often requires detailed understanding of su... more Groundwater system is a complex and ambiguous system, often requires detailed understanding of subsurface geography and hydro-geology for sustainable water supply. In last few decades, dependencies on groundwater for drinking, agriculture and industrial usages have increased manifold. Shallow tubewells have been used for provision of drinking water to a large population in Indian subcontinent. Unfortunately these aquifers are affected by diverse suite of geogenic as well as microbial contaminants which need regular monitoring and proper treatment to meet the health based targets for drinking water supply. A holistic water safety plan ensures safe drinking water to all by effective planning, monitoring and control of water sources. Digital transformation in water sector has been recognized as one of the most important drivers to accelerate and tracking the progress towards SDG 6. Digital technologies are critical to transform the global water systems and help utilities to curb pressing challenges such as water shortage, leakages in water distribution networks, and geogenic and microbial contamination of water. Technologies like Internet of Things (IOT), connected sensors, Artificial Intelligence (AI), Machine Learning (ML), Blockchain and several otheretc. play a pivotal role in enabling the digital transformation in water. Machine learning and deep learning techniques help to develop cognitive solutions and hydrogeological models. We generate huge data pipeline consisting of both primary and secondary data, often referred to as Big data, becoming a soft asset for a country for architecting drinking water safety plan. The digital platform ASMITAS helps to achieve safe groundwater interventions through an aggregation of data system. ASMITAS consists of a data aggregation system for identifying safe sources of water through systematically obtained scientific data from the field and the laboratory. To put it broadly, it is a robust decision system, which uses advanced analytics and Machine Learning (ML). ASMITAS has been successfully deployed in Bangladesh for enhancing private sector capacity and used as decision-making tools for various stakeholders. The platform uses mobile application for collecting key data about lithologs, geospatial information for arsenic and cloud based solution for holistic arsenic risk management. ASMITAS has been successfully integrated with advanced geological modelling tool GeoGIS for aquifer delineation and data visualization.

Research paper thumbnail of Integrated Approach for Effective and Sustainable Arsenic Mitigation Programs with a Digital Decision-Making Tool: Experiences from Three Contrasting Geological Areas of Bangladesh

Geological Society of America Abstracts with Programs, 2021

Research paper thumbnail of Prevalence of SARS-CoV-2 in Communities Through Wastewater Surveillance—a Potential Approach for Estimation of Disease Burden

Current Pollution Reports, 2021

The episodic outbreak of COVID-19 due to SARS-CoV-2 is severely affecting the economy, and the gl... more The episodic outbreak of COVID-19 due to SARS-CoV-2 is severely affecting the economy, and the global count of infected patients is increasing. The actual number of patients had been underestimated due to limited facilities for testing as well as asymptomatic nature of the expression of COVID-19 on individual basis. Tragically, for emerging economies with high population density, the situation has been more complex due to insufficient testing facilities for diagnosis of the disease. However, the recent reports about persistent shedding of viral RNA of SARS-CoV-2 in the human feces have created a possibility to track the prevalence and trends of the disease in communities, known as wastewater-based epidemiology (WBE). In this article, we highlight the current limitations and future prospects for WBE to manage pandemics.

Research paper thumbnail of Wastewater-Based Epidemiology: Global Collaborative to Maximize Contributions in the Fight Against COVID-19

Environmental Science & Technology, 2020

Research paper thumbnail of First detection of SARS-CoV-2 genetic material in the vicinity of COVID-19 isolation Centre in Bangladesh: Variation along the sewer network

Science of The Total Environment, 2021

We made the first and successful attempt to detect SARS-CoV-2 genetic material in the vicinity wa... more We made the first and successful attempt to detect SARS-CoV-2 genetic material in the vicinity wastewaters of an isolation centre i.e. Shaheed Bhulu Stadium, situated at Noakhali. Owing to the fact that isolation centre, in general, always contained a constant number of 200 COVID-19 patients, the prime objective of the study was to check if several drains carrying RNA of coronavirus are actually getting diluted or accumulated along with the sewage network. Our finding suggested that while the temporal variation of the genetic load decreased in small drains over the span of 50 days, the main sewer exhibited accumulation of SARS-CoV-2 RNA. Other interesting finding displays that probably distance of sampling location in meters is not likely to have a significant impact on gene detection concentration, although the quantity of the RNA extracted in the downstream of the drain was higher. These findings are of immense value from the perspective of wastewater surveillance of COVID-19, as they largely imply that we do not need to monitor every wastewater system, and probably major drains monitoring may illustrate the city health. Perhaps, we are reporting the accumulation of SARS-CoV-2 genetic material along with the sewer network i.e. from primary to tertiary drains. The study sought further data collection in this line to simulate conditions prevailed in the most of developing countries and to shed further light on decay/accumulation processes of the genetic load of the SARS-COV-2.

Research paper thumbnail of Effects of Combined Spinal Epidural Anaesthesia and Spinal Anaesthesia on Peri-Operative Pulmonary Status in Geriatric Patients in Lower Extremity Surgery

Journal of Biosciences and Medicines, 2020

Background: Lower extremity surgeries performed in elderly people usually have high prevalence of... more Background: Lower extremity surgeries performed in elderly people usually have high prevalence of peri-operative medical problems related to anaesthesia. The overall objective of peri-operative care of geriatric population is to fast recovery from anaesthesia and avoid functional decline. Objective: To compare the peri-operative pulmonary status of combined spinal epidural anaesthesia (CSEA) and spinal anaesthesia (SA) in geriatric patients underwent lower extremity surgeries. Methods: This prospective comparative study was conducted at Department of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2016 to June 2018. A total of 70 geriatric cases that underwent lower extremity surgeries were included in this study. Cases were randomly allocated into two groups; 35 in Group A (CSEA) and 35 in Group B (SAB). The different outcome variables between the groups like-duration of anaesthesia, respiratory rates (RR), oxygen saturation (SpO 2 ), end tidal CO 2

Research paper thumbnail of Insulin Sensitivity and Insulin Secretion Estimated by Homeostatic Model Assessment (HOMA) in Gestational Diabetes Mellitus

Journal of Biosciences and Medicines, 2020