Taiwo Solaja - Academia.edu (original) (raw)
Papers by Taiwo Solaja
Babcock University Medical Journal
Background: Ectopic breast tissue (EBT) is an uncommon occurrence in which the breast tissue can ... more Background: Ectopic breast tissue (EBT) is an uncommon occurrence in which the breast tissue can be found at any point along the milk line. Although it is most commonly found on the axilla, it can also present on the thighs, perineum, vulva, inframammary region, and groin. EBT mimicking a Bartholin’s abscess is extremely rare. Case presentation: Here, we report the case of a 31-year-old nulliparous woman who presented to our gynecology clinic with a complaint of right-sided vulvar swelling. An initial diagnosis of Bartholin’s abscess was made after clinical examination. This was surgically removed using marsupialization. However, following histopathological & immuno-histochemical evaluation, a confirmatory diagnosis of ectopic breast tissue was made. Conclusion: Indeed, our case re-emphasizes the absolute need for histopathological examination of every tumor notwithstanding the nature of the presentation, site of occurrence, and/or initial diagnosis. Furthermore, although rare, EBT...
Scholars Journal of Medical Case Reports
Osteolipoma is an extremely rare histologic variant of lipoma. It is sometimes called lipoma with... more Osteolipoma is an extremely rare histologic variant of lipoma. It is sometimes called lipoma with osseous element. It can occur in any part of the body ranging from intracranial cavity to different musculoskeletal regions. We presented a case seen in a 40 years old Nigerian woman with a non-enlarging, non-tender swelling in the right leg just below the knee joint medially. The diagnosis was confirmed by histology after excisional biopsy which examination showed sheets of matured adipocytes traversed into lobules by fibro collagenous strands. Osteolipoma is still relatively rare. However, they are benign and should not be confused with other sinister lesions.
Journal of advances in medicine and medical research, Oct 12, 2022
Deep vein thrombosis is the most frequent Venous thromboembolic event seen among individuals with... more Deep vein thrombosis is the most frequent Venous thromboembolic event seen among individuals with hematological diseases which is associated with high morbidity and mortality. It is associated with various risk factors. It mainly affects the deep veins of the lower extremities and the pelvis. Phlegmasia dolens is an uncommon skin condition associated with or caused by acute deep vein thrombosis and presents in three clinical subtypes such as phlegmasia alba dolens, phlegmasia cerulea dolens, and venous gangrene.
West African journal of medicine, 2020
BACKGROUND Gastric cancer develops from chronic gastritis through distinct precancerous lesions w... more BACKGROUND Gastric cancer develops from chronic gastritis through distinct precancerous lesions which include atrophic gastritis (AG), intestinal metaplasia (IM) and dysplasia in a sequential manner, all of which are related to Helicobacter pylori (H. pylori) infection. We determined the prevalence of H. pylori infection and the gastric premalignant conditions in a Southwestern Nigerian population with chronic gastritis. MATERIALS AND METHODS A prospective cross-sectional study conducted on 252 adult patients with dyspepsia at a faith-based tertiary health facility in Nigeria. Gastroscopy was performed on all the participants and five gastric biopsies were taken from each of them. Standard histological examination for H. pylori, gastritis and the precancerous lesions was performed on the specimens. The biopsy sampling and histological examination were performed in line with the Updated Sydney System recommendations. We summarized data by Means ± Standard Deviation, frequencies and p...
Annual Research & Review in Biology, 2021
Aims: To highlight the pathogenesis of endometrial osseus metaplasia, its importance as a rare ca... more Aims: To highlight the pathogenesis of endometrial osseus metaplasia, its importance as a rare cause of infertility and the benefit of hysteroscopic evaluation of infertile women with risk factors for osseus metaplasia. Presentation of Case: A diagnosis of endometrial osseus metaplasia was confirmed histologically in three women undergoing diagnostic hysteroscopy as part of infertility evaluation. They all had chronic vaginal discharge and a preceding history of induced second trimester abortion. Two of the patients were referred for evaluation before in-vitro-fertilization (IVF). Hysteroscopy was done with a 30° telescope, initially using a 2-channel diagnostic sheath, which was later replaced with a 4-channel operating sheath for tissue retrieval. Discussion: Endometrial osseus metaplasia is a rare condition characterized by the presence of mature or immature bone in the endometrial cavity. Endometrial retention of embryonic tissue following an abortion is the commonest theory of ...
Journal of Advances in Medicine and Medical Research, 2018
Background: Lupus Vulgaris is the most common form of cutaneous tuberculosis. It represents a rea... more Background: Lupus Vulgaris is the most common form of cutaneous tuberculosis. It represents a reactivation of infection in people with moderate to high immunity against mycobacterium tuberculosis. Lesions can develop in all ages, as a collection of discrete, red-brown papules that subsequently coalesce to form an indolent asymptomatic plaque on the affected site. Diagnosis constitutes a major challenge as the most definitive investigative modality, mantoux test is not always positive. Histological examination and initiation of antitubercular therapy usually leads to diagnosis and clinical cure respectively. Objective: We report a case of Lupus Vulgaris of external nose, a rare, underreported and commonly misdiagnosed condition in Nigeria.
Case Reports in Surgery, 2014
Choristoma is development of a normal tissue in an aberrant location. This report describes jejun... more Choristoma is development of a normal tissue in an aberrant location. This report describes jejunal salivary choristoma (JSC) causing recurring episodes of abdominal discomfort in a 5-year-old girl. Exploratory laporatomy revealed a pale yellow subserosal jejunal lesion. Wedge resection of the lesion and repair of the bowel were performed. The child did well postoperatively and has since that time been free of pain at follow-up. Histopathological examination of the resected lesion revealed salivary gland choriostoma. Literature review (PUBMED search engine) revealed no previous report of this rare clinicopathologic entity. We conclude that choriostoma should be considered a possible differential when evaluating abdominal complaint in children.
Case Reports in Medicine, 2022
Introduction. Endometriosis is defined as a chronic gynecologic disease which is characterized by... more Introduction. Endometriosis is defined as a chronic gynecologic disease which is characterized by the presence of endometrial glands and stroma in anatomical sites and organs outside the uterine cavity. The exact prevalence of endometriosis is difficult to determine because many women remain asymptomatic. However, endometriosis affects about 10% to 15% of women. Thoracic endometriosis (TES) is the most common endometriosis outside the abdominopelvic cavity. It refers to endometriosis within the thoracic cavity including the lung parenchyma, diaphragm, and pleural surfaces. It can manifest as catamenial chest pain, pneumothorax, hemoptysis, hemothorax, catamenial haemoptysis, and pulmonary nodules. Case Summary. A 39-years-old married female presented with recurrent right-sided chest pain of 22 years duration, recurrent cough of more than 20 years and progressive breathlessness of a month duration. The chest pain is pleuritic, and it often starts few days to the onset of her menses a...
NIGERIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2021
Background: The long-term outcomes of Helicobacter pylori infection ultimately depend on the dist... more Background: The long-term outcomes of Helicobacter pylori infection ultimately depend on the distribution and extent of gastritis. Three main types of gastritis phenotypes which include pangastritis, antral-predominant gastritis, and corpus-predominant gastritis have been observed. Corpus predominant gastritis is more common in the parts of Asia with a high prevalence of gastric adenocarcinoma. This study was conducted to determine the prevalence of H. pylori-associated gastritis phenotypes in a South-western Nigerian population, a sub-Saharan African population. Materials and Methods: The study was a cross-sectional prospective study which included 267 dyspeptic patients who had esophagogastroduodenoscopy at a tertiary health institution in South-west Nigeria. Five gastric biopsies were taken from each subject, and standard histologic examination was performed on the specimens. Both biopsy sampling and histologic examination followed the Updated Sydney System recommendations. The d...
Pleomorphic salivary adenoma (PSA) is a benign tumor composed of epithelial and mesenchymal eleme... more Pleomorphic salivary adenoma (PSA) is a benign tumor composed of epithelial and mesenchymal elements. Approximately 10% of pleomorphic adenomas occur in the minor salivary glands, with the palate being the most common site. Mesenchymal elements in PSA are capable of giving rise to various components that are usually seen in the tumor. Still, the presence of calcifications either from degenerations or the mesenchymal elements is rare. We are reporting a case of giant pleomorphic adenoma of the soft palate with dystrophic calcification and significant upper aerodigestive obstruction in a 49-year-old Nigerian. Surgical excision was done under general anesthesia via oral route.
Case Reports in Clinical Medicine, 2020
Nigerian journal of clinical practice
Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant ne... more Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant neoplasms with unique epidemiological, pathological, and treatment considerations. Only few studies have been conducted so far on these tumors in Nigeria. This study aims to study in greater detail, the pathological features of these cancers in Nigerian patients. The surgical specimens of patients diagnosed with malignant tumors of the upper aerodigestive tracts in the Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) in Ile-Ife, Nigeria, over a 10-year period, formed the basis of this study. Analysis was done for differences in proportion using the Chi-square test (P is significant at < 0.05) by SPSS version 15. There were a total of 62 cases. The overall mean age was 50.7 years, while the age range was from 3 years to 90 years. The male to female ratio was 3.1:1. A majority of the patients (67.7%) were older than 40 years...
Case Reports in Clinical Medicine
Angiomyolipomas (AML) are benign mesenchymal tumours. It is commonly seen in the kidney. Extra-re... more Angiomyolipomas (AML) are benign mesenchymal tumours. It is commonly seen in the kidney. Extra-renal sites of AML are uncommon though it can occur in any part of the body. Reports of cutaneous AML are rare in the literature. We present a case of an 11-year-old female with a polypoidal swelling on the nose that was noticed a few weeks after birth, which progressively increased in size till it was causing nasal blockage. This cutaneous lesion is different from a renal angiomyolipoma because it lacks features of tuberous sclerosis, non-invasive, absence of epithelioid cells and negative HMB-45 staining. Histopathology shows a mixture of blood vessels, mature adipocytes and smooth muscle. These unique features distinguish this lesion from other possible differentials such as angiomyoma and myolipoma. Histopathology and immunohistochemistry confirm the swelling as angiomyolipoma of the nose. We concluded that histopathology and immunohistochemistry are important diagnostic tools for cutaneous AML irrespective of gender, age of onset and site of lesion.
Nigerian journal of clinical practice
Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant ne... more Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant neoplasms with unique epidemiological, pathological, and treatment considerations. Only few studies have been conducted so far on these tumors in Nigeria. This study aims to study in greater detail, the pathological features of these cancers in Nigerian patients. The surgical specimens of patients diagnosed with malignant tumors of the upper aerodigestive tracts in the Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) in Ile-Ife, Nigeria, over a 10-year period, formed the basis of this study. Analysis was done for differences in proportion using the Chi-square test (P is significant at < 0.05) by SPSS version 15. There were a total of 62 cases. The overall mean age was 50.7 years, while the age range was from 3 years to 90 years. The male to female ratio was 3.1:1. A majority of the patients (67.7%) were older than 40 years...
Babcock University Medical Journal
Background: Ectopic breast tissue (EBT) is an uncommon occurrence in which the breast tissue can ... more Background: Ectopic breast tissue (EBT) is an uncommon occurrence in which the breast tissue can be found at any point along the milk line. Although it is most commonly found on the axilla, it can also present on the thighs, perineum, vulva, inframammary region, and groin. EBT mimicking a Bartholin’s abscess is extremely rare. Case presentation: Here, we report the case of a 31-year-old nulliparous woman who presented to our gynecology clinic with a complaint of right-sided vulvar swelling. An initial diagnosis of Bartholin’s abscess was made after clinical examination. This was surgically removed using marsupialization. However, following histopathological & immuno-histochemical evaluation, a confirmatory diagnosis of ectopic breast tissue was made. Conclusion: Indeed, our case re-emphasizes the absolute need for histopathological examination of every tumor notwithstanding the nature of the presentation, site of occurrence, and/or initial diagnosis. Furthermore, although rare, EBT...
Scholars Journal of Medical Case Reports
Osteolipoma is an extremely rare histologic variant of lipoma. It is sometimes called lipoma with... more Osteolipoma is an extremely rare histologic variant of lipoma. It is sometimes called lipoma with osseous element. It can occur in any part of the body ranging from intracranial cavity to different musculoskeletal regions. We presented a case seen in a 40 years old Nigerian woman with a non-enlarging, non-tender swelling in the right leg just below the knee joint medially. The diagnosis was confirmed by histology after excisional biopsy which examination showed sheets of matured adipocytes traversed into lobules by fibro collagenous strands. Osteolipoma is still relatively rare. However, they are benign and should not be confused with other sinister lesions.
Journal of advances in medicine and medical research, Oct 12, 2022
Deep vein thrombosis is the most frequent Venous thromboembolic event seen among individuals with... more Deep vein thrombosis is the most frequent Venous thromboembolic event seen among individuals with hematological diseases which is associated with high morbidity and mortality. It is associated with various risk factors. It mainly affects the deep veins of the lower extremities and the pelvis. Phlegmasia dolens is an uncommon skin condition associated with or caused by acute deep vein thrombosis and presents in three clinical subtypes such as phlegmasia alba dolens, phlegmasia cerulea dolens, and venous gangrene.
West African journal of medicine, 2020
BACKGROUND Gastric cancer develops from chronic gastritis through distinct precancerous lesions w... more BACKGROUND Gastric cancer develops from chronic gastritis through distinct precancerous lesions which include atrophic gastritis (AG), intestinal metaplasia (IM) and dysplasia in a sequential manner, all of which are related to Helicobacter pylori (H. pylori) infection. We determined the prevalence of H. pylori infection and the gastric premalignant conditions in a Southwestern Nigerian population with chronic gastritis. MATERIALS AND METHODS A prospective cross-sectional study conducted on 252 adult patients with dyspepsia at a faith-based tertiary health facility in Nigeria. Gastroscopy was performed on all the participants and five gastric biopsies were taken from each of them. Standard histological examination for H. pylori, gastritis and the precancerous lesions was performed on the specimens. The biopsy sampling and histological examination were performed in line with the Updated Sydney System recommendations. We summarized data by Means ± Standard Deviation, frequencies and p...
Annual Research & Review in Biology, 2021
Aims: To highlight the pathogenesis of endometrial osseus metaplasia, its importance as a rare ca... more Aims: To highlight the pathogenesis of endometrial osseus metaplasia, its importance as a rare cause of infertility and the benefit of hysteroscopic evaluation of infertile women with risk factors for osseus metaplasia. Presentation of Case: A diagnosis of endometrial osseus metaplasia was confirmed histologically in three women undergoing diagnostic hysteroscopy as part of infertility evaluation. They all had chronic vaginal discharge and a preceding history of induced second trimester abortion. Two of the patients were referred for evaluation before in-vitro-fertilization (IVF). Hysteroscopy was done with a 30° telescope, initially using a 2-channel diagnostic sheath, which was later replaced with a 4-channel operating sheath for tissue retrieval. Discussion: Endometrial osseus metaplasia is a rare condition characterized by the presence of mature or immature bone in the endometrial cavity. Endometrial retention of embryonic tissue following an abortion is the commonest theory of ...
Journal of Advances in Medicine and Medical Research, 2018
Background: Lupus Vulgaris is the most common form of cutaneous tuberculosis. It represents a rea... more Background: Lupus Vulgaris is the most common form of cutaneous tuberculosis. It represents a reactivation of infection in people with moderate to high immunity against mycobacterium tuberculosis. Lesions can develop in all ages, as a collection of discrete, red-brown papules that subsequently coalesce to form an indolent asymptomatic plaque on the affected site. Diagnosis constitutes a major challenge as the most definitive investigative modality, mantoux test is not always positive. Histological examination and initiation of antitubercular therapy usually leads to diagnosis and clinical cure respectively. Objective: We report a case of Lupus Vulgaris of external nose, a rare, underreported and commonly misdiagnosed condition in Nigeria.
Case Reports in Surgery, 2014
Choristoma is development of a normal tissue in an aberrant location. This report describes jejun... more Choristoma is development of a normal tissue in an aberrant location. This report describes jejunal salivary choristoma (JSC) causing recurring episodes of abdominal discomfort in a 5-year-old girl. Exploratory laporatomy revealed a pale yellow subserosal jejunal lesion. Wedge resection of the lesion and repair of the bowel were performed. The child did well postoperatively and has since that time been free of pain at follow-up. Histopathological examination of the resected lesion revealed salivary gland choriostoma. Literature review (PUBMED search engine) revealed no previous report of this rare clinicopathologic entity. We conclude that choriostoma should be considered a possible differential when evaluating abdominal complaint in children.
Case Reports in Medicine, 2022
Introduction. Endometriosis is defined as a chronic gynecologic disease which is characterized by... more Introduction. Endometriosis is defined as a chronic gynecologic disease which is characterized by the presence of endometrial glands and stroma in anatomical sites and organs outside the uterine cavity. The exact prevalence of endometriosis is difficult to determine because many women remain asymptomatic. However, endometriosis affects about 10% to 15% of women. Thoracic endometriosis (TES) is the most common endometriosis outside the abdominopelvic cavity. It refers to endometriosis within the thoracic cavity including the lung parenchyma, diaphragm, and pleural surfaces. It can manifest as catamenial chest pain, pneumothorax, hemoptysis, hemothorax, catamenial haemoptysis, and pulmonary nodules. Case Summary. A 39-years-old married female presented with recurrent right-sided chest pain of 22 years duration, recurrent cough of more than 20 years and progressive breathlessness of a month duration. The chest pain is pleuritic, and it often starts few days to the onset of her menses a...
NIGERIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2021
Background: The long-term outcomes of Helicobacter pylori infection ultimately depend on the dist... more Background: The long-term outcomes of Helicobacter pylori infection ultimately depend on the distribution and extent of gastritis. Three main types of gastritis phenotypes which include pangastritis, antral-predominant gastritis, and corpus-predominant gastritis have been observed. Corpus predominant gastritis is more common in the parts of Asia with a high prevalence of gastric adenocarcinoma. This study was conducted to determine the prevalence of H. pylori-associated gastritis phenotypes in a South-western Nigerian population, a sub-Saharan African population. Materials and Methods: The study was a cross-sectional prospective study which included 267 dyspeptic patients who had esophagogastroduodenoscopy at a tertiary health institution in South-west Nigeria. Five gastric biopsies were taken from each subject, and standard histologic examination was performed on the specimens. Both biopsy sampling and histologic examination followed the Updated Sydney System recommendations. The d...
Pleomorphic salivary adenoma (PSA) is a benign tumor composed of epithelial and mesenchymal eleme... more Pleomorphic salivary adenoma (PSA) is a benign tumor composed of epithelial and mesenchymal elements. Approximately 10% of pleomorphic adenomas occur in the minor salivary glands, with the palate being the most common site. Mesenchymal elements in PSA are capable of giving rise to various components that are usually seen in the tumor. Still, the presence of calcifications either from degenerations or the mesenchymal elements is rare. We are reporting a case of giant pleomorphic adenoma of the soft palate with dystrophic calcification and significant upper aerodigestive obstruction in a 49-year-old Nigerian. Surgical excision was done under general anesthesia via oral route.
Case Reports in Clinical Medicine, 2020
Nigerian journal of clinical practice
Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant ne... more Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant neoplasms with unique epidemiological, pathological, and treatment considerations. Only few studies have been conducted so far on these tumors in Nigeria. This study aims to study in greater detail, the pathological features of these cancers in Nigerian patients. The surgical specimens of patients diagnosed with malignant tumors of the upper aerodigestive tracts in the Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) in Ile-Ife, Nigeria, over a 10-year period, formed the basis of this study. Analysis was done for differences in proportion using the Chi-square test (P is significant at < 0.05) by SPSS version 15. There were a total of 62 cases. The overall mean age was 50.7 years, while the age range was from 3 years to 90 years. The male to female ratio was 3.1:1. A majority of the patients (67.7%) were older than 40 years...
Case Reports in Clinical Medicine
Angiomyolipomas (AML) are benign mesenchymal tumours. It is commonly seen in the kidney. Extra-re... more Angiomyolipomas (AML) are benign mesenchymal tumours. It is commonly seen in the kidney. Extra-renal sites of AML are uncommon though it can occur in any part of the body. Reports of cutaneous AML are rare in the literature. We present a case of an 11-year-old female with a polypoidal swelling on the nose that was noticed a few weeks after birth, which progressively increased in size till it was causing nasal blockage. This cutaneous lesion is different from a renal angiomyolipoma because it lacks features of tuberous sclerosis, non-invasive, absence of epithelioid cells and negative HMB-45 staining. Histopathology shows a mixture of blood vessels, mature adipocytes and smooth muscle. These unique features distinguish this lesion from other possible differentials such as angiomyoma and myolipoma. Histopathology and immunohistochemistry confirm the swelling as angiomyolipoma of the nose. We concluded that histopathology and immunohistochemistry are important diagnostic tools for cutaneous AML irrespective of gender, age of onset and site of lesion.
Nigerian journal of clinical practice
Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant ne... more Cancers of the upper aerodigestive tract constitute a diverse heterogeneous group of malignant neoplasms with unique epidemiological, pathological, and treatment considerations. Only few studies have been conducted so far on these tumors in Nigeria. This study aims to study in greater detail, the pathological features of these cancers in Nigerian patients. The surgical specimens of patients diagnosed with malignant tumors of the upper aerodigestive tracts in the Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) in Ile-Ife, Nigeria, over a 10-year period, formed the basis of this study. Analysis was done for differences in proportion using the Chi-square test (P is significant at < 0.05) by SPSS version 15. There were a total of 62 cases. The overall mean age was 50.7 years, while the age range was from 3 years to 90 years. The male to female ratio was 3.1:1. A majority of the patients (67.7%) were older than 40 years...