Taufik Zain - Academia.edu (original) (raw)
Papers by Taufik Zain
Kepariwisataan: Jurnal Ilmiah, Jan 4, 2022
Pembelajaran anak pada usia sekolah dasar banyak yang kurang menggemari mata pelajaran matematika... more Pembelajaran anak pada usia sekolah dasar banyak yang kurang menggemari mata pelajaran matematika, mereka menganggap pelajaran matematika itu sulit, dikarenakan proses dan metode yang digunakan hanyalah hubungan satu arah yaitu antara guru ke siswa tanpa adanya timbal balik dari siswa ke guru itu sendiri. Hal tersebut menyebabkan anak menjadi pendengar yang pasif sehingga menghambat proses berfikir kreatif matematis seorang anak untuk menyelesaikan permasalahan yang ada dalam pembelajaran matematika. Salah satu hal yang dapat mendorong anak untuk berfikir kreatif matematis adalah dengan penggunaan media ajar yang tepat, salah satunya dengan menggunakan media film elektronik dalam pembelajaran matematika pokok bahasan bangun ruang. Pembelajaran menggunakan media film elektronik dapat mendorong anak untuk berfikir kreatif matematis dengan adanya gambar-gambar yang dapat memancing imajinasi siswa. Dengan demikian pengguanaan media film elektronik diharapkan dapat memberikan pegaruh pos...
Pada kondisi stres, tubuh memberikan respon fisiologis berupa peningkatan kadar kortisol yang dap... more Pada kondisi stres, tubuh memberikan respon fisiologis berupa peningkatan kadar kortisol yang dapat menghambat sekresi pulsatil GnRH sehingga dapat mengganggu siklus menstruasi. Desain penelitian ini adalah cross section dengan mengamati tingkat stres dan durasi siklus menstruasi responden dengan menggunakan kuesioner DASS 42 dan kuesioner tentang menstruasi. Dengan menggunakan teknik simple random sampling pada angkatan 2010, 2011, dan 2012 didapatkan 78 responden, dimana 6 responden dinyatakan masuk kriteria eksklusi sehingga total responden sebanyak 72 responden. Penelitian menunjukkan bahwa dari 15 responden yang mengalami stres, 3 responden mengalami oligomenorrhea, 12 responden mengalami menstruasi yang normal. Uji hipotesis somers�d menunjukkan p value = 0,559 r = 0,064 arah korelasi positif (+) sehingga dapat disimpulkan bahwa tidak terdapat korelasi antara tingkat stres dan pola menstruas
Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017), 2017
The rate of maternal and infant mortality are still high in Indonesia, one of the causes is the h... more The rate of maternal and infant mortality are still high in Indonesia, one of the causes is the high rate of low birth weight. There are many etiology of low birth weight, and most of them are preventable if pregnant women do antenatal care (ANC) during pregnancy. Aim of this research is to determine the knowledge, attitudes and behavior of pregnant woman at East Ciputat Public Health Center (Puskesmas) about ANC to take care their pregnancy until birth. Experimental design with pretest and posttest study type. The research was conducted in polyclinic of mother and child Health in East Ciputat Puskesmas, Pamulang, South Tangerang during August 2016. The population are pregnant woman who control to Puskesmas Ciputat Timur in August 2016. The total sample are 31 respondents, with consecutive sampling and analyze by Wilcoxon. Result: The results after we give individual counseling, we have been getting a decline of the respondents who have low knowledge 22.6%, increasing of the respondents that have moderate knowledge 3.2%, and 19.4% for the increasing of the respondents with high knowledge. We have 31 respondents with positive attitude which is increase 16.1%. We got decreasing 19.4% respondents who have negative behavior, and increasing 19.4% respondents who have positive behavior. The "P" value for the knowledge, attitude and behavior is 0.002 ; 0.000 ; 0.002. This shows that the individual counseling to the respondents is meaningful.
Much of what we know about how our sensory systems operate comes from studying aftereffects. Prol... more Much of what we know about how our sensory systems operate comes from studying aftereffects. Prolonged and repeated exposure to a constant stimulus (adaptation) can impact responses to subsequent test stimuli, compared to a non-adapted test stimulus. Researchers often infer, based on changes to response patterns, that sensory encoding has been changed by adaptation. However, it can be ambiguous whether a given aftereffect changes sensory encoding, decision processes, or both. We propose that confidence estimates can be used as a diagnostic tool to identify whether aftereffects arise either partially or entirely from post-perceptual processes. In three experiments, we demonstrate the utility of confidence judgements in determining whether an aftereffect results from sensory or criterion changes. Given the simplicity of our approach, this tool could readily be applied to resolve contemporary controversies regarding the origins of aftereffects and the penetration of perception by cogni...
Protein tyrosine phosphatases (PTPs) regulate the phosphorylation state of many important signali... more Protein tyrosine phosphatases (PTPs) regulate the phosphorylation state of many important signaling molecules and are increasingly viewed as integral components of signal transduction cascades. PTPs have been implicated in the development of type 2 diabetes, breast cancer and neurodegenerative disorders, and thus have been extensively explored as a potential therapeutic target. This thesis explores the functional components required for engineering novel modalities to successfully target protein tyrosine phosphatase 1B (PTP1B), the most well studied member of the large family of PTPs. In the first part of this thesis, a screen of a library of compounds identified potent salicylic acid inhibitors with promising single digit micromolar activity. In silico computational analysis drove the design and synthesis of a second generation of disalicylic acid inhibitors, and new, more selective and potent inhibitors have been identified. The second part of this thessis explores the first ever application of artificially induced protein-membrane anchors designed to target PTPs. iii Contributions of Authors The work described within this dissertation has been reported in two peer-reviewed publications. The introduction is an original composition. Chapters 2, and 3 are based heavily on my published or in preparation manuscripts. The final chapter consists of my own concluding thoughts and reflections.
Kepariwisataan: Jurnal Ilmiah, Jan 4, 2022
Pembelajaran anak pada usia sekolah dasar banyak yang kurang menggemari mata pelajaran matematika... more Pembelajaran anak pada usia sekolah dasar banyak yang kurang menggemari mata pelajaran matematika, mereka menganggap pelajaran matematika itu sulit, dikarenakan proses dan metode yang digunakan hanyalah hubungan satu arah yaitu antara guru ke siswa tanpa adanya timbal balik dari siswa ke guru itu sendiri. Hal tersebut menyebabkan anak menjadi pendengar yang pasif sehingga menghambat proses berfikir kreatif matematis seorang anak untuk menyelesaikan permasalahan yang ada dalam pembelajaran matematika. Salah satu hal yang dapat mendorong anak untuk berfikir kreatif matematis adalah dengan penggunaan media ajar yang tepat, salah satunya dengan menggunakan media film elektronik dalam pembelajaran matematika pokok bahasan bangun ruang. Pembelajaran menggunakan media film elektronik dapat mendorong anak untuk berfikir kreatif matematis dengan adanya gambar-gambar yang dapat memancing imajinasi siswa. Dengan demikian pengguanaan media film elektronik diharapkan dapat memberikan pegaruh pos...
Pada kondisi stres, tubuh memberikan respon fisiologis berupa peningkatan kadar kortisol yang dap... more Pada kondisi stres, tubuh memberikan respon fisiologis berupa peningkatan kadar kortisol yang dapat menghambat sekresi pulsatil GnRH sehingga dapat mengganggu siklus menstruasi. Desain penelitian ini adalah cross section dengan mengamati tingkat stres dan durasi siklus menstruasi responden dengan menggunakan kuesioner DASS 42 dan kuesioner tentang menstruasi. Dengan menggunakan teknik simple random sampling pada angkatan 2010, 2011, dan 2012 didapatkan 78 responden, dimana 6 responden dinyatakan masuk kriteria eksklusi sehingga total responden sebanyak 72 responden. Penelitian menunjukkan bahwa dari 15 responden yang mengalami stres, 3 responden mengalami oligomenorrhea, 12 responden mengalami menstruasi yang normal. Uji hipotesis somers�d menunjukkan p value = 0,559 r = 0,064 arah korelasi positif (+) sehingga dapat disimpulkan bahwa tidak terdapat korelasi antara tingkat stres dan pola menstruas
Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017), 2017
The rate of maternal and infant mortality are still high in Indonesia, one of the causes is the h... more The rate of maternal and infant mortality are still high in Indonesia, one of the causes is the high rate of low birth weight. There are many etiology of low birth weight, and most of them are preventable if pregnant women do antenatal care (ANC) during pregnancy. Aim of this research is to determine the knowledge, attitudes and behavior of pregnant woman at East Ciputat Public Health Center (Puskesmas) about ANC to take care their pregnancy until birth. Experimental design with pretest and posttest study type. The research was conducted in polyclinic of mother and child Health in East Ciputat Puskesmas, Pamulang, South Tangerang during August 2016. The population are pregnant woman who control to Puskesmas Ciputat Timur in August 2016. The total sample are 31 respondents, with consecutive sampling and analyze by Wilcoxon. Result: The results after we give individual counseling, we have been getting a decline of the respondents who have low knowledge 22.6%, increasing of the respondents that have moderate knowledge 3.2%, and 19.4% for the increasing of the respondents with high knowledge. We have 31 respondents with positive attitude which is increase 16.1%. We got decreasing 19.4% respondents who have negative behavior, and increasing 19.4% respondents who have positive behavior. The "P" value for the knowledge, attitude and behavior is 0.002 ; 0.000 ; 0.002. This shows that the individual counseling to the respondents is meaningful.
Much of what we know about how our sensory systems operate comes from studying aftereffects. Prol... more Much of what we know about how our sensory systems operate comes from studying aftereffects. Prolonged and repeated exposure to a constant stimulus (adaptation) can impact responses to subsequent test stimuli, compared to a non-adapted test stimulus. Researchers often infer, based on changes to response patterns, that sensory encoding has been changed by adaptation. However, it can be ambiguous whether a given aftereffect changes sensory encoding, decision processes, or both. We propose that confidence estimates can be used as a diagnostic tool to identify whether aftereffects arise either partially or entirely from post-perceptual processes. In three experiments, we demonstrate the utility of confidence judgements in determining whether an aftereffect results from sensory or criterion changes. Given the simplicity of our approach, this tool could readily be applied to resolve contemporary controversies regarding the origins of aftereffects and the penetration of perception by cogni...
Protein tyrosine phosphatases (PTPs) regulate the phosphorylation state of many important signali... more Protein tyrosine phosphatases (PTPs) regulate the phosphorylation state of many important signaling molecules and are increasingly viewed as integral components of signal transduction cascades. PTPs have been implicated in the development of type 2 diabetes, breast cancer and neurodegenerative disorders, and thus have been extensively explored as a potential therapeutic target. This thesis explores the functional components required for engineering novel modalities to successfully target protein tyrosine phosphatase 1B (PTP1B), the most well studied member of the large family of PTPs. In the first part of this thesis, a screen of a library of compounds identified potent salicylic acid inhibitors with promising single digit micromolar activity. In silico computational analysis drove the design and synthesis of a second generation of disalicylic acid inhibitors, and new, more selective and potent inhibitors have been identified. The second part of this thessis explores the first ever application of artificially induced protein-membrane anchors designed to target PTPs. iii Contributions of Authors The work described within this dissertation has been reported in two peer-reviewed publications. The introduction is an original composition. Chapters 2, and 3 are based heavily on my published or in preparation manuscripts. The final chapter consists of my own concluding thoughts and reflections.