Thomas Murry - Academia.edu (original) (raw)
Papers by Thomas Murry
Journal of Voice, 2017
High-speed videoendoscopy captures the cycle-to-cycle vibratory motion of each individual vocal f... more High-speed videoendoscopy captures the cycle-to-cycle vibratory motion of each individual vocal fold in normal and severely disordered phonation. Therefore, it provides a direct method to examine the specific vibratory changes following vocal fold surgery. The purpose of this study was to examine the vocal fold vibratory pattern changes in the surgically treated pathologic vocal fold and the contralateral vocal fold in three vocal pathologies: vocal polyp (n = 3), paresis or paralysis (n = 3), and scar (n = 3). Digital kymography was used to extract high-speed kymographic vocal fold images at the mid-membranous region of the vocal fold. Spectral analysis was subsequently applied to the digital kymography to quantify the cycle-to-cycle movements of each vocal fold, expressed as a spectrum. Surgical modification resulted in significantly improved spectral power of the treated pathologic vocal fold. Furthermore, the contralateral vocal fold also presented with improved spectral power irrespective of vocal pathology. In comparison with normal vocal fold spectrum, postsurgical vocal fold vibrations continued to demonstrate decreased vibratory amplitude in both vocal folds.
Journal of Voice, 2012
To examine the perceptual structure of voice attributes in adductor spasmodic dysphonia (ADSD) be... more To examine the perceptual structure of voice attributes in adductor spasmodic dysphonia (ADSD) before and after botulinum toxin treatment and identify acoustic correlates of underlying perceptual factors. Reliability of perceptual judgments is considered in detail. Pre- and posttreatment trial with comparison to healthy controls, using single-blind randomized listener judgments of voice qualities, as well as retrospective comparison with acoustic measurements. Oral readings were recorded from 42 ADSD speakers before and after treatment as well as from their age- and sex-matched controls. Experienced judges listened to speech samples and rated attributes of overall voice quality, breathiness, roughness, and brokenness, using computer-implemented visual analog scaling. Data were adjusted for regression to the mean and submitted to principal components factor analysis. Acoustic waveforms, extracted from the reading samples, were analyzed and measurements correlated with perceptual factor scores. Four reliable perceptual variables of ADSD voice were effectively reduced to two underlying factors that corresponded to hyperadduction, most strongly associated with roughness, and hypoadduction, most strongly associated with breathiness. After treatment, the hyperadduction factor improved, whereas the hypoadduction factor worsened. Statistically significant (P<0.01) correlations were observed between perceived roughness and four acoustic measures, whereas breathiness correlated with aperiodicity and cepstral peak prominence (CPPs). This study supported a two-factor model of ADSD, suggesting perceptual characterization by both hyperadduction and hypoadduction before and after treatment. Responses of the factors to treatment were consistent with previous research. Correlations among perceptual and acoustic variables suggested that multiple acoustic features contributed to the overall impression of roughness. Although CPPs appears to be a partial correlate of perceived breathiness, a physical basis of this percept remained less clear.
JAMA otolaryngology-- head & neck surgery, Jan 17, 2018
An aging population experiences an increase in age-related problems, such as presbyphonia. The ca... more An aging population experiences an increase in age-related problems, such as presbyphonia. The causes of pathologic presbyphonia are incompletely understood. To determine what distinguishes pathologic presbyphonia from presbylaryngis. This was a cohort study at an outpatient otolaryngology subspecialty clinic of a tertiary academic referral center. Participants were consecutive consenting adults older than 74 years without laryngeal pathologic abnormalities who visited the clinic as participants or companions. Patient questionnaires, otolaryngologic, video stroboscopic, and voice examinations were compiled. Patients were divided into groups based on whether they endorsed a voice complaint. Three blinded authors graded stroboscopic examinations for findings consistent with presbylaryngis (vocal fold bowing, vocal process prominence, glottic insufficiency). Voice Handicap Index-10, Reflux Symptom Index, Cough Severity Index, Dyspnea Index, Singing Voice Handicap Index-10 , Eating Asse...
…, 1996
K. Thomas Robbins, MD; James Fontanesi, MD; Frank SH Wong, MD; Daniel Vicario, MD; Stephen Seagre... more K. Thomas Robbins, MD; James Fontanesi, MD; Frank SH Wong, MD; Daniel Vicario, MD; Stephen Seagren, MD; Parvesh Kumar, MD; Robert Weisman, MD; Phillip Pellitteri, DO; J. Randal Thomas, MD; Pamela Flick, MD; Robert Palmer, MD; AlvaWeir III, MD; Charles Kerber, ...
Journal of Voice, 1998
Simultaneous measurements of mean airflow rate, vocal intensity and fundamental frequency were ma... more Simultaneous measurements of mean airflow rate, vocal intensity and fundamental frequency were made during flexible video endoscopic recording of the vowel /i/ sustained in two vocal registers, modal and falsetto. The glottal closure patterns of four males and four females were evaluated by visually inspecting the video images. Acoustic signals were recorded and analyzed to verify the frequency and intensity criteria. Aerodynamic analysis of mean airflow rate was done via Rothenberg mask and commercial software. Incomplete glottic closure was common in both males and females. The degree of closure was significantly higher for modal samples than for falsetto samples with frequency and intensity held constant. The shape of the glottal closure did not vary with changes in the mode of phonation. As expected, the mean airflow rate increased with decreased glottal closure. The results suggest that incomplete glottic closure should be considered as a normal glottal configuration in high frequency modal and falsetto phonation. Moreover, hourglass and spindle glottal configurations may also be found in both the modal and falsetto registers of normal subjects. These results also confirm the positive relationships between degree of glottal gap and mean airflow rate. Thus, mean airflow rate may be regarded as a criterion for judging degree of glottal closure.
Infant Behav Develop, 1986
... It would appear that further tests on reception mode incorporating such variables as range, d... more ... It would appear that further tests on reception mode incorporating such variables as range, depth, and speed of the ships are necessary to generalize to more operating conditions than those tested in the study. (Author). ... URI: http://archive.rubicon-foundation.org/8699. Date: 1971. ...
European Archives of Oto Rhino Laryngology Official Journal of the European Federation of Oto Rhino Laryngological Societies Affiliated With the German Society For Oto Rhino Laryngology Head and Neck Surgery, Jun 9, 2010
Journal of Speech Language and Hearing Research, 1966
A spoken language sample of 50 sentences was obtained from 30 normal and 30 hearing-impaired chil... more A spoken language sample of 50 sentences was obtained from 30 normal and 30 hearing-impaired children and quantified according to total output and syntactical accuracy. A total score of structural accuracy (syntax) was obtained by combining the errors of addition, ...
Journal of Voice, 2017
High-speed videoendoscopy captures the cycle-to-cycle vibratory motion of each individual vocal f... more High-speed videoendoscopy captures the cycle-to-cycle vibratory motion of each individual vocal fold in normal and severely disordered phonation. Therefore, it provides a direct method to examine the specific vibratory changes following vocal fold surgery. The purpose of this study was to examine the vocal fold vibratory pattern changes in the surgically treated pathologic vocal fold and the contralateral vocal fold in three vocal pathologies: vocal polyp (n = 3), paresis or paralysis (n = 3), and scar (n = 3). Digital kymography was used to extract high-speed kymographic vocal fold images at the mid-membranous region of the vocal fold. Spectral analysis was subsequently applied to the digital kymography to quantify the cycle-to-cycle movements of each vocal fold, expressed as a spectrum. Surgical modification resulted in significantly improved spectral power of the treated pathologic vocal fold. Furthermore, the contralateral vocal fold also presented with improved spectral power irrespective of vocal pathology. In comparison with normal vocal fold spectrum, postsurgical vocal fold vibrations continued to demonstrate decreased vibratory amplitude in both vocal folds.
Journal of Voice, 2012
To examine the perceptual structure of voice attributes in adductor spasmodic dysphonia (ADSD) be... more To examine the perceptual structure of voice attributes in adductor spasmodic dysphonia (ADSD) before and after botulinum toxin treatment and identify acoustic correlates of underlying perceptual factors. Reliability of perceptual judgments is considered in detail. Pre- and posttreatment trial with comparison to healthy controls, using single-blind randomized listener judgments of voice qualities, as well as retrospective comparison with acoustic measurements. Oral readings were recorded from 42 ADSD speakers before and after treatment as well as from their age- and sex-matched controls. Experienced judges listened to speech samples and rated attributes of overall voice quality, breathiness, roughness, and brokenness, using computer-implemented visual analog scaling. Data were adjusted for regression to the mean and submitted to principal components factor analysis. Acoustic waveforms, extracted from the reading samples, were analyzed and measurements correlated with perceptual factor scores. Four reliable perceptual variables of ADSD voice were effectively reduced to two underlying factors that corresponded to hyperadduction, most strongly associated with roughness, and hypoadduction, most strongly associated with breathiness. After treatment, the hyperadduction factor improved, whereas the hypoadduction factor worsened. Statistically significant (P<0.01) correlations were observed between perceived roughness and four acoustic measures, whereas breathiness correlated with aperiodicity and cepstral peak prominence (CPPs). This study supported a two-factor model of ADSD, suggesting perceptual characterization by both hyperadduction and hypoadduction before and after treatment. Responses of the factors to treatment were consistent with previous research. Correlations among perceptual and acoustic variables suggested that multiple acoustic features contributed to the overall impression of roughness. Although CPPs appears to be a partial correlate of perceived breathiness, a physical basis of this percept remained less clear.
JAMA otolaryngology-- head & neck surgery, Jan 17, 2018
An aging population experiences an increase in age-related problems, such as presbyphonia. The ca... more An aging population experiences an increase in age-related problems, such as presbyphonia. The causes of pathologic presbyphonia are incompletely understood. To determine what distinguishes pathologic presbyphonia from presbylaryngis. This was a cohort study at an outpatient otolaryngology subspecialty clinic of a tertiary academic referral center. Participants were consecutive consenting adults older than 74 years without laryngeal pathologic abnormalities who visited the clinic as participants or companions. Patient questionnaires, otolaryngologic, video stroboscopic, and voice examinations were compiled. Patients were divided into groups based on whether they endorsed a voice complaint. Three blinded authors graded stroboscopic examinations for findings consistent with presbylaryngis (vocal fold bowing, vocal process prominence, glottic insufficiency). Voice Handicap Index-10, Reflux Symptom Index, Cough Severity Index, Dyspnea Index, Singing Voice Handicap Index-10 , Eating Asse...
…, 1996
K. Thomas Robbins, MD; James Fontanesi, MD; Frank SH Wong, MD; Daniel Vicario, MD; Stephen Seagre... more K. Thomas Robbins, MD; James Fontanesi, MD; Frank SH Wong, MD; Daniel Vicario, MD; Stephen Seagren, MD; Parvesh Kumar, MD; Robert Weisman, MD; Phillip Pellitteri, DO; J. Randal Thomas, MD; Pamela Flick, MD; Robert Palmer, MD; AlvaWeir III, MD; Charles Kerber, ...
Journal of Voice, 1998
Simultaneous measurements of mean airflow rate, vocal intensity and fundamental frequency were ma... more Simultaneous measurements of mean airflow rate, vocal intensity and fundamental frequency were made during flexible video endoscopic recording of the vowel /i/ sustained in two vocal registers, modal and falsetto. The glottal closure patterns of four males and four females were evaluated by visually inspecting the video images. Acoustic signals were recorded and analyzed to verify the frequency and intensity criteria. Aerodynamic analysis of mean airflow rate was done via Rothenberg mask and commercial software. Incomplete glottic closure was common in both males and females. The degree of closure was significantly higher for modal samples than for falsetto samples with frequency and intensity held constant. The shape of the glottal closure did not vary with changes in the mode of phonation. As expected, the mean airflow rate increased with decreased glottal closure. The results suggest that incomplete glottic closure should be considered as a normal glottal configuration in high frequency modal and falsetto phonation. Moreover, hourglass and spindle glottal configurations may also be found in both the modal and falsetto registers of normal subjects. These results also confirm the positive relationships between degree of glottal gap and mean airflow rate. Thus, mean airflow rate may be regarded as a criterion for judging degree of glottal closure.
Infant Behav Develop, 1986
... It would appear that further tests on reception mode incorporating such variables as range, d... more ... It would appear that further tests on reception mode incorporating such variables as range, depth, and speed of the ships are necessary to generalize to more operating conditions than those tested in the study. (Author). ... URI: http://archive.rubicon-foundation.org/8699. Date: 1971. ...
European Archives of Oto Rhino Laryngology Official Journal of the European Federation of Oto Rhino Laryngological Societies Affiliated With the German Society For Oto Rhino Laryngology Head and Neck Surgery, Jun 9, 2010
Journal of Speech Language and Hearing Research, 1966
A spoken language sample of 50 sentences was obtained from 30 normal and 30 hearing-impaired chil... more A spoken language sample of 50 sentences was obtained from 30 normal and 30 hearing-impaired children and quantified according to total output and syntactical accuracy. A total score of structural accuracy (syntax) was obtained by combining the errors of addition, ...