Tim Christofides - Profile on Academia.edu (original) (raw)
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Istituto Dermopatico dell'Immacolata (IDI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)
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Papers by Tim Christofides
The Internet Journal of Plastic Surgery, 2006
Morpheic basal cell carcinomas (BCC) are considered aggressive and difficult to control. Can prio... more Morpheic basal cell carcinomas (BCC) are considered aggressive and difficult to control. Can prior treatment of a regular BCC initiate its change to a morpheic pattern? 36 patients with diagnosed morpheic BCC were selected. Details of previous surgery and histologic diagnosis were recorded. Out of the 36 patients only 11 had morpheic BCC without previous treatment. Of the 21 who had had prior treatment, 9 had previous histological results available, of which only 1 had an original diagnosis of morpheic BCC. The study prompts the following questions: 1. After treatment can a BCC transform into a more aggressive morpheic type? 2. Can a background of fibrosis such as that produced by freezing, curetting or that seen with chronic wounds initiate a change in the character of the basal cell to the morpheic form to allow its survival in the scar tissue?
The Internet Journal of Plastic Surgery, 2006
Morpheic basal cell carcinomas (BCC) are considered aggressive and difficult to control. Can prio... more Morpheic basal cell carcinomas (BCC) are considered aggressive and difficult to control. Can prior treatment of a regular BCC initiate its change to a morpheic pattern? 36 patients with diagnosed morpheic BCC were selected. Details of previous surgery and histologic diagnosis were recorded. Out of the 36 patients only 11 had morpheic BCC without previous treatment. Of the 21 who had had prior treatment, 9 had previous histological results available, of which only 1 had an original diagnosis of morpheic BCC. The study prompts the following questions: 1. After treatment can a BCC transform into a more aggressive morpheic type? 2. Can a background of fibrosis such as that produced by freezing, curetting or that seen with chronic wounds initiate a change in the character of the basal cell to the morpheic form to allow its survival in the scar tissue?