Timothy W. Abraham - Academia.edu (original) (raw)
Papers by Timothy W. Abraham
Journal of Medicinal Chemistry, 1996
Nucleosides, Nucleotides & Nucleic Acids, Oct 1, 1997
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La presente invention concerne un procede permettant d'hydrogener l'acide 3-hydroxypropio... more La presente invention concerne un procede permettant d'hydrogener l'acide 3-hydroxypropionique, ou certains de ses esters, voire encore des melanges de l'acide et de l'ester, dans une phase liquide, en presence d'un catalyseur au ruthenium. Ce catalyseur au ruthenium s'utilise seul ou en association avec au moins un autre catalyseur metallique. En l'occurrence, l'autre catalyseur est le molybdene, le tungstene, le titane le zirconium, le niobium, le vanadium, le chrome, ou certains de leurs melanges.
L'invention concerne une composition de revetement de liberation a base d'amidon et des p... more L'invention concerne une composition de revetement de liberation a base d'amidon et des procedes de preparation de celle-ci.
L'invention concerne une cire contenant de la metathese et/ou un produit similaire, au moins ... more L'invention concerne une cire contenant de la metathese et/ou un produit similaire, au moins en partie, un produit pouvant etre forme a partir d'une reaction de metathese. La cire peut etre utilisee afin de former des articles, par exemple, des bougies (des bougies conteneurs, des bougies parfumees et/ou des bougies cylindriques), des crayons, des buches ou des tartes. La cire comprend habituellement d'autres composants ajoutes a la metathese.
L'invention concerne un produit de reaction issu de la co-deshydratation d'un sucre-alcoo... more L'invention concerne un produit de reaction issu de la co-deshydratation d'un sucre-alcool et d'un polyol de reactif ayant une fonctionnalite hydroxyle moyenne en nombre inferieure a 4,0. Selon certains aspects, le sucre-alcool comprend le mannitol, le sorbitol, le xylitol, l'erythritol ou des melanges de ceux-ci. Selon certains aspects preferes, le sucre-alcool comprend le sorbitol. Dans certains aspects, le polyol de reactif a un poids moleculaire moyen compris entre 40 et 500 Daltons. Selon certains aspects, le produit de reaction peut etre approprie a la fabrication de mousse de polyisocyanurate. Selon certains aspects, le produit de reaction peut etre melange a des polyols de diluant, tels que des diols, des glycols, l'ethylene glycol, le diethylene glycol, le dipropylene glycol, le propylene glycol, le polyethylene glycol, le polypropylene glycol et des melanges de ceux-ci.
L'invention concerne un procede pour modifier chimiquement une composition de depart comporta... more L'invention concerne un procede pour modifier chimiquement une composition de depart comportant : des composes d'alcene polyinsatures afin de convertir au moins une partie des composes d'alcene polyinsatures en des composes d'alcene fonctionnalises monoinsatures. Les composes d'alcene monoinsatures separes peuvent etre utiles, par exemple, en tant que matiere premiere dans la synthese de produits chimiques organiques tels que des diacides, des diesters, et autres produits similaires.
Polymer Science: A Comprehensive Reference, 2012
Lipids are key components of biosystems. Their use is also widespread in industry, consumer produ... more Lipids are key components of biosystems. Their use is also widespread in industry, consumer products, personal care, and in the food and pharmaceutical industries. We find natural waxes such as carnauba wax in car polishes, in lipsticks and eyeliners, as waterproof for leather products, as release and anticaking agents in baked and processed food, and as tablet-coating agents in the pharmaceutical industry. Soybean oil is one of the world’s most widely used edible oils. It is frequently found in margarine and shortenings, mayonnaise, salad dressings, and frozen foods. Nutritionists and chefs alike consider olive oil as essential to the Mediterranean diet as the sun is to the Mediterranean seascape. Sweet almond oil is used as a carrier oil for aromatherapy, as an emollient in skin care and massage therapy, and as a moisturizer for superfatting of soaps. Soy lecithin provides good pigment wetting, and has been well known as a dispersant and antisettling agent for inorganic pigments in alkyd paints. Fatty acids and fatty alcohols provide the basis for biodegradable surfactants and emulsifiers in detergents, cosmetics, agrochemicals, and industrial applications such as paints, adhesives, and inks. Fatty acid esters are used as green solvents, plasticizers, lubricants, and coalescents. However, certain lipids, particularly vegetable oils, are also wonderful renewable raw materials for polymers. Autoxidation and polymer film formation of drying oils were, chemically speaking, at the origin of medieval oil paintings. Epoxidation, epoxy ring opening, ene reaction, hydroformylation, carboxylation, ozonolysis, dimerization, and metathesis are some of the reaction mechanisms generating building blocks for polymers that are useful as coatings, adhesives, inks, plastics, and composites. The increasing importance of fatty acid methyl ester (FAME) as a biofuel has turned glycerin from a specialty to a commodity, opening new opportunities for low-molecular-weight starters for polymers.
Process for the production of monatin, which comprises converting tryptophan and / or indole-3-la... more Process for the production of monatin, which comprises converting tryptophan and / or indole-3-lactic acid into monatin, in which the method comprises: (a) contacting tryptophan or indole-3-lactic acid with a first polypeptide, wherein, when tryptophan is in contact with the first polypeptide, the first polypeptide is selected from tryptophan aminotransferase (EC 2.6.1.27), tryptophan dehydrogenase (EC 1.4.1.19), tyrosine aminotransferase (aromatic) (EC 2.6.1.5 ), tryptophan-phenylpyruvate transaminase (EC 2.6.1.28), multiple substrate aminotransferase (EC 2.6.1.-), aspartate aminotransferase (EC 2.6.1.1), tryptophan oxidase, L-amino acid oxidase (EC 1.4.3.2), D- amino acid dehydrogenase (EC 1.4.99.1), D-amino acid oxidase (EC 1.4.3.3), D-tryptophan aminotransferase, D-alanine aminotransferase (EC 2.6.1.21), glutamate dehydrogenase (EC 1.4.1.2-4), phenylalanine dehydrogenase ( CE 1.4.1.20), or a combination thereof, in which When the indole-3-lactic acid is contacted with the first ...
Process for the production of monatin, which comprises converting tryptophan and / or indole-3-la... more Process for the production of monatin, which comprises converting tryptophan and / or indole-3-lactic acid into monatin, in which the method comprises: (a) contacting tryptophan or indole-3-lactic acid with a first polypeptide, wherein, when tryptophan is in contact with the first polypeptide, the first polypeptide is selected from tryptophan aminotransferase (EC 2.6.1.27), tryptophan dehydrogenase (EC 1.4.1.19), tyrosine aminotransferase (aromatic) (EC 2.6.1.5 ), tryptophan-phenylpyruvate transaminase (EC 2.6.1.28), multiple substrate aminotransferase (EC 2.6.1.-), aspartate aminotransferase (EC 2.6.1.1), tryptophan oxidase, L-amino acid oxidase (EC 1.4.3.2), D- amino acid dehydrogenase (EC 1.4.99.1), D-amino acid oxidase (EC 1.4.3.3), D-tryptophan aminotransferase, D-alanine aminotransferase (EC 2.6.1.21), glutamate dehydrogenase (EC 1.4.1.2-4), phenylalanine dehydrogenase ( CE 1.4.1.20), or a combination thereof, in which When the indole-3-lactic acid is contacted with the first ...
A process is disclosed for conversion of salts of .beta.-hydroxy carbonyl compounds forming usefu... more A process is disclosed for conversion of salts of .beta.-hydroxy carbonyl compounds forming useful conversion products including, e.g., .alpha.,.beta.-unsaturated carbonyl compounds and/or salts of .alpha.,.beta.-unsaturated carbonyl compounds. Conversion products find use, e.g., as feedstock and/or end-use chemicals.
Journal of Medicinal Chemistry, 1996
Nucleosides, Nucleotides & Nucleic Acids, Oct 1, 1997
RefDoc Bienvenue - Welcome. Refdoc est un service / is powered by. ...
La presente invention concerne un procede permettant d'hydrogener l'acide 3-hydroxypropio... more La presente invention concerne un procede permettant d'hydrogener l'acide 3-hydroxypropionique, ou certains de ses esters, voire encore des melanges de l'acide et de l'ester, dans une phase liquide, en presence d'un catalyseur au ruthenium. Ce catalyseur au ruthenium s'utilise seul ou en association avec au moins un autre catalyseur metallique. En l'occurrence, l'autre catalyseur est le molybdene, le tungstene, le titane le zirconium, le niobium, le vanadium, le chrome, ou certains de leurs melanges.
L'invention concerne une composition de revetement de liberation a base d'amidon et des p... more L'invention concerne une composition de revetement de liberation a base d'amidon et des procedes de preparation de celle-ci.
L'invention concerne une cire contenant de la metathese et/ou un produit similaire, au moins ... more L'invention concerne une cire contenant de la metathese et/ou un produit similaire, au moins en partie, un produit pouvant etre forme a partir d'une reaction de metathese. La cire peut etre utilisee afin de former des articles, par exemple, des bougies (des bougies conteneurs, des bougies parfumees et/ou des bougies cylindriques), des crayons, des buches ou des tartes. La cire comprend habituellement d'autres composants ajoutes a la metathese.
L'invention concerne un produit de reaction issu de la co-deshydratation d'un sucre-alcoo... more L'invention concerne un produit de reaction issu de la co-deshydratation d'un sucre-alcool et d'un polyol de reactif ayant une fonctionnalite hydroxyle moyenne en nombre inferieure a 4,0. Selon certains aspects, le sucre-alcool comprend le mannitol, le sorbitol, le xylitol, l'erythritol ou des melanges de ceux-ci. Selon certains aspects preferes, le sucre-alcool comprend le sorbitol. Dans certains aspects, le polyol de reactif a un poids moleculaire moyen compris entre 40 et 500 Daltons. Selon certains aspects, le produit de reaction peut etre approprie a la fabrication de mousse de polyisocyanurate. Selon certains aspects, le produit de reaction peut etre melange a des polyols de diluant, tels que des diols, des glycols, l'ethylene glycol, le diethylene glycol, le dipropylene glycol, le propylene glycol, le polyethylene glycol, le polypropylene glycol et des melanges de ceux-ci.
L'invention concerne un procede pour modifier chimiquement une composition de depart comporta... more L'invention concerne un procede pour modifier chimiquement une composition de depart comportant : des composes d'alcene polyinsatures afin de convertir au moins une partie des composes d'alcene polyinsatures en des composes d'alcene fonctionnalises monoinsatures. Les composes d'alcene monoinsatures separes peuvent etre utiles, par exemple, en tant que matiere premiere dans la synthese de produits chimiques organiques tels que des diacides, des diesters, et autres produits similaires.
Polymer Science: A Comprehensive Reference, 2012
Lipids are key components of biosystems. Their use is also widespread in industry, consumer produ... more Lipids are key components of biosystems. Their use is also widespread in industry, consumer products, personal care, and in the food and pharmaceutical industries. We find natural waxes such as carnauba wax in car polishes, in lipsticks and eyeliners, as waterproof for leather products, as release and anticaking agents in baked and processed food, and as tablet-coating agents in the pharmaceutical industry. Soybean oil is one of the world’s most widely used edible oils. It is frequently found in margarine and shortenings, mayonnaise, salad dressings, and frozen foods. Nutritionists and chefs alike consider olive oil as essential to the Mediterranean diet as the sun is to the Mediterranean seascape. Sweet almond oil is used as a carrier oil for aromatherapy, as an emollient in skin care and massage therapy, and as a moisturizer for superfatting of soaps. Soy lecithin provides good pigment wetting, and has been well known as a dispersant and antisettling agent for inorganic pigments in alkyd paints. Fatty acids and fatty alcohols provide the basis for biodegradable surfactants and emulsifiers in detergents, cosmetics, agrochemicals, and industrial applications such as paints, adhesives, and inks. Fatty acid esters are used as green solvents, plasticizers, lubricants, and coalescents. However, certain lipids, particularly vegetable oils, are also wonderful renewable raw materials for polymers. Autoxidation and polymer film formation of drying oils were, chemically speaking, at the origin of medieval oil paintings. Epoxidation, epoxy ring opening, ene reaction, hydroformylation, carboxylation, ozonolysis, dimerization, and metathesis are some of the reaction mechanisms generating building blocks for polymers that are useful as coatings, adhesives, inks, plastics, and composites. The increasing importance of fatty acid methyl ester (FAME) as a biofuel has turned glycerin from a specialty to a commodity, opening new opportunities for low-molecular-weight starters for polymers.
Process for the production of monatin, which comprises converting tryptophan and / or indole-3-la... more Process for the production of monatin, which comprises converting tryptophan and / or indole-3-lactic acid into monatin, in which the method comprises: (a) contacting tryptophan or indole-3-lactic acid with a first polypeptide, wherein, when tryptophan is in contact with the first polypeptide, the first polypeptide is selected from tryptophan aminotransferase (EC 2.6.1.27), tryptophan dehydrogenase (EC 1.4.1.19), tyrosine aminotransferase (aromatic) (EC 2.6.1.5 ), tryptophan-phenylpyruvate transaminase (EC 2.6.1.28), multiple substrate aminotransferase (EC 2.6.1.-), aspartate aminotransferase (EC 2.6.1.1), tryptophan oxidase, L-amino acid oxidase (EC 1.4.3.2), D- amino acid dehydrogenase (EC 1.4.99.1), D-amino acid oxidase (EC 1.4.3.3), D-tryptophan aminotransferase, D-alanine aminotransferase (EC 2.6.1.21), glutamate dehydrogenase (EC 1.4.1.2-4), phenylalanine dehydrogenase ( CE 1.4.1.20), or a combination thereof, in which When the indole-3-lactic acid is contacted with the first ...
Process for the production of monatin, which comprises converting tryptophan and / or indole-3-la... more Process for the production of monatin, which comprises converting tryptophan and / or indole-3-lactic acid into monatin, in which the method comprises: (a) contacting tryptophan or indole-3-lactic acid with a first polypeptide, wherein, when tryptophan is in contact with the first polypeptide, the first polypeptide is selected from tryptophan aminotransferase (EC 2.6.1.27), tryptophan dehydrogenase (EC 1.4.1.19), tyrosine aminotransferase (aromatic) (EC 2.6.1.5 ), tryptophan-phenylpyruvate transaminase (EC 2.6.1.28), multiple substrate aminotransferase (EC 2.6.1.-), aspartate aminotransferase (EC 2.6.1.1), tryptophan oxidase, L-amino acid oxidase (EC 1.4.3.2), D- amino acid dehydrogenase (EC 1.4.99.1), D-amino acid oxidase (EC 1.4.3.3), D-tryptophan aminotransferase, D-alanine aminotransferase (EC 2.6.1.21), glutamate dehydrogenase (EC 1.4.1.2-4), phenylalanine dehydrogenase ( CE 1.4.1.20), or a combination thereof, in which When the indole-3-lactic acid is contacted with the first ...
A process is disclosed for conversion of salts of .beta.-hydroxy carbonyl compounds forming usefu... more A process is disclosed for conversion of salts of .beta.-hydroxy carbonyl compounds forming useful conversion products including, e.g., .alpha.,.beta.-unsaturated carbonyl compounds and/or salts of .alpha.,.beta.-unsaturated carbonyl compounds. Conversion products find use, e.g., as feedstock and/or end-use chemicals.