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Papers by Levent Tokucoglu

Research paper thumbnail of Seroprevalence of Hepatitits B, Hepatitits C, HIV and Syphilis infections among non-injecting drug users

Anatolian Journal of Psychiatry, 2015

Background: While injection drug use is clearly a significant risk factor for the acquisition of ... more Background: While injection drug use is clearly a significant risk factor for the acquisition of certain infectious diseases, non-injection drug users (NIDUs) may also have higher risk than the general population, due to their involvement in risky behaviors. This study aimed to examine the prevalence of anti-HIV, anti-HCV, and HBsAg and VDRL seropositivity among a sample of non-injecting drug users. Methods: Medical records of the drug users who attended to our psychiatry clinics between April 2010 and April 2011 were reviewed and 55 non-injecting drug users without a previous history of intravenous drug use were identified. Anti-HIV, anti-HCV, HBs-Ag and VDRL assay results have been extracted and seroprevalence rates were calculated. Results: All but one NIDUs were male (n=54; 98.2%); 28 (50.9%) were between 15 and 25 years of age. Serologically, only one patient (a heroin user) was tested positive for HBsAg (1.8%) and one patient (a heroin user) was anti-HCV positive. None of the patients screened for anti-HIV or VDRL were tested positive. Conclusions: This study found low seropositivity rates for HBV, HBC, HIV and VDRL among a group of NIDUs, which might be related to the cultural characteristics of the region.

Research paper thumbnail of Klinik Opiyat Yoksunluk Ölçeği Türkçe Sürümünün Güvenilirlik ve Geçerliliği Reliability and Validity of the Turkish Version of the Clinical Opiate Withdrawal Scale

Noropsikiyatri Arsivi

The aim of the present study was to perform reliability and validity analyses of the Turkish vers... more The aim of the present study was to perform reliability and validity analyses of the Turkish version of the Clinical Opiate Withdrawal Scale which is used to determine the severity of opiate withdrawal. Methods: Initially, the Clinical Opiate Withdrawal Scale (COWS) was translated into Turkish and subsequently back-translated into English. The originality of the back-translated version was approved by the author who developed the scale. After the translation was completed, the scale was used to assess the withdrawal symptoms of 100 patients with opiate withdrawal and 41 patients with alcohol withdrawal. Cronbach' s alpha was used in the reliability assessment; explanatory and confirmatory factor analyses were used in structural validity assessment; and in scale validity, ROC analysis was used among diagnosis groups. Results: The Cronbach' s alpha internal consistency coefficient was calculated as 0.74 in reliability analyses. The correlation coefficient was found to be 0.975 (p<0.001) for inter-rater reliability. Factor analysis was conducted for the structural validity of the scale and findings that support the unidimensional structure of the scale were observed. In the confirmatory factor analysis, CFI, GFI and RMSEA values were found to be 0.905, 0.905 and 0.079, respectively. It was detected that COWS was successful in distinguishing between opiate and alcohol withdrawal symptoms and the area under the ROC curve was 0.878. Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly for assessing opiate withdrawal.

Research paper thumbnail of Addiction is a brain diseaseThat is true, but is that all it is?

Bagımlılık Dergisi Journal of Dependence, 2015

Research paper thumbnail of Klinik Opiyat Yoksunluk Ölçeği (Clinical Opiate Withdrawal Scale-COWS) Türkçe Sürümünün Güvenilirliği ve Geçerliliği

Nöro Psikiyatri Arşivi, 2014

Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly f... more Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly for assessing opiate withdrawal.

Research paper thumbnail of Seroprevalence of Hepatitits B, Hepatitits C, HIV and Syphilis infections among non-injecting drug users

Anatolian Journal of Psychiatry, 2015

Background: While injection drug use is clearly a significant risk factor for the acquisition of ... more Background: While injection drug use is clearly a significant risk factor for the acquisition of certain infectious diseases, non-injection drug users (NIDUs) may also have higher risk than the general population, due to their involvement in risky behaviors. This study aimed to examine the prevalence of anti-HIV, anti-HCV, and HBsAg and VDRL seropositivity among a sample of non-injecting drug users. Methods: Medical records of the drug users who attended to our psychiatry clinics between April 2010 and April 2011 were reviewed and 55 non-injecting drug users without a previous history of intravenous drug use were identified. Anti-HIV, anti-HCV, HBs-Ag and VDRL assay results have been extracted and seroprevalence rates were calculated. Results: All but one NIDUs were male (n=54; 98.2%); 28 (50.9%) were between 15 and 25 years of age. Serologically, only one patient (a heroin user) was tested positive for HBsAg (1.8%) and one patient (a heroin user) was anti-HCV positive. None of the patients screened for anti-HIV or VDRL were tested positive. Conclusions: This study found low seropositivity rates for HBV, HBC, HIV and VDRL among a group of NIDUs, which might be related to the cultural characteristics of the region.

Research paper thumbnail of Klinik Opiyat Yoksunluk Ölçeği Türkçe Sürümünün Güvenilirlik ve Geçerliliği Reliability and Validity of the Turkish Version of the Clinical Opiate Withdrawal Scale

Noropsikiyatri Arsivi

The aim of the present study was to perform reliability and validity analyses of the Turkish vers... more The aim of the present study was to perform reliability and validity analyses of the Turkish version of the Clinical Opiate Withdrawal Scale which is used to determine the severity of opiate withdrawal. Methods: Initially, the Clinical Opiate Withdrawal Scale (COWS) was translated into Turkish and subsequently back-translated into English. The originality of the back-translated version was approved by the author who developed the scale. After the translation was completed, the scale was used to assess the withdrawal symptoms of 100 patients with opiate withdrawal and 41 patients with alcohol withdrawal. Cronbach' s alpha was used in the reliability assessment; explanatory and confirmatory factor analyses were used in structural validity assessment; and in scale validity, ROC analysis was used among diagnosis groups. Results: The Cronbach' s alpha internal consistency coefficient was calculated as 0.74 in reliability analyses. The correlation coefficient was found to be 0.975 (p<0.001) for inter-rater reliability. Factor analysis was conducted for the structural validity of the scale and findings that support the unidimensional structure of the scale were observed. In the confirmatory factor analysis, CFI, GFI and RMSEA values were found to be 0.905, 0.905 and 0.079, respectively. It was detected that COWS was successful in distinguishing between opiate and alcohol withdrawal symptoms and the area under the ROC curve was 0.878. Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly for assessing opiate withdrawal.

Research paper thumbnail of Addiction is a brain diseaseThat is true, but is that all it is?

Bagımlılık Dergisi Journal of Dependence, 2015

Research paper thumbnail of Klinik Opiyat Yoksunluk Ölçeği (Clinical Opiate Withdrawal Scale-COWS) Türkçe Sürümünün Güvenilirliği ve Geçerliliği

Nöro Psikiyatri Arşivi, 2014

Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly f... more Conclusion: This study showed that the Turkish version of COWS can be used reliably and validly for assessing opiate withdrawal.

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