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Research paper thumbnail of Observations on Attenuation of Local Electrogram Amplitude and Circuit Impedance During Atrial Radiofrequency Ablation: An In vivo Investigation Using a Novel Direct Endocardial Visualization Catheter

Journal of Cardiovascular Electrophysiology, 2015

Radiofrequency Ablation with Visual Ablation CatheterAimsTo define the temporal characteristics o... more Radiofrequency Ablation with Visual Ablation CatheterAimsTo define the temporal characteristics of atrial lesion growth (lesion surface area), local electrogram amplitude attenuation, and circuit impedance decrement during in vivo radiofrequency (RF) ablation with direct endocardial visualization (DEV).Methods and ResultsA direct endocardial visualization catheter was used for real‐time endoscopic visualization of atrial endocardial surface during RF ablation. Videos of lesion growth (surface area), circuit impedance, and local electrogram amplitude were recorded during ablation in 11 ovine. Fifty‐two atrial ablations at 12 W, 14 W, and 16 W power for 30 seconds were analyzed. During 30‐second RF ablation, the lesion matured (90% of final lesion dimension) in the first 23.0 ± 5.8 seconds. The local electrogram amplitude attenuation (80% decrement) and circuit impedance attenuation (20% decrement from initial) occurred 13.8 ± 8.2 seconds and 13.1 ± 7.9 seconds, respectively, before l...

Research paper thumbnail of Observations on Attenuation of Local Electrogram Amplitude and Circuit Impedance During Atrial Radiofrequency Ablation: An In vivo Investigation Using a Novel Direct Endocardial Visualization Catheter

Journal of Cardiovascular Electrophysiology, 2015

Radiofrequency Ablation with Visual Ablation CatheterAimsTo define the temporal characteristics o... more Radiofrequency Ablation with Visual Ablation CatheterAimsTo define the temporal characteristics of atrial lesion growth (lesion surface area), local electrogram amplitude attenuation, and circuit impedance decrement during in vivo radiofrequency (RF) ablation with direct endocardial visualization (DEV).Methods and ResultsA direct endocardial visualization catheter was used for real‐time endoscopic visualization of atrial endocardial surface during RF ablation. Videos of lesion growth (surface area), circuit impedance, and local electrogram amplitude were recorded during ablation in 11 ovine. Fifty‐two atrial ablations at 12 W, 14 W, and 16 W power for 30 seconds were analyzed. During 30‐second RF ablation, the lesion matured (90% of final lesion dimension) in the first 23.0 ± 5.8 seconds. The local electrogram amplitude attenuation (80% decrement) and circuit impedance attenuation (20% decrement from initial) occurred 13.8 ± 8.2 seconds and 13.1 ± 7.9 seconds, respectively, before l...

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