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Tristan Clay

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Research paper thumbnail of Preparative production of an enantiomeric pair by engineered polyketide synthases

Chemical Communications, 2021

Modules from the pikromycin synthase were recombined into engineered synthases that furnish an en... more Modules from the pikromycin synthase were recombined into engineered synthases that furnish an enantiomeric pair of 2-stereocenter triketide lactones at >99% ee with yields up to 0.39 g per liter of E. coli K207-3 in shake flasks.

Research paper thumbnail of Preparative production of an enantiomeric pair by engineered polyketide synthases

Chemical Communications, 2021

Modules from the pikromycin synthase were recombined into engineered synthases that furnish an en... more Modules from the pikromycin synthase were recombined into engineered synthases that furnish an enantiomeric pair of 2-stereocenter triketide lactones at >99% ee with yields up to 0.39 g per liter of E. coli K207-3 in shake flasks.

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