Unal Erkorkmaz - Academia.edu (original) (raw)
Papers by Unal Erkorkmaz
Turkish Journal of Medical Sciences
To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monox... more To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monoxide (eCO) and hair nicotine (HN) and to evaluate the relationship between these values. Materials and methods: Included in the study were 96 subjects (64 male, 32 female) divided into 3 groups. Th e subjects in Group 1 (n = 46) were current smokers, and the subjects in Group 2 (n = 20) and Group 3 (n = 30) were nonsmokers with or without environmental TS exposure, respectively. Th e eCO level of all of the subjects was measured with a breath CO monitor. Gas chromatography/mass spectrometry were used for quantifi cation of the HN (n = 47). Results: Th e mean age of the subjects was 39.1 years. Th e mean levels of eCO were 9.3 ppm, 1.3 ppm, and 1.0 ppm and the mean HN concentrations were 20.9 ng/mg, 2.1 ng/mg, and 0.7 ng/mg in the 3 groups, respectively. Th ere was a signifi cant diff erence between Group 1 and the other groups according to the levels of eCO and HN concentrations, but the levels of eCO and HN concentrations were similar in Group 2 and Group 3. Th ere was a positive correlation between the levels of eCO and the HN concentrations. Th e cutoff values of eCO and HN for smokers were 6 ppm and 4 ng/mg, respectively. Conclusion: Although nicotine analysis in some biological samples like hair is specifi c to TS exposure, these methods are expensive and diffi cult procedures. Our results suggest that instead of HN analysis, a cheap and easy method like eCO measurement may be used, but further studies with more cases are needed.
Turkish Journal of Medical Sciences
To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine ... more To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic conjunctivitis was provoked by a mast cell activator (compound 48/80) in 31 New Zealand rabbits. The rabbits were divided into 3 groups, and 1% CAPE, 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate were instilled 30 min before and 15 min after the provocation. The edema and hyperemia in the experimental (right) eyes and control (left) eyes were scored in each group. Anterior segment photographs and conjunctival samples for histopathological evaluation and scoring were taken. Results: When the edema and hyperemia scores of the postprovocation term were compared with those of the provocation term, a significant difference was detected in each group (P = 0.021, P = 0.037, P = 0.0001). The histopathological scores of the provocation and postprovocation terms were evaluated; a statistically significant difference was found in the CAPE and dexamethasone sodium phosphate groups (P = 0.003, P = 0.014), but not in the olopatadine group (P = 0.096). Conclusion: This study demonstrated that 1% CAPE was as clinically efficacious as 0.1% olopatadine and 0.1% dexamethasone. Thus, 1% CAPE may be an alternative to 0.1% olopatadine and 0.1% dexamethasone in the management of acute allergic reactions.
BackgroundAcute appendicitis is the most common non-gynecological emergency during pregnancy. The... more BackgroundAcute appendicitis is the most common non-gynecological emergency during pregnancy. The diagnosis of appendicitis during pregnancy is challenging due to both physiological and laboratory changes. As such, the surgeon needs additional guidance, other than imaging methods, before deciding a surgical intervention. Various scoring methods have been defined and evaluated for the diagnosis of acute appendicitis for a long time. There is no definition of a score for the gestation period, and the comparison of the currently applied scoring methods during the gestation period is not available in the literature.The purpose of our study is to evaluate the efficacy of the most popular scoring systems applied in the diagnosis of acute appendicitis in pregnancy and the tips for introduction to a scoring method for the pregnancy period.MethodsThis single-center retrospective study consists of 79 pregnant patients who were admitted to the emergency department with abdominal pain between M...
JPMA. The Journal of the Pakistan Medical Association, 2017
To assess whether the Iowa Infant Feeding Attitude Scale is a valid and reliable scale for Turkis... more To assess whether the Iowa Infant Feeding Attitude Scale is a valid and reliable scale for Turkish mothers, and to assess maternal attitudes toward various aspects of infant feeding. This methodological, analytical study was conducted at the obstetrics and gynaecology department of Sakarya Training and Research Hospital, Sakarya, Turkey, from June to August 2015, and comprised mothers of newborn babies. Data was collected using the Turkish version of Iowa Infant Feeding Attitude Scale. SPSS 23 was used for data analysis. There were 391 participants in the study. Five items of the original Iowa Infant Feeding Attitude Scale were excluded due to the low correlation with the scale integrity (Cronbach's alpha=0.67). The total mean score of the mothers was 48.11±6.57. A statistically significant difference was found between the educational status, having social security, what the mothers having other children fed these children in the first 6 months and family types (p=0.05 each). Si...
Cumhuriyet Medical Journal, 2017
The aim of the study was to compare nasal mucosal vasodilation induced by two different anestheti... more The aim of the study was to compare nasal mucosal vasodilation induced by two different anesthetic used to provide controlled hypotension with the aid of acoustic rhinometry (AR). Method: This study is prospective randomized clinical study. Fifty patients were randomized into propofol (Group P; n=25) and sevoflurane (Group S; n=25) groups. During anesthesia induction, Group P received propofol (2 mg kg-1 IV) and Group S was administered sevoflurane at a minimal alveolar concentration of 6-8%. Anesthesia was maintained with propofol (4 mg kg h-1) in Group P and 2% sevoflurane in Group S. Both groups received the analgesic remifentanil at a dose of 0.025 µg kg min-1. Patients were performed nasal acoustic rhinometry (AR) measurements. Anesthetic doses were adjusted so as to ensure intraoperative hypotension by maintaining mean arterial pressure at 20-25% lower than the baseline value. Results: In both groups, a significant difference was detected between AR and nasal minimal cross-sectional areas (MCA) measurements taken from the patients in the supine position, both during the preoperative period and at 30 minutes after the induction of anesthesia, but a meaningful decrease in MCA1 and MCA2 values after the induction of anesthesia was observed for both groups. In addition, differences in measurements taken before and after the induction of anesthesia were greater in amplitude for the sevoflurane group versus the propofol group. Conclusions: Controlled hypotension induced using sevoflurane anesthesia might result in higher degrees of vasodilation relative to propofol anesthesia.
South African Medical Journal, 2012
Cumhuriyet Medical Journal, 2014
Aim. Q fever, which is a zoonosis caused by Coxiella burnetii, may result in abortions in infecte... more Aim. Q fever, which is a zoonosis caused by Coxiella burnetii, may result in abortions in infected animals and pregnant women. In our study, we searched the association between Q fever serology and abortion in a region where Q fever is endemic. Method. This study was conducted in Gaziosmanpaşa University Hospital between March and May 2012. A total of 100 women, from these, 64 had a history of spontaneus abortion (cases) and 36 had live births with no complicated obstetrics history or complicated partum (controls), enrolled in the study. Both groups were compared according to where they live, underlying diseases, contact with farm animals or pets and village connectivity. Results. IgG seroprevalence of Coxiella in our study group with the history of abortion was 15.6%, and 11.1% in the control group (p>0.05). When case and control groups were compared, the frequency of inhabitants of the village (p=0.012), subjects who had contact with farm animals [p=0.026, especially cattle (p=0.013)] or domestic animals (p=0.018) in case group were more common than the control group. When all the samples were analyzed, it was seen that the only significant variable affecting Coxiella IgG seropositivity was residency in rural area or visiting rural area (p=0.018). Conclusions. We have found that the relation between abortion and Q fever infection was not statistically significant. On this issue, multicenter studies which have the higher number of samples are needed in our country.
Sakarya Medical Journal, 2015
Objective: Aim of this study is to analyze the change of the area under the adjusted ROC (AdjROC)... more Objective: Aim of this study is to analyze the change of the area under the adjusted ROC (AdjROC) curve in certain conditions via binormal distribution model using simulation studies and application of this algorithm to real data. Materials and Methods: Data sets simulated according to various conditions. PSA and age values of 125 patients who were examined prostate biopsy with pre-diagnosis of prostate cancer in Gaziosmanpasa University Faculty of Medicine Department of Urology at the years of 2005 to 2007. An algorithm and code program was written that make simulation according to various condition using PROC IML procedure in SAS statistical software.Results: According to the simulation study, if biomarker indicators in healthy group are constant and are lower or equal in healthy group than/to disease group, both adjusted AUC (AdjAUC) and AUC have small values and, no significant difference was found between them. The AUC was significantly larger when the biomarker indicators in disease group were higher. In addition, if the correlation between the covariate and biomarker is high in disease group and if AUC is approximately 0.75, then there is significant difference between adjusted AUC and AUC. PSA (Prostate Specific Antigen), a biomarker used for prostate cancer diagnosis, was analyzed based on the adjustments by age. It was found that adjusted AUC value was higher than unadjusted AUC value. Conclusions: For the adjusted ROC model being applicable, covariate and biomarker distributions must show double binormal distribution. If the biomarker can distinguish disease and healthy individuals correctly, then covariate is not needed. If correlation of healthy is approaching to 0 and correlation of disease is 0.50, and if AUC is less than 0.75, then covariate must be included in the model. Model does not work well when sample size of disease and healthy are less than 50.
Nutrición hospitalaria
Eating style is one of the prominente factors that determine energy intake. One of the influencin... more Eating style is one of the prominente factors that determine energy intake. One of the influencing factors that determine parental feeding style is parental perception of the weight status of the child. The aim of this study is to evaluate the relationship between maternal visual perception of their children's weight status and their feeding style. A cross-sectional survey was completed with only mother's of 380 preschool children with age of 5 to 7 (6.14 years). Visual perception scores were measured with a sketch and maternal feeding style was measured with validated "Parental Feeding Style Questionnaire". The parental feeding dimensions "emotional feeding" and "encouragement to eat" subscale scores were low in overweight children according to visual perception classification. "Emotional feeding" and "permissive control" subscale scores were statistically different in children classified as correctly perceived and incorrect...
Iranian journal of arthropod-borne diseases, 2009
The World health Organization (WHO) declares Crimean Congo hemorrhagic fever (CCHF) endemic in Tu... more The World health Organization (WHO) declares Crimean Congo hemorrhagic fever (CCHF) endemic in Turkey. Despite the magnitude of problem, no documented evidence exists in Turkey, which reveals the awareness and practices of the country's adult population regarding CCHF, its spread, symptoms, treatment, and prevention. This study was conducted to assess the level of knowledge, attitudes, and practices regarding CCHF in people visiting tertiary care hospital in Tokat, Turkey. This questionnaire based cross-sectional survey was conducted among patients' relatives or guardians who admitted pediatric outpatient clinics during May-July 2008. The questionnaire was composed of 25 questions. A total of 1034 respondents participated in the survey. Sufficient knowledge about CCHF was not found in 28.9% of the sample. Literate individuals were relatively better informed about CCHF as compared to the illiterate people. Television and radio were considered as the most important and useful ...
![Research paper thumbnail of [Analysis of risk factors in anti-HCV positive patients in Gaziosmanpasa University Hospital, Tokat, Turkey]](https://attachments.academia-assets.com/92699709/thumbnails/1.jpg)
](Mikrobiyoloji bülteni, 2008
Transmission routes and seroprevalence of hepatitis C virus (HCV) may vary between countries and ... more Transmission routes and seroprevalence of hepatitis C virus (HCV) may vary between countries and geographic regions. In this study, we aimed to investigate the risk factors associated with the transmission of HCV in our region, Tokat (located at middle Black Sea region of Turkey). Ninety-seven patients (age range: 16- 78-years-old, mean age: 53.6 +/- 10 yrs; 15 male, 82 female) who were admitted to Infectious Diseases Clinics between September 2004 and February 2007 and found to be anti-HCV positive by microparticle enzyme immunoassay (Abbott, Axsym) were enrolled in this study. The patients were evaluated for the risk factors including blood transfusion, past surgery, medical abortion, dental therapy, history of endoscopy/bronchoscopy, intravenous (i.v.) drug use, hospitalization exceeding one week and hemodialysis. "Sexual contact with multiple partners" has not been evaluated as a risk factor since the sociocultural features of this specific region would possibly preven...
ÖZET Amaç: Bu ça lış ma mı zın ama cı, su bak ro mi yal sı kış ma sen dro mu (SSS) ta nı sı ko na... more ÖZET Amaç: Bu ça lış ma mı zın ama cı, su bak ro mi yal sı kış ma sen dro mu (SSS) ta nı sı ko nan has ta lar da pe lo id uy gu la ma la rı nı içe ren bal ne o te ra pi nin ağ rı ve fonk si yo nel du rum üze rin de ki et ki le ri ni de ğer len dir mek tir. Gereç ve Yöntemler: Kli nik ve rad yo lo jik ola rak su bak ro mi al sı kış ma sen dro mu ta nı sı alan ve ya kın ma sü re si en az üç ay olan 29 has ta ça lış ma ya alın dı. Has ta la rı mı zın or ta la ma ya şı 48.24 ± 6.83 (33-60) yıl olup, 23’ü ka dın ve altısı er kek idi. Uy gu la dı ğı mız pe lo id, 45°C sı cak lı ğın da ve 30 da ki ka sü re ile gün de bir se ans lo kal pe lo id pa ket tar zın da uy gu lan dı. Te da vi ye haf ta içi beş gün ola rak 15 se ans de vam edil di. Ağ rı nın şid de ti ni de ğer len dir mek için Gör sel Ana log Ska la (VAS) ve omuz fonk si yon la rı nı de ğer len dir mek için Cons tant, UC LA ve Omuz Özür lü lük Skor la ma sı (OÖS) kul la nıl dı. Has ta la ra Cod man, pa sif ek lem ha re ket açık lı ğı ve pa sif ger me eg zer siz le ri, ay rı ca ağ rı la rı ol du ğun da kul lan ma la rı için pa ra se ta mol ve ril di. Bü tün has ta la ra et ki le nen omuz la rı nı özel lik le baş se vi ye sin den yu kar da kul lan ma ma la rı öne ril di. Bul gu lar: Has ta lar te da vi ön ce si, te da vi son ra sı ve üçüncü ayın so nun da ye ni den de ğer len di ril di. Te da vi son ra sı ve üçüncü ayın so nun da ki kon trol ler de VAS, Cons tant, UC LA, OÖS pa ra met re le rin de an lam lı dü zel me sap tan dı. So nuç: Bu te da vi nin SSS ta nı sı ko nan has ta lar da er ken dö nem de olum lu so nuç lar ver di ği ve bu has ta lar da ağ rı ve fonk si yon la rı dü zel te rek ya şam ka li te si ni art tı rı cı bir yön tem ola rak gü ven le uy gu la na bi le ce ği so nu cu na va rıl dı.
Objective: To determine the effectiveness of postoperative local anesthesia in tonsillectomy pati... more Objective: To determine the effectiveness of postoperative local anesthesia in tonsillectomy patients using an intra-individual study design. Methods: Thirty patients aged 5-15 were included in a prospective study. Patients received a local infiltration of 0.5% bupivacaine solution on the right tonsillar bed, and received a local infiltration of normal saline on the left tonsillar bed. Patients were asked to localize pain in terms of most disturbing side of the pharynx, on the 1st, 4th, 8th, 16th, 24th hours. Results: Regarding pain over a 24-h period, there was a significant difference between two sides, after the 8th hour. Conclusion: Postoperative local bupivacaine infiltration in tonsillectomy patients was effective in children.
Nöro Psikiyatri Arşivi, 2014
Introduction: The aim of this study was to investigate the risk factors for distal symmetric sens... more Introduction: The aim of this study was to investigate the risk factors for distal symmetric sensory-motor polyneuropathy (DSP) in patients with type 2 diabetes mellitus (DM). Method: Sixty seven patients with type 2 DM (33 males and 34 females) were included in the study. In addition to a detailed neurological examination, the Michigan Neuropathy Screening Instrument was administered to all patients and their total neuropathy scores were calculated. Nerve conduction examinations were performed for all patients. Results: The mean age of the patients was 52.83±.87 years. The mean glycosylated hemoglobin (HbA1C) value was 8.56±2.07% (normal: 3-6.5%). The total neuropathy score significantly correlated with diabetes duration, hypertension, retinopathy, and HbA1C. Conclusion: This study confirms the previous reports regarding the association of neuropathy with poor glycaemic control and duration of the disease. The association of neuropathy with retinopathy and hypertension is important.
Journal of Experimental and Clinical Medicine, 2009
Spinal ve epidural anestezinin QT dispersiyonuna etkisi QT dispersion effect of spinal and epidur... more Spinal ve epidural anestezinin QT dispersiyonuna etkisi QT dispersion effect of spinal and epidural anesthesia.
Türk Oftalmoloji Dergisi, 2012
Serebral palsi (SP), erken çocukluk çağında görülen kronik bir rahatsızlıktır. Gelişimini tamamla... more Serebral palsi (SP), erken çocukluk çağında görülen kronik bir rahatsızlıktır. Gelişimini tamamlayamamış bir beyinden kaynaklanan, ilk iki yaş içinde görülen, ilerleyici olmayan, postür ve hareket bozukluğuna yol açan bir hastalık olarak tanımlanmıştır. Serebral palsili olgularda yüksek oranlarda oftalmolojik problemlerle karşılaşılmasının nedeni, görme fonksiyonunun beyinde geniş bir alan kaplamasından kaynaklanmaktadır. Normal popülasyonda görme sistemi bozukluğu %4 ile 5 arasında değişirken SP li çocuklarda bu oran neredeyse 10 kat daha sık olarak görülmektedir. Serebral palsi hastalarının kontrol altında olmaması, ileri dönemde muayenelerinin yapılması ve hastaların gözlük kullanımında zorluk çıkarması nedeniyle bu hastalarda ambliyopi normal popülasyona göre daha sık görülmektedir. Serebral palsi hastaları, multidisipliner yaklaşım gerektiren tedavi ve desteğe ihtiyaç duyarlar. Bu nedenle SP'li olguların erken dönemde göz hekimlerine yönlendirilerek, detaylı bir oftalmolojik muayenelerinin yapılması önemlidir. Ayrıca çeşitli derecelerde eşlik edebilecek oftalmolojik, odyolojik, ortopedik, psikolojik problemlerine müdahale edilmesi ve özel eğitimlerinin erken yaşlardan itibaren itinayla planlanması sonucu toplum içindeki yerlerini almaları kolaylaştırılabilir. (Turk J Oph thal mol 2012; 42: 219-26) Anah tar Ke li me ler: Serebral palsi, göz, ambliyopi Sum mary Cerebral palsy (CP) is a chronic disease which is seen in early childhood, i.e. in the first two years of life. It is a non-progressive disorder resulting from a defect or lesion in the immature brain and thus leading to posture and movement disorders. The reason for facing high rates of ophthalmologic problems in CP cases is that visual functions are covered in a large area in the brain. While vision defect in the normal population ranges from 4 to 5%, this rate in children with CP is nearly ten times more. Given that patients with CP are not followed up, the ophthalmologic examination is performed in advanced stages and that there are difficulties in spectacle use, amblyopia is detected more often in those patients than in healthy people. The treatment of CP patients needs multidisciplinary cooperation. So, CP patients must be referred to ophthalmologists for a detailed examination in the early stages. Furthermore, other accompanying disorders (audiologic, orthopedic and psychiatric) should be evaluated and rehabilitation programmes should be carefully applied in early stages to help CP patients achieve healthy lifestyle.
Türk Pediatri Arşivi, 2011
E Eb be ev ve ey yn n b be es sl le em me e t ta ar rz z› › a an nk ke et ti i g ge eç çe er rl l... more E Eb be ev ve ey yn n b be es sl le em me e t ta ar rz z› › a an nk ke et ti i g ge eç çe er rl li ik k v ve e g gü üv ve en ni ir rl li ik k ç ça al l› ›fl flm ma as s› › R Re el li ia ab bi il li it ty y a an nd d v va al li id di it ty y s st tu ud dy y o of f p pa ar re en nt ta al l f fe ee ed di in ng g s st ty yl le e q qu ue es st ti io on nn na ai ir re e M Mu us st ta af fa a Ö Öz zç çe et ti in n, , R Re es su ul l Y Y› ›l lm ma az z, , Ü Ün na al l E Er rk ko or rk km ma az z* *, , H Ha al lu uk k E Es sm me er ra ay y
Tuberkuloz ve Toraks, 2011
To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monox... more To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monoxide (eCO) and hair nicotine (HN) and to evaluate the relationship between these values. Materials and methods: Included in the study were 96 subjects (64 male, 32 female) divided into 3 groups. Th e subjects in Group 1 (n = 46) were current smokers, and the subjects in Group 2 (n = 20) and Group 3 (n = 30) were nonsmokers with or without environmental TS exposure, respectively. Th e eCO level of all of the subjects was measured with a breath CO monitor. Gas chromatography/mass spectrometry were used for quantifi cation of the HN (n = 47). Results: Th e mean age of the subjects was 39.1 years. Th e mean levels of eCO were 9.3 ppm, 1.3 ppm, and 1.0 ppm and the mean HN concentrations were 20.9 ng/mg, 2.1 ng/mg, and 0.7 ng/mg in the 3 groups, respectively. Th ere was a signifi cant diff erence between Group 1 and the other groups according to the levels of eCO and HN concentrations, but the levels of eCO and HN concentrations were similar in Group 2 and Group 3. Th ere was a positive correlation between the levels of eCO and the HN concentrations. Th e cutoff values of eCO and HN for smokers were 6 ppm and 4 ng/mg, respectively. Conclusion: Although nicotine analysis in some biological samples like hair is specifi c to TS exposure, these methods are expensive and diffi cult procedures. Our results suggest that instead of HN analysis, a cheap and easy method like eCO measurement may be used, but further studies with more cases are needed.
Turkish Journal of Trauma and Emergency Surgery, 2013
Apandisit çocuklardaki en sık cerrahi karın ağrısı nedenidir. Biz bu çalışmada apandektomilerin h... more Apandisit çocuklardaki en sık cerrahi karın ağrısı nedenidir. Biz bu çalışmada apandektomilerin histopatolojileri üzerine yaş, cinsiyet, mevsim ve ailesel faktörlerin etkisini araştırdık. GEREÇ VE YÖNTEM: Akut apandisit nedeni ile Eylül 2009-2011 yılları arasında ameliyat edilen 588 hasta çalışmaya alındı. Hastalar histopatolojik bulgularına göre akut, perfore ve negatif apandektomi olarak üç gruba ayrıldı. Bu gruplar üzerine yaş, cinsiyet, mevsim ve ailesel faktörlerin etkinliği araştırıldı. BULGULAR: Hastaların ortalama yaşı 11.8±3.26 yıl (dağılım, 1-16 yıl) idi. Hastaların analizinde 10 yaşından sonra apandisit 2.41 kez sık görüldü. Erkeklerde apandisit kızlara göre 4.63 kez daha sık bulundu. Negatif apendektomi ile 10 yaşından sonra daha sık karşılaşıldı. Aile hikayesi ve mevsimlerin apandisit üzerine etkisi oransal olarak saptandı fakat bu etki anlamlı değildi (p>0.05). SONUÇ: Apandisit cerrahisi planlarken yaş ve cinsiyet dikkate alınmalıdır. Çünkü doğru tanı yaş ve cinsiyet ile ilişkilidir. Ayrıca apandisit histopatolojisi ailesel ve çevresel faktörlerden etkilenir.
Turkish Journal of Medical Sciences
To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monox... more To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monoxide (eCO) and hair nicotine (HN) and to evaluate the relationship between these values. Materials and methods: Included in the study were 96 subjects (64 male, 32 female) divided into 3 groups. Th e subjects in Group 1 (n = 46) were current smokers, and the subjects in Group 2 (n = 20) and Group 3 (n = 30) were nonsmokers with or without environmental TS exposure, respectively. Th e eCO level of all of the subjects was measured with a breath CO monitor. Gas chromatography/mass spectrometry were used for quantifi cation of the HN (n = 47). Results: Th e mean age of the subjects was 39.1 years. Th e mean levels of eCO were 9.3 ppm, 1.3 ppm, and 1.0 ppm and the mean HN concentrations were 20.9 ng/mg, 2.1 ng/mg, and 0.7 ng/mg in the 3 groups, respectively. Th ere was a signifi cant diff erence between Group 1 and the other groups according to the levels of eCO and HN concentrations, but the levels of eCO and HN concentrations were similar in Group 2 and Group 3. Th ere was a positive correlation between the levels of eCO and the HN concentrations. Th e cutoff values of eCO and HN for smokers were 6 ppm and 4 ng/mg, respectively. Conclusion: Although nicotine analysis in some biological samples like hair is specifi c to TS exposure, these methods are expensive and diffi cult procedures. Our results suggest that instead of HN analysis, a cheap and easy method like eCO measurement may be used, but further studies with more cases are needed.
Turkish Journal of Medical Sciences
To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine ... more To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic conjunctivitis was provoked by a mast cell activator (compound 48/80) in 31 New Zealand rabbits. The rabbits were divided into 3 groups, and 1% CAPE, 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate were instilled 30 min before and 15 min after the provocation. The edema and hyperemia in the experimental (right) eyes and control (left) eyes were scored in each group. Anterior segment photographs and conjunctival samples for histopathological evaluation and scoring were taken. Results: When the edema and hyperemia scores of the postprovocation term were compared with those of the provocation term, a significant difference was detected in each group (P = 0.021, P = 0.037, P = 0.0001). The histopathological scores of the provocation and postprovocation terms were evaluated; a statistically significant difference was found in the CAPE and dexamethasone sodium phosphate groups (P = 0.003, P = 0.014), but not in the olopatadine group (P = 0.096). Conclusion: This study demonstrated that 1% CAPE was as clinically efficacious as 0.1% olopatadine and 0.1% dexamethasone. Thus, 1% CAPE may be an alternative to 0.1% olopatadine and 0.1% dexamethasone in the management of acute allergic reactions.
BackgroundAcute appendicitis is the most common non-gynecological emergency during pregnancy. The... more BackgroundAcute appendicitis is the most common non-gynecological emergency during pregnancy. The diagnosis of appendicitis during pregnancy is challenging due to both physiological and laboratory changes. As such, the surgeon needs additional guidance, other than imaging methods, before deciding a surgical intervention. Various scoring methods have been defined and evaluated for the diagnosis of acute appendicitis for a long time. There is no definition of a score for the gestation period, and the comparison of the currently applied scoring methods during the gestation period is not available in the literature.The purpose of our study is to evaluate the efficacy of the most popular scoring systems applied in the diagnosis of acute appendicitis in pregnancy and the tips for introduction to a scoring method for the pregnancy period.MethodsThis single-center retrospective study consists of 79 pregnant patients who were admitted to the emergency department with abdominal pain between M...
JPMA. The Journal of the Pakistan Medical Association, 2017
To assess whether the Iowa Infant Feeding Attitude Scale is a valid and reliable scale for Turkis... more To assess whether the Iowa Infant Feeding Attitude Scale is a valid and reliable scale for Turkish mothers, and to assess maternal attitudes toward various aspects of infant feeding. This methodological, analytical study was conducted at the obstetrics and gynaecology department of Sakarya Training and Research Hospital, Sakarya, Turkey, from June to August 2015, and comprised mothers of newborn babies. Data was collected using the Turkish version of Iowa Infant Feeding Attitude Scale. SPSS 23 was used for data analysis. There were 391 participants in the study. Five items of the original Iowa Infant Feeding Attitude Scale were excluded due to the low correlation with the scale integrity (Cronbach's alpha=0.67). The total mean score of the mothers was 48.11±6.57. A statistically significant difference was found between the educational status, having social security, what the mothers having other children fed these children in the first 6 months and family types (p=0.05 each). Si...
Cumhuriyet Medical Journal, 2017
The aim of the study was to compare nasal mucosal vasodilation induced by two different anestheti... more The aim of the study was to compare nasal mucosal vasodilation induced by two different anesthetic used to provide controlled hypotension with the aid of acoustic rhinometry (AR). Method: This study is prospective randomized clinical study. Fifty patients were randomized into propofol (Group P; n=25) and sevoflurane (Group S; n=25) groups. During anesthesia induction, Group P received propofol (2 mg kg-1 IV) and Group S was administered sevoflurane at a minimal alveolar concentration of 6-8%. Anesthesia was maintained with propofol (4 mg kg h-1) in Group P and 2% sevoflurane in Group S. Both groups received the analgesic remifentanil at a dose of 0.025 µg kg min-1. Patients were performed nasal acoustic rhinometry (AR) measurements. Anesthetic doses were adjusted so as to ensure intraoperative hypotension by maintaining mean arterial pressure at 20-25% lower than the baseline value. Results: In both groups, a significant difference was detected between AR and nasal minimal cross-sectional areas (MCA) measurements taken from the patients in the supine position, both during the preoperative period and at 30 minutes after the induction of anesthesia, but a meaningful decrease in MCA1 and MCA2 values after the induction of anesthesia was observed for both groups. In addition, differences in measurements taken before and after the induction of anesthesia were greater in amplitude for the sevoflurane group versus the propofol group. Conclusions: Controlled hypotension induced using sevoflurane anesthesia might result in higher degrees of vasodilation relative to propofol anesthesia.
South African Medical Journal, 2012
Cumhuriyet Medical Journal, 2014
Aim. Q fever, which is a zoonosis caused by Coxiella burnetii, may result in abortions in infecte... more Aim. Q fever, which is a zoonosis caused by Coxiella burnetii, may result in abortions in infected animals and pregnant women. In our study, we searched the association between Q fever serology and abortion in a region where Q fever is endemic. Method. This study was conducted in Gaziosmanpaşa University Hospital between March and May 2012. A total of 100 women, from these, 64 had a history of spontaneus abortion (cases) and 36 had live births with no complicated obstetrics history or complicated partum (controls), enrolled in the study. Both groups were compared according to where they live, underlying diseases, contact with farm animals or pets and village connectivity. Results. IgG seroprevalence of Coxiella in our study group with the history of abortion was 15.6%, and 11.1% in the control group (p>0.05). When case and control groups were compared, the frequency of inhabitants of the village (p=0.012), subjects who had contact with farm animals [p=0.026, especially cattle (p=0.013)] or domestic animals (p=0.018) in case group were more common than the control group. When all the samples were analyzed, it was seen that the only significant variable affecting Coxiella IgG seropositivity was residency in rural area or visiting rural area (p=0.018). Conclusions. We have found that the relation between abortion and Q fever infection was not statistically significant. On this issue, multicenter studies which have the higher number of samples are needed in our country.
Sakarya Medical Journal, 2015
Objective: Aim of this study is to analyze the change of the area under the adjusted ROC (AdjROC)... more Objective: Aim of this study is to analyze the change of the area under the adjusted ROC (AdjROC) curve in certain conditions via binormal distribution model using simulation studies and application of this algorithm to real data. Materials and Methods: Data sets simulated according to various conditions. PSA and age values of 125 patients who were examined prostate biopsy with pre-diagnosis of prostate cancer in Gaziosmanpasa University Faculty of Medicine Department of Urology at the years of 2005 to 2007. An algorithm and code program was written that make simulation according to various condition using PROC IML procedure in SAS statistical software.Results: According to the simulation study, if biomarker indicators in healthy group are constant and are lower or equal in healthy group than/to disease group, both adjusted AUC (AdjAUC) and AUC have small values and, no significant difference was found between them. The AUC was significantly larger when the biomarker indicators in disease group were higher. In addition, if the correlation between the covariate and biomarker is high in disease group and if AUC is approximately 0.75, then there is significant difference between adjusted AUC and AUC. PSA (Prostate Specific Antigen), a biomarker used for prostate cancer diagnosis, was analyzed based on the adjustments by age. It was found that adjusted AUC value was higher than unadjusted AUC value. Conclusions: For the adjusted ROC model being applicable, covariate and biomarker distributions must show double binormal distribution. If the biomarker can distinguish disease and healthy individuals correctly, then covariate is not needed. If correlation of healthy is approaching to 0 and correlation of disease is 0.50, and if AUC is less than 0.75, then covariate must be included in the model. Model does not work well when sample size of disease and healthy are less than 50.
Nutrición hospitalaria
Eating style is one of the prominente factors that determine energy intake. One of the influencin... more Eating style is one of the prominente factors that determine energy intake. One of the influencing factors that determine parental feeding style is parental perception of the weight status of the child. The aim of this study is to evaluate the relationship between maternal visual perception of their children's weight status and their feeding style. A cross-sectional survey was completed with only mother's of 380 preschool children with age of 5 to 7 (6.14 years). Visual perception scores were measured with a sketch and maternal feeding style was measured with validated "Parental Feeding Style Questionnaire". The parental feeding dimensions "emotional feeding" and "encouragement to eat" subscale scores were low in overweight children according to visual perception classification. "Emotional feeding" and "permissive control" subscale scores were statistically different in children classified as correctly perceived and incorrect...
Iranian journal of arthropod-borne diseases, 2009
The World health Organization (WHO) declares Crimean Congo hemorrhagic fever (CCHF) endemic in Tu... more The World health Organization (WHO) declares Crimean Congo hemorrhagic fever (CCHF) endemic in Turkey. Despite the magnitude of problem, no documented evidence exists in Turkey, which reveals the awareness and practices of the country's adult population regarding CCHF, its spread, symptoms, treatment, and prevention. This study was conducted to assess the level of knowledge, attitudes, and practices regarding CCHF in people visiting tertiary care hospital in Tokat, Turkey. This questionnaire based cross-sectional survey was conducted among patients' relatives or guardians who admitted pediatric outpatient clinics during May-July 2008. The questionnaire was composed of 25 questions. A total of 1034 respondents participated in the survey. Sufficient knowledge about CCHF was not found in 28.9% of the sample. Literate individuals were relatively better informed about CCHF as compared to the illiterate people. Television and radio were considered as the most important and useful ...
Mikrobiyoloji bülteni, 2008
Transmission routes and seroprevalence of hepatitis C virus (HCV) may vary between countries and ... more Transmission routes and seroprevalence of hepatitis C virus (HCV) may vary between countries and geographic regions. In this study, we aimed to investigate the risk factors associated with the transmission of HCV in our region, Tokat (located at middle Black Sea region of Turkey). Ninety-seven patients (age range: 16- 78-years-old, mean age: 53.6 +/- 10 yrs; 15 male, 82 female) who were admitted to Infectious Diseases Clinics between September 2004 and February 2007 and found to be anti-HCV positive by microparticle enzyme immunoassay (Abbott, Axsym) were enrolled in this study. The patients were evaluated for the risk factors including blood transfusion, past surgery, medical abortion, dental therapy, history of endoscopy/bronchoscopy, intravenous (i.v.) drug use, hospitalization exceeding one week and hemodialysis. "Sexual contact with multiple partners" has not been evaluated as a risk factor since the sociocultural features of this specific region would possibly preven...
ÖZET Amaç: Bu ça lış ma mı zın ama cı, su bak ro mi yal sı kış ma sen dro mu (SSS) ta nı sı ko na... more ÖZET Amaç: Bu ça lış ma mı zın ama cı, su bak ro mi yal sı kış ma sen dro mu (SSS) ta nı sı ko nan has ta lar da pe lo id uy gu la ma la rı nı içe ren bal ne o te ra pi nin ağ rı ve fonk si yo nel du rum üze rin de ki et ki le ri ni de ğer len dir mek tir. Gereç ve Yöntemler: Kli nik ve rad yo lo jik ola rak su bak ro mi al sı kış ma sen dro mu ta nı sı alan ve ya kın ma sü re si en az üç ay olan 29 has ta ça lış ma ya alın dı. Has ta la rı mı zın or ta la ma ya şı 48.24 ± 6.83 (33-60) yıl olup, 23’ü ka dın ve altısı er kek idi. Uy gu la dı ğı mız pe lo id, 45°C sı cak lı ğın da ve 30 da ki ka sü re ile gün de bir se ans lo kal pe lo id pa ket tar zın da uy gu lan dı. Te da vi ye haf ta içi beş gün ola rak 15 se ans de vam edil di. Ağ rı nın şid de ti ni de ğer len dir mek için Gör sel Ana log Ska la (VAS) ve omuz fonk si yon la rı nı de ğer len dir mek için Cons tant, UC LA ve Omuz Özür lü lük Skor la ma sı (OÖS) kul la nıl dı. Has ta la ra Cod man, pa sif ek lem ha re ket açık lı ğı ve pa sif ger me eg zer siz le ri, ay rı ca ağ rı la rı ol du ğun da kul lan ma la rı için pa ra se ta mol ve ril di. Bü tün has ta la ra et ki le nen omuz la rı nı özel lik le baş se vi ye sin den yu kar da kul lan ma ma la rı öne ril di. Bul gu lar: Has ta lar te da vi ön ce si, te da vi son ra sı ve üçüncü ayın so nun da ye ni den de ğer len di ril di. Te da vi son ra sı ve üçüncü ayın so nun da ki kon trol ler de VAS, Cons tant, UC LA, OÖS pa ra met re le rin de an lam lı dü zel me sap tan dı. So nuç: Bu te da vi nin SSS ta nı sı ko nan has ta lar da er ken dö nem de olum lu so nuç lar ver di ği ve bu has ta lar da ağ rı ve fonk si yon la rı dü zel te rek ya şam ka li te si ni art tı rı cı bir yön tem ola rak gü ven le uy gu la na bi le ce ği so nu cu na va rıl dı.
Objective: To determine the effectiveness of postoperative local anesthesia in tonsillectomy pati... more Objective: To determine the effectiveness of postoperative local anesthesia in tonsillectomy patients using an intra-individual study design. Methods: Thirty patients aged 5-15 were included in a prospective study. Patients received a local infiltration of 0.5% bupivacaine solution on the right tonsillar bed, and received a local infiltration of normal saline on the left tonsillar bed. Patients were asked to localize pain in terms of most disturbing side of the pharynx, on the 1st, 4th, 8th, 16th, 24th hours. Results: Regarding pain over a 24-h period, there was a significant difference between two sides, after the 8th hour. Conclusion: Postoperative local bupivacaine infiltration in tonsillectomy patients was effective in children.
Nöro Psikiyatri Arşivi, 2014
Introduction: The aim of this study was to investigate the risk factors for distal symmetric sens... more Introduction: The aim of this study was to investigate the risk factors for distal symmetric sensory-motor polyneuropathy (DSP) in patients with type 2 diabetes mellitus (DM). Method: Sixty seven patients with type 2 DM (33 males and 34 females) were included in the study. In addition to a detailed neurological examination, the Michigan Neuropathy Screening Instrument was administered to all patients and their total neuropathy scores were calculated. Nerve conduction examinations were performed for all patients. Results: The mean age of the patients was 52.83±.87 years. The mean glycosylated hemoglobin (HbA1C) value was 8.56±2.07% (normal: 3-6.5%). The total neuropathy score significantly correlated with diabetes duration, hypertension, retinopathy, and HbA1C. Conclusion: This study confirms the previous reports regarding the association of neuropathy with poor glycaemic control and duration of the disease. The association of neuropathy with retinopathy and hypertension is important.
Journal of Experimental and Clinical Medicine, 2009
Spinal ve epidural anestezinin QT dispersiyonuna etkisi QT dispersion effect of spinal and epidur... more Spinal ve epidural anestezinin QT dispersiyonuna etkisi QT dispersion effect of spinal and epidural anesthesia.
Türk Oftalmoloji Dergisi, 2012
Serebral palsi (SP), erken çocukluk çağında görülen kronik bir rahatsızlıktır. Gelişimini tamamla... more Serebral palsi (SP), erken çocukluk çağında görülen kronik bir rahatsızlıktır. Gelişimini tamamlayamamış bir beyinden kaynaklanan, ilk iki yaş içinde görülen, ilerleyici olmayan, postür ve hareket bozukluğuna yol açan bir hastalık olarak tanımlanmıştır. Serebral palsili olgularda yüksek oranlarda oftalmolojik problemlerle karşılaşılmasının nedeni, görme fonksiyonunun beyinde geniş bir alan kaplamasından kaynaklanmaktadır. Normal popülasyonda görme sistemi bozukluğu %4 ile 5 arasında değişirken SP li çocuklarda bu oran neredeyse 10 kat daha sık olarak görülmektedir. Serebral palsi hastalarının kontrol altında olmaması, ileri dönemde muayenelerinin yapılması ve hastaların gözlük kullanımında zorluk çıkarması nedeniyle bu hastalarda ambliyopi normal popülasyona göre daha sık görülmektedir. Serebral palsi hastaları, multidisipliner yaklaşım gerektiren tedavi ve desteğe ihtiyaç duyarlar. Bu nedenle SP'li olguların erken dönemde göz hekimlerine yönlendirilerek, detaylı bir oftalmolojik muayenelerinin yapılması önemlidir. Ayrıca çeşitli derecelerde eşlik edebilecek oftalmolojik, odyolojik, ortopedik, psikolojik problemlerine müdahale edilmesi ve özel eğitimlerinin erken yaşlardan itibaren itinayla planlanması sonucu toplum içindeki yerlerini almaları kolaylaştırılabilir. (Turk J Oph thal mol 2012; 42: 219-26) Anah tar Ke li me ler: Serebral palsi, göz, ambliyopi Sum mary Cerebral palsy (CP) is a chronic disease which is seen in early childhood, i.e. in the first two years of life. It is a non-progressive disorder resulting from a defect or lesion in the immature brain and thus leading to posture and movement disorders. The reason for facing high rates of ophthalmologic problems in CP cases is that visual functions are covered in a large area in the brain. While vision defect in the normal population ranges from 4 to 5%, this rate in children with CP is nearly ten times more. Given that patients with CP are not followed up, the ophthalmologic examination is performed in advanced stages and that there are difficulties in spectacle use, amblyopia is detected more often in those patients than in healthy people. The treatment of CP patients needs multidisciplinary cooperation. So, CP patients must be referred to ophthalmologists for a detailed examination in the early stages. Furthermore, other accompanying disorders (audiologic, orthopedic and psychiatric) should be evaluated and rehabilitation programmes should be carefully applied in early stages to help CP patients achieve healthy lifestyle.
Türk Pediatri Arşivi, 2011
E Eb be ev ve ey yn n b be es sl le em me e t ta ar rz z› › a an nk ke et ti i g ge eç çe er rl l... more E Eb be ev ve ey yn n b be es sl le em me e t ta ar rz z› › a an nk ke et ti i g ge eç çe er rl li ik k v ve e g gü üv ve en ni ir rl li ik k ç ça al l› ›fl flm ma as s› › R Re el li ia ab bi il li it ty y a an nd d v va al li id di it ty y s st tu ud dy y o of f p pa ar re en nt ta al l f fe ee ed di in ng g s st ty yl le e q qu ue es st ti io on nn na ai ir re e M Mu us st ta af fa a Ö Öz zç çe et ti in n, , R Re es su ul l Y Y› ›l lm ma az z, , Ü Ün na al l E Er rk ko or rk km ma az z* *, , H Ha al lu uk k E Es sm me er ra ay y
Tuberkuloz ve Toraks, 2011
To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monox... more To investigate the eff ect of tobacco smoke (TS) exposure on the quantity of exhaled carbon monoxide (eCO) and hair nicotine (HN) and to evaluate the relationship between these values. Materials and methods: Included in the study were 96 subjects (64 male, 32 female) divided into 3 groups. Th e subjects in Group 1 (n = 46) were current smokers, and the subjects in Group 2 (n = 20) and Group 3 (n = 30) were nonsmokers with or without environmental TS exposure, respectively. Th e eCO level of all of the subjects was measured with a breath CO monitor. Gas chromatography/mass spectrometry were used for quantifi cation of the HN (n = 47). Results: Th e mean age of the subjects was 39.1 years. Th e mean levels of eCO were 9.3 ppm, 1.3 ppm, and 1.0 ppm and the mean HN concentrations were 20.9 ng/mg, 2.1 ng/mg, and 0.7 ng/mg in the 3 groups, respectively. Th ere was a signifi cant diff erence between Group 1 and the other groups according to the levels of eCO and HN concentrations, but the levels of eCO and HN concentrations were similar in Group 2 and Group 3. Th ere was a positive correlation between the levels of eCO and the HN concentrations. Th e cutoff values of eCO and HN for smokers were 6 ppm and 4 ng/mg, respectively. Conclusion: Although nicotine analysis in some biological samples like hair is specifi c to TS exposure, these methods are expensive and diffi cult procedures. Our results suggest that instead of HN analysis, a cheap and easy method like eCO measurement may be used, but further studies with more cases are needed.
Turkish Journal of Trauma and Emergency Surgery, 2013
Apandisit çocuklardaki en sık cerrahi karın ağrısı nedenidir. Biz bu çalışmada apandektomilerin h... more Apandisit çocuklardaki en sık cerrahi karın ağrısı nedenidir. Biz bu çalışmada apandektomilerin histopatolojileri üzerine yaş, cinsiyet, mevsim ve ailesel faktörlerin etkisini araştırdık. GEREÇ VE YÖNTEM: Akut apandisit nedeni ile Eylül 2009-2011 yılları arasında ameliyat edilen 588 hasta çalışmaya alındı. Hastalar histopatolojik bulgularına göre akut, perfore ve negatif apandektomi olarak üç gruba ayrıldı. Bu gruplar üzerine yaş, cinsiyet, mevsim ve ailesel faktörlerin etkinliği araştırıldı. BULGULAR: Hastaların ortalama yaşı 11.8±3.26 yıl (dağılım, 1-16 yıl) idi. Hastaların analizinde 10 yaşından sonra apandisit 2.41 kez sık görüldü. Erkeklerde apandisit kızlara göre 4.63 kez daha sık bulundu. Negatif apendektomi ile 10 yaşından sonra daha sık karşılaşıldı. Aile hikayesi ve mevsimlerin apandisit üzerine etkisi oransal olarak saptandı fakat bu etki anlamlı değildi (p>0.05). SONUÇ: Apandisit cerrahisi planlarken yaş ve cinsiyet dikkate alınmalıdır. Çünkü doğru tanı yaş ve cinsiyet ile ilişkilidir. Ayrıca apandisit histopatolojisi ailesel ve çevresel faktörlerden etkilenir.