Anish Upreti - Academia.edu (original) (raw)

Papers by Anish Upreti

567 The differential diagnosis of lateral ventricular tumors was explored by retrospective analys... more 567 The differential diagnosis of lateral ventricular tumors was explored by retrospective analysis of 47 pathologically proved cases identified by CT and{or MR imaging. Third ventricular tumors adjacent to the foramen of Monro (e.g., colloid cysts) were excluded. Forty-six patients underwent CT, and eight had MR imaging. The most common neo-plasms were choroid plexus papilloma (10 cases) and meningioma (nine cases). Other common neoplasms included subependymoma (six cases), subependymal giant cell astrocytoma (five cases), and metastasis/lymphoma (four cases). Important features for differential diagnosis included age of the patient, the tumor's location within the lateral ventricle, and density on CT before IV administration of contrast material. Fifty percent of the tumors were in the ventricular atrium. All intraventricular tumor types (except subependymoma) showed contrast enhancement. MR was most useful in evaluating tumor location, size, and extent, but it did not help in eliminating alternative diagnoses. On the basis of patients' ages, specific tumor location, and the appearance on CT scans or MR images, an algorithm for differential diagnosis of lateral ventricular tumors was developed. Lateral ventricular neoplasms are easily detected with CT and MR. Previous studies of the radiologic appearance of intraventricular tumors have been based on histologic type alone (1-3]. This study of 47 lateral ventricular neoplasms by CT andjor MR correlates imaging characteristics of these lesions with patients' ages and the specific location of the tumor within the lateral ventricle. We think that this approach improves the accuracy of the preoperative diagnosis. Materials and Methods Forty-seven cases of lateral ventricular neoplasms with cross-sectional imaging studies were found in the 1978-1988 neuroradiology archives. The radiologic, histologic, and clinical data of these cases were reviewed retrospectively. Tissue was derived by needle biopsy (three cases), open biopsy (40 cases), or autupsy (four cases). All pathologic cases were reviewed at the Armed Forces Institute of Pathology (AFiP), and all these diagnoses we re confirmed. Tumors were considered to be within the lateral ventricle only if radiologic studies showed that the lesion was predominantly intraventricular with little extraventricular extent or that the lesion arose from within the lateral ventricle. Primary or metastatic neoplasms that appeared largely parenchymal and had some lateral ventricular extension were not included in this study. CT scans, both unenhanced (39 of 46 cases) and enhanced (42 of 46 cases) , were examined to determine the location and size of each tumor. Additionally , the neoplasm 's morphologic characteristics were evaluated, including unenhanced CT appearance , degree of enhancement, and the presence of calcification or cystic change. MR studies were available in 1 0 patients. These studies were evaluated for the signal characteristics on T1-weighted , T2-weighted , and either proton-density-weighted or inter

567 The differential diagnosis of lateral ventricular tumors was explored by retrospective analys... more 567 The differential diagnosis of lateral ventricular tumors was explored by retrospective analysis of 47 pathologically proved cases identified by CT and{or MR imaging. Third ventricular tumors adjacent to the foramen of Monro (e.g., colloid cysts) were excluded. Forty-six patients underwent CT, and eight had MR imaging. The most common neo-plasms were choroid plexus papilloma (10 cases) and meningioma (nine cases). Other common neoplasms included subependymoma (six cases), subependymal giant cell astrocytoma (five cases), and metastasis/lymphoma (four cases). Important features for differential diagnosis included age of the patient, the tumor's location within the lateral ventricle, and density on CT before IV administration of contrast material. Fifty percent of the tumors were in the ventricular atrium. All intraventricular tumor types (except subependymoma) showed contrast enhancement. MR was most useful in evaluating tumor location, size, and extent, but it did not help in eliminating alternative diagnoses. On the basis of patients' ages, specific tumor location, and the appearance on CT scans or MR images, an algorithm for differential diagnosis of lateral ventricular tumors was developed. Lateral ventricular neoplasms are easily detected with CT and MR. Previous studies of the radiologic appearance of intraventricular tumors have been based on histologic type alone (1-3]. This study of 47 lateral ventricular neoplasms by CT andjor MR correlates imaging characteristics of these lesions with patients' ages and the specific location of the tumor within the lateral ventricle. We think that this approach improves the accuracy of the preoperative diagnosis. Materials and Methods Forty-seven cases of lateral ventricular neoplasms with cross-sectional imaging studies were found in the 1978-1988 neuroradiology archives. The radiologic, histologic, and clinical data of these cases were reviewed retrospectively. Tissue was derived by needle biopsy (three cases), open biopsy (40 cases), or autupsy (four cases). All pathologic cases were reviewed at the Armed Forces Institute of Pathology (AFiP), and all these diagnoses we re confirmed. Tumors were considered to be within the lateral ventricle only if radiologic studies showed that the lesion was predominantly intraventricular with little extraventricular extent or that the lesion arose from within the lateral ventricle. Primary or metastatic neoplasms that appeared largely parenchymal and had some lateral ventricular extension were not included in this study. CT scans, both unenhanced (39 of 46 cases) and enhanced (42 of 46 cases) , were examined to determine the location and size of each tumor. Additionally , the neoplasm 's morphologic characteristics were evaluated, including unenhanced CT appearance , degree of enhancement, and the presence of calcification or cystic change. MR studies were available in 1 0 patients. These studies were evaluated for the signal characteristics on T1-weighted , T2-weighted , and either proton-density-weighted or inter