Usama Tariq - Academia.edu (original) (raw)

Papers by Usama Tariq

2018 IEEE International Conference on Robotics and Automation (ICRA)

Cancer occurs as a result of deregulation of body’s integral pathways involved in growth, prolife... more Cancer occurs as a result of deregulation of body’s integral pathways involved in growth, proliferation, differentiation, and defense. The disease kills millions of people worldwide every year and is multifaceted in nature. Several efforts have been made to find a cure against cancer; however, owing to its nature, a single treatment has not been developed yet. Consequently, scientists are investing in developing multiple cures against different types of cancers to decrease the death toll. Such efforts widened the pool of available therapeutic options such as chemotherapy, surgery, radiation therapy, targeted therapy, nucleic acid-based therapy, etc. In this chapter, the diverse forms of treatment options from conventional to the most updated ones are described in detail with their advantages and limitations. Moreover, the chapter also talks about CRISPR-based cancer therapeutics and its application in the clinic.

Neurology, 2018

Objective: We seek to characterize the clinical symptoms and describe the treatment paradigm of a... more Objective: We seek to characterize the clinical symptoms and describe the treatment paradigm of a rare case of autoimmune encephalitis secondary to neuronal ganglionic acetylcholine receptor autoimmunity. Background: Autoimmune encephalopathy can be used to describe a range of neuropsychiatric disorders in which autoantibodies are directed against central nervous system targets. While nicotinic ganglionic acetylcholine receptor autoimmunity has been commonly reported in dysautonomia and peripheral neuropathy, this type of autoimmunity has rarely been shown to cause encephalopathy. Currently, there is limited data regarding the cognitive and behavioral changes which occur in this syndrome, and the efficacy of immunomodulatory therapy. Design/Methods: A case report. Results: A 54 year-old previously healthy, right-handed male presented to clinic for evaluation of one year of cognitive impairment which was simultaneous with the onset of severe eczema. He reported weekly cognitive fluct...

Hyperglycemia is a metabolic issue rising mortality and bleakness around the world. The point of ... more Hyperglycemia is a metabolic issue rising mortality and bleakness around the world. The point of efficacy study was to explore the impact of flaxseeds and chia seeds on type 2 diabetes mellitus in light of the fact that they are financially savvy and gives a great deal of medicinal advantages and are attainable to low and middle salary populace. Both comprise of many vital substances like omega-3 and omega-6, dissolvable dietary fiber, and phytochemicals. To produce the desired results of flaxseeds and chia seeds fortified yogurt to reduce hyperglycemia an efficacy study design was carried out. Fifteen healthy rodents weighing 150280g, 2-3 months old were utilized for the examination. Rats which tested were nourished high sucrose diet for diabetes induction for roughly 15 days. Following 15 days, with the assistance of glucometer blood glucose level was checked to ratify hyperglycemia. Fifteen healthy rodents were distributed into three groups having five rodents in each. The group ...

Objective: To describe a novel case of mixed transcortical aphasia in association with neurodegen... more Objective: To describe a novel case of mixed transcortical aphasia in association with neurodegenerative disease. Background: Mixed transcortical aphasia is a rare speech disorder characterized by reduced spontaneous speech and decreased comprehension with intact repetition. This type of aphasia has been seen previously in patients with brain infarction, particularly with ischemia of watershed areas which isolate Broca’s area, Wernicke’s areas, and the arcuate fasciculus from rest of the brain. Design/Methods: A case report. Results: we report a 55 year old right-handed female who gradually developed language difficulties over two years. Symptoms began with difficulty finding words and word production. On neuropsychologic testing, she was found to have impaired spontaneous speech, impaired comprehension and naming, with intact repetition. Her MRI showed atrophy in the left frontal, parietal and anterior temporal lobe, without evidence of ischemia. Conclusions: Primary progressive ap...

In near future, robots are envisioned to work alongside humans in professional anddomestic enviro... more In near future, robots are envisioned to work alongside humans in professional anddomestic environments without significant restructuring of workspace. Roboticsystems in such setups must be adept a ...

Many hazard identification and risk management techniques are used in chemical process industries... more Many hazard identification and risk management techniques are used in chemical process industries (like HAZOP, QRA, PHA) at the design stage and in operational plants to ensure smooth and safe run of all l plant operations and activities.. The implementation of these techniques is robust, yet accidents happen in chemical process industry. The investigation of such accidents has shown that the active measures for prevention are inadequate and are often poorly designed. The purpose of this manuscript is to study a gas processing facility and identify the needs for such active measures which will act as first line of intervention to fire incidents, that will help in avoiding the escalation of small incident towards a catastrophic event.

2021 International Bhurban Conference on Applied Sciences and Technologies (IBCAST)

This study aims at describing a methodology for the Static Structural Analysis of Fighter Aircraf... more This study aims at describing a methodology for the Static Structural Analysis of Fighter Aircraft's wing spars for identification of critical stresses. Aircraft's wing is subjected to various flight loads i.e. bending loads, twisting loads, shear stress etc. This analysis helps to determine structural and material safety limit of aircraft's wing. Also, the location of critical stresses, that arises due to different loading actions on both wing and wing spars, can be determine. The failure of aircraft wing while performing different maneuvers like pulling g's can cause catastrophic results. Therefore, for safety concerns, different analysis was done on aircraft's wing. So, in this paper, bending stress, shear stress and von mises stress was calculated analytically and numerically for different loading conditions and then critical stresses were formulated and identified for failure or yielding points of wing spars. For ANSYS Simulation, CAD Models of wing and wing spars were imported in ANSYS workbench and static structural analysis was done to obtain critical stresses. Von Mises yield theory was used to formulate and identify critical stresses and yielding stresses. Numerical stress simulation was done in ANSYS and results for Von Mises Stress were obtained for different loading conditions. The results obtained from using both analytical calculation and numerical simulation were analyzed. Some of the ANSYS simulated results were exceeding beyond yield limit at some loading conditions and these exceeding results for both wing and spars were marked as critical stresses. The locations of these critical stresses were at attachment or fixed point of wing spars.

Archives of Clinical Neuropsychology

Background/Objectives Whereas rare cases of hemispatial visual neglect have been reported in pati... more Background/Objectives Whereas rare cases of hemispatial visual neglect have been reported in patients with a neurodegenerative disease, quadrantic visuospatial neglect has not been described. We report a patient with probable posterior cortical atrophy who demonstrated lower right-sided quadrantic visuospatial neglect, together with allocentric vertical neglect. Methods/Results A 68-year-old man initially noted deficits in reading and writing. Subsequently, he developed other cognitive deficits. On vertical line bisections, he deviated upward, and on horizontal line bisections, he deviated to the left. These deviations together suggest that this man’s neglect might be most severe in his right (head/body-centered) lower (below eye level) visual space. When attempting to perform vertical line bisections in all four egocentric quadrants, his upward deviations were largest in the right lower quadrant. On a cancelation test, he revealed bilateral lower (ventral) allocentric neglect but n...

European Heart Journal, 2013

Myocardial and pericardial diseases 695 sis (Sarc). However, few data exist for the predictive ro... more Myocardial and pericardial diseases 695 sis (Sarc). However, few data exist for the predictive role of BNP in mortality in this disease. Our aim was to investigate the predictive role of BNP on all-cause mortality and the possible correlations with other clinical and demographic parameters. Methods: One hundred seventy four consecutive patients (mean age, 48.95±12. 66 years; male/female, 66/108) with biopsy proven sarcoidosis were prospectively studied. Baseline evaluation upon BNP, included conventional echocardiography, 24h ambulatory Holter monitoring with ability to calculate heart rate variability indices and cardiac MRI in case this was indicated. Pulmonary function tests including total lung capacity (TLC) and diffusing capacity for carbon monoxide (DLCO) at baseline were also performed. Results: Average BNP level of all patients was 24.58±28.2 pg/dl. Baseline BNP was significantly correlated with age (p=0.0001, r=0.341),left atrium (p=0.0001, r=0.309), interventricular septum (p=0.0001, r=0.280), posterior wall (p=0.001, r=0.240), transmitral A wave (p=0.003, r=0.228), systolic pressure of pulmonary artery (p=0.0001, r=0.382), Forced Expiratory Volume at 1 second (p=0.044, r=-0.153), DLCO (p=0.012, r=-190), the presence of premature ventricular beats (p=0.0001,r=0.281) and the 24hour derived standard deviation of NN, an index of HRV (p=0.001, p=-0.258). During a mean follow-up of 54±20 (range 1-101) months, 15 sarcoidosis patients (36.7%) died. Baseline BNP (69.00±48.58) of this group of patients was significantly elevated compared to the BNP levels (21.45±22.69) of those still alive (p<0.00001). BNP at a cutoff value of 28.35 pg/ml predicted all-cause mortality with a sensitivity of 85.8% and a specificity of 78.1% (area under the ROC curve, 0.857). Conclusion: BNP can be used as an additive predictor of all-cause mortality in patients with sarcoidosis.

2013 5th International Conference on Information and Communication Technologies, 2013

We propose a unique localization algorithm for MANETs: the mobile infrastructure-less networks wi... more We propose a unique localization algorithm for MANETs: the mobile infrastructure-less networks with support of static underlying wireless sensor network nodes. The algorithm has been designed with two stages for localizing the MANET. The first stage is the naive activation stage which acts as the bootstrap for the prediction stage. The predictive minimal energy consumption algorithm incorporates the information from the measured TOA (Time Of Arrival) to locate the mobile nodes. The experimental results and comparative analysis show that our system provides accurate localization of linearly moving MANET's using low power consumption of the underlying wireless sensor networks.

ASTL Sectech, 2013

Wireless sensor networks (WSNs) consist of many small wireless sensor nodes which are capable of ... more Wireless sensor networks (WSNs) consist of many small wireless sensor nodes which are capable of sensing data and sending it to base stations. WSNs face resource constraints including limitations on communication, power, memory capacity and computational power. Also, since they are frequently deployed in hostile environments and left unattended, they are vulnerable to several attacks such as sinkhole attacks. Sinkhole attacks occur when a compromised node attracts network traffic by advertising fake routing updates. This paper first describes the challenges in detecting sinkhole attacks in WSNs. This is followed by analyzing methods to detect and neutralize sinkholes.

Turk. J. …, 2012

Abstract: This research project was conducted to evaluate the use of different waste materials as... more Abstract: This research project was conducted to evaluate the use of different waste materials as potting media for the dwarf variety Dahlia hortensis' Figaro.'A total of 10 treatments were used where each treatment, consisting of 9 plants, was replicated 3 times. ...

Journal of Magnetic Resonance Imaging, 2014

To determine whether it is feasible to use solely an accelerated 4D phase-contrast magnetic reson... more To determine whether it is feasible to use solely an accelerated 4D phase-contrast magnetic resonance imaging (4D-PC MRI) acquisition to quantify net and regurgitant flow volume through each of the cardiac valves. Accelerated, 4D-PC MRI examinations performed between March 2010 through June 2011 as part of routine MRI examinations for congenital, structural heart disease were retrospectively reviewed and analyzed using valve-tracking visualization and quantification algorithms developed in Java and OpenGL. Excluding patients with transposition or single ventricle physiology, a total of 34 consecutive pediatric patients (19 male, 15 female; mean age 6.9 years; age range 10 months to 15 years) were identified. 4D-PC flow measurements were compared at each valve and against routine measurements from conventional cardiac MRI using Bland-Altman and Pearson correlation analysis. Inlet and outlet valve net flow were highly correlated between all valves (P = 0.940-0.985). The sum of forward flow at the outlet valve and regurgitant flow at the inlet valve were consistent with volumetric displacements in each ventricle (P = 0.939-0.948). These were also highly consistent with conventional planar MRI measurements with net flow (P = 0.923-0.935) and regurgitant fractions (P = 0.917-0.972) at the outlet valve and ventricular volumes (P = 0.925-0.965). It is possible to obtain consistent measurements of net and regurgitant blood flow across the inlet and outlet valves relying solely on accelerated 4D-PC. This may facilitate more efficient clinical quantification of valvular regurgitation.

Clinical Gastroenterology and Hepatology, 2012

BACKGROUND & AIMS: Acute ascending cholangitis usually is treated with antibiotics, and biliary d... more BACKGROUND & AIMS: Acute ascending cholangitis usually is treated with antibiotics, and biliary drainage is treated by endoscopic retrograde cholangiopancreatography (ERCP). We investigated the effects of the timing of ERCP on outcomes of patients with acute cholangitis factors that predict prolonged hospital stays, increased costs of hospitalization, and composite clinical outcomes (death, persistent organ failure, and admission to the intensive care unit). METHODS: We performed a retrospective analysis of data from 90 patients (mean age, 60 y; 48% female) admitted to Johns Hopkins Hospital from January 1994 to June 2010 who were diagnosed with acute cholangitis and underwent ERCP. A delayed ERCP was defined as one performed more than 72 hours after admission. Electronic and paper medical records were reviewed, and relevant data were abstracted. RESULTS: ERCP was performed successfully in 92% of the patients, at a mean time period of 38 hours after admission (14% of ERCPs were delayed). Factors that were associated independently with prolonged length of hospital stay (top 10%) included unsuccessful ERCP (odds ratio [OR], 52.5; P ϭ .002) and delayed ERCP (OR, 19.8; P ϭ .008). Factors associated with increased hospitalization cost (top 10%) included unsuccessful ERCP (OR, 33.8; P ϭ .004) and delayed ERCP (OR, 11.3; P ϭ .03). Factors associated with composite clinical outcome included age (OR, 1.1; P ϭ .01), total level of bilirubin (OR, 1.36; P ϭ .002), and delayed ERCP (OR, 7.8; P ϭ .04). CONCLUSIONS: Delayed and failed ERCP are associated with prolonged hospital stays and increased costs of hospitalization. Delayed ERCP is associated with composite clinical outcome (death, persistent organ failure, and/or intensive care unit stay). Older age and higher levels of bilirubin also are associated with patients' composite end point.

hgo.diva-portal.org

This paper tries to find the relationship between the compensation given to the chief executive o... more This paper tries to find the relationship between the compensation given to the chief executive officer and the performance of the company. Further, it tries to determine the influence of the size of the Board members on the pay scale of the executive. The data consisted of the largest thirty companies in Sweden for the period of 2004-2008. After controlling for firm size and growth opportunities, I find a negative and insignificant relationship between pay and performance. Contradictory to previous studies no correlation between large board size and chief executive officers compensation was found. This paper adds more empirical evidence to the idea of chief executives pay being independent of his performance.

2009 16th IEEE International Conference on Image Processing (ICIP), 2009

This paper demonstrates, to our best knowledge, the first attempt on gender and ethnicity identif... more This paper demonstrates, to our best knowledge, the first attempt on gender and ethnicity identification from silhouetted face profiles using a computer vision technique. The results achieved, after testing on 441 images, show that silhouetted face profiles have a lot of information, in particular, for ethnicity identification. Shape context based matching was employed for classification. The test samples were multi-ethnic. Average accuracy for gender was 71.20% and for ethnicity 71.66%. However, the accuracy was significantly higher for some classes, such as 83.41% for females (in case of gender identification) and 80.37% for East and South East Asians (in case of ethnicity identification).

... 2007 THESIS REPORT Analysis on Fixed and Mobile WiMAX By Umar Tariq Umer Naeem JilaniTauseef ... more ... 2007 THESIS REPORT Analysis on Fixed and Mobile WiMAX By Umar Tariq Umer Naeem JilaniTauseef Ahmed Siddiqui MS in Electrical Engineering majors in Telecommunications Project Advisor: Tommy Hult Deliverable: Report: 1 Volume Blekinge Institute of Technology ...

This work details the authors' efforts to push the baseline of expression recognition performance... more This work details the authors' efforts to push the baseline of expression recognition performance on a realistic database. Both subject-dependent and subject-independent emotion recognition scenarios are addressed in this work. These two happen frequently in real life settings. The approach towards solving this problem involves face detection, followed by key point identification, then feature generation and then finally classification. An ensemble of features comprising of Hierarchial Gaussianization (HG), Scale Invariant Feature Transform (SIFT) and Optic Flow have been incorporated. In the classification stage we used SVMs. The classification task has been divided into person specific and person independent emotion recognition. Both manual labels and automatic algorithms for person verification have been attempted. They both give similar performance.