V. Lupret - Academia.edu (original) (raw)
Papers by V. Lupret
Surgery in and around the Brain Stem and the Third Ventricle, 1986
Journal of Neurological Surgery Part B: Skull Base, 2012
Neuroradiology, 1978
From material of over 10,000 CTs a comparative study of computed tomography and ventriculography ... more From material of over 10,000 CTs a comparative study of computed tomography and ventriculography with contrast media was carried out. We examined 18 patients with suspected expansive lesions localized in the 3rd ventricle, aqueduct of Sylvius, and 4th ventricle. We have found that CT is the method of choice in these cases and that ventriculography should be reserved for those
Neuroscience, 1991
The effect of intracranial pressure on cerebrospinal fluid formation has been studied in cats by ... more The effect of intracranial pressure on cerebrospinal fluid formation has been studied in cats by ventricular perfusion with the aqueduct of Sylvius blocked (isolated ventricular perfusion). It has been found that intracranial pressure has a considerable effect on the rate of cerebrospinal fluid formation, while increases in pressure cause a significant and prolonged decrease in cerebrospinal fluid formation. The effect was observed in animals whether they were initially perfused under lower or under higher intracranial pressure. Cerebrospinal fluid absorption has been studied under the above conditions and it has been noted that the ventricles are capable of significant cerebrospinal fluid absorption, since in isolated ventricles cerebrospinal fluid formation and absorption were in balance at physiological intracranial pressure. In addition, cerebrospinal fluid formation rate within the isolated brain ventricles has been compared with the formation rate in the whole cerebrospinal fluid system.
Lijec̆nic̆ki vjesnik
In this review current views of etiology, pathophysiology, essential data in clinical course and ... more In this review current views of etiology, pathophysiology, essential data in clinical course and modes of treatment of non-traumatic intracranial hemorrhages are presented. Aneurysms, vascular malformations and "spontaneous hemorrhages" (caused by atherosclerosis accompanied by hypertension or systemic diseases) are most common causes of non-traumatic intracranial hemorrhages. These hemorrhages are rarely caused by rupture of intracranial tumor vessels. Personal experiences in the treatment of patients suffering from intracranial hemorrhage caused by rupture of aneurysm, vascular malformation or artherosclerotic vessel after sudden raise of blood pressure are presented. Current modes of treatment based on personal experience and experiences of well-known authorities are given.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, Jan 30, 2003
We report a case with atypical pattern and time course of inflammatory response after partial emb... more We report a case with atypical pattern and time course of inflammatory response after partial embolization of a cerebral arteriovenous malformation with N-butylcyanoacrylate (NBCA), examined by immunohistochemical analysis. This pathomorphological finding of permanent acute inflammation has not been previously reported in humans.
Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti, 1993
Cranial base lesions present a great challenge even to the most skilled neurosurgeon due to the d... more Cranial base lesions present a great challenge even to the most skilled neurosurgeon due to the difficulty of gaining access to the cranial base, the complex anatomical relations, hips of neurovascular structures involved in the pathology of the cranial base and bone destruction caused by tumors leaving intracranial space open to the respiratory and digestive tracts. With continuous advancements in microsurgical techniques and neuroradiological imaging, the removal of cranial base lesions has became a reality. Mortality rates of 50% or greater are today reduced to 10%, and previously very high morbidity rates today are acceptably low. The greatest acknowledgement in the advancement of cranial base lesions management must be given to the teamwork of neurosurgeons, radiologists, head and neck surgeons, otorhinolaryngologists and neuroophthalmologists.
Acta medica Iugoslavica, 1983
Clinical Neurology and Neurosurgery, 1997
Clinical Neurology and Neurosurgery, 1997
Archives of Medical Research, 2002
Seven cases of neurocysticercosis and three cases of neuroechinococcosis with symptoms of elevate... more Seven cases of neurocysticercosis and three cases of neuroechinococcosis with symptoms of elevated intracranial pressure requiring urgent neurosurgical treatment are described. No neuroradiologic procedure established exact diagnosis preoperatively; this was achieved by pathohistologic analysis of bioptic material. Ten patients with duration of clinical symptoms ranging from 1 week to 1 month were operated on at the Department of Neurosurgery of Sestre Milosrdnice University Hospital in Zagreb, Croatia during the period 1988-2000. On receipt, bioptical material was examined pathohistologically at the Ljudevit Jurak Clinical Department of Pathology of the same hospital. We compared our data with facts collected by reviewing the pertinent literature over the past 10 years. The most common localization of parasitic cysts in our study was posterior cranial fossa, i.e., subtentorial, which, according to the literature, is a rare localization. Due to this unusual localization, dominant clinical symptoms included elevated intracranial pressure, requiring urgent surgical removal of parasitic cysts. With the exception of the epidemiologic aspect, cerebral cysticercosis and echinococcosis are important as a true diagnostic and therapeutic problem. These human parasitic zoonoses are rarely diagnosed preoperatively despite newly developed neuroradiologic and serologic methods, especially in cases of primary appearance in brain when exact diagnosis reveals adequate surgical removal with subsequent complete recovery.
Acta Neurochirurgica, 1980
A nine-weeks-old infant with haemophilia A developed an intracerebral haematoma. Intracranial ope... more A nine-weeks-old infant with haemophilia A developed an intracerebral haematoma. Intracranial operation and removal of the haematoma were performed safely under the cover of highly potent AHF cryoprecipitate. Computerized tomography of the brain is very useful for neurosurgical care of the haemophiliac patients as a noninvasive and atraumatic method of examination. The literature of intracranial operations in infants with haemophilia A under the age of one year is reviewed.
Acta Neurochirurgica, 1993
Eleven patients with venous angiomas, 6 males and 5 females ranging in age from 4 to 58, are pres... more Eleven patients with venous angiomas, 6 males and 5 females ranging in age from 4 to 58, are presented. Four patients presented with intracerebral haematoma and 3 patients had associated cavernous angioma, respectively. Patients with intracerebral haematoma had signs and symptoms due to the localization of the haematoma. The other patients presented with headache, seizures, vertigo, ataxia and mental disturbances. Pre-operative diagnosis was based on computerized tomography, magnetic resonance imaging and cerebral angiography. In 9 surgical cases it was confirmed by histopathological examination of operative specimens. After establishing the type, size and location of the lesion decision for operative treatment was made in nine cases, in four of them because of the presence of an intracerebral haematoma and in 5 of them due to severe disability. Eight of these 9 patients recovered completely and one improved. No severe cerebral oedema was encountered after converging medullary veins were excised and main draining veins partially coagulated. In this small series we encountered an unexpectedly large percentage of venous angiomas causing intracerebral haemorrhage which are commonly considered more benign than other vascular malformations. After reviewing previously reported cases of venous angiomas causing intracerebral haemorrhage and severe neurological deficit we think that the term "benign" is worth reconsidering. We propose a thorough examination of each case of venous angioma and the operative treatment when appropriate taking into account patients state and location of angioma.
Acta Neurochirurgica, 2007
We present a case of the 31-year-old male patient who complained of weakness in both legs and pro... more We present a case of the 31-year-old male patient who complained of weakness in both legs and progressed slowly. Neuroimagine of the thoracic spine showed an intraspinal, extradural mass lesion, measuring 5.3Â 1.2 cm at the Th1-Th3 level. Histologically the lesion was a spindle cell haemangioma composed of dilated vascular spaces and a proliferation of bland appearing interspersed spindle cells. Immunohistochemical analysis was diffusely positive for VIM, SMA and focally for CD34. This lesion is uncommon and shows a predilection for distal extremities. Spindle cell haemangioma within the spine has not been previously reported in the literature.
Neurologia croatica: glasilo Udruzenja neurologa Jugoslavije = official journal of Yugoslav Neurological Association
A case of cavernous angioma situated in the left cavernous sinus is presented. Occasional difficu... more A case of cavernous angioma situated in the left cavernous sinus is presented. Occasional difficulties in accessing correct preoperative diagnosis with computerized tomography and angiography were encountered. Intraoperative relationships of neural and vascular structures of the cavernous sinus and tumor mass are described. An "en mass" extirpation was achieved without further neurological damage. A possible origin of cavernous angioma from the 6th cranial nerve is discussed.
Surgery in and around the Brain Stem and the Third Ventricle, 1986
Journal of Neurological Surgery Part B: Skull Base, 2012
Neuroradiology, 1978
From material of over 10,000 CTs a comparative study of computed tomography and ventriculography ... more From material of over 10,000 CTs a comparative study of computed tomography and ventriculography with contrast media was carried out. We examined 18 patients with suspected expansive lesions localized in the 3rd ventricle, aqueduct of Sylvius, and 4th ventricle. We have found that CT is the method of choice in these cases and that ventriculography should be reserved for those
Neuroscience, 1991
The effect of intracranial pressure on cerebrospinal fluid formation has been studied in cats by ... more The effect of intracranial pressure on cerebrospinal fluid formation has been studied in cats by ventricular perfusion with the aqueduct of Sylvius blocked (isolated ventricular perfusion). It has been found that intracranial pressure has a considerable effect on the rate of cerebrospinal fluid formation, while increases in pressure cause a significant and prolonged decrease in cerebrospinal fluid formation. The effect was observed in animals whether they were initially perfused under lower or under higher intracranial pressure. Cerebrospinal fluid absorption has been studied under the above conditions and it has been noted that the ventricles are capable of significant cerebrospinal fluid absorption, since in isolated ventricles cerebrospinal fluid formation and absorption were in balance at physiological intracranial pressure. In addition, cerebrospinal fluid formation rate within the isolated brain ventricles has been compared with the formation rate in the whole cerebrospinal fluid system.
Lijec̆nic̆ki vjesnik
In this review current views of etiology, pathophysiology, essential data in clinical course and ... more In this review current views of etiology, pathophysiology, essential data in clinical course and modes of treatment of non-traumatic intracranial hemorrhages are presented. Aneurysms, vascular malformations and "spontaneous hemorrhages" (caused by atherosclerosis accompanied by hypertension or systemic diseases) are most common causes of non-traumatic intracranial hemorrhages. These hemorrhages are rarely caused by rupture of intracranial tumor vessels. Personal experiences in the treatment of patients suffering from intracranial hemorrhage caused by rupture of aneurysm, vascular malformation or artherosclerotic vessel after sudden raise of blood pressure are presented. Current modes of treatment based on personal experience and experiences of well-known authorities are given.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, Jan 30, 2003
We report a case with atypical pattern and time course of inflammatory response after partial emb... more We report a case with atypical pattern and time course of inflammatory response after partial embolization of a cerebral arteriovenous malformation with N-butylcyanoacrylate (NBCA), examined by immunohistochemical analysis. This pathomorphological finding of permanent acute inflammation has not been previously reported in humans.
Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti, 1993
Cranial base lesions present a great challenge even to the most skilled neurosurgeon due to the d... more Cranial base lesions present a great challenge even to the most skilled neurosurgeon due to the difficulty of gaining access to the cranial base, the complex anatomical relations, hips of neurovascular structures involved in the pathology of the cranial base and bone destruction caused by tumors leaving intracranial space open to the respiratory and digestive tracts. With continuous advancements in microsurgical techniques and neuroradiological imaging, the removal of cranial base lesions has became a reality. Mortality rates of 50% or greater are today reduced to 10%, and previously very high morbidity rates today are acceptably low. The greatest acknowledgement in the advancement of cranial base lesions management must be given to the teamwork of neurosurgeons, radiologists, head and neck surgeons, otorhinolaryngologists and neuroophthalmologists.
Acta medica Iugoslavica, 1983
Clinical Neurology and Neurosurgery, 1997
Clinical Neurology and Neurosurgery, 1997
Archives of Medical Research, 2002
Seven cases of neurocysticercosis and three cases of neuroechinococcosis with symptoms of elevate... more Seven cases of neurocysticercosis and three cases of neuroechinococcosis with symptoms of elevated intracranial pressure requiring urgent neurosurgical treatment are described. No neuroradiologic procedure established exact diagnosis preoperatively; this was achieved by pathohistologic analysis of bioptic material. Ten patients with duration of clinical symptoms ranging from 1 week to 1 month were operated on at the Department of Neurosurgery of Sestre Milosrdnice University Hospital in Zagreb, Croatia during the period 1988-2000. On receipt, bioptical material was examined pathohistologically at the Ljudevit Jurak Clinical Department of Pathology of the same hospital. We compared our data with facts collected by reviewing the pertinent literature over the past 10 years. The most common localization of parasitic cysts in our study was posterior cranial fossa, i.e., subtentorial, which, according to the literature, is a rare localization. Due to this unusual localization, dominant clinical symptoms included elevated intracranial pressure, requiring urgent surgical removal of parasitic cysts. With the exception of the epidemiologic aspect, cerebral cysticercosis and echinococcosis are important as a true diagnostic and therapeutic problem. These human parasitic zoonoses are rarely diagnosed preoperatively despite newly developed neuroradiologic and serologic methods, especially in cases of primary appearance in brain when exact diagnosis reveals adequate surgical removal with subsequent complete recovery.
Acta Neurochirurgica, 1980
A nine-weeks-old infant with haemophilia A developed an intracerebral haematoma. Intracranial ope... more A nine-weeks-old infant with haemophilia A developed an intracerebral haematoma. Intracranial operation and removal of the haematoma were performed safely under the cover of highly potent AHF cryoprecipitate. Computerized tomography of the brain is very useful for neurosurgical care of the haemophiliac patients as a noninvasive and atraumatic method of examination. The literature of intracranial operations in infants with haemophilia A under the age of one year is reviewed.
Acta Neurochirurgica, 1993
Eleven patients with venous angiomas, 6 males and 5 females ranging in age from 4 to 58, are pres... more Eleven patients with venous angiomas, 6 males and 5 females ranging in age from 4 to 58, are presented. Four patients presented with intracerebral haematoma and 3 patients had associated cavernous angioma, respectively. Patients with intracerebral haematoma had signs and symptoms due to the localization of the haematoma. The other patients presented with headache, seizures, vertigo, ataxia and mental disturbances. Pre-operative diagnosis was based on computerized tomography, magnetic resonance imaging and cerebral angiography. In 9 surgical cases it was confirmed by histopathological examination of operative specimens. After establishing the type, size and location of the lesion decision for operative treatment was made in nine cases, in four of them because of the presence of an intracerebral haematoma and in 5 of them due to severe disability. Eight of these 9 patients recovered completely and one improved. No severe cerebral oedema was encountered after converging medullary veins were excised and main draining veins partially coagulated. In this small series we encountered an unexpectedly large percentage of venous angiomas causing intracerebral haemorrhage which are commonly considered more benign than other vascular malformations. After reviewing previously reported cases of venous angiomas causing intracerebral haemorrhage and severe neurological deficit we think that the term "benign" is worth reconsidering. We propose a thorough examination of each case of venous angioma and the operative treatment when appropriate taking into account patients state and location of angioma.
Acta Neurochirurgica, 2007
We present a case of the 31-year-old male patient who complained of weakness in both legs and pro... more We present a case of the 31-year-old male patient who complained of weakness in both legs and progressed slowly. Neuroimagine of the thoracic spine showed an intraspinal, extradural mass lesion, measuring 5.3Â 1.2 cm at the Th1-Th3 level. Histologically the lesion was a spindle cell haemangioma composed of dilated vascular spaces and a proliferation of bland appearing interspersed spindle cells. Immunohistochemical analysis was diffusely positive for VIM, SMA and focally for CD34. This lesion is uncommon and shows a predilection for distal extremities. Spindle cell haemangioma within the spine has not been previously reported in the literature.
Neurologia croatica: glasilo Udruzenja neurologa Jugoslavije = official journal of Yugoslav Neurological Association
A case of cavernous angioma situated in the left cavernous sinus is presented. Occasional difficu... more A case of cavernous angioma situated in the left cavernous sinus is presented. Occasional difficulties in accessing correct preoperative diagnosis with computerized tomography and angiography were encountered. Intraoperative relationships of neural and vascular structures of the cavernous sinus and tumor mass are described. An "en mass" extirpation was achieved without further neurological damage. A possible origin of cavernous angioma from the 6th cranial nerve is discussed.