Vaibhav Ingle - Academia.edu (original) (raw)

Papers by Vaibhav Ingle

The Journal of Obstetrics and Gynecology of India

Melioidosis is caused by Burkholderia pseudomallei, a gram negative bacterium which is an oxidase... more Melioidosis is caused by Burkholderia pseudomallei, a gram negative bacterium which is an oxidase positive, motile bacillus present in soil and water of tropical and subtropical areas. It can survive in extreme conditions for years and can infect both humans as well as animals. It is rarely transmitted from human to humans [1], however few cases of nosocomial infections have been reported. It is an emerging problem in India. The persons who are immune compromised or having diabetes mellitus, chronic liver disease, chronic alcoholism, chronic lung disease or occupational exposure are prone to develop it, though melioidosis can develop in persons without risk factors also. The spectrum of disease, severity and outcome varies depending upon the presence and absence of risk factors. The incubation period varies from 1 to 21 days with an average of 9 days. The acute infection can present as fatal septicaemia with septic shock, pneumonia, and acute respiratory distress syndrome, thrombosis of vessels, abscesses in the spleen, liver, lungs, kidneys, prostate, subcutaneous abscess, osteomyelitis and septic arthritis. The chronic infection may present with nonspecific symptoms to pyrexia of unknown origin, which makes the diagnosis difficult. Transmission of infection can occur via inhalation, aspiration and occasionally by percutaneous inoculation or ingestion. Cases of pneumonia following presumptive inoculating skin injuries are well documented, suggesting that the organism can reach the lungs via the haematogenous route [2]. Laboratory-acquired infections and iatrogenic infections from contaminated hospital or surgical equipment occasionally occur. Melioidosis during postpartum period is very rare and to best of our knowledge only one case of melioidosis following lower segment caesarean section (LSCS) was found while reviewing the available literature [3]. Here we report a case of a young lady who developed acute disseminated melioidosis after LSCS surgery.

International Journal of Advance Research and Innovative Ideas in Education, 2021

Cureus, 2022

Background: Cirrhosis progression varies greatly from patient to patient due to a variety of fact... more Background: Cirrhosis progression varies greatly from patient to patient due to a variety of factors, including hepatic reserve, cirrhosis etiology, and the presence of hepatocellular cancer. As a result, determining a prognosis in a patient with cirrhosis remains a difficult task. For nearly three decades, the Child-Pugh score (CPS) has been the gold standard for determining the prognosis of cirrhosis. In the last two decades, many prognostic models and scores like a model for end-stage liver disease (MELD), chronic liver failuresequential organ failure assessment (CLIF-SOFA) score, peripheral blood lymphocyte to monocyte ratio (LMR) have been presented to predict prognosis in patients with cirrhosis and to choose the best therapy option. The aim of our study is to determine which score is more effective in predicting three-month mortality and whether these scores are equally effective in predicting short-term outcomes. Materials & methods: In this hospital-based longitudinal study, we analyzed 140 patients with cirrhosis of liver visiting All India Institute of Medical Sciences Bhopal between July 2019 and July 2020. All the 140 patients were followed up for three months to establish short-term outcomes. The blood investigations were done at the time of presentation from all the patients and after three months in the survivors. Various scores were calculated. Results: The majority of patients (47%) were in Child-Pugh class C. Mean MELD score was 13.54, LMR score was 1.96 and CLIF-SOFA score was 5. The total bilirubin, serum creatinine, international normalized ratio (INR), total leukocyte count, absolute monocyte count, CPS, MELD, CLIF-SOFA were significantly higher in a non-surviving group as compared to the surviving group, whereas the albumin and LMR significantly decreased in the non-surviving group. On performing multivariate regression, LMR and CLIF-SOFA were significant independent risk factors of mortality after adjusting for confounding factors. All the parameters had significant discriminatory power to predict mortality. Discriminatory power of CLIF-SOFA (AUC 0.808; 95% CI: 0.733 to 0.870) was excellent and discriminatory power of CPS (AUC 0.792; 95% CI: 0.716 to 0.856), MELD score (AUC 0.765; 95% CI: 0.685 to 0.832) and LMR (AUC 0.75; 95% CI: 0.669 to 0.819) was acceptable. Among all the parameters, CLIF-SOFA was the best predictor of mortality at a cutoff point of >5 with 80.80% chances of correctly predicting mortality. Conclusion: The significant morbidity and mortality indicators are high total bilirubin, high creatinine, high INR, high TLC, low platelet count, and low albumin. Among the various scores, CLIF-SOFA is a better predictor of mortality and morbidity. Low LMR and high CLIF-SOFA are significant independent risk factors of mortality at three months.

International Journal of Advance Research and Innovative Ideas in Education, 2017

“What a difference a second makes” – a quote from an empowered employee. Just one second over a t... more “What a difference a second makes” – a quote from an empowered employee. Just one second over a ten second continuous cycle can mean your line runs consistently 10% faster, the difference between comfortably achieving tight production schedules or continually being capacity constrained.[1] This work presents a new approach for the reduction of process cycle time and its impact on a company's competitive edge. Reduction in cycle time has been gaining significant attention in recent times. The shorter cycle times effect in higher consumer satisfaction, lower manufacturing rate, higher yield, and better potential given tool inventory and facility constraints. This research paper provides a brief review of core approaches related to cycle time and also describes a methodology for cycle time reduction in any manufacturing and automobile production industry. It includes the assessment and potential gains of the projected cycle time reduction methodology.[3]

1Assistant Professor, Department of Medicine, All India Institute of Medical Sciences, Bhopal, Ma... more 1Assistant Professor, Department of Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India, 2Professor, Department of Medicine, Shri Aurobindo Institute of Medical sciences, Indore, Madhya Pradesh India, 3Associate Professor, Department of Medicine, Shri Aurobindo Institute of Medical sciences, Indore, Madhya Pradesh, India, 4Resident, Department of Medicine, Shri Aurobindo Institute of Medical sciences, Indore, Madhya Pradesh, India

Journal of emerging technologies and innovative research, 2017

Recent 20 th century, aluminum and aluminum alloys drastically used in automotive industries like... more Recent 20 th century, aluminum and aluminum alloys drastically used in automotive industries like automobile and aerospace locomotive industries because of its various mechanical properties like strength malleability and formability corrosion resistance, electrical and thermal conductivity good machinability. The microstructure of corresponding alloy and intermediate phase compounds during formation of corresponding alloy change the addition of alloying element which effect on mechanical properties. In present research paper shows the use of aluminum and aluminum alloys with containing other alloy elements, with their effects and micro structural behavior and wear behavior at various speed load condition.

Indian Journal of Nephrology, 2021

Nephrocalcinosis (NC) is the augmented calcium content within the renal parenchyma. Its pathogene... more Nephrocalcinosis (NC) is the augmented calcium content within the renal parenchyma. Its pathogenesis mainly involves hypercalciuria. The presence of medullary NC provides a window to the clinician for the diagnosis of many important diseases. In this case series, we highlight three diseases that could be diagnosed with a high index of suspicion and detailed evaluation after their presentation as medullary NC.

In urban India, about 35-40% of all adults have hypertension and about 10-15% have diabetes melli... more In urban India, about 35-40% of all adults have hypertension and about 10-15% have diabetes mellitus. National Program for Prevention and Control of Diabetes, Cancer and Stroke (NPCDCS) launched by Government of India has envisaged to screen all adults aged 30 years and above for presence of hypertension and diabetes mellitus in the community through population-based screening, initiate positively screened and diagnosed on drug therapy, and follow them up for treatment adherence. In this context, the current study aims to estimate burden of high cardiovascular disease (CVD) risk and to evaluate feasibility of community health workers-based strategies in reducing CVD among adults living in urban slums. We have identified and trained CHWs from within the urban slum communities in Bhopal, in chronic disease identification, skills in self-care and adherence promotion skills. At-risk individuals were linked to public health facilities as outlined under NPCDCS. Primary outcome is assessme...

BMJ Case Reports, 2021

Eight-and-a-half syndrome is a rare entity characterised by conjugate horizontal gaze palsy, ipsi... more Eight-and-a-half syndrome is a rare entity characterised by conjugate horizontal gaze palsy, ipsilateral internuclear ophthalmoplegia and ipsilateral lower motor neuron type facial palsy. It is due to a lesion affecting median longitudinal fasciculus, paramedian pontine reticular formation and facial nerve fascicle on the same side at the level of pons. The diagnosis is easily missed as it needs detailed ocular movement examination. It is mainly caused due to infarction or demyelinating conditions. We are reporting an interesting case of a 54-year-old man with right-side eight-and-a-half syndrome due to acute ischaemic stroke and ST-elevation myocardial infarction of the inferior wall.

Journal of Evolution of Medical and Dental Sciences, Feb 5, 2014

Superior mesenteric artery (SMA) syndrome is a rare acquired disorder in which an acute angulatio... more Superior mesenteric artery (SMA) syndrome is a rare acquired disorder in which an acute angulation of SMA causes compression and obstruction of the third part of the duodenum between the SMA and the aorta. The diagnosis is usually made by exclusion. A large number of debilitating conditions leading to a loss of fatty tissue such as anorexia nervosa, malabsorption, or hyper catabolic states like burns, major surgery, severe injuries, or malignancies can cause this syndrome. To our knowledge there are no cases reported in the Indian literature, though many such cases are being diagnosed and successfully treated the world over. We recently diagnosed and successfully treated a patient of S.M.A. syndrome in Shri Aurobindo Institute of Medical Sciences, Medical College and PostGraduate Institute. We take the opportunity to review the literature on S.M.A. syndrome.

This modern era's high technological improvements present manufacturers and other organizations w... more This modern era's high technological improvements present manufacturers and other organizations with a plethora of Management Information Systems (MISs) which makes them face challenges when choosing a corporate information system. High initial investment in setting up the information systems make it very difficult for companies to adopt new systems as they come into market before realizing a reasonable return from the previous system. In line with these concerns, a methodology for building a Balanced Scorecard module as a strategic management platform that can be integrated smoothly into already existing information system such as MRP/ERP is presented. The paper uses a case study of a manufacturing company based in Zimbabwe. Various manufacturing based metrics are reviewed with the main intent of showing how these can be tracked in a computerized platform. Sample data extracted from the production system is used to test the built system. The paper shows a methodology for software design, setting up and adopting a BSC system. The proposed approach is used to design a computerized BSC system for the case study company, which incorporates a BSC dashboard for the four main perspectives derived from various operational metrics.

International Journal of Research in Medical Sciences, 2017

Background: Upper airway resistance syndrome (UARS) is a recent concept introduced among sleep di... more Background: Upper airway resistance syndrome (UARS) is a recent concept introduced among sleep disordered breathing (chronic snoring and Obstructive sleep apnea) disorders. UARS also presents with excessive daytime sleepiness (EDS), which is associated with impaired social functioning, work performance and driving ability. However, UARS is not merely a continuum between chronic snoring and obstructive sleep apnea (OSA). Not only UARS patients have equal gender distribution and thin body habitus but they also do not fulfil Polysomnographic criteria of OSA. UARS diagnosis requires oesophageal manometry for diagnosing increased respiratory efforts against increased upper airway resistance (without complete cessation of airflow or hypoxia) and correlating it with EEG arousals to mark an event. Oesophageal manometry is invasive and uncomfortable, therefore, non-invasive means are desirable for evaluation of UARS. The aim of the study is to evaluate the patients with EDS for UARS non-inva...

International journal of applied & basic medical research

Depression, especially in concurrence with chronic medical disorders, is highly prevalent worldwi... more Depression, especially in concurrence with chronic medical disorders, is highly prevalent worldwide. An average between 9.3% and 23% of patients with one or more chronic disease have co-morbid depression. This comorbid depression has the worst health scores of all the disease states. Despite this, patients with chronic medical disorders are not commonly screened for depression. Lack of objective screening by health-care providers as well as lack of infrastructure (time/space/personnel) probably contributes to gross underdiagnosis of depression. This issue can be addressed using short objective depression screening score (Patient Health Questionnaire-9 [PHQ-9]) (validated in native languages, e.g., Hindi) and paperless self-administered interface on handheld computer (tablet), which is the objective of the study. One hundred consecutive patients with chronic medical disorders visiting our medicine outpatient department were screened for depression using tablets with PHQ-9 Hindi on a ...

International Journal of Engineering Research and Applications, 2017

Many industry aims to improve quality as well as productivity of manufacturing product. So need t... more Many industry aims to improve quality as well as productivity of manufacturing product. So need to number of process parameter to must controlled while casting process, so there are no of uncertainty and defects are face by organizations. In casting process industries are need to technical solution to minimize the uncertainty and defects. In this review paper to represent various casting defects and root causes for engine parts while casting process. Also provide preventive action to improve quality as well as productivity an industrial level.

Indian Journal of Nephrology, 2016

Superior Mesenteric Artery Syndrome a Review, May 2, 2014

 Abstract— The vision of a landscape of heterogeneous web services deployed as encapsulated busi... more  Abstract— The vision of a landscape of heterogeneous web services deployed as encapsulated business software assets in the Internet is currently becoming a reality as part of the Semantic Web. When pro-active agents handle the context-aware discovery, acquisition, composition, management of applications services and data, ensuring the security if customers data become a principle task. In this paper we propose neoteric way web services and security. A methodology based on type-based information flow to control the security of dynamically computed data and their proliferation to other web services. The approach is based on the following trine guidelines: (1)The business and security concern of integrated web services are separated and building them independently.(2)Runtime modification of integrated web services.(3)Providing compartmentalization so that one service can not affect another. We are developing flight system to demonstrate the feasibility of our approach.