Veeru Kasivisvanathan - Academia.edu (original) (raw)
Papers by Veeru Kasivisvanathan
European Urology Supplements, 2013
European Urology Supplements, 2012
BJU International, 2015
Iodinated contrast agents (ICA) are an essential part of the urologist&am... more Iodinated contrast agents (ICA) are an essential part of the urologist's everyday practice, allowing enhanced imaging of the urinary tract. Contrast is administered directly into the urinary tract during retrograde pyelograms, JJ stent insertion, ureterorenoscopy, urethrography and cystography. Contrast can also be administered intravenously, for example during CT urogram studies in the investigation of haematuria. Increasingly, patients are labelled as having a contrast "allergy" when in fact this is a misnomer as it is not a true allergy. This article is protected by copyright. All rights reserved.
World Journal of Urology, 2015
Der Urologe. Ausg. A, 2015
Focal therapy is a treatment strategy for men with localized prostate cancer that may serve as an... more Focal therapy is a treatment strategy for men with localized prostate cancer that may serve as an alternative option to radical therapy. A number of minimally invasive ablative technologies are available to deliver treatment, and the energies most commonly used include high-intensity focused ultrasound and cryotherapy. The benefit of a tissue-preserving approach is the limitation of damage to key structures such as the neurovascular bundles, external urinary sphincter, rectal mucosa and bladder neck. This in turn minimizes side effects typically associated with radical therapies whilst also aiming to maintain oncological control. Over 30 single-centre studies of focal therapy have been published to date reporting excellent continence rates, good potency rates and acceptable short-term oncological outcomes. However, there are a number of controversial aspects associated with focal therapy including the index lesion hypothesis, patient selection criteria, assessment of treatment effec...
European Urology Supplements, 2013
European Urology Supplements, 2012
Urologic Oncology: Seminars and Original Investigations, 2015
Journal of Vascular Surgery, 2011
The Journal of Urology, 2013
The Journal of Urology, 2013
The International Journal of Tuberculosis and Lung Disease, 2012
European Urology Supplements, 2013
European Urology Supplements, 2012
BJU International, 2015
Iodinated contrast agents (ICA) are an essential part of the urologist&am... more Iodinated contrast agents (ICA) are an essential part of the urologist's everyday practice, allowing enhanced imaging of the urinary tract. Contrast is administered directly into the urinary tract during retrograde pyelograms, JJ stent insertion, ureterorenoscopy, urethrography and cystography. Contrast can also be administered intravenously, for example during CT urogram studies in the investigation of haematuria. Increasingly, patients are labelled as having a contrast "allergy" when in fact this is a misnomer as it is not a true allergy. This article is protected by copyright. All rights reserved.
World Journal of Urology, 2015
Der Urologe. Ausg. A, 2015
Focal therapy is a treatment strategy for men with localized prostate cancer that may serve as an... more Focal therapy is a treatment strategy for men with localized prostate cancer that may serve as an alternative option to radical therapy. A number of minimally invasive ablative technologies are available to deliver treatment, and the energies most commonly used include high-intensity focused ultrasound and cryotherapy. The benefit of a tissue-preserving approach is the limitation of damage to key structures such as the neurovascular bundles, external urinary sphincter, rectal mucosa and bladder neck. This in turn minimizes side effects typically associated with radical therapies whilst also aiming to maintain oncological control. Over 30 single-centre studies of focal therapy have been published to date reporting excellent continence rates, good potency rates and acceptable short-term oncological outcomes. However, there are a number of controversial aspects associated with focal therapy including the index lesion hypothesis, patient selection criteria, assessment of treatment effec...
European Urology Supplements, 2013
European Urology Supplements, 2012
Urologic Oncology: Seminars and Original Investigations, 2015
Journal of Vascular Surgery, 2011
The Journal of Urology, 2013
The Journal of Urology, 2013
The International Journal of Tuberculosis and Lung Disease, 2012
Current vascular pharmacology, 2012
The annual rate of ipsilateral stroke associated with asymptomatic carotid stenosis has fallen fr... more The annual rate of ipsilateral stroke associated with asymptomatic carotid stenosis has fallen from 2-4% to <1% in the last 20 years due to improvements in medical therapy. The fundamental benefits of this are relevant to whether patients undergo revascularisation or not. We aimed to evaluate existing international guidelines for the management of carotid stenosis, identifying important similarities and differences. The websites of the American Heart Association, Society for Vascular Surgery, European Society for Cardiology, European Society for Vascular Surgery, British Cardiovascular Society and UK Vascular Society were searched for guidelines relating to primary prevention for asymptomatic atherosclerotic carotid disease in September 2011 and independently reviewed by 2 authors. The following guidelines were identified and compared: The Joint British Societies 2nd (JBS2) 2005 guideline, the 4th European Society for Cardiology (ESC) 2007 guideline, the joint American Heart Association/Society for Vascular Surgery (AHA/SVS) guideline 2011 and subsequent 2011 SVS update, the American Heart Association (AHA) prevention of stroke guideline 2010, the AHA secondary prevention for atherosclerotic coronary and vascular disease 2011 update, and the European Society for Vascular Surgery (ESVS) Section A carotid guideline. There was no UK guidance from its vascular society. Important differences were evident in methods of risk assessment, treatment targets for blood pressure and low density lipoprotein cholesterol, and the use of anti-platelet agents. These differences are highlighted in 2 case scenarios. There is now clear, evidence based guidance from British, European and US cardiovascular bodies regarding optimal targets for risk factor modification. These can be adopted as standard operating procedure for clinical practice and the medical arms of carotid interventional trials. In the future imaging biomarkers may help provide an understanding of the risk of an individual carotid lesion to help guide therapy.
Journal of vascular surgery, 2012
Background: Treatment of head and neck malignancy commonly involves radiotherapy, which is associ... more Background: Treatment of head and neck malignancy commonly involves radiotherapy, which is associated with the development of carotid artery stenosis. There is little evidence to guide clinicians on how to intervene in significant postradiotherapy carotid stenosis. This systematic review collated data pertaining to perioperative outcomes of carotid artery surgery and carotid stenting in postradiotherapy carotid stenosis to aid the clinical decision-making process. Methods: A systematic review of the literature, adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 guidelines, was performed. We screened 575 articles related to carotid artery surgery or stenting in postradiotherapy carotid stenosis, from which 21 studies were included for quantitative analysis. The primary outcome was stroke or death <30 days of the procedure. Secondary outcomes included cranial nerve injury, restenosis, stroke, and death at >30 days. Results: Nine publications recorded 211 surgical procedures in 179 patients. In symptomatic patients, the 30-day mortality rate was 2.6% and the stroke or death rate was 2.7%. In asymptomatic patients, the 30-day mortality rate was 0% and the stroke or death rate was 1.1%. Permanent cranial nerve palsy was experienced by 0.6% of patients. Twelve publications recorded 510 carotid artery stenting procedures in 482 patients. In symptomatic patients, the 30-day mortality rate was 5.1%, and the stroke or death rate was 5.1%. In asymptomatic patients, the 30-day mortality rate was 1.4%, and the stroke or death rate was 2.1%. There was no statistically significant difference in 30-day stroke or death rate between surgical revascularization and carotid artery stenting in all (odds ratio [OR], 0.54; 95% confidence interval [CI] 0.17-1.70; P ؍ .43), symptomatic (OR, 0.52; 95% CI, 0.14-1.98; P ؍ .38), or asymptomatic patients (OR, 0.55; 95% CI, 0.06-5.42; P ؍ .99). Conclusions: The published outcomes from high-volume centers demonstrate that surgical revascularization and stenting are both technically feasible in postradiotherapy carotid stenosis and have similar safety profiles to nonirradiated necks. Radiation should therefore not be considered a contraindication to surgical intervention. ( J Vasc Surg 2012;ⅢⅢ:ⅢⅢⅢ.)
Current Problems in Cardiology, Jan 1, 2011
European Journal of Surgical Oncology, Volume 37, Issue 11, Pages 989-990, November 2011, Authors... more European Journal of Surgical Oncology, Volume 37, Issue 11, Pages 989-990, November 2011, Authors:Veeru Kasivisvanathan; A. Thapar; J. Shalhoub; Y. Oskrochi; H. Wasan; E. Leen.