Vefa Erbasan - Academia.edu (original) (raw)

Papers by Vefa Erbasan

Research paper thumbnail of Evaluation of the relationship between suicidal behavior and the sirt1 gene in patients with schizophrenia

Research paper thumbnail of P.0416 Modafinil increases the number of hypomanic symptoms in patients with bipolar depressive symptoms?

European Neuropsychopharmacology, 2021

Research paper thumbnail of P.613 Comparison of clinical and biochemical features between bipolar patients on mood stabilizer alone or combination treatment

European Neuropsychopharmacology, 2019

Research paper thumbnail of P.0076 Evaluation of the staging after the first manic episode in patients with bipolar disorder

European Neuropsychopharmacology, 2021

Research paper thumbnail of Bi̇r Üni̇versi̇te Bahar Şenli̇kleri̇ne Katilanlarin Hava Ki̇rli̇li̇ği̇ Bi̇lgi̇ Düzeyi̇ni̇n Araştirilmasi

Giris ve Amac: Toplum sagligini tehdit eden sorunlarin basinda hava kirliligi gelmektedir. Hava k... more Giris ve Amac: Toplum sagligini tehdit eden sorunlarin basinda hava kirliligi gelmektedir. Hava kirliligi, insan ve diger canlilara zarar verecek miktarda kirleticilerin dogal aktiviteler veya insan aktiviteleri sonucu atmosfere karismasi seklinde tanimlanabilir. Dunyada her yil tahminen 3 milyondan fazla kisi hava kirliligi nedeniyle olmektedir.Bu calisma,bir universitede yapilan bahar senliklerine katilanlarin hava kalitesi hakkindaki bilgi duzeyini degerlendirmek, yasadiklari ilin hava kalitesinitakip edip etmediklerini belirlemek amaciyla yapilmistir. Gerec ve Yontem: Bu tanimlayici arastirma bir universitede duzenlenen bahar senliklerine katilanlardan rastgele secilen 200 kisi uzerinde 8-9 Mayis 2014 tarihlerinde yapildi. Hava kalitesi konusundaki bilgi duzeyini belirlemeye yonelik 15 soruluk anket uygulandi ve katilimcilara hava kalitesi ile ilgili bilgilendirme formu verildi. Bir sayfalik bilgilendirme formunda hava kirliligi tanimi, onemi, Partikul Madde'nin saglik uzeri...

Research paper thumbnail of Suicide attempts and related factors in schizophrenia patients

Objectives: To investigate the relationship between suicide attempts and demographic-clinical var... more Objectives: To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts. Methods: A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the Department of Psychiatry, Selcuk University and the Beyhekim Psychiatric Clinic Konya Training and Research Hospital, Konya, Turkey, between January 2014 and January 2018 The data collection forms created by researchers were completed using hospital medical records. Results: It was determined that 40.8% of schizophrenia patients attempted suicide at least once and that 39.6% of schizophrenia patients who attempted suicide had recurrent suicide attempts. Those with suicide attempts had a significantly longer mean duration of untreated psychosis and a higher total number of hospitalizations compared to those without suicide attempts. In addition, t...

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Lityum, 1800’lu yillarin basinda Isvecli Arfvedson tarafindan kesfedilmis ve 1950’li yillarda psi... more Lityum, 1800’lu yillarin basinda Isvecli Arfvedson tarafindan kesfedilmis ve 1950’li yillarda psikiyatri alaninda kullanilmaya baslanmistir. Yetiskinlerde bipolar tedavisinde ilk sirada gelen bir duygudurum duzenleyici ve altin standart bir tedavi ajanidir. Ancak, klinik uygulamada bireyler arasinda lityum tedavisine yanit oranlari hastalarin farkli ozellikleri nedeniyle oldukca degisken olup, hangi hastanin lityuma iyi yanit verecegini ongormek cogunlukla zordur. Lityum tedavi yanitini ongormede klinisyenler oncelikle klinik bir fenotipi tanimaya odaklanmis gibi durmaktadir. Bu yazida lityum tedavi yanitinin yordayicilari ile ilgili arastirmalar gozden gecirilerek; klinik, biyokimyasal, norogoruntuleme ve genetik yordayicilar olmak uzere dort baslik altinda ele alinmistir.

Research paper thumbnail of Clinical, Biological and Genetic Predictors of Lithium Treatment Response

Lithium was discovered by the Swedish Arfvedson at the beginning of the 1800s and began to be use... more Lithium was discovered by the Swedish Arfvedson at the beginning of the 1800s and began to be used in psychiatry for the past 1950s. Lithium, as a mood stabilizer, is the gold standard and first choice treatment agent for the treatment of bipolar disorders in adults. However, it is mostly difficult in clinical practice to predict which patient would respond to the treatment with lithium well due to the huge variation in patients’ characteristics. Clinicians seem to focus primarily on identifying a clinical phenotype to foresee lithium treatment response. In this article, researches on predictors of the lithium treatment response were reviewed and evaluated in four titles as clinical, biochemical, neuroimaging and genetic predictors.

Research paper thumbnail of Predictors of discontinuation and hospitalization during long-acting injectable antipsychotic treatment in patients with schizophrenia spectrum disorder

International Clinical Psychopharmacology

Research paper thumbnail of Suicide attempts and related factors in schizophrenia patients

Saudi Medical Journal

Objectives: To investigate the relationship between suicide attempts and demographic-clinical var... more Objectives: To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts. Methods: A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the

Research paper thumbnail of Evaluation of the recurrence rates after the first manic episode: one year follow-up study

European Neuropsychopharmacology

Research paper thumbnail of Oral Research Presentations

Psychiatry and Clinical Psychopharmacology

Objective: Many individuals with cigarette addiction are known for beginning to smoke cigarettes ... more Objective: Many individuals with cigarette addiction are known for beginning to smoke cigarettes during adolescence years. In this study, we aimed to present the clinical outcomes of smoking cessation project conducted in an Anatolian school in Kartal district of Istanbul, Turkey. Methods: Social and motivational studies were carried out on adolescent smokers after scanning in terms of smoking in an Anatolian school and 44 of these adolescents who are clinical requirements were evaluated and followed by Chest disease and child and adolescent mental health for six months. Carbonmonoxide (CO) measurements in the expiratory air and carboximeter (piCO smokerlyzer, Bedfont Scientific Ltd, England) were made at the first visit and follow-up. Simultaneously, K-SADS PL (Schedule for Schizophrenia and Affective disorders for School Age Children) was administered diagnostically in mental health evaluation. Results: A total of 44 adolescents, 13 girl (29.5%) and 31 boy (70.5%), with a mean age of 17.31 were followed up. The mean age of initiation of cigarette smoking was 14.2 ± 1 and 32 (82.7%) adolescent were found to have at least one smoker in their home. While 22.7% of adolescents did not try smoking cessation, 77.3% of them did. Six of these adolescents indicated that they did not smoke during the six months; 55.5% of these adolescents have at least one mental illness; the most common diagnoses were 25.0% (n = 11) of ADHD (Attention Deficit Hyperactivity Disorder) and 20% (10) of MD (Major Depression). While depression was significantly frequent in girls (p = 0.043), the frequency of ADHD was not significant in terms of gender. Depression presence was associated with early onset of cigarette smoking in males (p = 0.019), but not with females (p = 0.394). There was a statistically significant correlation between smoking cessation effort and age in the follow-up period (p = 0.022), and earlier adolescents stated that they wanted to quit smoking more. While there is no significant association between smoking cessation effort and mental disease, there was a statistically close relation with parent and sibling smoking (p = 0.07) and significant correlation with motivation and smoking cessation effort (p = 0.016). Conclusions: Smoking cessation work in adolescents is much more difficult than in adults. Biological and social factors and peer impact influence interventions. In our study, very few adolescents stated to quit smoking for 6 months, and the rate of psychiatric illnesses among adolescents and the presence of individuals smoking at home were found to be quite high. It has been the result of these factors also affecting the success of adolescents to start smoking and to quit smoking.

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry

Research paper thumbnail of Evaluation of the relationship between suicidal behavior and the sirt1 gene in patients with schizophrenia

Research paper thumbnail of P.0416 Modafinil increases the number of hypomanic symptoms in patients with bipolar depressive symptoms?

European Neuropsychopharmacology, 2021

Research paper thumbnail of P.613 Comparison of clinical and biochemical features between bipolar patients on mood stabilizer alone or combination treatment

European Neuropsychopharmacology, 2019

Research paper thumbnail of P.0076 Evaluation of the staging after the first manic episode in patients with bipolar disorder

European Neuropsychopharmacology, 2021

Research paper thumbnail of Bi̇r Üni̇versi̇te Bahar Şenli̇kleri̇ne Katilanlarin Hava Ki̇rli̇li̇ği̇ Bi̇lgi̇ Düzeyi̇ni̇n Araştirilmasi

Giris ve Amac: Toplum sagligini tehdit eden sorunlarin basinda hava kirliligi gelmektedir. Hava k... more Giris ve Amac: Toplum sagligini tehdit eden sorunlarin basinda hava kirliligi gelmektedir. Hava kirliligi, insan ve diger canlilara zarar verecek miktarda kirleticilerin dogal aktiviteler veya insan aktiviteleri sonucu atmosfere karismasi seklinde tanimlanabilir. Dunyada her yil tahminen 3 milyondan fazla kisi hava kirliligi nedeniyle olmektedir.Bu calisma,bir universitede yapilan bahar senliklerine katilanlarin hava kalitesi hakkindaki bilgi duzeyini degerlendirmek, yasadiklari ilin hava kalitesinitakip edip etmediklerini belirlemek amaciyla yapilmistir. Gerec ve Yontem: Bu tanimlayici arastirma bir universitede duzenlenen bahar senliklerine katilanlardan rastgele secilen 200 kisi uzerinde 8-9 Mayis 2014 tarihlerinde yapildi. Hava kalitesi konusundaki bilgi duzeyini belirlemeye yonelik 15 soruluk anket uygulandi ve katilimcilara hava kalitesi ile ilgili bilgilendirme formu verildi. Bir sayfalik bilgilendirme formunda hava kirliligi tanimi, onemi, Partikul Madde'nin saglik uzeri...

Research paper thumbnail of Suicide attempts and related factors in schizophrenia patients

Objectives: To investigate the relationship between suicide attempts and demographic-clinical var... more Objectives: To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts. Methods: A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the Department of Psychiatry, Selcuk University and the Beyhekim Psychiatric Clinic Konya Training and Research Hospital, Konya, Turkey, between January 2014 and January 2018 The data collection forms created by researchers were completed using hospital medical records. Results: It was determined that 40.8% of schizophrenia patients attempted suicide at least once and that 39.6% of schizophrenia patients who attempted suicide had recurrent suicide attempts. Those with suicide attempts had a significantly longer mean duration of untreated psychosis and a higher total number of hospitalizations compared to those without suicide attempts. In addition, t...

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Lityum, 1800’lu yillarin basinda Isvecli Arfvedson tarafindan kesfedilmis ve 1950’li yillarda psi... more Lityum, 1800’lu yillarin basinda Isvecli Arfvedson tarafindan kesfedilmis ve 1950’li yillarda psikiyatri alaninda kullanilmaya baslanmistir. Yetiskinlerde bipolar tedavisinde ilk sirada gelen bir duygudurum duzenleyici ve altin standart bir tedavi ajanidir. Ancak, klinik uygulamada bireyler arasinda lityum tedavisine yanit oranlari hastalarin farkli ozellikleri nedeniyle oldukca degisken olup, hangi hastanin lityuma iyi yanit verecegini ongormek cogunlukla zordur. Lityum tedavi yanitini ongormede klinisyenler oncelikle klinik bir fenotipi tanimaya odaklanmis gibi durmaktadir. Bu yazida lityum tedavi yanitinin yordayicilari ile ilgili arastirmalar gozden gecirilerek; klinik, biyokimyasal, norogoruntuleme ve genetik yordayicilar olmak uzere dort baslik altinda ele alinmistir.

Research paper thumbnail of Clinical, Biological and Genetic Predictors of Lithium Treatment Response

Lithium was discovered by the Swedish Arfvedson at the beginning of the 1800s and began to be use... more Lithium was discovered by the Swedish Arfvedson at the beginning of the 1800s and began to be used in psychiatry for the past 1950s. Lithium, as a mood stabilizer, is the gold standard and first choice treatment agent for the treatment of bipolar disorders in adults. However, it is mostly difficult in clinical practice to predict which patient would respond to the treatment with lithium well due to the huge variation in patients’ characteristics. Clinicians seem to focus primarily on identifying a clinical phenotype to foresee lithium treatment response. In this article, researches on predictors of the lithium treatment response were reviewed and evaluated in four titles as clinical, biochemical, neuroimaging and genetic predictors.

Research paper thumbnail of Predictors of discontinuation and hospitalization during long-acting injectable antipsychotic treatment in patients with schizophrenia spectrum disorder

International Clinical Psychopharmacology

Research paper thumbnail of Suicide attempts and related factors in schizophrenia patients

Saudi Medical Journal

Objectives: To investigate the relationship between suicide attempts and demographic-clinical var... more Objectives: To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts. Methods: A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the

Research paper thumbnail of Evaluation of the recurrence rates after the first manic episode: one year follow-up study

European Neuropsychopharmacology

Research paper thumbnail of Oral Research Presentations

Psychiatry and Clinical Psychopharmacology

Objective: Many individuals with cigarette addiction are known for beginning to smoke cigarettes ... more Objective: Many individuals with cigarette addiction are known for beginning to smoke cigarettes during adolescence years. In this study, we aimed to present the clinical outcomes of smoking cessation project conducted in an Anatolian school in Kartal district of Istanbul, Turkey. Methods: Social and motivational studies were carried out on adolescent smokers after scanning in terms of smoking in an Anatolian school and 44 of these adolescents who are clinical requirements were evaluated and followed by Chest disease and child and adolescent mental health for six months. Carbonmonoxide (CO) measurements in the expiratory air and carboximeter (piCO smokerlyzer, Bedfont Scientific Ltd, England) were made at the first visit and follow-up. Simultaneously, K-SADS PL (Schedule for Schizophrenia and Affective disorders for School Age Children) was administered diagnostically in mental health evaluation. Results: A total of 44 adolescents, 13 girl (29.5%) and 31 boy (70.5%), with a mean age of 17.31 were followed up. The mean age of initiation of cigarette smoking was 14.2 ± 1 and 32 (82.7%) adolescent were found to have at least one smoker in their home. While 22.7% of adolescents did not try smoking cessation, 77.3% of them did. Six of these adolescents indicated that they did not smoke during the six months; 55.5% of these adolescents have at least one mental illness; the most common diagnoses were 25.0% (n = 11) of ADHD (Attention Deficit Hyperactivity Disorder) and 20% (10) of MD (Major Depression). While depression was significantly frequent in girls (p = 0.043), the frequency of ADHD was not significant in terms of gender. Depression presence was associated with early onset of cigarette smoking in males (p = 0.019), but not with females (p = 0.394). There was a statistically significant correlation between smoking cessation effort and age in the follow-up period (p = 0.022), and earlier adolescents stated that they wanted to quit smoking more. While there is no significant association between smoking cessation effort and mental disease, there was a statistically close relation with parent and sibling smoking (p = 0.07) and significant correlation with motivation and smoking cessation effort (p = 0.016). Conclusions: Smoking cessation work in adolescents is much more difficult than in adults. Biological and social factors and peer impact influence interventions. In our study, very few adolescents stated to quit smoking for 6 months, and the rate of psychiatric illnesses among adolescents and the presence of individuals smoking at home were found to be quite high. It has been the result of these factors also affecting the success of adolescents to start smoking and to quit smoking.

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry

Research paper thumbnail of Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik Yordayıcıları

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry