Venkateshwarlu Gaddam - Academia.edu (original) (raw)
Papers by Venkateshwarlu Gaddam
Panchakarma (Five fold therapeutic methods of Ayurveda) has immense potential in the context of t... more Panchakarma (Five fold therapeutic methods of Ayurveda) has immense potential in the context of tackling the lifestyle disorders with special reference to Madhumeha (Diabetes Mellitus). Ayurvedic Panchakarma procedures have been becoming popular of late and its usefulness in prevention and management of lifestyle disorders especially the Madhumeha may be one of the reason. It is therefore essential to recognize the potential of Panchakarma therapy of Ayurveda and convert into mainstream treatment. As a prelude to this, an attempt has been made to present the Ayurvedic textual references describing the multidimensional utility of Panchakarma especially the shodhana (Purificatory therapeutic methods of Ayurveda) in the prevention and management of Madhumeha. Efforts have been also made to hypothesize the mode of action of this therapeutic plan. It is proposed that prior to pharmacological intervention i.e., either Ayurveda or modern anti-diabetic management, shodhana might be extremel...
Journal of Drug Research in Ayurvedic Sciences, 2017
The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the f... more The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the family Musaceae, is used as pathya in atisara (diarrhea), in grahani (irritable bowel syndrome), and agnimandya (loss of appetite). The unripe fruits are considered to be helpful in the management of diabetes mellitus. Being an important medicinal plant, the present investigation is an attempt to explore the pharmacognostical analysis and thin-layer chromatography fingerprint studies on the widely used Musa. × paradisiaca L. The studies revealed that unripe banana fruit showed the presence of small outer protrusion of papillae on the epidermis, abundant tannin-containing cells in the epicarp and mesocarp. Elongated air-spaced cells are surrounded by the parenchyma cells in the epicarp, abundant starch grains in the mesocarp portion, and acicular crystals of calcium oxalate in raphide bundles. To detect the location of various constituents of the drug, sections of unripe fruits were treate...
Pharmacognosy Journal, 2016
Pharmacognosy Journal, 2015
European Journal of Herbal Medicine
The Present communication deals with the various pharmacognostic evaluation on the leaves of Xime... more The Present communication deals with the various pharmacognostic evaluation on the leaves of Ximenia americana include morphological, microscopical characters, powder microscopy and physicochemical characters like ash values and loss on drying, TLC studies etc.The preliminary phytochemical screening is also carried out and it is revealed that, the presence of Alkaloids, Sterpoids, Sugars, Saponins,Tannins, and Terpenoides in methanol extract. Steroids in traces and absence of Terpenoides in ethanol and aqueous extract of the leaves of X.americana which may be responsible for its antinociceptive activity. INTRODUCTION Ximenia americana Linn is a small tree or shrub native to African tropics but can also be found in many parts of the world belongs to family Olacaceae 1 . It is commonly known as false sandal wood, Wild Plum, tallow wood, Sour Plum, Yellow Plum or Sea Lemon. It is a large straggling, variable shrub or a small tree, reaching height up to 4.5 meters with spiny branches, s...
Asian Journal of Plant Sciences, 2011
Journal of Complementary Medicine & Alternative Healthcare, 2019
Journal of Drug Research in Ayurvedic Sciences, Mar 1, 2017
The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the f... more The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the family Musaceae, is used as pathya in atisara (diarrhea), in grahani (irritable bowel syndrome), and agnimandya (loss of appetite). The unripe fruits are considered to be helpful in the management of diabetes mellitus. Being an important medicinal plant, the present investigation is an attempt to explore the pharmacognostical analysis and thin-layer chromatography fingerprint studies on the widely used Musa. × paradisiaca L. The studies revealed that unripe banana fruit showed the presence of small outer protrusion of papillae on the epidermis, abundant tannin-containing cells in the epicarp and mesocarp. Elongated air-spaced cells are surrounded by the parenchyma cells in the epicarp, abundant starch grains in the mesocarp portion, and acicular crystals of calcium oxalate in raphide bundles. To detect the location of various constituents of the drug, sections of unripe fruits were treated with various reagents, and studies showed the presence of phenols, protein, calcium oxalate, magnesium, starch, cellulose, calcium pectate, lignin, sulfated mucopolysaccharides, tannin, and silica contents. Phytochemical studies showed the presence of alkaloids, carbohydrates, phenols, proteins, starch, tannins, steroids, and saponins.
Journal of Research and Education in Indian Medicine (Estt.1982), 2017
ABSTRACT Objective: The primary aim of the study was to establish the pharmacognostic standards a... more ABSTRACT
Objective: The primary aim of the study was to establish the
pharmacognostic
standards along with nutritional values on the important
medicinal herb Glinus oppositifolius (L.) Aug. DC., commonly known
as Parpata in South India. Material and Methods: Pharmacognostical,
physicochemical, nutritional evaluation along with the TLC profiling and
preliminary phytochemical screening was carried out. Results: Histological
study of different parts of the plant revealed the presence of different
cellular structures viz. stem showed the presence of multi cellular
to unicellular trichomes, collateral vascular bundles, starch grains etc.
Mesophyll of the leaves was embedded with starch grains with clustered
calcium oxalate and prism shaped crystals. Anomocytic stomata
were present on both the epidermis of the leaf. Powder microscopy
exhibited multi cellular trichomes, clustered calcium oxalate, fibres etc.
Physicochemical and histochemical studies revealed the presence of
various secondary metabolites and different minerals within the acceptable
limits. Thin layer chromatographic profiling showed different spots
suggesting the presence of specific phytoconstituents in different extracts.
The plant also revealed good nutritional value with calorific value
of about 245 kcal/100g; Vitamin C 112 mg/100 g and higher amount of
calcium etc. Conclusion: The results are beneficial to establish the quality
control parameters of the plant species and may be served as future
reference for the identification and authentication of the genuine crude
drug and also provide sufficient data to recognize the use of the plant as
dietary suppliment.
Key words: Antidiabetic, Pharmacognosy, Standardization, Thin layer
chromatography,
Powder microscopy, Histochemical studies.
Address for Correspondence:
Dr. Shantha Thirumalai Ramaseshan, Drug Standardization Research
Unit, Research Officer (Botany), National Ayurveda Dietetics Research
Institute, (CCRAS, Ministry
of AYUSH, Govt. of India), Bangalore-560011,
India.
Phone no: 91- 9986365762, Telephone (O): 91-080-26562030
E-mail: shanthatr57@gmail.com
DOI : 10.5530/pj.2016.1.7
The Present communication deals with the various pharmacognostic evaluation on the leaves of Xime... more The Present communication deals with the various pharmacognostic evaluation on the leaves of Ximenia americana include morphological, microscopical characters, powder microscopy and physicochemical characters like ash values and loss on drying, TLC studies etc.The preliminary phytochemical screening is also carried out and it is revealed that, the presence of Alkaloids, Sterpoids, Sugars, Saponins,Tannins, and Terpenoides in methanol extract. Steroids in traces and absence of Terpenoides in ethanol and aqueous extract of the leaves of X.americana which may be responsible for its antinociceptive activity.
![Research paper thumbnail of Traditional & Ayurvedic Medicinal Importance of Agastya Leaves [Sesbania grandiflora (L) Pers.] W.R.T. its Pharmacognostic and Physicochemical evaluation. International Journal of Research in Ayurveda & Pharmacy, 3(2) 2012.](https://attachments.academia-assets.com/38554125/thumbnails/1.jpg)
](Agasthya [Sesbania grandiflora (L) Pers.] a traditionally revered Ayurvedic medicinal plant espec... more Agasthya [Sesbania grandiflora (L) Pers.] a traditionally revered Ayurvedic medicinal plant especially in Southern India. It goes as a principal ingredient in preparation of Ayurvedic medicinal formulations. Classical texts of Ayurveda have attributed wide ranging therapeutic indications to the herb. Agasthya leaves are known to possess anthehelmintic, alixeteric properties aperient, tonic, diuretic, and laxative properties. Further, they have been documented as therapeutically useful in Kaphaja disorders, pruritis, skin disorders, night blindness, epilepsy, gout, ophthalmia nasal catarrh and headache. The leaves contain a non-poisonous saponin. The present study is an attempt to decipher the rationality of the traditional use of leaves with an Ayurvedic perspective vis-à-vis pharmacognostical and physicochemical evaluation of the plant.
Abstract: An attempt has been made to present the therapeutic uses of flowers that are used in Ay... more Abstract: An attempt has been made to present the therapeutic uses of flowers that are used
in Ayurveda and Siddha system of Medicine. Separate chapters have been dedicated to
flowers in the ancient texts like Bhavaprakasha Nighantu . Likewise Siddha Vaidya has described
the therapeutic utility of medicinal flowers. It is interesting to note that out of 38 medicinal flowers
tabulated, about 25 flowers have some similar indications in Ayurveda and Siddha system of
medicine. In some instances, the properties of the flower may differ from the properties of other parts
of the plant, for example, Arka{Calotropis gigantea (Linn.) R. Br.} Pushpa (flower) is madhura
(sweet in taste) tikta (bitter) and is used as Kustagna, Krimigna (anthelmintic) whereas Arka
ksheera (latex) is tikta (Bitter) and hot in potency. Similarly, Nirgundi (Vitex negundo Linn.) is a tree,
whose other parts have ushna veerya (hot in potency). However, the pushpa is sheeta veerya (cold
potency). Some special properties have been attributed to certain flowers like anti cancerous property
is possessed by Vinca rosea(Sadapushpi) flower. Punica granatum L. (Dadima), flower has styptic
properties, hence used in the form of juice for epistaxis (condition characterized by bleeding through
the nostrils (Rakta pitta), similarly Justicia adhatoda L.(Vasa) flowers have Kashaya (astringent)
Kasahara (antitussive) properties. The most popular flower buds of Lavanga { Syzgium aromaticum
(L.) Merr. & Perry} (forms the clove, which has been used as a spice as well the clove oil being used
in dental problems. The most popular narcotic “Papaverine” is obtained from the flowers of Ahiphena
(Papaver somniferum L.) Thus, flowers have got a distinct place in the plant kingdom as well in
the field of Ayurveda and Siddha system of Medicine. Thus, the present review of medicinal flowers
not only provides recognition to this knowledge, but also helps in its conservation vis-a-vis
providing pharmacological leads for the betterment of human society.
Keywords: Ayurveda, Medicinal Flowers, Therapeutic utility, Ayurveda, Siddha, Review, Traditional
Medicine.
Panchakarma (Five fold therapeutic methods of Ayurveda) has immense potential in the context of t... more Panchakarma (Five fold therapeutic methods of Ayurveda) has immense potential in the context of tackling the lifestyle disorders with special reference to Madhumeha (Diabetes Mellitus). Ayurvedic Panchakarma procedures have been becoming popular of late and its usefulness in prevention and management of lifestyle disorders especially the Madhumeha may be one of the reason. It is therefore essential to recognize the potential of Panchakarma therapy of Ayurveda and convert into mainstream treatment. As a prelude to this, an attempt has been made to present the Ayurvedic textual references describing the multidimensional utility of Panchakarma especially the shodhana (Purificatory therapeutic methods of Ayurveda) in the prevention and management of Madhumeha. Efforts have been also made to hypothesize the mode of action of this therapeutic plan. It is proposed that prior to pharmacological intervention i.e., either Ayurveda or modern anti-diabetic management, shodhana might be extremel...
Journal of Drug Research in Ayurvedic Sciences, 2017
The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the f... more The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the family Musaceae, is used as pathya in atisara (diarrhea), in grahani (irritable bowel syndrome), and agnimandya (loss of appetite). The unripe fruits are considered to be helpful in the management of diabetes mellitus. Being an important medicinal plant, the present investigation is an attempt to explore the pharmacognostical analysis and thin-layer chromatography fingerprint studies on the widely used Musa. × paradisiaca L. The studies revealed that unripe banana fruit showed the presence of small outer protrusion of papillae on the epidermis, abundant tannin-containing cells in the epicarp and mesocarp. Elongated air-spaced cells are surrounded by the parenchyma cells in the epicarp, abundant starch grains in the mesocarp portion, and acicular crystals of calcium oxalate in raphide bundles. To detect the location of various constituents of the drug, sections of unripe fruits were treate...
Pharmacognosy Journal, 2016
Pharmacognosy Journal, 2015
European Journal of Herbal Medicine
The Present communication deals with the various pharmacognostic evaluation on the leaves of Xime... more The Present communication deals with the various pharmacognostic evaluation on the leaves of Ximenia americana include morphological, microscopical characters, powder microscopy and physicochemical characters like ash values and loss on drying, TLC studies etc.The preliminary phytochemical screening is also carried out and it is revealed that, the presence of Alkaloids, Sterpoids, Sugars, Saponins,Tannins, and Terpenoides in methanol extract. Steroids in traces and absence of Terpenoides in ethanol and aqueous extract of the leaves of X.americana which may be responsible for its antinociceptive activity. INTRODUCTION Ximenia americana Linn is a small tree or shrub native to African tropics but can also be found in many parts of the world belongs to family Olacaceae 1 . It is commonly known as false sandal wood, Wild Plum, tallow wood, Sour Plum, Yellow Plum or Sea Lemon. It is a large straggling, variable shrub or a small tree, reaching height up to 4.5 meters with spiny branches, s...
Asian Journal of Plant Sciences, 2011
Journal of Complementary Medicine & Alternative Healthcare, 2019
Journal of Drug Research in Ayurvedic Sciences, Mar 1, 2017
The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the f... more The unripe fruit of Musa × paradisiaca L., classically known as apakva kadali, belonging to the family Musaceae, is used as pathya in atisara (diarrhea), in grahani (irritable bowel syndrome), and agnimandya (loss of appetite). The unripe fruits are considered to be helpful in the management of diabetes mellitus. Being an important medicinal plant, the present investigation is an attempt to explore the pharmacognostical analysis and thin-layer chromatography fingerprint studies on the widely used Musa. × paradisiaca L. The studies revealed that unripe banana fruit showed the presence of small outer protrusion of papillae on the epidermis, abundant tannin-containing cells in the epicarp and mesocarp. Elongated air-spaced cells are surrounded by the parenchyma cells in the epicarp, abundant starch grains in the mesocarp portion, and acicular crystals of calcium oxalate in raphide bundles. To detect the location of various constituents of the drug, sections of unripe fruits were treated with various reagents, and studies showed the presence of phenols, protein, calcium oxalate, magnesium, starch, cellulose, calcium pectate, lignin, sulfated mucopolysaccharides, tannin, and silica contents. Phytochemical studies showed the presence of alkaloids, carbohydrates, phenols, proteins, starch, tannins, steroids, and saponins.
Journal of Research and Education in Indian Medicine (Estt.1982), 2017
ABSTRACT Objective: The primary aim of the study was to establish the pharmacognostic standards a... more ABSTRACT
Objective: The primary aim of the study was to establish the
pharmacognostic
standards along with nutritional values on the important
medicinal herb Glinus oppositifolius (L.) Aug. DC., commonly known
as Parpata in South India. Material and Methods: Pharmacognostical,
physicochemical, nutritional evaluation along with the TLC profiling and
preliminary phytochemical screening was carried out. Results: Histological
study of different parts of the plant revealed the presence of different
cellular structures viz. stem showed the presence of multi cellular
to unicellular trichomes, collateral vascular bundles, starch grains etc.
Mesophyll of the leaves was embedded with starch grains with clustered
calcium oxalate and prism shaped crystals. Anomocytic stomata
were present on both the epidermis of the leaf. Powder microscopy
exhibited multi cellular trichomes, clustered calcium oxalate, fibres etc.
Physicochemical and histochemical studies revealed the presence of
various secondary metabolites and different minerals within the acceptable
limits. Thin layer chromatographic profiling showed different spots
suggesting the presence of specific phytoconstituents in different extracts.
The plant also revealed good nutritional value with calorific value
of about 245 kcal/100g; Vitamin C 112 mg/100 g and higher amount of
calcium etc. Conclusion: The results are beneficial to establish the quality
control parameters of the plant species and may be served as future
reference for the identification and authentication of the genuine crude
drug and also provide sufficient data to recognize the use of the plant as
dietary suppliment.
Key words: Antidiabetic, Pharmacognosy, Standardization, Thin layer
chromatography,
Powder microscopy, Histochemical studies.
Address for Correspondence:
Dr. Shantha Thirumalai Ramaseshan, Drug Standardization Research
Unit, Research Officer (Botany), National Ayurveda Dietetics Research
Institute, (CCRAS, Ministry
of AYUSH, Govt. of India), Bangalore-560011,
India.
Phone no: 91- 9986365762, Telephone (O): 91-080-26562030
E-mail: shanthatr57@gmail.com
DOI : 10.5530/pj.2016.1.7
The Present communication deals with the various pharmacognostic evaluation on the leaves of Xime... more The Present communication deals with the various pharmacognostic evaluation on the leaves of Ximenia americana include morphological, microscopical characters, powder microscopy and physicochemical characters like ash values and loss on drying, TLC studies etc.The preliminary phytochemical screening is also carried out and it is revealed that, the presence of Alkaloids, Sterpoids, Sugars, Saponins,Tannins, and Terpenoides in methanol extract. Steroids in traces and absence of Terpenoides in ethanol and aqueous extract of the leaves of X.americana which may be responsible for its antinociceptive activity.
Agasthya [Sesbania grandiflora (L) Pers.] a traditionally revered Ayurvedic medicinal plant espec... more Agasthya [Sesbania grandiflora (L) Pers.] a traditionally revered Ayurvedic medicinal plant especially in Southern India. It goes as a principal ingredient in preparation of Ayurvedic medicinal formulations. Classical texts of Ayurveda have attributed wide ranging therapeutic indications to the herb. Agasthya leaves are known to possess anthehelmintic, alixeteric properties aperient, tonic, diuretic, and laxative properties. Further, they have been documented as therapeutically useful in Kaphaja disorders, pruritis, skin disorders, night blindness, epilepsy, gout, ophthalmia nasal catarrh and headache. The leaves contain a non-poisonous saponin. The present study is an attempt to decipher the rationality of the traditional use of leaves with an Ayurvedic perspective vis-à-vis pharmacognostical and physicochemical evaluation of the plant.
Abstract: An attempt has been made to present the therapeutic uses of flowers that are used in Ay... more Abstract: An attempt has been made to present the therapeutic uses of flowers that are used
in Ayurveda and Siddha system of Medicine. Separate chapters have been dedicated to
flowers in the ancient texts like Bhavaprakasha Nighantu . Likewise Siddha Vaidya has described
the therapeutic utility of medicinal flowers. It is interesting to note that out of 38 medicinal flowers
tabulated, about 25 flowers have some similar indications in Ayurveda and Siddha system of
medicine. In some instances, the properties of the flower may differ from the properties of other parts
of the plant, for example, Arka{Calotropis gigantea (Linn.) R. Br.} Pushpa (flower) is madhura
(sweet in taste) tikta (bitter) and is used as Kustagna, Krimigna (anthelmintic) whereas Arka
ksheera (latex) is tikta (Bitter) and hot in potency. Similarly, Nirgundi (Vitex negundo Linn.) is a tree,
whose other parts have ushna veerya (hot in potency). However, the pushpa is sheeta veerya (cold
potency). Some special properties have been attributed to certain flowers like anti cancerous property
is possessed by Vinca rosea(Sadapushpi) flower. Punica granatum L. (Dadima), flower has styptic
properties, hence used in the form of juice for epistaxis (condition characterized by bleeding through
the nostrils (Rakta pitta), similarly Justicia adhatoda L.(Vasa) flowers have Kashaya (astringent)
Kasahara (antitussive) properties. The most popular flower buds of Lavanga { Syzgium aromaticum
(L.) Merr. & Perry} (forms the clove, which has been used as a spice as well the clove oil being used
in dental problems. The most popular narcotic “Papaverine” is obtained from the flowers of Ahiphena
(Papaver somniferum L.) Thus, flowers have got a distinct place in the plant kingdom as well in
the field of Ayurveda and Siddha system of Medicine. Thus, the present review of medicinal flowers
not only provides recognition to this knowledge, but also helps in its conservation vis-a-vis
providing pharmacological leads for the betterment of human society.
Keywords: Ayurveda, Medicinal Flowers, Therapeutic utility, Ayurveda, Siddha, Review, Traditional
Medicine.