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Papers by Deepali Vidhate

Journal of Mobile Multimedia

Objectives: A kind of Artificial Neural Network (ANN) known as a Back Propagation Neural Network ... more Objectives: A kind of Artificial Neural Network (ANN) known as a Back Propagation Neural Network (BPNN) has been extensively applied in a variety of sectors, including medical diagnosis, optical character recognition, stock market forecasting, and others. Many studies have employed BPNN to create decision-support tools for doctors to use while making clinical diagnoses. Chronic Kidney Disease (CKD) is one such kind of disease which has been receiving due importance from the past decades due to lack of symptoms in its early stages. The goal of this work is to demonstrate the performance of Artificial Intelligent (AI) algorithms in the early detection of CKD. Method: We received 800 patients’ real-time data from DY Patil Hospitals for this investigation. Self-Acclimation Graded Boolean PSO (SAG-BPSO), a modified version of Particle Swarm Optimization (PSO), has been proposed and used in this study to accomplish feature selection. Cuckoo Search Algorithm (CSA) has been used to optimise...

International Journal of System Assurance Engineering and Management

Medpulse International Journal of General Medicine, 2019

MedPulse International Journal of Medicine, 2019

Introduction: Coronary artery disease (CAD) is a leading cause of mortality worldwide. In develop... more Introduction: Coronary artery disease (CAD) is a leading cause of mortality worldwide. In developing countries it has been observed that stressful life style is mainly associated with CAD. Inflammatory environment has been produced due to formation of various oxidant a present study aimed to compare the circulatory levels of homocysteine in CAD patients and normal controls. Methodology: The study protocol was approved by institutional ethical patients and 91 age sex matched controls) have been included in the present study. Blood sugar, lipid profile levels were estimated in both CAD patients and controls. [17.41± (10.27)] compared to the controls [7.38± (3.67)]. No significant difference have been observed in LDL levels in controls and CAD respectively [105.32(±33.66)/ 108.93(±41.51)]. However HDL levels were found to be significantly lower in CAD patients than controls [ and Hypertension (HTN) in CAD group has shown high homocysteine than CAD patients without any additional risk f...

International Journal of Health Sciences (IJHS), Aug 25, 2022

Inflammation is known to be the root cause of the development of coronary artery disease (CAD). S... more Inflammation is known to be the root cause of the development of coronary artery disease (CAD). Subclinical inflammation is one of the key players in pathophysiology of CAD. An

Asian Pacific Journal of Health Sciences

Genetic research has brought a lot of new knowledge in the area of genetic predisposition of type... more Genetic research has brought a lot of new knowledge in the area of genetic predisposition of type 2 diabetes mellitus (T2DM). It has been proposed that excessive insulin resistance and obesity are also responsible for the higher incidence of type 2 diabetes. Calpain-10 (CAPN10) is a member of a large family of intracellular proteases. The polymorphism at deletion/insertion SNP19 of this gene influences susceptibility to T2DM. The aim of the study was to determine whether calpain-10 (ins/del SNP19) polymorphism contributes significantly to susceptibility to T2DM in population of Navi Mumbai. The study included randomly selected 75 patients of which 33 had T2DM and 42 served as control subjects. Mean waist-to-hip ratio, HDL, LDL, VLDL, cholesterol, and triglyceride showed no difference whereas mean of age, FBS, and body mass index showed significant differences between the control and diabetes subjects. Genotyping of calpain-10 (ins/del SNP19) polymorphism was performed by polymerase ...

Professor, Department of Biochemistry, D Y Patil Deemed to be University School of Medicine, Neru... more Professor, Department of Biochemistry, D Y Patil Deemed to be University School of Medicine, Nerul, Navi Mumbai, India. Ph.D. Scholar Department of Biochemistry, D Y Patil Deemed to be University School of Medicine, Nerul, Navi Mumbai, India. MBBS Students D Y Patil Deemed to be University School of Medicine, Nerul, Navi Mumbai, India. Professor and Head of the Department of Cardiovascular and Thoracic surgery, D Y Patil Deemed to be University School of Medicine and Hospital, Nerul, Navi Mumbai, India. Professor, Department of Computer Science, RAIT, D Y Patil Deemed to be University School of Engineering, Nerul, Navi Mumbai, India.

2021 2nd International Conference on Smart Electronics and Communication (ICOSEC), 2021

Chronic Kidney Disease (CKD) is a global health threat that affects approximately 10% of the glob... more Chronic Kidney Disease (CKD) is a global health threat that affects approximately 10% of the global population and approximately 20% of the Indian population. Medical specialists face a large and difficult burden in detecting this disease at an early stage. In this case, a computer-based intelligent system that can diagnose kidney disease and its stages could be unbelievably valuable. Artificial Intelligence (AI) is being used by researchers and scientists to create smart solutions. This paper gives a gist of the different varieties of works done by different scholars in the field of early prediction of CKD using AI techniques. Further, all the works are categorized into 3 different categories and further it has been attempted to analyze the best proposals in those categories. Finally, it has been concluded with the most optimizing and exhaustive proposal.

Diabetes has already reached an epidemic level in India. Chronic inflammation has been considered... more Diabetes has already reached an epidemic level in India. Chronic inflammation has been considered as a culprit for setting pathophysiological changes which results in insulin resistance and type 2 diabetes mellitus. IL-6 is one of the several proinflammatory cytokines that have been associated with type 2 diabetes. Very few studies on role of circulatory IL-6 in diabetes have been published in Indians. This study aims to determine the serum levels of IL-6 in diabetic patients and compare them with healthy controls. We hypothesized that circulating IL-6 levels increases in diabetes due to underline chronic inflammation. Conclusion: Our results concluded that increased serum IL-6 levels compared to normal controls might be associated with inflammation related pathophysiology in type 2 diabetes.

International Journal of Basic and Clinical Pharmacology, 2015

Vitamin D deficiency, as reflected by circulating 25-hydroxyvitamin D (25[OH]D) levels <20 ng/ml,... more Vitamin D deficiency, as reflected by circulating 25-hydroxyvitamin D (25[OH]D) levels <20 ng/ml, is prevalent in as many as one-half of middle-aged to elderly adults in developed countries. 1,2 The ubiquitous distribution of Vitamin D receptors in the body, controlled by nearly 3000 genes, 3,4 suggest that a deficiency could have widespread health consequences. Thus, understanding the characteristics that promote Vitamin D deficiency in the general population has important clinical implications. Vitamin D deficiency is estimated to affect over 1 billion people worldwide, 1 and its prevalence is increasing in conjunction with Type 2 diabetes (T2D), obesity, and derangements in metabolic traits. Recent studies have examined the physiological functions of Vitamin D beyond its well-established role in musculoskeletal health. 5 In addition to findings of oncologic 4 and immunologic 5 associations, Vitamin D deficiency is associated with metabolic derangements and T2D. 6-8 Although 1, 25(OH)D is the active form of Vitamin D, it is not suitable for measuring Vitamin D serum level. 25(OH)D has a longer half-life and it can more precisely show the food intake and skin production of Vitamin D. A serum level of <20 ng/ml (50 nmol/L) 25(OH)D is considered as Vitamin D deficiency, between 20 and 30 ng/ml as its insufficient level and higher than 30 ng/ml as its desirable or sufficient level. 9-11