Vidisha Sharma - Academia.edu (original) (raw)

Vidisha  Sharma

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Papers by Vidisha Sharma

Research paper thumbnail of Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents

Bioorganic & Medicinal Chemistry Letters, 2009

Research paper thumbnail of Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents

a b s t r a c t 4-(Substituted-benzylidine)-2-substituted-5,6-dihydrobenzo[h]quinazoline (5a-p) a... more a b s t r a c t 4-(Substituted-benzylidine)-2-substituted-5,6-dihydrobenzo[h]quinazoline (5a-p) and 4-(substitutedbenzylidine)-2-substituted-3, 4, 5, 6-tetrahydrobenzo[h]quinazoline (6a-p) have been synthesized from 2-(substituted-benzylidine)tetralone-1(3a-d) and several substituted guanidine sulfates(4a-d).These compounds were tested for their in vitro antileishmanial activity. The compounds 6i, 6f, 6g show promising antileishmanial activity against Leishmania donovani.

Research paper thumbnail of Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents

Bioorganic & Medicinal Chemistry Letters, 2009

Research paper thumbnail of Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents

a b s t r a c t 4-(Substituted-benzylidine)-2-substituted-5,6-dihydrobenzo[h]quinazoline (5a-p) a... more a b s t r a c t 4-(Substituted-benzylidine)-2-substituted-5,6-dihydrobenzo[h]quinazoline (5a-p) and 4-(substitutedbenzylidine)-2-substituted-3, 4, 5, 6-tetrahydrobenzo[h]quinazoline (6a-p) have been synthesized from 2-(substituted-benzylidine)tetralone-1(3a-d) and several substituted guanidine sulfates(4a-d).These compounds were tested for their in vitro antileishmanial activity. The compounds 6i, 6f, 6g show promising antileishmanial activity against Leishmania donovani.

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