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Vidya Tamhankar

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Research paper thumbnail of Impact of Emotional Health on Pregnancy Rates Following Assisted Conception

Research paper thumbnail of Impact of Emotional Health on Pregnancy Rates Following Assisted Conception

Infertility can be stressful and hence it is important to know whether this stress can affect the... more Infertility can be stressful and hence it is important to know whether this stress can affect the success of in vitro fertilisation (IVF). Several studies have suggested a link between stress and reproduction. A systematic literature review concluded that the available evidence is inconclusive due to methodological limitations. It highlighted the need for a prospective well-designed study to examine the impact of emotional health on IVF outcome. Fertility specific tools were critically analysed in order to choose an appropriate instrument for the study. A prospective study was designed to evaluate the emotional health and distress prior to treatment. The questionnaires used were Emotional health in infertility (EM-INFERT) and Fertility problem inventory (FPI). The primary objective was to correlate the emotional health scores to the pregnancy rates. 414 IVF patients were divided into three tertiles as per their EM-INFERT scores: poor emotional health (n=140), average emotional healt...

Research paper thumbnail of Can pre-treatment emotional health predict pregnancy rates after IVF?

Research paper thumbnail of A Comparison of Pattern of Pregnancy Loss in Women with Infertility Undergoing IVF and Women with Unexplained Recurrent Miscarriages Who Conceive Spontaneously

Obstetrics and Gynecology International, 2015

Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. Th... more Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. The aim of this study was to compare the pregnancy loss in pregnancies after IVF treatment with spontaneous pregnancies in women with recurrent miscarriages and to assess differences related to cause of infertility.Methods. The outcome from 1220 IVF pregnancies (Group I) was compared with 611 spontaneous pregnancies (Group II) in women with recurrent miscarriages. Subgroup analysis was performed in Group I based on cause of infertility: tubal factor (392 pregnancies); male factor (610 pregnancies); and unexplained infertility (218 pregnancies).Results. The clinical pregnancy loss rate in Group I (14.3%) was significantly lower than that of Group II (25.8%,p<0.001) and this was independent of the cause of infertility. However the timing of pregnancy loss was similar between Groups I and II. The clinical pregnancy loss rate in Group I was similar in different causes of infertility.Conclus...

Research paper thumbnail of Seasonal variation in the incidence of preeclampsia and eclampsia in tropical climatic conditions

BMC Women's Health, 2007

Background: Observational studies have demonstrated various correlations between hypertensive dis... more Background: Observational studies have demonstrated various correlations between hypertensive disorders of pregnancy and different weather parameters. We aim to study if a correlation exists between the incidence of eclampsia and pre-eclampsia and various weather parameters in the tropical coastal city of Mumbai which has the distinction of having relatively uniform meteorological variables all throughout the year, except for the monsoon season. Methods: We retrospectively analysed data from a large maternity centre in Mumbai, India over a period of 36 months from March 1993 to February 1996, recording the incidence of preeclampsia and eclampsia. Meteorological data was acquired from the regional meteorological centre recording the monthly average temperature, humidity, barometric pressure and rainfall during the study period. Study period was then divided into two climate conditions: monsoon season (June to August) and dry season September to May. The incidence of preeclampsia and eclampsia and the meteorological differences between the two seasons were compared. Results: Over a 36-month period, a total of 29562 deliveries were recorded, of which 1238 patients developed preeclampsia (4.18%) and 34 developed eclampsia (0.11%). The incidence of preeclampsia did not differ between the monsoon and the dry season (4.3% vs. 4.15%, p = 0.5). The incidence of eclampsia was significantly higher in the monsoon (0.2% vs. 0.08%, p = 0.01). The monsoon was significantly cooler (median maximum temperature 30.7°C vs. 32.3°C, p = 0.01), more humid (median relative humidity 85% vs. 70%, p = 0.0008), and received higher rainfall (median 504.9 mm vs. 0.3 mm, p = 0.0002) than the rest of the year. The median barometric pressure (1005 mb) during the monsoon season was significantly lower than the rest of the year (1012 mb, p < 0.0001). Conclusion: In the tropical climate of Mumbai, the incidence of eclampsia is significantly higher in monsoon, when the weather is cooler and humid with a lower barometric pressure than the rest of the year. This effect is not seen with preeclampsia. This strengthens the association of low temperature and high humidity with triggering of eclampsia.

Research paper thumbnail of Impact of Emotional Health on Pregnancy Rates Following Assisted Conception

Research paper thumbnail of Impact of Emotional Health on Pregnancy Rates Following Assisted Conception

Infertility can be stressful and hence it is important to know whether this stress can affect the... more Infertility can be stressful and hence it is important to know whether this stress can affect the success of in vitro fertilisation (IVF). Several studies have suggested a link between stress and reproduction. A systematic literature review concluded that the available evidence is inconclusive due to methodological limitations. It highlighted the need for a prospective well-designed study to examine the impact of emotional health on IVF outcome. Fertility specific tools were critically analysed in order to choose an appropriate instrument for the study. A prospective study was designed to evaluate the emotional health and distress prior to treatment. The questionnaires used were Emotional health in infertility (EM-INFERT) and Fertility problem inventory (FPI). The primary objective was to correlate the emotional health scores to the pregnancy rates. 414 IVF patients were divided into three tertiles as per their EM-INFERT scores: poor emotional health (n=140), average emotional healt...

Research paper thumbnail of Can pre-treatment emotional health predict pregnancy rates after IVF?

Research paper thumbnail of A Comparison of Pattern of Pregnancy Loss in Women with Infertility Undergoing IVF and Women with Unexplained Recurrent Miscarriages Who Conceive Spontaneously

Obstetrics and Gynecology International, 2015

Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. Th... more Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. The aim of this study was to compare the pregnancy loss in pregnancies after IVF treatment with spontaneous pregnancies in women with recurrent miscarriages and to assess differences related to cause of infertility.Methods. The outcome from 1220 IVF pregnancies (Group I) was compared with 611 spontaneous pregnancies (Group II) in women with recurrent miscarriages. Subgroup analysis was performed in Group I based on cause of infertility: tubal factor (392 pregnancies); male factor (610 pregnancies); and unexplained infertility (218 pregnancies).Results. The clinical pregnancy loss rate in Group I (14.3%) was significantly lower than that of Group II (25.8%,p<0.001) and this was independent of the cause of infertility. However the timing of pregnancy loss was similar between Groups I and II. The clinical pregnancy loss rate in Group I was similar in different causes of infertility.Conclus...

Research paper thumbnail of Seasonal variation in the incidence of preeclampsia and eclampsia in tropical climatic conditions

BMC Women's Health, 2007

Background: Observational studies have demonstrated various correlations between hypertensive dis... more Background: Observational studies have demonstrated various correlations between hypertensive disorders of pregnancy and different weather parameters. We aim to study if a correlation exists between the incidence of eclampsia and pre-eclampsia and various weather parameters in the tropical coastal city of Mumbai which has the distinction of having relatively uniform meteorological variables all throughout the year, except for the monsoon season. Methods: We retrospectively analysed data from a large maternity centre in Mumbai, India over a period of 36 months from March 1993 to February 1996, recording the incidence of preeclampsia and eclampsia. Meteorological data was acquired from the regional meteorological centre recording the monthly average temperature, humidity, barometric pressure and rainfall during the study period. Study period was then divided into two climate conditions: monsoon season (June to August) and dry season September to May. The incidence of preeclampsia and eclampsia and the meteorological differences between the two seasons were compared. Results: Over a 36-month period, a total of 29562 deliveries were recorded, of which 1238 patients developed preeclampsia (4.18%) and 34 developed eclampsia (0.11%). The incidence of preeclampsia did not differ between the monsoon and the dry season (4.3% vs. 4.15%, p = 0.5). The incidence of eclampsia was significantly higher in the monsoon (0.2% vs. 0.08%, p = 0.01). The monsoon was significantly cooler (median maximum temperature 30.7°C vs. 32.3°C, p = 0.01), more humid (median relative humidity 85% vs. 70%, p = 0.0008), and received higher rainfall (median 504.9 mm vs. 0.3 mm, p = 0.0002) than the rest of the year. The median barometric pressure (1005 mb) during the monsoon season was significantly lower than the rest of the year (1012 mb, p < 0.0001). Conclusion: In the tropical climate of Mumbai, the incidence of eclampsia is significantly higher in monsoon, when the weather is cooler and humid with a lower barometric pressure than the rest of the year. This effect is not seen with preeclampsia. This strengthens the association of low temperature and high humidity with triggering of eclampsia.

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