S. Villalpando - Academia.edu (original) (raw)

Papers by S. Villalpando

Salud Pública de México, 2003

Estado de las vitaminas A y C, y folato en niños menores de 12 años de edad y mujeres de entre 12... more Estado de las vitaminas A y C, y folato en niños menores de 12 años de edad y mujeres de entre 12 a 49 años de edad. Una encuesta probabilística nacional. Salud Publica Mex 2003;45 supl 4:S508-S519. El texto completo en inglés de este artículo también está disponible en: http://www.insp.mx/salud/index.html

cdsweb.cern.ch

Ziemann, Volker; Andersson, Lars Olof; Bergmark, Torsten; Bystrom, Olle; Calen, Hans; Einarsson, ... more Ziemann, Volker; Andersson, Lars Olof; Bergmark, Torsten; Bystrom, Olle; Calen, Hans; Einarsson, Lars; Ekström, Curt; Fransson, Johan; Gajewski, Konrad; Haag, Nicole; Hartman, Torbjörn; Hellbeck, Elin; Johansen, Trygve; Jonsson, Olle; Lundström, Bengt; Peterson, ...

Archives of medical research, 1994

A fluorometric assay for determining lipoprotein lipase (LPL) activity is described. Dibutyrilflu... more A fluorometric assay for determining lipoprotein lipase (LPL) activity is described. Dibutyrilfluorescine (DBF) was used as substrate for the enzyme and the fluoresceine liberated by enzymatic hydrolysis of the substrate was measured. Extracts of acetone powder from adipose tissue as an enzyme source showed characteristics of lipoprotein lipase activity, i.e., inhibition by NaCl and optimum activity in alkaline pH. There was close agreement in LPL activity when the same sample was measured simultaneously using either dibutyrilfluorescine or tri[9,10(3)H]oleylglycerol as substrate. The extent of inhibition of lipoprotein lipase by NaCl was similar with both methods. The fluorometric method detected changes in LPL activity in heart and adipose tissue related to the nutritional status of the animal with the same specificity and sensitivity than did the radioactive method. The fluorometric method is as sensitive, less expensive and less time consuming than the radioactive method.

International Encyclopedia of Public Health, 2008

Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición

Information on nutritional status of the rural Mexican population is mostly obtained from cross-s... more Information on nutritional status of the rural Mexican population is mostly obtained from cross-sectional studies. This investigation evaluates semi-longitudinally the nutritional level of a sample of the rural population of Mexico. A total of 15,552 individuals in 2,587 households from 208 rural communities were evaluated. Body weight and height of rural boys and girls were found to be significantly lower than in their urban counterparts. Severe forms of weight for age or height for age inadequacy were more frequent in females than in males, in smaller communities than in larger ones, and in economically depressed zones than in those with a good economy. Our data showed a lower frequency of mild and moderate forms of possible malnutrition than previous studies (20 vs 50%) using as a criterion weight for age. These differences are explained on the basis of sampling bias.

Archivos de investigación médica

L'hypocalcemie est le resultat de l'incapacite de la parathormone de reponse correctement... more L'hypocalcemie est le resultat de l'incapacite de la parathormone de reponse correctement a la stimulation du calcium du en partie au role permissif du magnesium dans la chute de parathormone

Plasma zinc and pituitary and testicular hormone concentrations were measured in two groups of ma... more Plasma zinc and pituitary and testicular hormone concentrations were measured in two groups of male adolescents. One group comprised insulin-dependent diabetes mellitus patients, aged 14-19 years; the other, as control, included 12 healthy youngsters aged 13-19 years. Plasma concentration of zinc, prolactin, testosterone, and dihydrotestosterone were lower in diabetics than in controls, whereas the ratios of androstenedione and androstenedione to testosterone + dihydrogtestosterone were higher. Plasma FSH and LH were normal. These results suggest a diminished conversion of androstenedione to testosterone and relate zinc with the 17-0-hydroxysteroid dehydrogenase enzyme activity.

Salud Pública de México, 2010

Prevalence and distribution of type 2 Diabetes mellitus in Mexican adult population. A probabilis... more Prevalence and distribution of type 2 Diabetes mellitus in Mexican adult population. A probabilistic survey.

Salud Pública de México, 2009

Objective. To compare the distribution of anemia in children, based on information from Mexican N... more Objective. To compare the distribution of anemia in children, based on information from Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006) and Mexican National Nutrition Survey 1999 (ENN-99), and examine the association of anemia with potentially explanatory variables. Material and Methods. Adjusted prevalence and means as well as associations with potentially explanatory variables were assessed by multiple linear and logistic regression models for complex samples. Results. From 1999 to 2006, the prevalence of anemia decreased 13.8 percentage points (pp) in toddlers and 7.8 pp in children 24-35 months of age; it also decreased 0.7 pp/year in urban and rural populations, 1.8 pp/year in indigenous and 0.61 pp/year in non-indigenous toddlers, 1.5 pp/ year in children 5-8 years of age and 0.78 pp/year in children 9-11 years of age. In toddlers served by Oportunidades, Hb was inversely associated with indigenous ethnicity (p=0.1) and they had a lower risk of anemia (OR=0.002). In school-age children, age (OR=0.98), affiliation to Liconsa (OR=0.42) and living in the central region (OR=0.56) were protective factors for anemia. Conclusions. The national prevalence of anemia in Mexico has decreased in the past seven years, especially in toddlers. Being a beneficiary of Liconsa or Oportunidades was protective for anemia.

Salud Pública de México, 2009

Lancet (London, England), Jan 7, 2015

Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and year... more Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally...

Journal of the American Society of Nephrology, 2008

Salud Pública de México, 2012

American Journal of Clinical Nutrition, 2009

Salud publica de Mexico, 2021

OBJECTIVE To compare the prevalence of women 20-49 years of age with iron deficiency anemia (IDA)... more OBJECTIVE To compare the prevalence of women 20-49 years of age with iron deficiency anemia (IDA), iron deficiency with no anemia (IDNA), and non-ID anemia (NIDA) in com-parison during 2006, 2012 and 2018, and their association with sociodemographic characteristics and nutritional status. MATERIALS AND METHODS Ensanut 2006, 2012 and 2018- 19 are comparable for measurements of anemia (hemoglobin) and Iron deficiency (ID, by ferritin). Both measurements combined were compared with year of surveys and other dependent variables using a multinomial regression. RESULTS In 2006, the total prevalence of anemia was 14.9% and ID 29.0%, the prevalence of IDA was 8.35%, of IDNA 20.5%, and NIDA 6.6%; in 2012, the total prevalence of anemia was 13.3%, ID was 9.6%, IDA 8.6%, IDNA 21.0% y NIDA 4.7%; in 2018 total prevalence of anemia was 21.4%, of ID 25.7%, IDA 10.5%, IDNA 15.2% and NIDA 10.9%. CONCLUSIONS The total prevalence of anemia increased 6.5 pp between 2006 and 2018, IDNA reduced, IDA had ...

Journal of Food Science, 2007

As part of the efforts to reduce iron deficiency anemia (IDA), the Mexican Federal program PROGRE... more As part of the efforts to reduce iron deficiency anemia (IDA), the Mexican Federal program PROGRESA distributes complementary foods to toddlers and pregnant women living in extreme poverty. Complementary foods were originally fortified with hydrogen-reduced iron, which proved a limited efficacy. The supplement was reformulated to provide higher iron bioavailability. This investigation aims to assess the sensory changes and the acceptance of new versions of the complementary foods fortified with either reduced iron, ferrous fumarate, or ferrous sulfate, stored at room temperature for 2, 4, and 6 mo. Complementary foods were presented without flavor (plain) or flavored with either chocolate or vanilla. The complementary foods were evaluated in toddlers and their mothers using a hedonic scale. The percentage of overall acceptance for the baby foods was higher in toddlers (80% to 88%) than in their mothers (63% to 68%). The complementary foods with a better acceptance were those fortified with reduced iron (63% to 68%) and ferrous fumarate (61% to 80%) independently of the flavoring added. The acceptance of the beverage intended for women was better for those fortified with reduced iron (52% to 63%) or ferrous fumarate (44% to 63%) in their vanilla-flavored version. For women, the most accepted sources of iron were reduced iron (50% to 60%) and ferrous fumarate (50% to 58%).

OBJECTIVE To describe the current status of micronutrient deficiencies (MD) and anemia in Mexican... more OBJECTIVE To describe the current status of micronutrient deficiencies (MD) and anemia in Mexican children. MATERIALS AND METHODS Serum data from 1 382 pre-school-age chil-dren (1-4 years) and 3 590 school-age children (5-11 years) Ensanut 2018-19 participants were analyzed. Iron deficiency (ID), vitamin B12 deficiency (B12D), vitamin A depletion (VADp), and anemia were identified. Logistic regression models were used to identify associations between socio-demographic characteristics of children and MD. RESULTS Anemia was present in 28.9 and 19.2% of the children aged 1-4 and 5-11, respectively; in ID 10 and 5.1%; B12D, in 5.1 and 4.8%, and VADp, in 4.7 and 4.3%. 18.5% of the preschool-age children and 13% of the school-age children had at least one MD associated to anemia. CONCLUSIONS MD and anemia affect the younger children in larger proportion. Fortification and supplementation programs should be reinforced to avoid the long-term consequences of MD.

Salud Publica De Mexico, 2013

Objective. To describe the prevalence of anemia in Mexican children and adolescents from ENSANUT ... more Objective. To describe the prevalence of anemia in Mexican children and adolescents from ENSANUT 2012. Materials and methods. Data had the power to make distinctions at the national, regional and rural/urban dwelling. Hemoglobin was measured by Hemocue. Descriptions were made by adjusted frequencies and 95%CI. Confounders were tested in a logistic regression models. Results. The prevalence of anemia in 2012 was: in children 1-4 y, 23.3%; 5-11y, 10.1%, and 12-19 y, 5.6%. The prevalence in female adolescents was 7.7% and 3.6% in males. Reductions in the prevalence of anemia from 1999 was 8.3pp in <5y, 5.1pp in children 5-11y and 3.6pp from 2006 in adolescents. Conclusions. Despite the decrease in the prevalence of anemia in children 1-4 y in the last 13 years, it still is of great concern. There is a need of awareness among social and medical communities about this, to extend the distribution of micronutrient supplements in children <3y, and to promote nutritional education to i...

Salud publica de Mexico, 2012

OBJECTIVE To present an overview of micronutrient status of Mexican children in 2006. MATERIALS A... more OBJECTIVE To present an overview of micronutrient status of Mexican children in 2006. MATERIALS AND METHODS Data on iron, zinc, folate and vitamin B12 deficiencies and low serum copper and magnesium were gathered and critically analyzed from the 2006 National Health and Nutrition Survey. RESULTS Iron deficiency is still the main nutritional deficiency in children (13%-26%). Zinc deficiency was high in all age groups (≈25%) but reduced 5.6 PP in children <5 y from 1999 to 2006. Folate deficiency was 3.2% and vitamin B12 deficiency 7.7% in children. Low serum magnesium and copper were high (22.6% and 30.6%, respectively). CONCLUSIONS The prevalence of iron deficiency seems to be lowering, and zinc deficiency has reduced in Mexican children. A high prevalence of copper and magnesium deficiencies warrants further research on their public health implications.

Salud Pública de México, 2003

Estado de las vitaminas A y C, y folato en niños menores de 12 años de edad y mujeres de entre 12... more Estado de las vitaminas A y C, y folato en niños menores de 12 años de edad y mujeres de entre 12 a 49 años de edad. Una encuesta probabilística nacional. Salud Publica Mex 2003;45 supl 4:S508-S519. El texto completo en inglés de este artículo también está disponible en: http://www.insp.mx/salud/index.html

cdsweb.cern.ch

Ziemann, Volker; Andersson, Lars Olof; Bergmark, Torsten; Bystrom, Olle; Calen, Hans; Einarsson, ... more Ziemann, Volker; Andersson, Lars Olof; Bergmark, Torsten; Bystrom, Olle; Calen, Hans; Einarsson, Lars; Ekström, Curt; Fransson, Johan; Gajewski, Konrad; Haag, Nicole; Hartman, Torbjörn; Hellbeck, Elin; Johansen, Trygve; Jonsson, Olle; Lundström, Bengt; Peterson, ...

Archives of medical research, 1994

A fluorometric assay for determining lipoprotein lipase (LPL) activity is described. Dibutyrilflu... more A fluorometric assay for determining lipoprotein lipase (LPL) activity is described. Dibutyrilfluorescine (DBF) was used as substrate for the enzyme and the fluoresceine liberated by enzymatic hydrolysis of the substrate was measured. Extracts of acetone powder from adipose tissue as an enzyme source showed characteristics of lipoprotein lipase activity, i.e., inhibition by NaCl and optimum activity in alkaline pH. There was close agreement in LPL activity when the same sample was measured simultaneously using either dibutyrilfluorescine or tri[9,10(3)H]oleylglycerol as substrate. The extent of inhibition of lipoprotein lipase by NaCl was similar with both methods. The fluorometric method detected changes in LPL activity in heart and adipose tissue related to the nutritional status of the animal with the same specificity and sensitivity than did the radioactive method. The fluorometric method is as sensitive, less expensive and less time consuming than the radioactive method.

International Encyclopedia of Public Health, 2008

Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición

Information on nutritional status of the rural Mexican population is mostly obtained from cross-s... more Information on nutritional status of the rural Mexican population is mostly obtained from cross-sectional studies. This investigation evaluates semi-longitudinally the nutritional level of a sample of the rural population of Mexico. A total of 15,552 individuals in 2,587 households from 208 rural communities were evaluated. Body weight and height of rural boys and girls were found to be significantly lower than in their urban counterparts. Severe forms of weight for age or height for age inadequacy were more frequent in females than in males, in smaller communities than in larger ones, and in economically depressed zones than in those with a good economy. Our data showed a lower frequency of mild and moderate forms of possible malnutrition than previous studies (20 vs 50%) using as a criterion weight for age. These differences are explained on the basis of sampling bias.

Archivos de investigación médica

L'hypocalcemie est le resultat de l'incapacite de la parathormone de reponse correctement... more L'hypocalcemie est le resultat de l'incapacite de la parathormone de reponse correctement a la stimulation du calcium du en partie au role permissif du magnesium dans la chute de parathormone

Plasma zinc and pituitary and testicular hormone concentrations were measured in two groups of ma... more Plasma zinc and pituitary and testicular hormone concentrations were measured in two groups of male adolescents. One group comprised insulin-dependent diabetes mellitus patients, aged 14-19 years; the other, as control, included 12 healthy youngsters aged 13-19 years. Plasma concentration of zinc, prolactin, testosterone, and dihydrotestosterone were lower in diabetics than in controls, whereas the ratios of androstenedione and androstenedione to testosterone + dihydrogtestosterone were higher. Plasma FSH and LH were normal. These results suggest a diminished conversion of androstenedione to testosterone and relate zinc with the 17-0-hydroxysteroid dehydrogenase enzyme activity.

Salud Pública de México, 2010

Prevalence and distribution of type 2 Diabetes mellitus in Mexican adult population. A probabilis... more Prevalence and distribution of type 2 Diabetes mellitus in Mexican adult population. A probabilistic survey.

Salud Pública de México, 2009

Objective. To compare the distribution of anemia in children, based on information from Mexican N... more Objective. To compare the distribution of anemia in children, based on information from Mexican National Health and Nutrition Survey 2006 (ENSANUT 2006) and Mexican National Nutrition Survey 1999 (ENN-99), and examine the association of anemia with potentially explanatory variables. Material and Methods. Adjusted prevalence and means as well as associations with potentially explanatory variables were assessed by multiple linear and logistic regression models for complex samples. Results. From 1999 to 2006, the prevalence of anemia decreased 13.8 percentage points (pp) in toddlers and 7.8 pp in children 24-35 months of age; it also decreased 0.7 pp/year in urban and rural populations, 1.8 pp/year in indigenous and 0.61 pp/year in non-indigenous toddlers, 1.5 pp/ year in children 5-8 years of age and 0.78 pp/year in children 9-11 years of age. In toddlers served by Oportunidades, Hb was inversely associated with indigenous ethnicity (p=0.1) and they had a lower risk of anemia (OR=0.002). In school-age children, age (OR=0.98), affiliation to Liconsa (OR=0.42) and living in the central region (OR=0.56) were protective factors for anemia. Conclusions. The national prevalence of anemia in Mexico has decreased in the past seven years, especially in toddlers. Being a beneficiary of Liconsa or Oportunidades was protective for anemia.

Salud Pública de México, 2009

Lancet (London, England), Jan 7, 2015

Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and year... more Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally...

Journal of the American Society of Nephrology, 2008

Salud Pública de México, 2012

American Journal of Clinical Nutrition, 2009

Salud publica de Mexico, 2021

OBJECTIVE To compare the prevalence of women 20-49 years of age with iron deficiency anemia (IDA)... more OBJECTIVE To compare the prevalence of women 20-49 years of age with iron deficiency anemia (IDA), iron deficiency with no anemia (IDNA), and non-ID anemia (NIDA) in com-parison during 2006, 2012 and 2018, and their association with sociodemographic characteristics and nutritional status. MATERIALS AND METHODS Ensanut 2006, 2012 and 2018- 19 are comparable for measurements of anemia (hemoglobin) and Iron deficiency (ID, by ferritin). Both measurements combined were compared with year of surveys and other dependent variables using a multinomial regression. RESULTS In 2006, the total prevalence of anemia was 14.9% and ID 29.0%, the prevalence of IDA was 8.35%, of IDNA 20.5%, and NIDA 6.6%; in 2012, the total prevalence of anemia was 13.3%, ID was 9.6%, IDA 8.6%, IDNA 21.0% y NIDA 4.7%; in 2018 total prevalence of anemia was 21.4%, of ID 25.7%, IDA 10.5%, IDNA 15.2% and NIDA 10.9%. CONCLUSIONS The total prevalence of anemia increased 6.5 pp between 2006 and 2018, IDNA reduced, IDA had ...

Journal of Food Science, 2007

As part of the efforts to reduce iron deficiency anemia (IDA), the Mexican Federal program PROGRE... more As part of the efforts to reduce iron deficiency anemia (IDA), the Mexican Federal program PROGRESA distributes complementary foods to toddlers and pregnant women living in extreme poverty. Complementary foods were originally fortified with hydrogen-reduced iron, which proved a limited efficacy. The supplement was reformulated to provide higher iron bioavailability. This investigation aims to assess the sensory changes and the acceptance of new versions of the complementary foods fortified with either reduced iron, ferrous fumarate, or ferrous sulfate, stored at room temperature for 2, 4, and 6 mo. Complementary foods were presented without flavor (plain) or flavored with either chocolate or vanilla. The complementary foods were evaluated in toddlers and their mothers using a hedonic scale. The percentage of overall acceptance for the baby foods was higher in toddlers (80% to 88%) than in their mothers (63% to 68%). The complementary foods with a better acceptance were those fortified with reduced iron (63% to 68%) and ferrous fumarate (61% to 80%) independently of the flavoring added. The acceptance of the beverage intended for women was better for those fortified with reduced iron (52% to 63%) or ferrous fumarate (44% to 63%) in their vanilla-flavored version. For women, the most accepted sources of iron were reduced iron (50% to 60%) and ferrous fumarate (50% to 58%).

OBJECTIVE To describe the current status of micronutrient deficiencies (MD) and anemia in Mexican... more OBJECTIVE To describe the current status of micronutrient deficiencies (MD) and anemia in Mexican children. MATERIALS AND METHODS Serum data from 1 382 pre-school-age chil-dren (1-4 years) and 3 590 school-age children (5-11 years) Ensanut 2018-19 participants were analyzed. Iron deficiency (ID), vitamin B12 deficiency (B12D), vitamin A depletion (VADp), and anemia were identified. Logistic regression models were used to identify associations between socio-demographic characteristics of children and MD. RESULTS Anemia was present in 28.9 and 19.2% of the children aged 1-4 and 5-11, respectively; in ID 10 and 5.1%; B12D, in 5.1 and 4.8%, and VADp, in 4.7 and 4.3%. 18.5% of the preschool-age children and 13% of the school-age children had at least one MD associated to anemia. CONCLUSIONS MD and anemia affect the younger children in larger proportion. Fortification and supplementation programs should be reinforced to avoid the long-term consequences of MD.

Salud Publica De Mexico, 2013

Objective. To describe the prevalence of anemia in Mexican children and adolescents from ENSANUT ... more Objective. To describe the prevalence of anemia in Mexican children and adolescents from ENSANUT 2012. Materials and methods. Data had the power to make distinctions at the national, regional and rural/urban dwelling. Hemoglobin was measured by Hemocue. Descriptions were made by adjusted frequencies and 95%CI. Confounders were tested in a logistic regression models. Results. The prevalence of anemia in 2012 was: in children 1-4 y, 23.3%; 5-11y, 10.1%, and 12-19 y, 5.6%. The prevalence in female adolescents was 7.7% and 3.6% in males. Reductions in the prevalence of anemia from 1999 was 8.3pp in <5y, 5.1pp in children 5-11y and 3.6pp from 2006 in adolescents. Conclusions. Despite the decrease in the prevalence of anemia in children 1-4 y in the last 13 years, it still is of great concern. There is a need of awareness among social and medical communities about this, to extend the distribution of micronutrient supplements in children <3y, and to promote nutritional education to i...

Salud publica de Mexico, 2012

OBJECTIVE To present an overview of micronutrient status of Mexican children in 2006. MATERIALS A... more OBJECTIVE To present an overview of micronutrient status of Mexican children in 2006. MATERIALS AND METHODS Data on iron, zinc, folate and vitamin B12 deficiencies and low serum copper and magnesium were gathered and critically analyzed from the 2006 National Health and Nutrition Survey. RESULTS Iron deficiency is still the main nutritional deficiency in children (13%-26%). Zinc deficiency was high in all age groups (≈25%) but reduced 5.6 PP in children <5 y from 1999 to 2006. Folate deficiency was 3.2% and vitamin B12 deficiency 7.7% in children. Low serum magnesium and copper were high (22.6% and 30.6%, respectively). CONCLUSIONS The prevalence of iron deficiency seems to be lowering, and zinc deficiency has reduced in Mexican children. A high prevalence of copper and magnesium deficiencies warrants further research on their public health implications.