Wael Tawfick - Academia.edu (original) (raw)

Papers by Wael Tawfick

Journal of Tissue Viability, 2021

BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in t... more BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in the lower limbs. It is a recurring condition causing pain, malodour, reduced mobility, and depression. Randomised controlled trials evaluating treatments for venous leg ulcers provide important evidence to inform clinical decision-making. However, for findings to be useful, outcomes need to be clinically meaningful, consistently reported across trials, and fully reported. Research has identified the large number of outcomes reported in venous leg ulcer trials, impacting both synthesis of results, and clinical decision-making. To address this, a core outcome set will be developed. A core outcome set is an agreed standardised set of outcomes which should be, as a minimum, measured and reported in all trials which evaluate treatment effectiveness for a given indication. A core outcome set has the potential to reduce research waste, improve the utility of RCTs, reduce reporting bias, facilitate treatment comparisons across different sources of evidence and expedite the production of systematic reviews, meta-analyses and evidence-based clinical guidelines. AIM The aim of this project is to develop a core outcome set for research evaluating the effectiveness of interventions for treating venous leg ulceration. METHODS Through a scoping review of the literature on venous leg ulceration, we will firstly identify a list of candidate outcome domains (broad categories in relation to what is being measured) from randomised controlled trials and qualitative research, and outcomes (specific methods in relation to what is being measured). In two further stages, we will use the resulting lists of outcome domains and outcomes to design two online surveys. A range of stakeholders will be invited to participate in the surveys and they will be asked to indicate which outcome domains and outcomes are most important and should be considered as core in future research reports.

Journal of Tissue Viability, 2019

BACKGROUND To date, research into interventions to promote wound healing has been led by scientis... more BACKGROUND To date, research into interventions to promote wound healing has been led by scientists, clinicians, industry and academics, each with their own particular area of interest. However, the real experts in this area are the people who live with wounds and their families and heretofore their voice has not influenced or shaped the research agenda. AIM This event aimed to seek patient and carer involvement as experts due to their lived experience in wounds through a partnership approach to identify research priorities and address a lack of patient and carer involvement in wound care research. METHODS A roundtable discussion format guided by the Scottish Health Council Participation Toolkit Supporting Patient Focus and Public Involvement in NHS Scotland was utilised. The Guidance for Reporting Involvement of Patients and the Public 2 - Short Form (GRIPP2-SF) guided the reporting process. RESULTS Key areas for future research were identified and included; Patients and carers prioritised the establishment of support groups and the development of educational resources. Research priorities that emerged included understanding the impact of wounds, pain management, addressing educational needs and quantifying the financial burden on patients and carers of living with a wound. CONCLUSIONS A key conclusion from this roundtable was that patients and their carers expressed a strong interest in further wound care related public and patient involvement events and identified areas for future research.

CardioVascular and Interventional Radiology

Vascular Specialist International, 2020

Purpose: We compared the outcomes between the total endovascular approach using a unibody bifurca... more Purpose: We compared the outcomes between the total endovascular approach using a unibody bifurcated aortoiliac endograft and the gold standard aortobifemoral bypass (ABF) surgery for the management of extensive aortoiliac occlusive disease (AIOD). Materials and Methods: This retrospective observational study compared the outcomes of endovascular technique with unibody bifurcated endograft (UBE) using the Endologix AFX unibody stent-graft and a standard surgical approach (ABF) in the management of AIOD based on patient records in Western Vascular Institute,

Journal of Vascular Surgery, 2022

Irish Journal of Medical Science (1971 -), 2022

Background In December 2019, an outbreak of novel corona virus pneumonia occurred in Wuhan City, ... more Background In December 2019, an outbreak of novel corona virus pneumonia occurred in Wuhan City, China, and spread throughout the whole of country in a short period. Figures from China's National Health Commission show that more than 3300 health care workers have been infected as of early March. In Italy, 20% of responding health care professionals was infected, and some have died. Health care professionals are exposed to different types of stress both physical and psychological in response to this serious infectious public health event. Research aims The aim of this study is to measure the degree of mental stress among front line health care workers dealing with COVID-19 patients. Methods We conducted the study through online survey questionnaire after obtaining the ethics approval from the Research Ethics Committee of Galway University Hospital in Ireland (Ref: C.A. 2355). All personal information of the medical staff involved in the survey has been kept confidential. Results Three hundred nine health care members (209 male and 97 female) have agreed to participate in our survey from different hospitals and different specialties all over the world. Overall PSS Score: mean 19.42 (Standard Deviation ± 5.876, range 1-33). Frontline health care workers working in University Hospitals and tertiary referral centres had lower levels of stress compared to those working in peripheral hospitals (P = 0.007, Kruskal Wallis). Conclusion The COVID-19 pandemic is one of the most stressful events that a health care worker may face during his life time. Most of the participants in the survey developed a moderate degree of stress.

Italian Journal of Vascular and Endovascular Surgery, 2022

Cochrane Database of Systematic Reviews, 2018

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess... more This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of intermittent pneumatic compression for treatment of individuals with critical limb ischaemia.

International journal of scientific research, 2018

Purpose: To compare carotid artery endarterectomy (CEA) to trans-femoral carotid artery stenting ... more Purpose: To compare carotid artery endarterectomy (CEA) to trans-femoral carotid artery stenting (F-CAS) and trans-cervical carotid artery stenting (C-CAS). Primary endpoints are stroke, myocardial infarction (MI) or death within 30 days after the procedure. Secondary endpoints included patency, re-intervention rates and 5-year stroke free survival. Methods: Out of 9585 carotid patients referred, we performed 690 carotid interventions over 12 years. We matched 53 CEA and 53 CAS (34 F-CAS and 19 C-CAS) patients. Multiple logistic regressions were used to control for co-morbidity and anatomical high risk factors. Propensity scoring was used to adjust for baseline characteristics and selection bias, by matching co-variables. Results: Our total 30-day stroke/death for 690 carotid interventions was 0.9%. %. Thirty day stroke rate were 2.9%, 0% and 1.9% in the F-CAS, C-CAS and CEA respectably (P = .75). Thirty day MI was 0% in CAS group versus 1.9% in the CEA group (P = .32).Thirty-day m...

Journal of Tissue Viability, 2021

BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in t... more BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in the lower limbs. It is a recurring condition causing pain, malodour, reduced mobility, and depression. Randomised controlled trials evaluating treatments for venous leg ulcers provide important evidence to inform clinical decision-making. However, for findings to be useful, outcomes need to be clinically meaningful, consistently reported across trials, and fully reported. Research has identified the large number of outcomes reported in venous leg ulcer trials, impacting both synthesis of results, and clinical decision-making. To address this, a core outcome set will be developed. A core outcome set is an agreed standardised set of outcomes which should be, as a minimum, measured and reported in all trials which evaluate treatment effectiveness for a given indication. A core outcome set has the potential to reduce research waste, improve the utility of RCTs, reduce reporting bias, facilitate treatment comparisons across different sources of evidence and expedite the production of systematic reviews, meta-analyses and evidence-based clinical guidelines. AIM The aim of this project is to develop a core outcome set for research evaluating the effectiveness of interventions for treating venous leg ulceration. METHODS Through a scoping review of the literature on venous leg ulceration, we will firstly identify a list of candidate outcome domains (broad categories in relation to what is being measured) from randomised controlled trials and qualitative research, and outcomes (specific methods in relation to what is being measured). In two further stages, we will use the resulting lists of outcome domains and outcomes to design two online surveys. A range of stakeholders will be invited to participate in the surveys and they will be asked to indicate which outcome domains and outcomes are most important and should be considered as core in future research reports.

European Journal of Vascular and Endovascular Surgery, 2021

Annals of Vascular Surgery, 2021

Background: Endovascular therapy (EVT) is being adopted as a suitable first choice in the treatme... more Background: Endovascular therapy (EVT) is being adopted as a suitable first choice in the treatment of femoropopliteal disease. There are multiple factors affecting outcomes of EVT including distal runoff status. The aim of this study was to investigate the effect of runoff score on the outcomes of superficial femoral artery (SFA) endovascular interventions. Methods: Retrospective analysis was carried out on prospectively collected data on patients who underwent SFA endovascular intervention for critical limb ischemia. Patients with Rutherford categories 4 to 6 who had no previous vascular interventions were included. The modified SVS runoff score was used. Runoff was stratified into good (score <5), compromised (score 5-10), and poor (score >10). Amputation-free survival, patency rates and overall survival were compared at five years. Results: From 2011-2018, 254 procedures were performed on 220 patients. There was no significant difference between good, compromised, or poor runoff groups regarding complication rates, with 3.5% overall Perioperative mortality. Runoff score of <5 was associated with significantly marked clinical improvement (P<0.001). Patency rates were significantly worse in the compromised and poor runoff groups, with five-years cumulative primary patency rates of 80%, 50% and 22% in the good, compromised, and poor runoff groups, respectively (P<0.001). Amputation-free survival worsened as the runoff got poorer with 98%, 91% and 78% in the good, compromised, and poor runoff groups respectively at five years (P<0.001). Conclusions: Poor runoff with score of >10 was associated with significantly reduced amputation-free survival and patency rates at five years in patients undergoing SFA endovascular intervention for critical limb ischemia.

Atherosclerosis, 2020

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determ... more This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determine the e ectiveness of Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of CVD. Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases (Protocol)

Vessel Plus, 2020

Aim: We aimed to assess the clinical outcomes of the internal iliac artery (IIA) coverage during ... more Aim: We aimed to assess the clinical outcomes of the internal iliac artery (IIA) coverage during endovascular abdominal aortic aneurysm repair (EVAR). Methods: A retrospective observational study was conducted in patients managed with EVAR for the aorto-iliac aneurysmal disease. The IIA was sacrificed by extension of the stent-graft into the external iliac artery in the absence of the distal landing zone, while it was preserved if the landing zone was available. Results: From 2002 to 2018, 540 patients underwent EVAR for aorto-iliac aneurysmal disease in our center. Sixtyfive (12.04%, n = 65/540) had iliac aneurysm extension. Among these 65 cases, the IIA was not covered in 32 patients (IIA salvage/spared group), while they were covered in 33 patients (IIA sacrifice group). The IIA sacrifice group consisted of 25 unilateral and 8 bilateral coverages. There was 100% technical success and no 30-day mortality in both groups. The IIA sacrifice group had more postoperative complications in general when compared to the IIA salvage group, but they were not significant (P < 0.05). There were one patient with buttock claudication (P = 1.000) with bilateral IIA coverage, two cases of lower limb microembolization (P = 0.492) and one case of erectile dysfunction (P = 1.000) in IIA sacrifice group, while they were not seen in IIA salvage group. There was no ruptured iliac access, device-related malfunction, spinal cord ischemia or bowel ischemia in either group.

Journal of Evidence-Based Medicine, 2020

BACKGROUND Randomized trials are designed to evaluate the effects of health care interventions. T... more BACKGROUND Randomized trials are designed to evaluate the effects of health care interventions. The recruitment process in a randomized trial can be challenging. Poor recruitment can have a negative impact on the allocated budget and estimated completion date of the study and may result in an underpowered research that will not adequately answer the original research question. AIM We aim to perform a Study Within A Trial (SWAT) to evaluate the impact of same-day consent or delayed consent on recruitment and retention in the host trial. METHODS This SWAT is designed as an observational study. However, the host trial is a randomized controlled trial evaluating the effectiveness of an intensive lifestyle modification program in patients with peripheral arterial disease. For this trial and SWAT, same-day consent is defined as the patient giving consent on the same day, after the investigator has fully explained the predesigned information leaflet for the host trial. Delayed consent is defined as the patient feeling they still need further time to consider their decision to participate or not. SWAT REGISTRATION The SWAT was registered on the Northern Ireland Network for Trials Methodology Research.

Vascular and endovascular surgery, 2014

This case represents the first report of multiple arterial aneurysms including aortic, iliac, vis... more This case represents the first report of multiple arterial aneurysms including aortic, iliac, visceral, and coronary aneurysms associated with hypereosinophilic syndrome. It presents an interesting case of epinephrine abuse and the unfortunate sequelae. This case illustrates novel approaches in emergency repair of internal iliac artery aneurysm rupture and the management of visceral artery aneurysms and exemplifies how multiple endovascular technologies can be utilized even in the high-risk polymorbid patient.

Cochrane Database of Systematic Reviews, 2018

Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.

Journal of Tissue Viability, 2021

BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in t... more BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in the lower limbs. It is a recurring condition causing pain, malodour, reduced mobility, and depression. Randomised controlled trials evaluating treatments for venous leg ulcers provide important evidence to inform clinical decision-making. However, for findings to be useful, outcomes need to be clinically meaningful, consistently reported across trials, and fully reported. Research has identified the large number of outcomes reported in venous leg ulcer trials, impacting both synthesis of results, and clinical decision-making. To address this, a core outcome set will be developed. A core outcome set is an agreed standardised set of outcomes which should be, as a minimum, measured and reported in all trials which evaluate treatment effectiveness for a given indication. A core outcome set has the potential to reduce research waste, improve the utility of RCTs, reduce reporting bias, facilitate treatment comparisons across different sources of evidence and expedite the production of systematic reviews, meta-analyses and evidence-based clinical guidelines. AIM The aim of this project is to develop a core outcome set for research evaluating the effectiveness of interventions for treating venous leg ulceration. METHODS Through a scoping review of the literature on venous leg ulceration, we will firstly identify a list of candidate outcome domains (broad categories in relation to what is being measured) from randomised controlled trials and qualitative research, and outcomes (specific methods in relation to what is being measured). In two further stages, we will use the resulting lists of outcome domains and outcomes to design two online surveys. A range of stakeholders will be invited to participate in the surveys and they will be asked to indicate which outcome domains and outcomes are most important and should be considered as core in future research reports.

Journal of Tissue Viability, 2019

BACKGROUND To date, research into interventions to promote wound healing has been led by scientis... more BACKGROUND To date, research into interventions to promote wound healing has been led by scientists, clinicians, industry and academics, each with their own particular area of interest. However, the real experts in this area are the people who live with wounds and their families and heretofore their voice has not influenced or shaped the research agenda. AIM This event aimed to seek patient and carer involvement as experts due to their lived experience in wounds through a partnership approach to identify research priorities and address a lack of patient and carer involvement in wound care research. METHODS A roundtable discussion format guided by the Scottish Health Council Participation Toolkit Supporting Patient Focus and Public Involvement in NHS Scotland was utilised. The Guidance for Reporting Involvement of Patients and the Public 2 - Short Form (GRIPP2-SF) guided the reporting process. RESULTS Key areas for future research were identified and included; Patients and carers prioritised the establishment of support groups and the development of educational resources. Research priorities that emerged included understanding the impact of wounds, pain management, addressing educational needs and quantifying the financial burden on patients and carers of living with a wound. CONCLUSIONS A key conclusion from this roundtable was that patients and their carers expressed a strong interest in further wound care related public and patient involvement events and identified areas for future research.

CardioVascular and Interventional Radiology

Vascular Specialist International, 2020

Purpose: We compared the outcomes between the total endovascular approach using a unibody bifurca... more Purpose: We compared the outcomes between the total endovascular approach using a unibody bifurcated aortoiliac endograft and the gold standard aortobifemoral bypass (ABF) surgery for the management of extensive aortoiliac occlusive disease (AIOD). Materials and Methods: This retrospective observational study compared the outcomes of endovascular technique with unibody bifurcated endograft (UBE) using the Endologix AFX unibody stent-graft and a standard surgical approach (ABF) in the management of AIOD based on patient records in Western Vascular Institute,

Journal of Vascular Surgery, 2022

Irish Journal of Medical Science (1971 -), 2022

Background In December 2019, an outbreak of novel corona virus pneumonia occurred in Wuhan City, ... more Background In December 2019, an outbreak of novel corona virus pneumonia occurred in Wuhan City, China, and spread throughout the whole of country in a short period. Figures from China's National Health Commission show that more than 3300 health care workers have been infected as of early March. In Italy, 20% of responding health care professionals was infected, and some have died. Health care professionals are exposed to different types of stress both physical and psychological in response to this serious infectious public health event. Research aims The aim of this study is to measure the degree of mental stress among front line health care workers dealing with COVID-19 patients. Methods We conducted the study through online survey questionnaire after obtaining the ethics approval from the Research Ethics Committee of Galway University Hospital in Ireland (Ref: C.A. 2355). All personal information of the medical staff involved in the survey has been kept confidential. Results Three hundred nine health care members (209 male and 97 female) have agreed to participate in our survey from different hospitals and different specialties all over the world. Overall PSS Score: mean 19.42 (Standard Deviation ± 5.876, range 1-33). Frontline health care workers working in University Hospitals and tertiary referral centres had lower levels of stress compared to those working in peripheral hospitals (P = 0.007, Kruskal Wallis). Conclusion The COVID-19 pandemic is one of the most stressful events that a health care worker may face during his life time. Most of the participants in the survey developed a moderate degree of stress.

Italian Journal of Vascular and Endovascular Surgery, 2022

Cochrane Database of Systematic Reviews, 2018

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess... more This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of intermittent pneumatic compression for treatment of individuals with critical limb ischaemia.

International journal of scientific research, 2018

Purpose: To compare carotid artery endarterectomy (CEA) to trans-femoral carotid artery stenting ... more Purpose: To compare carotid artery endarterectomy (CEA) to trans-femoral carotid artery stenting (F-CAS) and trans-cervical carotid artery stenting (C-CAS). Primary endpoints are stroke, myocardial infarction (MI) or death within 30 days after the procedure. Secondary endpoints included patency, re-intervention rates and 5-year stroke free survival. Methods: Out of 9585 carotid patients referred, we performed 690 carotid interventions over 12 years. We matched 53 CEA and 53 CAS (34 F-CAS and 19 C-CAS) patients. Multiple logistic regressions were used to control for co-morbidity and anatomical high risk factors. Propensity scoring was used to adjust for baseline characteristics and selection bias, by matching co-variables. Results: Our total 30-day stroke/death for 690 carotid interventions was 0.9%. %. Thirty day stroke rate were 2.9%, 0% and 1.9% in the F-CAS, C-CAS and CEA respectably (P = .75). Thirty day MI was 0% in CAS group versus 1.9% in the CEA group (P = .32).Thirty-day m...

Journal of Tissue Viability, 2021

BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in t... more BACKGROUND A venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in the lower limbs. It is a recurring condition causing pain, malodour, reduced mobility, and depression. Randomised controlled trials evaluating treatments for venous leg ulcers provide important evidence to inform clinical decision-making. However, for findings to be useful, outcomes need to be clinically meaningful, consistently reported across trials, and fully reported. Research has identified the large number of outcomes reported in venous leg ulcer trials, impacting both synthesis of results, and clinical decision-making. To address this, a core outcome set will be developed. A core outcome set is an agreed standardised set of outcomes which should be, as a minimum, measured and reported in all trials which evaluate treatment effectiveness for a given indication. A core outcome set has the potential to reduce research waste, improve the utility of RCTs, reduce reporting bias, facilitate treatment comparisons across different sources of evidence and expedite the production of systematic reviews, meta-analyses and evidence-based clinical guidelines. AIM The aim of this project is to develop a core outcome set for research evaluating the effectiveness of interventions for treating venous leg ulceration. METHODS Through a scoping review of the literature on venous leg ulceration, we will firstly identify a list of candidate outcome domains (broad categories in relation to what is being measured) from randomised controlled trials and qualitative research, and outcomes (specific methods in relation to what is being measured). In two further stages, we will use the resulting lists of outcome domains and outcomes to design two online surveys. A range of stakeholders will be invited to participate in the surveys and they will be asked to indicate which outcome domains and outcomes are most important and should be considered as core in future research reports.

European Journal of Vascular and Endovascular Surgery, 2021

Annals of Vascular Surgery, 2021

Background: Endovascular therapy (EVT) is being adopted as a suitable first choice in the treatme... more Background: Endovascular therapy (EVT) is being adopted as a suitable first choice in the treatment of femoropopliteal disease. There are multiple factors affecting outcomes of EVT including distal runoff status. The aim of this study was to investigate the effect of runoff score on the outcomes of superficial femoral artery (SFA) endovascular interventions. Methods: Retrospective analysis was carried out on prospectively collected data on patients who underwent SFA endovascular intervention for critical limb ischemia. Patients with Rutherford categories 4 to 6 who had no previous vascular interventions were included. The modified SVS runoff score was used. Runoff was stratified into good (score <5), compromised (score 5-10), and poor (score >10). Amputation-free survival, patency rates and overall survival were compared at five years. Results: From 2011-2018, 254 procedures were performed on 220 patients. There was no significant difference between good, compromised, or poor runoff groups regarding complication rates, with 3.5% overall Perioperative mortality. Runoff score of <5 was associated with significantly marked clinical improvement (P<0.001). Patency rates were significantly worse in the compromised and poor runoff groups, with five-years cumulative primary patency rates of 80%, 50% and 22% in the good, compromised, and poor runoff groups, respectively (P<0.001). Amputation-free survival worsened as the runoff got poorer with 98%, 91% and 78% in the good, compromised, and poor runoff groups respectively at five years (P<0.001). Conclusions: Poor runoff with score of >10 was associated with significantly reduced amputation-free survival and patency rates at five years in patients undergoing SFA endovascular intervention for critical limb ischemia.

Atherosclerosis, 2020

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determ... more This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determine the e ectiveness of Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of CVD. Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases (Protocol)

Vessel Plus, 2020

Aim: We aimed to assess the clinical outcomes of the internal iliac artery (IIA) coverage during ... more Aim: We aimed to assess the clinical outcomes of the internal iliac artery (IIA) coverage during endovascular abdominal aortic aneurysm repair (EVAR). Methods: A retrospective observational study was conducted in patients managed with EVAR for the aorto-iliac aneurysmal disease. The IIA was sacrificed by extension of the stent-graft into the external iliac artery in the absence of the distal landing zone, while it was preserved if the landing zone was available. Results: From 2002 to 2018, 540 patients underwent EVAR for aorto-iliac aneurysmal disease in our center. Sixtyfive (12.04%, n = 65/540) had iliac aneurysm extension. Among these 65 cases, the IIA was not covered in 32 patients (IIA salvage/spared group), while they were covered in 33 patients (IIA sacrifice group). The IIA sacrifice group consisted of 25 unilateral and 8 bilateral coverages. There was 100% technical success and no 30-day mortality in both groups. The IIA sacrifice group had more postoperative complications in general when compared to the IIA salvage group, but they were not significant (P < 0.05). There were one patient with buttock claudication (P = 1.000) with bilateral IIA coverage, two cases of lower limb microembolization (P = 0.492) and one case of erectile dysfunction (P = 1.000) in IIA sacrifice group, while they were not seen in IIA salvage group. There was no ruptured iliac access, device-related malfunction, spinal cord ischemia or bowel ischemia in either group.

Journal of Evidence-Based Medicine, 2020

BACKGROUND Randomized trials are designed to evaluate the effects of health care interventions. T... more BACKGROUND Randomized trials are designed to evaluate the effects of health care interventions. The recruitment process in a randomized trial can be challenging. Poor recruitment can have a negative impact on the allocated budget and estimated completion date of the study and may result in an underpowered research that will not adequately answer the original research question. AIM We aim to perform a Study Within A Trial (SWAT) to evaluate the impact of same-day consent or delayed consent on recruitment and retention in the host trial. METHODS This SWAT is designed as an observational study. However, the host trial is a randomized controlled trial evaluating the effectiveness of an intensive lifestyle modification program in patients with peripheral arterial disease. For this trial and SWAT, same-day consent is defined as the patient giving consent on the same day, after the investigator has fully explained the predesigned information leaflet for the host trial. Delayed consent is defined as the patient feeling they still need further time to consider their decision to participate or not. SWAT REGISTRATION The SWAT was registered on the Northern Ireland Network for Trials Methodology Research.

Vascular and endovascular surgery, 2014

This case represents the first report of multiple arterial aneurysms including aortic, iliac, vis... more This case represents the first report of multiple arterial aneurysms including aortic, iliac, visceral, and coronary aneurysms associated with hypereosinophilic syndrome. It presents an interesting case of epinephrine abuse and the unfortunate sequelae. This case illustrates novel approaches in emergency repair of internal iliac artery aneurysm rupture and the management of visceral artery aneurysms and exemplifies how multiple endovascular technologies can be utilized even in the high-risk polymorbid patient.

Cochrane Database of Systematic Reviews, 2018

Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.