Waseem Javed - Academia.edu (original) (raw)

Papers by Waseem Javed

Research paper thumbnail of Effectiveness, Safety, and Tolerability of Esomeprazole and Domperidone in Gastroesophageal Reflux Disease

Pakistan Journal of Medical and Health Sciences, Aug 30, 2022

Research paper thumbnail of Dermatophytic infection over the tattoo: A case report

RGUHS journal of medical sciences, 2020

Research paper thumbnail of Olmsted Syndrome: a case report

RGUHS Journal of Medical Sciences

Olmsted syndrome is a rare keratinisation disorder characterised by mutilating palmoplantar kerat... more Olmsted syndrome is a rare keratinisation disorder characterised by mutilating palmoplantar keratoderma with peri-orificial hyperkeratosis. Till now around 73 cases have been reported. We are reporting a case of 3 year old female child with keratoderma of palms and soles since birth along with peri-orificial hyperkeratosis flexion deformity of digits of palms hypotrichosis and onychodystrophy. There was no history of hyperhidrosis no dental abnormalities and no sensorineural hearing loss. Hence the diagnosis of Olmsted syndrome was made.

Research paper thumbnail of Effectiveness, Safety, and Tolerability of Esomeprazole and Domperidone in Gastroesophageal Reflux Disease

Pakistan Journal of Medical and Health Sciences

Objective: The purpose of this study was to examine the clinical efficacy, tolerability, and safe... more Objective: The purpose of this study was to examine the clinical efficacy, tolerability, and safety of Esomeprazole 20 mg + sustained release (SR) Domperidone 30mg delivered once daily in adult patients for the symptomatic alleviation of dyspepsia associated with GERD. Study Design: Prospective Study Place and Duration: PIMS Hospital Islamabad. Dec 2021- May 2022 Methods: Total 97 patients of both genders had symptomatic dyspepsia associated with GERD were presented in this study. Patients were aged between 20-75 years. Informed written consent of all the patients were taken for detailed demographics. Patients were given a fixed-dose combination of Esomeprazole 20 mg and sustained-release (SR) Domperidone 30 mg once day for two weeks. Treatment efficacy was determined by whether or not patients' symptoms improved and whether or not they were happy with the care they received. Physical tests determined the level of safety and tolerability. SPSS 22.0 was used to analyze all data. ...

Research paper thumbnail of Keratotic Papules, Anserine Folliculosis

Research paper thumbnail of Examination in Semester System: What is Observation of Faculty and Students?

The examination is an organized system of evaluating and estimating students’ academic abilities ... more The examination is an organized system of evaluating and estimating students’ academic abilities and performance. It is a standardized procedure to measure quantitatively or qualitatively through verbal or non-verbal behaviors. It can also be defined as a means of measuring knowledge, skills, feelings, intelligence, or aptitude of an individual or a group. Both the annual and semester systems of examination are in practice simultaneously at university level in Pakistan. This paper is a case study that discusses the students and teachers’ perception toward the semester system of examination at university level in Pakistan. A small sample consisting of 270 students and 45 teachers of different departments of The Islamia University of Bahawalpur, Pakistan includes both the Bahawalnagar and Rahimyar Khan Campuses was taken from the representation of all the programs of the university. A 34-item questionnaire on 5-point Likret scale was administered to the students. Data was analyzed by ...

Research paper thumbnail of C-Reactive Protein Levels and the Severity of COVID-19

Pakistan Armed Forces Medical Journal, 2020

Objective: To compare the C-reactive protein levels in different groups of COVID-19 patients to a... more Objective: To compare the C-reactive protein levels in different groups of COVID-19 patients to assess disease severity Study Design: Cross sectional study Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun 2020 Methodology: Forty five Confirmed cases of COVID-19 patients were included by non-probability consecutive sampling Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical) Serum sample for C - reactive protein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test and one way Anova (Post Hoc LSD) Result: Out of 45 cases in our study 28 (62 2%) were male and 17 (37 8%) were female Mean age of patients was 51 96 ± 16 and mean C-reactive protein levels were 76 61 ± 75 mg/L When compared by paired sample t-test C-reactive protein levels were: higher in the mild patient group than asymptomatic group, higher in the moderate group than mild group, higher in severe g...

Research paper thumbnail of Clinical profile of patients with tinea versicolor

International Journal of Research in Dermatology, 2018

Background: Pityriasis versicolor is a superficial fungal infection caused by the polymorphous en... more Background: Pityriasis versicolor is a superficial fungal infection caused by the polymorphous endogenous yeast Malassezia furfur. Infection typically occurs on the trunk and proximal upper extremities and is characterized by distinctive scaly, coalescent hyperpigmented and/or hypopigmented to erythematous patches. Tinea versicolor is a superficial chronically recurring fungal infection of the stratum corneum, characterized by scaly, hypo and hyperpigmented irregular macules, usually located on the trunk and proximal extremities caused by pityrosporum orbiculare.Methods: 100 patients of untreated tinea versicolor who attended the outpatient department were selected at random irrespective of their age, socioeconomic status, occupation. A detailed history was taken, regarding the age, sex, religion, occupation, socioeconomic status, residence, duration and course of the disease, site of distribution of lesion and any other associated cutaneous and systemic diseases.Results: The majori...

Research paper thumbnail of SARS-CoV-2-Specific Antibody Detection in Healthcare Workers in a UK Maternity Hospital: Correlation With SARS-CoV-2 RT-PCR Results

Clinical Infectious Diseases, 2020

Research paper thumbnail of A comparative study of fractional carbon dioxide laser, narrowband ultraviolet B and topical tacrolimus 0.1% ointment versus narrowband ultraviolet B, topical tacrolimus 0.1% ointment in stable vitiligo

International Journal of Research in Dermatology, 2020

Background: Vitiligo, an acquired pigmentary disorder of skin and mucous membrane characterized b... more Background: Vitiligo, an acquired pigmentary disorder of skin and mucous membrane characterized by well circumscribed depigmented macules that occur secondary to selective destruction of melanocytes. Fractional CO2 laser system is a recent advancement in the treatment of vitiligo which works on the concept of fractional photo-thermolysis, in which microscopic treatment zones are created which help in increasing the penetration of topically applied agent which indirectly improves drug efficacy.Methods: A comparative study was conducted on 40 patients of stable vitiligo attending OPD, Dept of DVL with fractional CO2 laser, narrowband ultraviolet B (NBUVB) and topical tacrolimus 0.1% vs NBUVB, topical tacrolimus 0.1% for a duration of 4 months and patients were followed up for 12 weeks post treatment.Results: Patients on Fractional CO2 laser in combination with NBUVB and topical tacrolimus 0.1% ointment showed >50% improvement compared with other group, with duration for initiation ...

Research paper thumbnail of A clinical and epidemiological study of hyperpigmentary disorder of face

International Journal of Research in Dermatology, 2020

Background: Facial pigmentary disorders are a group of heterogenous entities, sharing a common cl... more Background: Facial pigmentary disorders are a group of heterogenous entities, sharing a common clinical feature of altered pigmentation of the face and thus easily visible cosmetic disfigurement. Although the increased melanin provides protection from harmful effects of UV radiation, including photodamage and skin cancers, it also makes darkly pigmented skin more vulnerable to post-inflammatory dyspigmentation. The importance of these disorders is growing, as they form the major percentage of dermatology consultations. The objective of the study was to assess the clinical profile of patients with facial hyperpigmentation.Methods: The present cross-sectional hospital based observational study was conducted at Dermatology Department of during the period of June 2017 to December 2017 including patients with diagnosis of facial hyperpigmentation. Data analysed with SPSS 24 version.Results: 29% were from 21 to 30 years age group followed by 25% from 31 to 40 years age group. Mean age of ...

Research paper thumbnail of Clinical profile of pityriasis rosea: a descriptive study from urban Karnataka

International Journal of Research in Dermatology, 2019

Background: Pityriasis rosea (PR) is common, self-limited papulo-squamous dermatosis of unknown o... more Background: Pityriasis rosea (PR) is common, self-limited papulo-squamous dermatosis of unknown origin, which mainly appears in adolescents and young adults (10-35 years). It has a sudden onset, and in its typical presentation, the eruption is proceeded by a solitary patch termed “herald patch”, mainly located on the trunk. The objective of the study was to assess the clinical profile of pityriasis rosea.Methods: The data was collected from patients attending the Department of Dermatology, Basaveshwar Teaching and General Hospital attached to Mahadevappa Rampure Medical College, Gulbarga. It is a descriptive observational study. A total 79 patients suffering from pityriasis rosea who attended the outpatient department were included in the present study during the period from 2006 to 2007.Results: Out of 79 patients studied, majority were from 11-20 years age group 33 (41.8%) followed by 27.8% from 21-30 years age group. The mean age of study population was found to be 21.3±6.4 years...

Research paper thumbnail of Keratotic Papules of Chin: A Case Series

Journal of Evidence Based Medicine and Healthcare, 2016

Keratotic papules of the chin is not frequently encountered in Dermatology practice. To date less... more Keratotic papules of the chin is not frequently encountered in Dermatology practice. To date less than 30 cases have been reported. 1 It occurs on the limited areas of skin receiving prolonged friction and/or pressure by other parts of patient's skin. It was first reported by Padilha-Goncalves in 1977 and named "Traumatic anserine folliculosis" for the stressing aetiologic factor i.e. friction or pressure, the goose skin appearance and follicular location of the lesions. 2 Mehta in 1988 described similar condition in 6 females. 3 Presently, we are presenting a case series of Anserine Folliculosis.

Research paper thumbnail of Keratotic Papules, Anserine Folliculosis

Research paper thumbnail of Clinico-epidemiological study of dermatophytosis in teaching hospital of North Karnataka

International Journal of Research in Dermatology, 2019

Worldwide it is found that fungal infections of the skin, hair, and nails due to dermatophytes ar... more Worldwide it is found that fungal infections of the skin, hair, and nails due to dermatophytes are common problem. Both sexes and all ages are susceptible to dermatophytoses. Amongst all, Tinea capitis is more common in prepubescent children whereas tinea cruris and tinea pedis are common in adult males. 1 Despite the fact that dermatophytosis takes place global, person dermatophyte species may additionally vary in their geographic distribution and self-virulence. Those problems cannot be differentiated by ethnicity or socioeconomic popularity; however poverty and overcrowded living conditions are important underlying social determinants. 2 Factors contributing to the high frequency and continual occurrences of dermatophytosis in developing nations may also consist of negative residing situations, kids interaction styles, and poor health looking for behavior. 3 Dermatophytes are fungal agents of dermatophytoses. Superficial mycoses of dermatophytoses are named after anatomic localization of the lesions. Dermatophytosis ABSTRACT Background: Although fungi are worldwide, only few of them are considered pathogenic. The pathogenic fungi may give rise to infections in animals and human beings. Skin infection due to dermatophytes has become a significant health problem of late equally affecting children, adolescents and adults. Depending on the climate and culture, the clinical picture can vary enormously. The objective of the study was to study the clinical and diagnostic spectrum of dermatophytosis at Dermatology OPD of KBNIMS, Kalaburagi. Methods: The present descriptive study was conducted in Dermatology OPD in teaching Hospital of North Karnataka. Results: Majority of the subjects were from 21 to 40 years age group i.e. 44.58% followed by 36.4% from 0 to 20 years age group. Out of 250 patients, majority were males i.e. 70.4% whereas 29.6% were females. More than half i.e. 174 (69.6%) out of 250 patients were KOH positive. Prevalence of culture positive specimen was found to be 40%. T. cruris (35%) and corporis (32%) were most common infections in our study. 31% of cases T. mentagrophyte was observed as most common isolate on culture.. Conclusions: In our study, most common dermatophytic infection was T. cruris (35%). Only 40% were culture positive and among which Trichophton mentagrophyte was commonly seen isolate. Low socioeconomic status, overcrowding and compromised personal hygiene with tropical climate are prevalent factors in our study.

Research paper thumbnail of Effectiveness, Safety, and Tolerability of Esomeprazole and Domperidone in Gastroesophageal Reflux Disease

Pakistan Journal of Medical and Health Sciences, Aug 30, 2022

Research paper thumbnail of Dermatophytic infection over the tattoo: A case report

RGUHS journal of medical sciences, 2020

Research paper thumbnail of Olmsted Syndrome: a case report

RGUHS Journal of Medical Sciences

Olmsted syndrome is a rare keratinisation disorder characterised by mutilating palmoplantar kerat... more Olmsted syndrome is a rare keratinisation disorder characterised by mutilating palmoplantar keratoderma with peri-orificial hyperkeratosis. Till now around 73 cases have been reported. We are reporting a case of 3 year old female child with keratoderma of palms and soles since birth along with peri-orificial hyperkeratosis flexion deformity of digits of palms hypotrichosis and onychodystrophy. There was no history of hyperhidrosis no dental abnormalities and no sensorineural hearing loss. Hence the diagnosis of Olmsted syndrome was made.

Research paper thumbnail of Effectiveness, Safety, and Tolerability of Esomeprazole and Domperidone in Gastroesophageal Reflux Disease

Pakistan Journal of Medical and Health Sciences

Objective: The purpose of this study was to examine the clinical efficacy, tolerability, and safe... more Objective: The purpose of this study was to examine the clinical efficacy, tolerability, and safety of Esomeprazole 20 mg + sustained release (SR) Domperidone 30mg delivered once daily in adult patients for the symptomatic alleviation of dyspepsia associated with GERD. Study Design: Prospective Study Place and Duration: PIMS Hospital Islamabad. Dec 2021- May 2022 Methods: Total 97 patients of both genders had symptomatic dyspepsia associated with GERD were presented in this study. Patients were aged between 20-75 years. Informed written consent of all the patients were taken for detailed demographics. Patients were given a fixed-dose combination of Esomeprazole 20 mg and sustained-release (SR) Domperidone 30 mg once day for two weeks. Treatment efficacy was determined by whether or not patients' symptoms improved and whether or not they were happy with the care they received. Physical tests determined the level of safety and tolerability. SPSS 22.0 was used to analyze all data. ...

Research paper thumbnail of Keratotic Papules, Anserine Folliculosis

Research paper thumbnail of Examination in Semester System: What is Observation of Faculty and Students?

The examination is an organized system of evaluating and estimating students’ academic abilities ... more The examination is an organized system of evaluating and estimating students’ academic abilities and performance. It is a standardized procedure to measure quantitatively or qualitatively through verbal or non-verbal behaviors. It can also be defined as a means of measuring knowledge, skills, feelings, intelligence, or aptitude of an individual or a group. Both the annual and semester systems of examination are in practice simultaneously at university level in Pakistan. This paper is a case study that discusses the students and teachers’ perception toward the semester system of examination at university level in Pakistan. A small sample consisting of 270 students and 45 teachers of different departments of The Islamia University of Bahawalpur, Pakistan includes both the Bahawalnagar and Rahimyar Khan Campuses was taken from the representation of all the programs of the university. A 34-item questionnaire on 5-point Likret scale was administered to the students. Data was analyzed by ...

Research paper thumbnail of C-Reactive Protein Levels and the Severity of COVID-19

Pakistan Armed Forces Medical Journal, 2020

Objective: To compare the C-reactive protein levels in different groups of COVID-19 patients to a... more Objective: To compare the C-reactive protein levels in different groups of COVID-19 patients to assess disease severity Study Design: Cross sectional study Place and Duration of Study: Combined Military Hospital Kohat, from Apr 2020 to Jun 2020 Methodology: Forty five Confirmed cases of COVID-19 patients were included by non-probability consecutive sampling Patients were divided into five groups (Asymptomatic, Mild, Moderate, Severe and Critical) Serum sample for C - reactive protein levels were collected at presentation and compared in different clinical groups by Paired sample “t” test and one way Anova (Post Hoc LSD) Result: Out of 45 cases in our study 28 (62 2%) were male and 17 (37 8%) were female Mean age of patients was 51 96 ± 16 and mean C-reactive protein levels were 76 61 ± 75 mg/L When compared by paired sample t-test C-reactive protein levels were: higher in the mild patient group than asymptomatic group, higher in the moderate group than mild group, higher in severe g...

Research paper thumbnail of Clinical profile of patients with tinea versicolor

International Journal of Research in Dermatology, 2018

Background: Pityriasis versicolor is a superficial fungal infection caused by the polymorphous en... more Background: Pityriasis versicolor is a superficial fungal infection caused by the polymorphous endogenous yeast Malassezia furfur. Infection typically occurs on the trunk and proximal upper extremities and is characterized by distinctive scaly, coalescent hyperpigmented and/or hypopigmented to erythematous patches. Tinea versicolor is a superficial chronically recurring fungal infection of the stratum corneum, characterized by scaly, hypo and hyperpigmented irregular macules, usually located on the trunk and proximal extremities caused by pityrosporum orbiculare.Methods: 100 patients of untreated tinea versicolor who attended the outpatient department were selected at random irrespective of their age, socioeconomic status, occupation. A detailed history was taken, regarding the age, sex, religion, occupation, socioeconomic status, residence, duration and course of the disease, site of distribution of lesion and any other associated cutaneous and systemic diseases.Results: The majori...

Research paper thumbnail of SARS-CoV-2-Specific Antibody Detection in Healthcare Workers in a UK Maternity Hospital: Correlation With SARS-CoV-2 RT-PCR Results

Clinical Infectious Diseases, 2020

Research paper thumbnail of A comparative study of fractional carbon dioxide laser, narrowband ultraviolet B and topical tacrolimus 0.1% ointment versus narrowband ultraviolet B, topical tacrolimus 0.1% ointment in stable vitiligo

International Journal of Research in Dermatology, 2020

Background: Vitiligo, an acquired pigmentary disorder of skin and mucous membrane characterized b... more Background: Vitiligo, an acquired pigmentary disorder of skin and mucous membrane characterized by well circumscribed depigmented macules that occur secondary to selective destruction of melanocytes. Fractional CO2 laser system is a recent advancement in the treatment of vitiligo which works on the concept of fractional photo-thermolysis, in which microscopic treatment zones are created which help in increasing the penetration of topically applied agent which indirectly improves drug efficacy.Methods: A comparative study was conducted on 40 patients of stable vitiligo attending OPD, Dept of DVL with fractional CO2 laser, narrowband ultraviolet B (NBUVB) and topical tacrolimus 0.1% vs NBUVB, topical tacrolimus 0.1% for a duration of 4 months and patients were followed up for 12 weeks post treatment.Results: Patients on Fractional CO2 laser in combination with NBUVB and topical tacrolimus 0.1% ointment showed >50% improvement compared with other group, with duration for initiation ...

Research paper thumbnail of A clinical and epidemiological study of hyperpigmentary disorder of face

International Journal of Research in Dermatology, 2020

Background: Facial pigmentary disorders are a group of heterogenous entities, sharing a common cl... more Background: Facial pigmentary disorders are a group of heterogenous entities, sharing a common clinical feature of altered pigmentation of the face and thus easily visible cosmetic disfigurement. Although the increased melanin provides protection from harmful effects of UV radiation, including photodamage and skin cancers, it also makes darkly pigmented skin more vulnerable to post-inflammatory dyspigmentation. The importance of these disorders is growing, as they form the major percentage of dermatology consultations. The objective of the study was to assess the clinical profile of patients with facial hyperpigmentation.Methods: The present cross-sectional hospital based observational study was conducted at Dermatology Department of during the period of June 2017 to December 2017 including patients with diagnosis of facial hyperpigmentation. Data analysed with SPSS 24 version.Results: 29% were from 21 to 30 years age group followed by 25% from 31 to 40 years age group. Mean age of ...

Research paper thumbnail of Clinical profile of pityriasis rosea: a descriptive study from urban Karnataka

International Journal of Research in Dermatology, 2019

Background: Pityriasis rosea (PR) is common, self-limited papulo-squamous dermatosis of unknown o... more Background: Pityriasis rosea (PR) is common, self-limited papulo-squamous dermatosis of unknown origin, which mainly appears in adolescents and young adults (10-35 years). It has a sudden onset, and in its typical presentation, the eruption is proceeded by a solitary patch termed “herald patch”, mainly located on the trunk. The objective of the study was to assess the clinical profile of pityriasis rosea.Methods: The data was collected from patients attending the Department of Dermatology, Basaveshwar Teaching and General Hospital attached to Mahadevappa Rampure Medical College, Gulbarga. It is a descriptive observational study. A total 79 patients suffering from pityriasis rosea who attended the outpatient department were included in the present study during the period from 2006 to 2007.Results: Out of 79 patients studied, majority were from 11-20 years age group 33 (41.8%) followed by 27.8% from 21-30 years age group. The mean age of study population was found to be 21.3±6.4 years...

Research paper thumbnail of Keratotic Papules of Chin: A Case Series

Journal of Evidence Based Medicine and Healthcare, 2016

Keratotic papules of the chin is not frequently encountered in Dermatology practice. To date less... more Keratotic papules of the chin is not frequently encountered in Dermatology practice. To date less than 30 cases have been reported. 1 It occurs on the limited areas of skin receiving prolonged friction and/or pressure by other parts of patient's skin. It was first reported by Padilha-Goncalves in 1977 and named "Traumatic anserine folliculosis" for the stressing aetiologic factor i.e. friction or pressure, the goose skin appearance and follicular location of the lesions. 2 Mehta in 1988 described similar condition in 6 females. 3 Presently, we are presenting a case series of Anserine Folliculosis.

Research paper thumbnail of Keratotic Papules, Anserine Folliculosis

Research paper thumbnail of Clinico-epidemiological study of dermatophytosis in teaching hospital of North Karnataka

International Journal of Research in Dermatology, 2019

Worldwide it is found that fungal infections of the skin, hair, and nails due to dermatophytes ar... more Worldwide it is found that fungal infections of the skin, hair, and nails due to dermatophytes are common problem. Both sexes and all ages are susceptible to dermatophytoses. Amongst all, Tinea capitis is more common in prepubescent children whereas tinea cruris and tinea pedis are common in adult males. 1 Despite the fact that dermatophytosis takes place global, person dermatophyte species may additionally vary in their geographic distribution and self-virulence. Those problems cannot be differentiated by ethnicity or socioeconomic popularity; however poverty and overcrowded living conditions are important underlying social determinants. 2 Factors contributing to the high frequency and continual occurrences of dermatophytosis in developing nations may also consist of negative residing situations, kids interaction styles, and poor health looking for behavior. 3 Dermatophytes are fungal agents of dermatophytoses. Superficial mycoses of dermatophytoses are named after anatomic localization of the lesions. Dermatophytosis ABSTRACT Background: Although fungi are worldwide, only few of them are considered pathogenic. The pathogenic fungi may give rise to infections in animals and human beings. Skin infection due to dermatophytes has become a significant health problem of late equally affecting children, adolescents and adults. Depending on the climate and culture, the clinical picture can vary enormously. The objective of the study was to study the clinical and diagnostic spectrum of dermatophytosis at Dermatology OPD of KBNIMS, Kalaburagi. Methods: The present descriptive study was conducted in Dermatology OPD in teaching Hospital of North Karnataka. Results: Majority of the subjects were from 21 to 40 years age group i.e. 44.58% followed by 36.4% from 0 to 20 years age group. Out of 250 patients, majority were males i.e. 70.4% whereas 29.6% were females. More than half i.e. 174 (69.6%) out of 250 patients were KOH positive. Prevalence of culture positive specimen was found to be 40%. T. cruris (35%) and corporis (32%) were most common infections in our study. 31% of cases T. mentagrophyte was observed as most common isolate on culture.. Conclusions: In our study, most common dermatophytic infection was T. cruris (35%). Only 40% were culture positive and among which Trichophton mentagrophyte was commonly seen isolate. Low socioeconomic status, overcrowding and compromised personal hygiene with tropical climate are prevalent factors in our study.