Wasim Memon - Academia.edu (original) (raw)

Papers by Wasim Memon

Authorea (Authorea), Apr 5, 2023

Inflammatory pseudo tumor is an entity of pancreatic carcinoma composed of inflammatory cells and... more Inflammatory pseudo tumor is an entity of pancreatic carcinoma composed of inflammatory cells and myofibroblastic spindle cells. In our novel case series, we report four such cases of pancreatic pseudo tumors with patients ranging from 30 to 70 years of age.

PubMed, Feb 1, 2001

Objective: To evaluate the efficacy of magnetic resonance imaging (MRI) for distinguishing tuberc... more Objective: To evaluate the efficacy of magnetic resonance imaging (MRI) for distinguishing tuberculosis from other types of meningoencephalitis. Patients and methods: MRIs of 100 patients with tuberculous (50), pyogenic (33), viral (14), or fungal (3) meningoencephalitis were analyzed independently by 2 radiologists. Number, size, location, signal characteristics, surrounding edema, and contrast enhancement pattern of nodular lesions; location and pattern of meningeal enhancement; extent of infarct or encephalitis and hydrocephalus were evaluated. Results: Contrast-enhancing nodular lesions were detected in patients with tuberculous (43 of 50 patients), pyogenic (9 of 33), and fungal (3 of 3) infections. No nodules were detected in patients with viral meningoencephalitis. Using the criteria of 1 or more solid rim or homogeneously enhancing nodules smaller than 2 cm, the sensitivity, specificity and accuracy for diagnosing tuberculous meningitis were 86.0%, 90.0% and 88.0%, respectively. Conclusion: Magnetic resonance imaging is useful in distinguishing tuberculous from pyogenic, viral and fungal meningoencephalitis.

The American Journal of Gastroenterology, Jul 1, 2016

A previously healthy 58-year-old woman presented with tender, pink papules and plaques over the p... more A previously healthy 58-year-old woman presented with tender, pink papules and plaques over the palms (a) and soles, episcleritis, ankle edema, and bloody stools. She was afebrile, with a normal abdominal exam, and lab tests showed an elevated leukocyte count (13,300/μl), erythrocyte sedimentation rate (56 mm/h), and C-reactive protein (29.3 mg/L). Colonoscopy identified ulcerations in the rectosigmoid and sigmoid colon (b), and the biopsy revealed active colitis and crypt distortion (c; hematoxylin and eosin (H&E) ×10), consistent with ulcerative colitis. Palmar punch biopsy demonstrated nodular and diffuse neutrophilic infiltrate in the midto upper dermis (d; H&E ×10), consistent with neutrophilic dermatosis. Among the many extraintestinal manifestations of inflammatory bowel disease, palmoplantar neutrophilic dermatosis is a rare cutaneous complication.

Cureus, Aug 5, 2019

Introduction Differences between appendicoliths associated with appendicitis and those found inci... more Introduction Differences between appendicoliths associated with appendicitis and those found incidentally have not been studied. The objective of this study was to determine the characteristics of appendicoliths that are associated with acute appendicitis. Methods A cross-sectional study of patients with appendicoliths identified on computed tomographic (CT) scan from January 2008 till December 2014 was conducted. Patients were divided into two group: appendicitis and appendicoliths (AA) and incidentally discovered appendicoliths (IA). Results Overall, 321 patients were included in the study. Of these, 103 (32%) patients were in the AA group while 218 (68%) patients were in the IA group. Both groups were similar in age and gender distribution. Significantly greater proportion of patients in the AA group had more than one appendicolith [AA vs. IA: 63 (62%) vs. 82 (38%), p < 0.001], appendicolith location at the base [AA vs. IA: 34 (33%) vs. 33 (15%), p < 0.001] and appendicolith diameter of 5 mm or more [AA vs. IA: 71 (69%) vs. 28 (13%), p < 0.001]. On multivariate analysis, more than one appendicolith [Odds ratio (OR): 1.9, 95% CI: 1.1-3.4; p = 0.02] and diameter of 5 mm or more (OR: 13, 95% CI: 7.1-23.6; p < 0.001) were independently associated with acute appendicitis. Conclusion Multiple appendicoliths and appendicoliths larger than 5 mm are associated with acute appendicitis.

Journal of Ultrasound in Medicine, Jul 1, 2011

onography is a relatively safe, feasible, and quick diagnostic procedure and is considered the se... more onography is a relatively safe, feasible, and quick diagnostic procedure and is considered the second most commonly used diagnostic imaging modality. 1 It is most extensively applied for evaluation of the fetus and generally perceived as safe in prenatal diagnosis. To date, no harmful effects from ultrasound on humans have been reported, 2 but ultrasound bioeffects have been observed in animal models by using similar acoustic outputs that are used in humans. 3-19 Ultrasound can generate cavitation in tissues in the presence of gaseous bubbles, and the relative probability of its occurrence can be estimated by the mechanical index 20 of an ultrasound beam. Ultrasound contrast agents are commonly composed of microbubbles, and the use of these contrast agents may aggravate ultrasound-induced cavitation in human tissue. The collapse of ultrasound-induced cavitation may produce local heating and high pressure. The thermal index indicates the potential of an

Cases Journal, Dec 1, 2008

Introduction: Chemotherapy Induced neutropenia is a frequent and serious complication of cytotoxi... more Introduction: Chemotherapy Induced neutropenia is a frequent and serious complication of cytotoxic cancer treatment. Granulocyte colony stimulating factors (G-CSF) are frequently used to counter neutropenia, attempt rapid recovery of patients and allow for continuation of treatment without compromise on dose, especially in curative malignancies. Generally regarded as safe, G-CSF use has been very rarely reported to have resulted in serious side effects, such as, splenic rupture. Case presentation: We are reporting a case of a twenty years old man, who was being treated for T cell acute lymphoblastic leukemia and received colony stimulating factors for treatment of severe neutropenia and suffered from splenic rupture, He was treated with splenectomy. Conclusion: Although extremely rare, splenic rupture can be a serious and sometimes life threatening complication of high dose colony stimulating factors therapy.

Journal of Pakistan Medical Association, Jun 15, 2023

, and comprised patients of either gender aged <18 years who received cochlear implants. All subj... more , and comprised patients of either gender aged <18 years who received cochlear implants. All subjects underwent computed tomography and magnetic resonance imaging of the temporal bone to identify any inner ear anomaly. The data gathered included implantation age, gender, computed tomography and magnetic resonance imaging findings, and history of congenital anomaly, neurodevelopmental disorder, family hearing loss, consanguinity and brain-evoked response auditory result. Data was analysed using SPSS 23. Results: Of the 120 patients, 66(55%) were females and 54(45%) were males. The median age of the patients was 3 years (interquartile range: 2-5 years). Of the total, 7(5.8%) patients presented with inner ear malformations; 3(2.5%) each with enlarged vestibular aqueduct, Mondini malformation type II, and 1(0.8%) with semi-circular canal dysplasia. Conclusion: The frequency of inner ear anomalies amongst cochlear implant candidates was 5.8%, and the most common anomalies were enlarged vestibular aqueduct and Mondini malformation type II.

Radiology Case Reports, Mar 1, 2023

The American Journal of Gastroenterology, Oct 1, 2020

Journal of Medical Case Reports, Nov 10, 2017

Background: Intrahepatic biliary cystadenomas are rare hepatic neoplasms, which are usually cysti... more Background: Intrahepatic biliary cystadenomas are rare hepatic neoplasms, which are usually cystic. These tumors are often misdiagnosed as simple liver cysts and hydatid cysts clinically and radiologically owing to nonspecific clinical and radiologic features. These tumors require complete resection, as recurrence and malignant transformation can occur following incomplete excision. It is essential that these tumors be diagnosed accurately so that they can be adequately excised. Methods: Clinical and radiological features of six cases of biliary cystadenoma are described. Results: All of these cases were resected with the clinical and/or radiological impression of simple liver cysts and/ or hydatid cysts. Out of the six patients, five were female and one was male. Ages of the patients ranged from 28 to 60 years (mean 45 years). The patients presented with nonspecific symptoms. Internal septations were seen on preoperative imaging (when available). On gross examination, all tumors were cystic; their sizes varied from 5.5 to 14 cm, mean size was 9.0 cm. On histopathologic examination, cystic spaces were lined by cuboidal to columnar mucin-secreting epithelium with underlying ovarian-type stroma. In one case, ovarian-type stroma was not seen. Recurrence was seen in three cases at 1 to 5 years of follow up. Conclusions: Owing to their malignant potential and high recurrence rate following incomplete resection, an aggressive surgical approach is recommended. Prognosis is excellent after complete resection.

Neurology India, 2017

Background: Papillary craniopharyngioma (PCP) are uncommon variants of craniopharyngiomas (CP), w... more Background: Papillary craniopharyngioma (PCP) are uncommon variants of craniopharyngiomas (CP), which are benign epithelial neoplasms of the sellar and suprasellar region. Histologically, PCPs are typically composed of well-differentiated stratified squamous epithelium; however, focal variations are not uncommon. A distinction from other lesions of the region, despite being difficult to achieve due to the overlapping radiological and clinical features, is important for adequate treatment to be administered. Objective: Our aim was to study the clinical and histological features of PCP with emphasis on features that are helpful in its distinction from other lesions that are similar in appearance. Materials and Methods: We reviewed 13 cases of PCP diagnosed in our institution between January 2010 and December 2015. Results: The mean age at presentation was 30.76 years. Two of the patients belonged to the pediatric age group. Male-to-female ratio was 2.25:1. Suprasellar location (either alone or in combination with sellar region) was the most common tumor site. Microscopically, all of the cases showed stratified squamous epithelium with frequent pseudopapillae formation. Focal adamantinomatous epithelium and columnar epithelium with variable cilia and goblet cells were seen in 4 (30.7%) cases. Brain invasion was observed in 3 (23%) cases. Four patients died of their disease; 2 of the 7 patients with an available follow up, developed recurrences; and, 5 experienced severe postoperative morbidity. Conclusion: Majority of the PCPs exhibited typical features with minor variations. Knowledge of the variations in histologic features helps in reaching the correct diagnosis. These tumors can behave aggressively with a high recurrence rate and decreased overall survival.

Seminars in Ultrasound Ct and Mri, Feb 1, 2005

The role of un enhanced helical CT (UHCT) in the evaluation of acute flank pain suggestive of uri... more The role of un enhanced helical CT (UHCT) in the evaluation of acute flank pain suggestive of urinary tract calculi is increasingly appreciated in the last few years. Recent studies have identified the advantages of UHCT in recognizing alternative findings within or outside the urinary tract. These incidental diagnoses on UHCT alter a patient&amp;amp;amp;amp;amp;amp;amp;#39;s management and demonstrate the pivotal role of UHCT in rapidly triaging these patients for appropriate management. Clinical impact of incidental diagnoses is maximal in identifying alternate emergent conditions mimicking reno-ureteric colic and in identifying malignancies at an early stage when they are potentially curable.

PubMed, Jul 18, 2017

Mesenteric vasculitis and resultant bowel ischemia is rare but serious complication of autoimmune... more Mesenteric vasculitis and resultant bowel ischemia is rare but serious complication of autoimmune disorders. Early detection and treatment is the key to avoid potentially fatal outcomes of bowel perforation and peritonitis. In this series, we present patients presenting with acute abdominal pain and having CT imaging features of bowel ischemia who responded well to immunosuppressive therapy. The aim of this work is to familiarize health professionals with possibility and imaging features of mesenteric vasculitis.

PubMed, Jun 7, 2017

Isolated tuberculosis of upper gastrointestinal tract is a rare pathology, often mimicking malign... more Isolated tuberculosis of upper gastrointestinal tract is a rare pathology, often mimicking malignancy in clinical presentation and radiological features. We present a case of middle aged gentleman with isolated tuberculosis of stomach, proven on histopathology and showing remarkable improvement on follow up.

Clinical Neuropathology, 2015

Japanese Journal of Radiology, Dec 16, 2011

Intussusception is the most common abdominal emergency in early childhood, but it is rare entity ... more Intussusception is the most common abdominal emergency in early childhood, but it is rare entity in adults. Jejenoduodenogastric intussusception is an exceedingly rare retrograde small-bowel intussusception. Percutaneous endoscopic gastrostomy (PEG) has become the preferred procedure for establishing enteral feeding in most clinical situations. Despite the fact that it is relatively safe, a number of complications can occur following PEG placement; jejenoduodenogastric intussusception is one of them, but it is a very rare entity. Here, we report a case of jejenoduodenogastric intussusception secondary to placement of a PEG tube in an adult patient. To our knowledge, this is the third case of isolated duodenogastric intussusception being reported.

World Journal of Gastrointestinal Surgery, Sep 27, 2019

Author contributions: Khan MS provided the case details, figures, and wrote the case details; Maa... more Author contributions: Khan MS provided the case details, figures, and wrote the case details; Maan MHA did the literature review and wrote the case details and discussion; Sohail AH wrote the introduction and discussion; Memon WA was involved in writing the discussion and final editing of the manuscript.

Japanese Journal of Radiology, Dec 14, 2011

ABSTRACT To determine the accuracy of 64-slice multidetector computed tomography scans in detecti... more ABSTRACT To determine the accuracy of 64-slice multidetector computed tomography scans in detecting the point of transition of small bowel obstruction by using surgical findings as the gold standard. Cross-sectional study of 59 patients with SBO who underwent 64-slice MDCT scans of the abdomen followed by surgery from 1 June 2008 to 31 January 2010 at a tertiary care center. Point of transition between distended and collapsed small bowel loops were precisely determined on 64-slice MDCT and subsequently correlated with surgical findings. Data analysis was done on SPSS version 16. Sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy of MDCT in detection of the point of transition were calculated. Out of 59 patients, 64-slice MDCT was able to detect the point of transition of SBO in 90% (53/59) of patients, while in 10% (6/59) of these patients the point of transition was not found on MDCT. Overall for detection of the point of transition of small bowel obstruction 64-slice MDCT has 93% sensitivity, 67% specificity, 98% positive predictive value, 33% negative predictive value and 92% accuracy, respectively. Sixty-four-slice MDCT is highly accurate in diagnosing the point of transition of small bowel obstruction with an accuracy of 92%. It can be used as a localizing tool before surgery for small bowel obstruction.

International Journal of General Medicine, Dec 1, 2011

Cureus, Jun 10, 2019

Cholecystocolonic fistula (CCF) is a rare complication of gallstone disease with a variable clini... more Cholecystocolonic fistula (CCF) is a rare complication of gallstone disease with a variable clinical presentation. It is difficult to diagnose CCF pre-operatively despite modern diagnostic and imaging modalities as they are often asymptomatic or incidentally discovered, often perioperatively. However, management of this uncommon yet important finding is not very well described in the literature. The most common fistula is the cholecystoduodenal fistula, followed by the cholecystocolonic fistula; the cholecystogastric fistula is reportedly the least commonly reported. We report our experience with three cases of cholecystocolonic fistula discovered on imaging which were subsequently confirmed through surgery.