Wil Dan - Academia.edu (original) (raw)
Papers by Wil Dan
Universitat de Barcelona, Nov 26, 2020
Finally, we present the fabrication of a muscle-based bio-robot able to swim by inertial strokes ... more Finally, we present the fabrication of a muscle-based bio-robot able to swim by inertial strokes in a liquid interface and a nanocomposite-laden bio-robot that can crawl on a surface. The first biorobot is thoroughly characterized through mechanical simulations, allowing us to optimize the skeleton, based on a serpentine or spring-like structure. Moreover, we compare the motion of symmetric and asymmetric designs, demonstrating that, although symmetric bio-robots can achieve some motion due to spontaneous symmetry breaking during its self-assembly, asymmetric bio-robots are faster and more consistent in their directionality. The nanocomposite-laden crawling bio-robot consisted of embedded piezoelectric boron nitride nanotubes that improved the differentiation of the muscle tissue due to a feedback loop of piezoelectric effect activated by the same spontaneous contractions of the tissue. We find that bio-robots with those nanocomposites achieve faster motion and stronger force outputs, demonstrating the beneficial effects in their differentiation. This research presented in this thesis contributes to the development of the field of bio-hybrid robotic devices. On enzymatically propelled nano-and micromotors, the novel theoretical framework and the results regarding the interaction of nanomotors with complex media might offer useful fundamental knowledge for future biomedical applications of these systems. The bioengineering approaches developed to fabricate murine-or human-based bio-actuators might find applications in drug screening or to model heterogeneous muscle diseases in biomedicine using the patient's own cells. Finally, the fabrication of bio-hybrid swimmers and nanocomposite crawlers will help understand and improve the swimming motion of these devices, as well as pave the way towards the use of nanocomposite to enhance the performance of future actuators. Para concluir, estos resultados ofrecen varias ventajas en el campo de los bio-robots híbridos. Sobre nano-y micromotores propulsados enzimáticamente, el marco teórico desarrollado y los resultados obtenidos sobre su interacción con fluidos complejos podría proporcionar conocimiento fundamental y útil para próximas aplicaciones biomédicas. Los métodos de bioingeniería desarrollados para la fabricación de músculo esquelético en forma de bio-actuadores con células de ratón o humanas podrían encontrar aplicaciones en detección y testeo de drogas o para modelar enfermedades musculares usando las células de los propios pacientes. Finalmente, la fabricación de los bio-robots capaces de nadar o con nanocompuestos ayudará a entender y mejorar el movimiento de natación de estos robots, así como allanar el camino para el uso de nanocompuestos como método de mejorar la actuación de futuros actuadores híbridos.
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist), 2019
Menurut WHO kejadian anemia kehamilan berkisar 20% sampai 89% dengan menetapkan hemoglobin 11gram... more Menurut WHO kejadian anemia kehamilan berkisar 20% sampai 89% dengan menetapkan hemoglobin 11gram/% sebagai dasarnya. Hemoglobin kurang dari 11 gram/% pada wanita hamil dapat menimbulkandampak mulai saat dalam kandungan, setelah lahir menimbulkan masalah bagi bayi, seperti berat badan lahirrendah, penurunan status imun, kemungkinan gangguan fisiologis, dan tumbuh kembang bayi. Jenispenelitian ini bersifat analitik dengan desain penelitian cross sectional. Populasi dan sampel dari penelitianini adalah ibu hamil sebanyak 58 orang dengan teknik accidental sampling,dengan menggunakan uji Chi-Square. Ibu berpengetahuan kurang sebanyak 22 orang (37,93%). Responden tidak patuh mayoritas padaumur 20-35 tahun sebanyak 22 orang (56,5%), ibu yang berpendidikan SMP sebanyak 12 orang (66,67%),kehamilan secundipara sebanyak 12 orang (63,15%). Hasil uji Chi-Square menyatakan ada hubunganpengetahuan dengan kepatuhan meminum tablet zat besi (x2 = 15,07), ada hubungan umur dengan kepatuhanmeminum tab...
Universitat de Barcelona, Nov 26, 2020
Finally, we present the fabrication of a muscle-based bio-robot able to swim by inertial strokes ... more Finally, we present the fabrication of a muscle-based bio-robot able to swim by inertial strokes in a liquid interface and a nanocomposite-laden bio-robot that can crawl on a surface. The first biorobot is thoroughly characterized through mechanical simulations, allowing us to optimize the skeleton, based on a serpentine or spring-like structure. Moreover, we compare the motion of symmetric and asymmetric designs, demonstrating that, although symmetric bio-robots can achieve some motion due to spontaneous symmetry breaking during its self-assembly, asymmetric bio-robots are faster and more consistent in their directionality. The nanocomposite-laden crawling bio-robot consisted of embedded piezoelectric boron nitride nanotubes that improved the differentiation of the muscle tissue due to a feedback loop of piezoelectric effect activated by the same spontaneous contractions of the tissue. We find that bio-robots with those nanocomposites achieve faster motion and stronger force outputs, demonstrating the beneficial effects in their differentiation. This research presented in this thesis contributes to the development of the field of bio-hybrid robotic devices. On enzymatically propelled nano-and micromotors, the novel theoretical framework and the results regarding the interaction of nanomotors with complex media might offer useful fundamental knowledge for future biomedical applications of these systems. The bioengineering approaches developed to fabricate murine-or human-based bio-actuators might find applications in drug screening or to model heterogeneous muscle diseases in biomedicine using the patient's own cells. Finally, the fabrication of bio-hybrid swimmers and nanocomposite crawlers will help understand and improve the swimming motion of these devices, as well as pave the way towards the use of nanocomposite to enhance the performance of future actuators. Para concluir, estos resultados ofrecen varias ventajas en el campo de los bio-robots híbridos. Sobre nano-y micromotores propulsados enzimáticamente, el marco teórico desarrollado y los resultados obtenidos sobre su interacción con fluidos complejos podría proporcionar conocimiento fundamental y útil para próximas aplicaciones biomédicas. Los métodos de bioingeniería desarrollados para la fabricación de músculo esquelético en forma de bio-actuadores con células de ratón o humanas podrían encontrar aplicaciones en detección y testeo de drogas o para modelar enfermedades musculares usando las células de los propios pacientes. Finalmente, la fabricación de los bio-robots capaces de nadar o con nanocompuestos ayudará a entender y mejorar el movimiento de natación de estos robots, así como allanar el camino para el uso de nanocompuestos como método de mejorar la actuación de futuros actuadores híbridos.
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist), 2019
Menurut WHO kejadian anemia kehamilan berkisar 20% sampai 89% dengan menetapkan hemoglobin 11gram... more Menurut WHO kejadian anemia kehamilan berkisar 20% sampai 89% dengan menetapkan hemoglobin 11gram/% sebagai dasarnya. Hemoglobin kurang dari 11 gram/% pada wanita hamil dapat menimbulkandampak mulai saat dalam kandungan, setelah lahir menimbulkan masalah bagi bayi, seperti berat badan lahirrendah, penurunan status imun, kemungkinan gangguan fisiologis, dan tumbuh kembang bayi. Jenispenelitian ini bersifat analitik dengan desain penelitian cross sectional. Populasi dan sampel dari penelitianini adalah ibu hamil sebanyak 58 orang dengan teknik accidental sampling,dengan menggunakan uji Chi-Square. Ibu berpengetahuan kurang sebanyak 22 orang (37,93%). Responden tidak patuh mayoritas padaumur 20-35 tahun sebanyak 22 orang (56,5%), ibu yang berpendidikan SMP sebanyak 12 orang (66,67%),kehamilan secundipara sebanyak 12 orang (63,15%). Hasil uji Chi-Square menyatakan ada hubunganpengetahuan dengan kepatuhan meminum tablet zat besi (x2 = 15,07), ada hubungan umur dengan kepatuhanmeminum tab...