William Murphy - Academia.edu (original) (raw)
Address: Fargo, United States
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PennState Hershey (Milton S. Hershey Medical Center)
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Papers by William Murphy
Journal of the American College of Cardiology, 2006
The full text is published on the ACC and AHA World Wide Web sites. Copies of the full text and t... more The full text is published on the ACC and AHA World Wide Web sites. Copies of the full text and the executive summary are available from both organizations.
Annals of Thoracic Surgery, 1984
Prophylactic administration of platelet concentrates to patients undergoing their first cardiopul... more Prophylactic administration of platelet concentrates to patients undergoing their first cardiopulmonary bypass operation (coronary artery bypass grafting or uncomplicated valve replacement) was evaluated in a controlled randomized study of 28 patients. Four units of platelet concentrates administered at the end of bypass prevented prolongation of the bleeding time seen in patients not receiving platelets. However, chest tube blood loss, transfusion requirements, and clinical outcome were not improved. Moreover, thrombocytopenia and pmlongation of bleeding time did not correlate with blood loss or transfusion needs. Mild thmmbocytopenia (to 58,000 platelets per microliter) and transient platelet dysfunction after bypass do not require administration of platelet concentrates, and prophylactic use of this blood component in the surgical setting of bypass is not indicated.
Journal of the American College of Cardiology, 2006
The full text is published on the ACC and AHA World Wide Web sites. Copies of the full text and t... more The full text is published on the ACC and AHA World Wide Web sites. Copies of the full text and the executive summary are available from both organizations.
Annals of Thoracic Surgery, 1984
Prophylactic administration of platelet concentrates to patients undergoing their first cardiopul... more Prophylactic administration of platelet concentrates to patients undergoing their first cardiopulmonary bypass operation (coronary artery bypass grafting or uncomplicated valve replacement) was evaluated in a controlled randomized study of 28 patients. Four units of platelet concentrates administered at the end of bypass prevented prolongation of the bleeding time seen in patients not receiving platelets. However, chest tube blood loss, transfusion requirements, and clinical outcome were not improved. Moreover, thrombocytopenia and pmlongation of bleeding time did not correlate with blood loss or transfusion needs. Mild thmmbocytopenia (to 58,000 platelets per microliter) and transient platelet dysfunction after bypass do not require administration of platelet concentrates, and prophylactic use of this blood component in the surgical setting of bypass is not indicated.