William Seitz - Academia.edu (original) (raw)
Papers by William Seitz
BMC Musculoskeletal Disorders
Previous studies have shown radioulnar wrist compression augments carpal arch space. This study i... more Previous studies have shown radioulnar wrist compression augments carpal arch space. This study investigated the effects of radioulnar wrist compression on patient-reported outcomes associated with carpal tunnel syndrome. Subjects underwent thrice-daily (15 min each time 45 min daily) wrist compression over 4 weeks with an additional four weeks of follow-up without treatment. Primary outcomes included Boston Carpal Tunnel Questionnaire symptom and functional severity scales (SSS and FSS) and symptoms of numbness/tingling based on Visual Analog Scales. Our results showed that radioulnar wrist compression improved SSS by 0.55 points after 2 weeks (p < 0.001) and 0.51 points at 4 weeks (p < 0.006) compared to the baseline scale. At the four-week follow-up, SSS remined improved at 0.47 points (p < 0.05). Symptoms of numbness/tingling improved at two and 4 weeks, as well as the follow-up (p < 0.05). Hand motor impairment such as weakness had a lower frequency across carpal tu...
The American Journal of Sports Medicine, 2019
Background: Shoulder pain and dysfunction are common indications for rotator cuff repair surgery,... more Background: Shoulder pain and dysfunction are common indications for rotator cuff repair surgery, yet the factors that are associated with these symptoms are not fully understood. Purpose/Hypothesis: This study aimed to investigate the associations of patient and disease-specific factors with baseline patient-reported outcome measures (PROMs) in patients undergoing rotator cuff repair. We hypothesized that tear size and mental health status, as assessed by the Veterans RAND 12-Item Health Survey mental component score (VR-12 MCS), would be associated with baseline total Penn Shoulder Score (PSS) and its pain, function, and satisfaction subscale scores. Study Design: Cross-sectional study; Level of evidence, 3. Methods: We prospectively identified 12 patient factors and 12 disease-specific factors as possible statistical predictors for baseline PROMs in patients undergoing surgical repair of superior-posterior rotator cuff tears at a single institution over a 3-year period. Multivari...
Journal of medical and biological engineering, 2017
Carpal tunnel syndrome (CTS), caused by entrapment of the median nerve in the carpal tunnel, impa... more Carpal tunnel syndrome (CTS), caused by entrapment of the median nerve in the carpal tunnel, impairs hand function including dexterous manipulation. The purpose of this study was to investigate the effects of CTS on force coordination and muscle coherence during low-intensity sustained precision pinch while the wrist assumed different postures. Twenty subjects (10 CTS patients and 10 asymptomatic controls) participated in this study. An instrumented pinch device was used to measure the thumb and index finger forces while simultaneously collecting surface electromyographic activities of the abductor pollicis brevis (APB) and first dorsal interosseous (FDI) muscles. Subjects performed a sustained precision pinch at 10% maximum pinch force for 15 sec with the wrist stabilized at 30° extension, neutral, or 30° flexion using customized splints. The force discrepancy and the force coordination angle between the thumb and index finger forces were calculated, as well as the β-band (15-30 Hz...
HAND, 2018
Background: Total wrist arthroplasty (TWA) is indicated to alleviate pain secondary to arthritis ... more Background: Total wrist arthroplasty (TWA) is indicated to alleviate pain secondary to arthritis while preserving wrist motion. Despite vigilant measures, TWAs are susceptible to complications. The current case illustrates an array of preventable complications which are addressed through operative technique in a revision setting. Case presentation: The patient was a 72-year-old man who presented with chronic pain at the fourth carpometacarpal joint (CMCJ) and distal radioulnar joint with paresthesias in the median nerve distribution. Surgery was undertaken to address the following complications secondary to a previous TWA: impingement of the native distal ulna on the prosthesis, carpal tunnel due to metallosis and polyethylene synovitis, loose carpal component, and prominent screw at the fourth CMCJ. Surgical correction included open carpal tunnel release with extensive flexor tenosynovectomy, distal ulna resection and implant arthroplasty with shortening, revision of carpal compone...
The Journal of Hand Surgery, Mar 1, 1990
In an effort to reduce treatment-related complications, a surgical procedure has been developed f... more In an effort to reduce treatment-related complications, a surgical procedure has been developed for the insertion and application of an external fixation device in the management of unstable fractures of the distal radius. Clinical experience with this device has demonstrated its effectiveness in reducing complications associated with pin insertion. The surgical technique is presented together with a case example. Results of laboratory tests corroborate our clinical experience and demonstrate the effectiveness of this technique in minimizing complications. Clinical results in 66 cases document the efficacy and safety of this technique. (J HAND SURC 1990;15A:288-93.
Orthopedics, Apr 1, 1987
Maintenance of length, alignment, and mobility while affording ready access for wound care has tr... more Maintenance of length, alignment, and mobility while affording ready access for wound care has traditionally been a problem in the management of severe hand trauma. However, miniaturization of existing components of external fixation has provided a significant step in the solution of this problem. Twenty-eight fractures in severely traumatized hands in 24 patients have been managed using a Hoffman mini external fixateur. The patients' mean age was 26.5 years. The dominant hand was involved 60% of the time, and 80% of the population was male. Most fractures (80%) were open injuries with marked comminution, often intra-articular, frequently the result of gunshot wounds (60%). Mini external fixation has afforded proper wound care and maintenance of desired alignment. Complications have been few, while improved results (alignment, range of motion, strength, fracture union), have been demonstrated. Our surgical technique, results, and some illustrative cases are presented.
American Journal of Cardiology, Dec 1, 2021
Cardiac amyloidosis is often preceded by orthopedic manifestations such as carpal tunnel syndrome... more Cardiac amyloidosis is often preceded by orthopedic manifestations such as carpal tunnel syndrome, and 10% of patients who underwent idiopathic carpal tunnel release surgery will have biopsy-confirmed amyloid deposits in the tenosynovial sheath. Trigger finger is also commonly reported in patients with amyloidosis and involves the same tendon sheath as carpal tunnel syndrome, but the prevalence of amyloid deposition is unclear. This prospective cross-sectional study enrolled 100 patients aged ≥50 years at the time of surgery for idiopathic trigger finger. Patients underwent release surgery, and a sample of the tenosynovium of the affected finger was excised, stained with Congo red, and subtyped with mass spectrometry if amyloid was demonstrated. Further cardiac evaluation was performed in patients with amyloid deposition. Of the 100 patients (mean age 65.5 ± 8.1 years) enrolled, only 2 demonstrated amyloid deposits on Congo red staining. One patient with previous proteinuric kidney disease had fibrinogen A α-chain amyloidosis, and the other patient had untyped amyloidosis. Neither patient had cardiac involvement. A total of 13 of the 100 patients underwent concomitant carpal tunnel release surgery, and 2 of these patients had amyloid deposits in the carpal tunnel with "false-negative" samples from the trigger finger tenosynovium. In conclusion, biopsy during trigger finger release surgery demonstrated a 2% yield for amyloidosis, which is significantly lower than the previously published yield of 10% during carpal tunnel release surgery. This observation has important implications for the development of diagnostic algorithms to screen patients for amyloidosis during orthopedic operations.
The American Journal of Cardiology
The Journal of Hand Surgery, 1990
In an effort to reduce treatment-related complications, a surgical procedure has been developed f... more In an effort to reduce treatment-related complications, a surgical procedure has been developed for the insertion and application of an external fixation device in the management of unstable fractures of the distal radius. Clinical experience with this device has demonstrated its effectiveness in reducing complications associated with pin insertion. The surgical technique is presented together with a case example. Results of laboratory tests corroborate our clinical experience and demonstrate the effectiveness of this technique in minimizing complications. Clinical results in 66 cases document the efficacy and safety of this technique. (J HAND SURC 1990;15A:288-93.
Journal of Pediatric Orthopaedics, Jul 1, 1985
Seminars in Arthroplasty, 2012
Achieving sufficient exposure of the glenoid is one of the most demanding aspects of shoulder art... more Achieving sufficient exposure of the glenoid is one of the most demanding aspects of shoulder arthroplasty surgery. Beginning with the positioning of patient and ending with the final placement and adjustment of retractors, multiple maneuvers must be taken at each step of the procedure to ultimately allow for adequate glenoid visualization. With thoughtful planning, patience, and attention to detail, the glenoid can be reliably and reproducibly exposed to allow for a successful reconstruction. This article outlines the key technical steps and pearls for successful glenoid exposure.
The American Journal of Cardiology
Journal of the American College of Cardiology, Jan 23, 2018
Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifes... more Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years. However, the prevalence of cardiac involvement at the time of carpal tunnel surgery has not been established. The authors sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement. The authors also sought to determine if patients with soft tissue transthyretin (TTR) amyloid had abnormal TTR tetramer kinetic stability. This was a prospective, cross-sectional, multidisciplinary study of consecutive men age ≥50 years and women ≥60 years undergoing carpal tunnel release surgery. Biopsy specimens of tenosynovial tissue were obtained and stained with Congo red; those with confirmed amyloid deposits were typed with mass spectrometry and further evaluated for cardiac involvement with biomarkers, electrocardiography, echocardiography with longitudinal strain, and technetium pyrophospha...
Current Opinion in Orthopaedics
ABSTRACT
Current Opinion in Orthopaedics
ABSTRACT
The Journal of Hand Surgery
Journal of Musculoskeletal Research
The purpose of this study was to investigate the morphological and mechanical properties of the t... more The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.
Journal of Cardiac Failure
Hypokalemia results from increased activation of Renin Angiotensin Aldosterone System. Low serum ... more Hypokalemia results from increased activation of Renin Angiotensin Aldosterone System. Low serum potassium increases the transmembrane resting potential of myocardial cells resulting in hyperpolarization and increased excitability. This increases risk of cardiac arrhythmias. Ventricular arrhythmias are the most common cause of death in these patients. Thus, normokalemia and hyperkalemia in patients admitted with CHF has a beneficial effect. This can be achieved by use of potassium supplements, ACE inhibitors and K-sparing diuretics. Whether correction of hypokalemia during hospital stay is beneficial or not is a matter of further studies.
J Shoulder Elbow Surg, 1996
Clinical Orthopaedics and Related Research, Apr 1, 1991
Ulnar nerve decompression with medial epicondylectomy was performed in 66 elbows between 1966 and... more Ulnar nerve decompression with medial epicondylectomy was performed in 66 elbows between 1966 and 1986 for compressive ulnar neuropathy at the elbow. This study is an updated review that adds 36 cases to a previously published report on 30 cases. These elbows were graded preoperatively and postoperatively using McGowan's grading system. Eighty-three percent improved one or two grades, and 11% improved subjectively although they showed no objective improvement, 3% noted no change, and 3% were subjectively worse. One early case sustained damage to the ulnar collateral ligament with resultant instability. No other complications occurred. The best results were seen in the Grade I and II lesions, whereas those with Grade III lesions were the least predictable. The procedure is technically uncomplicated with minimal morbidity and reliable results.
BMC Musculoskeletal Disorders
Previous studies have shown radioulnar wrist compression augments carpal arch space. This study i... more Previous studies have shown radioulnar wrist compression augments carpal arch space. This study investigated the effects of radioulnar wrist compression on patient-reported outcomes associated with carpal tunnel syndrome. Subjects underwent thrice-daily (15 min each time 45 min daily) wrist compression over 4 weeks with an additional four weeks of follow-up without treatment. Primary outcomes included Boston Carpal Tunnel Questionnaire symptom and functional severity scales (SSS and FSS) and symptoms of numbness/tingling based on Visual Analog Scales. Our results showed that radioulnar wrist compression improved SSS by 0.55 points after 2 weeks (p < 0.001) and 0.51 points at 4 weeks (p < 0.006) compared to the baseline scale. At the four-week follow-up, SSS remined improved at 0.47 points (p < 0.05). Symptoms of numbness/tingling improved at two and 4 weeks, as well as the follow-up (p < 0.05). Hand motor impairment such as weakness had a lower frequency across carpal tu...
The American Journal of Sports Medicine, 2019
Background: Shoulder pain and dysfunction are common indications for rotator cuff repair surgery,... more Background: Shoulder pain and dysfunction are common indications for rotator cuff repair surgery, yet the factors that are associated with these symptoms are not fully understood. Purpose/Hypothesis: This study aimed to investigate the associations of patient and disease-specific factors with baseline patient-reported outcome measures (PROMs) in patients undergoing rotator cuff repair. We hypothesized that tear size and mental health status, as assessed by the Veterans RAND 12-Item Health Survey mental component score (VR-12 MCS), would be associated with baseline total Penn Shoulder Score (PSS) and its pain, function, and satisfaction subscale scores. Study Design: Cross-sectional study; Level of evidence, 3. Methods: We prospectively identified 12 patient factors and 12 disease-specific factors as possible statistical predictors for baseline PROMs in patients undergoing surgical repair of superior-posterior rotator cuff tears at a single institution over a 3-year period. Multivari...
Journal of medical and biological engineering, 2017
Carpal tunnel syndrome (CTS), caused by entrapment of the median nerve in the carpal tunnel, impa... more Carpal tunnel syndrome (CTS), caused by entrapment of the median nerve in the carpal tunnel, impairs hand function including dexterous manipulation. The purpose of this study was to investigate the effects of CTS on force coordination and muscle coherence during low-intensity sustained precision pinch while the wrist assumed different postures. Twenty subjects (10 CTS patients and 10 asymptomatic controls) participated in this study. An instrumented pinch device was used to measure the thumb and index finger forces while simultaneously collecting surface electromyographic activities of the abductor pollicis brevis (APB) and first dorsal interosseous (FDI) muscles. Subjects performed a sustained precision pinch at 10% maximum pinch force for 15 sec with the wrist stabilized at 30° extension, neutral, or 30° flexion using customized splints. The force discrepancy and the force coordination angle between the thumb and index finger forces were calculated, as well as the β-band (15-30 Hz...
HAND, 2018
Background: Total wrist arthroplasty (TWA) is indicated to alleviate pain secondary to arthritis ... more Background: Total wrist arthroplasty (TWA) is indicated to alleviate pain secondary to arthritis while preserving wrist motion. Despite vigilant measures, TWAs are susceptible to complications. The current case illustrates an array of preventable complications which are addressed through operative technique in a revision setting. Case presentation: The patient was a 72-year-old man who presented with chronic pain at the fourth carpometacarpal joint (CMCJ) and distal radioulnar joint with paresthesias in the median nerve distribution. Surgery was undertaken to address the following complications secondary to a previous TWA: impingement of the native distal ulna on the prosthesis, carpal tunnel due to metallosis and polyethylene synovitis, loose carpal component, and prominent screw at the fourth CMCJ. Surgical correction included open carpal tunnel release with extensive flexor tenosynovectomy, distal ulna resection and implant arthroplasty with shortening, revision of carpal compone...
The Journal of Hand Surgery, Mar 1, 1990
In an effort to reduce treatment-related complications, a surgical procedure has been developed f... more In an effort to reduce treatment-related complications, a surgical procedure has been developed for the insertion and application of an external fixation device in the management of unstable fractures of the distal radius. Clinical experience with this device has demonstrated its effectiveness in reducing complications associated with pin insertion. The surgical technique is presented together with a case example. Results of laboratory tests corroborate our clinical experience and demonstrate the effectiveness of this technique in minimizing complications. Clinical results in 66 cases document the efficacy and safety of this technique. (J HAND SURC 1990;15A:288-93.
Orthopedics, Apr 1, 1987
Maintenance of length, alignment, and mobility while affording ready access for wound care has tr... more Maintenance of length, alignment, and mobility while affording ready access for wound care has traditionally been a problem in the management of severe hand trauma. However, miniaturization of existing components of external fixation has provided a significant step in the solution of this problem. Twenty-eight fractures in severely traumatized hands in 24 patients have been managed using a Hoffman mini external fixateur. The patients' mean age was 26.5 years. The dominant hand was involved 60% of the time, and 80% of the population was male. Most fractures (80%) were open injuries with marked comminution, often intra-articular, frequently the result of gunshot wounds (60%). Mini external fixation has afforded proper wound care and maintenance of desired alignment. Complications have been few, while improved results (alignment, range of motion, strength, fracture union), have been demonstrated. Our surgical technique, results, and some illustrative cases are presented.
American Journal of Cardiology, Dec 1, 2021
Cardiac amyloidosis is often preceded by orthopedic manifestations such as carpal tunnel syndrome... more Cardiac amyloidosis is often preceded by orthopedic manifestations such as carpal tunnel syndrome, and 10% of patients who underwent idiopathic carpal tunnel release surgery will have biopsy-confirmed amyloid deposits in the tenosynovial sheath. Trigger finger is also commonly reported in patients with amyloidosis and involves the same tendon sheath as carpal tunnel syndrome, but the prevalence of amyloid deposition is unclear. This prospective cross-sectional study enrolled 100 patients aged ≥50 years at the time of surgery for idiopathic trigger finger. Patients underwent release surgery, and a sample of the tenosynovium of the affected finger was excised, stained with Congo red, and subtyped with mass spectrometry if amyloid was demonstrated. Further cardiac evaluation was performed in patients with amyloid deposition. Of the 100 patients (mean age 65.5 ± 8.1 years) enrolled, only 2 demonstrated amyloid deposits on Congo red staining. One patient with previous proteinuric kidney disease had fibrinogen A α-chain amyloidosis, and the other patient had untyped amyloidosis. Neither patient had cardiac involvement. A total of 13 of the 100 patients underwent concomitant carpal tunnel release surgery, and 2 of these patients had amyloid deposits in the carpal tunnel with "false-negative" samples from the trigger finger tenosynovium. In conclusion, biopsy during trigger finger release surgery demonstrated a 2% yield for amyloidosis, which is significantly lower than the previously published yield of 10% during carpal tunnel release surgery. This observation has important implications for the development of diagnostic algorithms to screen patients for amyloidosis during orthopedic operations.
The American Journal of Cardiology
The Journal of Hand Surgery, 1990
In an effort to reduce treatment-related complications, a surgical procedure has been developed f... more In an effort to reduce treatment-related complications, a surgical procedure has been developed for the insertion and application of an external fixation device in the management of unstable fractures of the distal radius. Clinical experience with this device has demonstrated its effectiveness in reducing complications associated with pin insertion. The surgical technique is presented together with a case example. Results of laboratory tests corroborate our clinical experience and demonstrate the effectiveness of this technique in minimizing complications. Clinical results in 66 cases document the efficacy and safety of this technique. (J HAND SURC 1990;15A:288-93.
Journal of Pediatric Orthopaedics, Jul 1, 1985
Seminars in Arthroplasty, 2012
Achieving sufficient exposure of the glenoid is one of the most demanding aspects of shoulder art... more Achieving sufficient exposure of the glenoid is one of the most demanding aspects of shoulder arthroplasty surgery. Beginning with the positioning of patient and ending with the final placement and adjustment of retractors, multiple maneuvers must be taken at each step of the procedure to ultimately allow for adequate glenoid visualization. With thoughtful planning, patience, and attention to detail, the glenoid can be reliably and reproducibly exposed to allow for a successful reconstruction. This article outlines the key technical steps and pearls for successful glenoid exposure.
The American Journal of Cardiology
Journal of the American College of Cardiology, Jan 23, 2018
Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifes... more Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years. However, the prevalence of cardiac involvement at the time of carpal tunnel surgery has not been established. The authors sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement. The authors also sought to determine if patients with soft tissue transthyretin (TTR) amyloid had abnormal TTR tetramer kinetic stability. This was a prospective, cross-sectional, multidisciplinary study of consecutive men age ≥50 years and women ≥60 years undergoing carpal tunnel release surgery. Biopsy specimens of tenosynovial tissue were obtained and stained with Congo red; those with confirmed amyloid deposits were typed with mass spectrometry and further evaluated for cardiac involvement with biomarkers, electrocardiography, echocardiography with longitudinal strain, and technetium pyrophospha...
Current Opinion in Orthopaedics
ABSTRACT
Current Opinion in Orthopaedics
ABSTRACT
The Journal of Hand Surgery
Journal of Musculoskeletal Research
The purpose of this study was to investigate the morphological and mechanical properties of the t... more The purpose of this study was to investigate the morphological and mechanical properties of the transverse carpal ligament (TCL) in patients with carpal tunnel syndrome (CTS). Thickness and stiffness of the TCL in eight female CTS patients and eight female control subjects were examined using ultrasound imaging modalities. CTS patients had a 30.9% thicker TCL than control subjects. There was no overall difference in TCL stiffness between the two groups, but the radial TCL region was significantly stiffer than the ulnar region within the CTS group and such a regional difference was not found for the controls. The increased thickness and localized stiffness of the TCL for CTS patients may contribute to CTS symptoms due to reduction in carpal tunnel space and compliance. Advancements in ultrasound technology provide a means of understanding CTS mechanisms and quantifying the morphological and mechanical properties of the TCL in vivo.
Journal of Cardiac Failure
Hypokalemia results from increased activation of Renin Angiotensin Aldosterone System. Low serum ... more Hypokalemia results from increased activation of Renin Angiotensin Aldosterone System. Low serum potassium increases the transmembrane resting potential of myocardial cells resulting in hyperpolarization and increased excitability. This increases risk of cardiac arrhythmias. Ventricular arrhythmias are the most common cause of death in these patients. Thus, normokalemia and hyperkalemia in patients admitted with CHF has a beneficial effect. This can be achieved by use of potassium supplements, ACE inhibitors and K-sparing diuretics. Whether correction of hypokalemia during hospital stay is beneficial or not is a matter of further studies.
J Shoulder Elbow Surg, 1996
Clinical Orthopaedics and Related Research, Apr 1, 1991
Ulnar nerve decompression with medial epicondylectomy was performed in 66 elbows between 1966 and... more Ulnar nerve decompression with medial epicondylectomy was performed in 66 elbows between 1966 and 1986 for compressive ulnar neuropathy at the elbow. This study is an updated review that adds 36 cases to a previously published report on 30 cases. These elbows were graded preoperatively and postoperatively using McGowan's grading system. Eighty-three percent improved one or two grades, and 11% improved subjectively although they showed no objective improvement, 3% noted no change, and 3% were subjectively worse. One early case sustained damage to the ulnar collateral ligament with resultant instability. No other complications occurred. The best results were seen in the Grade I and II lesions, whereas those with Grade III lesions were the least predictable. The procedure is technically uncomplicated with minimal morbidity and reliable results.