Xin Yang - Academia.edu (original) (raw)

Papers by Xin Yang

Langmuir : the ACS journal of surfaces and colloids, Jan 13, 2015

Wax deposition is a detrimental problem that happens during crude oil production and transportati... more Wax deposition is a detrimental problem that happens during crude oil production and transportation, which greatly reduces transport efficiency and causes huge economic losses. To avoid wax deposition, a bioinspired composite coating with excellent wax prevention and anticorrosion properties is developed in this study. The prepared coating is composed of three films, including an electrodeposited Zn film for improving corrosion resistance, a phosphating film for constructing fish-scale morphology, and a silicon dioxide film modified by a simple spin-coating method for endowing the surface with superhydrophilicity. Good wax prevention performance has been investigated in a wax deposition test. The surface morphology, composition, wetting behaviors, and stability are systematically studied, and a wax prevention mechanism is proposed, which can be calculated from water film theory. This composite coating strategy which shows excellent properties in both wax prevention and stability is ...

Clinical Lung Cancer, 2015

Estimation of the survival of patients with lung squamous cell carcinoma (SCC) on the basis of hi... more Estimation of the survival of patients with lung squamous cell carcinoma (SCC) on the basis of histopathology is inadequate. The aim of this study was to identify genomic regions with potential value for estimating the prognosis of these patients. Depending on their survival time, 100 patients with primary lung SCC were separated into high- or low-risk prognostic groups, and their copy number aberrations (CNAs) were analyzed using array-comparative genomic hybridization (array-CGH). We identified 123 CNA regions that were significantly associated with survival. Among these regions, some have been reported previously (eg, amplifications of 8p12, 3q27.1, and loss of 9p21.3 and 13q34) but others have never been reported. For example, gains of 3q27.1, 5p13.2, and 5p13.3 were found to be associated with a favorable prognosis, but patients harboring gains of 11q23.3, 11q13.1, and 14q32.3, and deletions of 3p21.3 and 9p21.3 tended to have poor survival. Among the 123 CNA regions, 41 were further selected to construct a survival estimation model that could effectively separate SCC patients into high- or low-risk groups with an accuracy of 92%, sensitivity of 90%, and specificity of 94%. The results of the array-CGH were further validated in an independent cohort of 45 formalin-fixed, paraffin-embedded specimens using real-time polymerase chain reaction. A number of CNA regions were found to be associated with the survival of SCC patients, and we were able to construct a model to estimate prognosis on the basis of these regions. Assessment of these CNAs could potentially assist in clinical decision-making regarding adjuvant therapy after surgery.

Environmental science & technology, Jan 3, 2015

N-nitrosodimethylamine (NDMA) is an emerging disinfection by-product, and we show that use of chl... more N-nitrosodimethylamine (NDMA) is an emerging disinfection by-product, and we show that use of chlorine dioxide (ClO2) has the potential to increase NDMA formation in waters containing precursors with hydrazine moieties. NDMA formation was measured after oxidation of 13 amines by monochloramine, ClO2 and pre-treatment with ClO2 followed by post-monochloramination. Daminozide, a plant growth regulator, was found to yield 5.01±0.96% NDMA upon reaction with ClO2, although no NDMA was recorded during chloramination. The reaction rate was estimated to be ~0.0085 s-1 and based upon our identification by mass spectrometry spectra of intermediates the reaction likely proceeds via the hydrolytic release of unsymmetrical dimethylhydrazine (UDMH), with the hydrazine structure a key intermediate in NDMA formation. The presence of UDMH was confirmed by gas chromatography-mass spectrometry (GC-MS) analysis. For 10 of the 13 compounds, ClO2 pre-oxidation reduced NDMA yields compared with monochlora...

The journal of physical chemistry. A, Jan 24, 2015

Heterogeneous reactions of NO2 on various mineral aerosol particles have been investigated in man... more Heterogeneous reactions of NO2 on various mineral aerosol particles have been investigated in many previous studies, but a fundamental understanding of how the adsorption of formaldehyde influences the heterogeneous reactions of NO2 remains unclear. In this work, the effect of formaldehyde preadsorption on heterogeneous reaction of NO2 on the surface of γ-Al2O3 at 298 K and ambient pressure was investigated by using diffuse reflectance infrared Fourier transform spectrometry (DRIFTS). It was found that the preadsorption of HCHO on γ-Al2O3 could suppress the formation of nitrate, and the rate of nitrate formation decreased with increasing amount of preadsorbed HCHO, whereas the following heterogeneous uptake of NO2 could suppress the hydration reaction of HCHO and promote the production of HCOO(-) during the reaction. Surface nitrite was formed and identified to be an intermediate product and gradually disappeared as the reaction proceeded. The amount of the formed nitrite decreased ...

Langmuir : the ACS journal of surfaces and colloids, 2015

Recent interests in printable electronics and in particular paper and textile-based electronics h... more Recent interests in printable electronics and in particular paper and textile-based electronics have fueled research in inkjet printing of colloidal drops on porous substrates. On nonporous substrates, the interplay of particle motion and solvent evaporation determines the final deposition morphology of the evaporating colloidal drop. For porous substrates, solvent infiltration into the pores adds a layer of complexity to the deposition patterns that have not been fully elucidated in the literature. In this study, the deposition of picoliter-sized aqueous colloidal droplets containing nano- and micron-sized particles onto nanoporous anodic aluminum oxide substrates is examined for different drop and particle sizes, relative humidities, as well as pore diameters, porosities, and wettabilities of the porous substrates. For the cases considered, solvent infiltration is found to be much faster than both evaporation and particle motion near the contact line, and thus when the substrate f...

Environmental technology, Jan 16, 2015

Ciprofloxacin (CIP) is a commonly used antibiotic and widely detected in wastewaters and farmland... more Ciprofloxacin (CIP) is a commonly used antibiotic and widely detected in wastewaters and farmlands nowadays. This study evaluated the efficacy of next-generation adsorbent (graphene) and conventional adsorbent (granular activated carbon, GAC) for CIP removal. Batch experiments and characterization tests were conducted to investigate the adsorption kinetics, equilibrium isotherms, thermodynamic properties, and the influences of solution chemistry (pH, ionic strength, natural organic matter (NOM), and water sources). Compared to GAC, graphene showed significantly faster adsorption and reached equilibrium within 3 min, confirming the rapid access of CIP into the macroporous network of high surface area of graphene as revealed by the Brunner-Emmet-Teller measurements analysis. The kinetics was better described by a pseudo-second-order model, suggesting the importance of the initial CIP concentration related to surface site availability of graphene. The adsorption isotherm on graphene fo...

Journal of hazardous materials, Jan 9, 2015

This study investigated the effect of disinfection by-products (DBPs) formation in pre-oxidation ... more This study investigated the effect of disinfection by-products (DBPs) formation in pre-oxidation with ferrate(VI) (Fe(VI)O4(2-), Fe(VI)) and relationship between subsequent chlorination of Suwannee river natural organic matter (SRNOM) and eight model compounds containing moieties of alcohol, aldehyde, amines, amino acids, and phenol. The DBPs studied were trihalomethanes (THMs), chloral hydrate (CH), haloacetonitriles (HANs), and trichloronitromethane (TCNM). When the interaction of Fe(VI) and SRNOM was independently examined at pH 7.0, a decrease was seen in dissolved organic carbon and in the hydrophobic and hydrophilic fractions of NOM. With the model compounds, the results showed that Fe(VI) pre-oxidation and subsequent chlorination decreased the formation of THMs with most of the compounds except amines and glycine. The effect of Fe(VI) preoxidation on CH and HANs formation from model compounds varied and was dependent on ferrate doses. Fe(VI) pre-oxidation significantly enhanc...

Virus research, Jan 19, 2015

Infectious bronchitis virus (IBV) is a highly variable virus with a large number of genotypes. Du... more Infectious bronchitis virus (IBV) is a highly variable virus with a large number of genotypes. During 2011-2012, nineteen wild IBV strains were isolated in China. Sequence analysis showed that these isolates were divided into five sub-clusters: A2-like, CKCHLDL08I-like, SAIBK-like, KM91-like and TW97/4-like. Phylogenetic analysis based on the 1118 sequences available on line suggested that all IBVs were classified into six clusters. The prevalent strains including all the isolates were in cluster VI with a 0.194-0.259 genetic distance to Mass type vaccines. In addition, we introduced the smoothing spline clustering (SSC) method to estimate the highly variable sites for some sub-clusters. The results showed that highly variable sites range from sub-clusters, the N-terminal sequences of 4/91-Like, TW97/4-Like and Arkansas-like are more variable than other sub-clusters. This is the first time that the SSC method has been used for the evolution study of IBV.

The Science of the total environment, 2012

The effects of co-exposure to ultraviolet (UV) irradiation (with either low- or medium-pressure U... more The effects of co-exposure to ultraviolet (UV) irradiation (with either low- or medium-pressure UV lamps) and free chlorine (chloramine) at practical relevant conditions on changes in natural organic matter (NOM) properties were investigated using four waters. The changes were characterized using the specific disinfection by-product formation potential (SDBPFP), specific total organic halogen formation potential (STOXFP), differential UV absorbance (∆UVA), and size-exclusion chromatography (SEC). The results for exposure to UV irradiation alone and for samples with no exposure were also obtained. The SDBPFPs in all UV-irradiated NOM waters observed were higher than those of non-irradiated samples. UV irradiation led to increases in STOXFPs as a result of chlorination, but no changes, or only small decreases, from chloramination. UV irradiation alone led to positive ∆UVA spectra of the four NOM waters; co-exposure to UV and chlorine gave larger negative ∆UVA spectra than those obtain...

Journal of Medical Imaging and Health Informatics, 2015

ABSTRACT

Water research, 2005

Membrane introduction mass spectrometry (MIMS) was developed and verified for the direct quantifi... more Membrane introduction mass spectrometry (MIMS) was developed and verified for the direct quantification of cyanogen chloride (CNCl) and cyanogen bromide (CNBr) in environmental samples without any sample workup. Factors including the membrane temperature and the liquid flow rates were examined for system optimization. The MIMS method provided linear responses for three orders of magnitude of concentrations. The instrument detection limits of CNCl and CNBr were 1.2 and 3.8 microg/L, respectively, and the method detection limits of CNCl and CNBr were both 1.7 microg/L. Effects of pH and the water matrix including synthetic water, saline water, natural surface water, and wastewater, on the responses were also examined. A pH ranging from 3 to 10 did not affect the quantification. The average recoveries of CNCl and CNBr in the water matrixes tested were 98.5% and 92.7%, respectively. The use of the MIMS method in on-line monitoring of the formation of cyanogen halide was demonstrated in ...

European journal of obstetrics, gynecology, and reproductive biology, Jan 31, 2015

To evaluate the efficacy of the sonographic cardiothoracic ratio (CTR) in early pregnancy for the... more To evaluate the efficacy of the sonographic cardiothoracic ratio (CTR) in early pregnancy for the prediction of fetal haemoglobin (Hb) Bart's disease. Over a 1.5-year period at a Chinese tertiary obstetric centre, women at risk of Hb Bart's disease were given the option of a non-invasive approach to exclude an affected pregnancy between 11 weeks and 13 weeks and 6 days of gestation, with a routine rescan after a 2-week interval. The fetal CTR, a sonographic marker, was assessed, and invasive testing followed in cases of fetal cardiomegaly. The diagnosis of fetal Hb Bart's disease was based on DNA analysis from chorionic villus sampling. Of 154 at-risk cases studied, five cases (four at 11 weeks of gestation) were subjected to direct invasive testing because of an unsatisfactory scan. Of the remaining 149 cases, non-invasive ultrasound examinations were performed successfully. Thirty-four (22.8%) affected pregnancies were revealed, including one picked up on rescan. The s...

Biotechnology letters, Jan 14, 2015

To develop a cost-effective ELISA for detection of antibodies against infectious bronchitis virus... more To develop a cost-effective ELISA for detection of antibodies against infectious bronchitis virus (IBV) by using a multi-fragment protein as coating antigen. A multi-fragment antigen, termed BE, which was composed of eight antigenic fragments selected from the three major proteins (S, M, and N) of IBV, was expressed in Escherichia coli. The entire protein had a molecular weight of 61.5 kDa. In addition to it, a smaller truncated protein was also produced; both could react with IBV-positive serum. Next, an indirect ELISA (BE-ELISA) was developed. Coefficients of variation of this assay were lower than 10 %, and no cross-reactivity between the coated antigen BE and antiserum against newcastle disease virus, avian influenza virus, or infectious bursal disease virus was observed. The performance of BE-ELISA was evaluated, and showed 95.4 % coincidence ratio with the whole virus based-ELISA (IDEXX). The multi-fragment antigen (BE) may represent a promising alternative to the whole virus ...

European journal of orthodontics, Jan 25, 2015

To systematically investigate review in literature the effects of the Herbst appliance for patien... more To systematically investigate review in literature the effects of the Herbst appliance for patients with Class II malocclusion patients. We performed a comprehensive literature survey on PubMed, Web of Science, Embase, CENTRAL, SIGLE, and ClinicalTrial.gov up to December 2014. The selection criteria: randomized controlled trials or clinical controlled trials; using any kind of Herbst appliances to correct Class II division 1 malocclusions; skeletal and/or dental changes evaluated through lateral cephalograms. And the exclusion criteria: syndromic patients; individual case reports and series of cases; surgical interventions. Article screening, data extraction, assessment of risk of bias, and evaluation of evidence quality through GRADE were conducted independently by two well-trained orthodontic doctors. Consensus was made via group discussion of all authors when there is inconsistent information from the two. After that, sensitivity analysis and subgroup analysis were performed to e...

Chinese Journal of Oceanology and Limnology, 2010

The water and sediment discharge regulation (WSDR) project, which has been performed since 2002 b... more The water and sediment discharge regulation (WSDR) project, which has been performed since 2002 before flood season every year, is of great significance to the river management in China. Until 2007, six experiments have been fulfilled to evaluate the effect of the project on the natural environment. To fill the gap of investigations, a study on flood and suspended sediment

Journal of biomedical optics, 2015

Cerenkov luminescence tomography (CLT) is a promising tool that enables three-dimensional noninva... more Cerenkov luminescence tomography (CLT) is a promising tool that enables three-dimensional noninvasive in vivo detection of radiopharmaceuticals. Conventionally, multispectral information and diffusion theory were introduced to achieve whole-body tomographic reconstruction. However, the diffusion theory inevitably causes systematic error in blue bands of the electromagnetic spectrum due to high-tissue absorption, and CL has a blue-weighted broad spectrum. Therefore, it is challenging to improve the accuracy of CLT. The performance of the n -order simplified spherical harmonics approximation (SPn) in different spectra is evaluated, and a multispectral hybrid CLT based on the combination of different SPn models is proposed to handle the Cerenkov photon transport problem in complex media. The in vivo xenograft experiment shows that this approach can effectively improve the quality and accuracy of the reconstructed light source. We believe that the new reconstruction method will advance ...

Journal of hazardous materials, Jan 21, 2015

The effects of low-concentration monorhamnolipid (monoRL) on the adsorption of Pseudomonas aerugi... more The effects of low-concentration monorhamnolipid (monoRL) on the adsorption of Pseudomonas aeruginosa ATCC 9027 grown on glucose or hexadecane to glass beads with hydrophobic or hydrophilic surfaces was investigated using batch adsorption experiments. Results showed that adsorption isotherms of the cells on both types of glass beads fitted the Freundlich equation better than the Langmuir equation. The Kf of the Freundlich equation for adsorption of hexadecane-grown cell to glass beads with hydrophobic surface was remarkably higher than that for adsorption of hexadecane-grown cell to glass beads with hydrophilic surface, or glucose-grown cell to glass beads with either hydrophilic or hydrophobic surface. Furthermore, it decreased with the increasing monoRL concentration. For both groups of cells, the zeta potential was close to each other and stable with the increase of monoRL concentration. The surface hydrophobicity of hexadecane-grown cells, however, was significantly higher than ...