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Research paper thumbnail of Miniaturized electromechanical devices for the characterization of the biomechanics of deep tissue

Nature Biomedical Engineering, 2021

Note that full information on the approval of the study protocol must also be provided in the man... more Note that full information on the approval of the study protocol must also be provided in the manuscript. Clinical data Policy information about clinical studies All manuscripts should comply with the ICMJE guidelines for publication of clinical research and a completed CONSORT checklist must be included with all submissions. Clinical trial registration The research protocol was registered on ClinicalTrials.gov (Registration Number: NCT03461549). Study protocol The full trial protocol can be accessed at https://clinicaltrials.gov/ct2/show/NCT03461549. Data collection The sensors were mounted onto the relevant skin areas. The placement of the sensors was carried out by research staff and/or medical doctors. The EMM sensors were pre-connected to a DAQ system (including a locking-in amplifier and a current source) located within the operational room. Data recording began after 10 s of system warm-up, to ensure stable operation. Each subject performed 1-min measurement in a resting position. Data were collected and stored for further data analysis on a tablet computer. Outcomes Primary outcome measure: measurement results based on modulus sensor. Secondary outcome measures: Visual analogue scale of skin irritation.

Research paper thumbnail of Miniaturized electromechanical devices for the characterization of the biomechanics of deep tissue

Nature Biomedical Engineering, 2021

Note that full information on the approval of the study protocol must also be provided in the man... more Note that full information on the approval of the study protocol must also be provided in the manuscript. Clinical data Policy information about clinical studies All manuscripts should comply with the ICMJE guidelines for publication of clinical research and a completed CONSORT checklist must be included with all submissions. Clinical trial registration The research protocol was registered on ClinicalTrials.gov (Registration Number: NCT03461549). Study protocol The full trial protocol can be accessed at https://clinicaltrials.gov/ct2/show/NCT03461549. Data collection The sensors were mounted onto the relevant skin areas. The placement of the sensors was carried out by research staff and/or medical doctors. The EMM sensors were pre-connected to a DAQ system (including a locking-in amplifier and a current source) located within the operational room. Data recording began after 10 s of system warm-up, to ensure stable operation. Each subject performed 1-min measurement in a resting position. Data were collected and stored for further data analysis on a tablet computer. Outcomes Primary outcome measure: measurement results based on modulus sensor. Secondary outcome measures: Visual analogue scale of skin irritation.

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