Yeliz Çiftçi - Academia.edu (original) (raw)
Papers by Yeliz Çiftçi
Journal of the Neurological Sciences, 2013
Background: Recurrent stroke is defined as a new cerebrovascular event which occurs after the sta... more Background: Recurrent stroke is defined as a new cerebrovascular event which occurs after the stabilization of the previous stroke. Recurrence of stroke increases likelihood of disability-mortality associated with stroke. Systematic evaluation of stroke cases can help to reduce the risk of recurrence. Objective: In order to predict ischemic strokes which carry the risk of recurrence, our study aimed to compare data related to risk factors, stroke type, etiology and disability-mortality rates associated with stroke. Material and method: Our study including patients with recurrent ischemic stroke admitted to our hospital Neurology department between February 2010 and June 2011. Information about previous strokes and demographics were recorded. Risk factors were classified. Disability-mortality rates and secondary prevention treatment at recurrent stroke onset were evaluated. Results: 151 patients with recurrent ischemic stroke were included in our study. The mean age was 71.35 ± 12.06. The most frequent risk factors were hypertension, hyperlipidemia, coronary artery disease and atrial fibrillation. The most frequent recurrence etiology was cardiac embolic events. 53.2% of patients were receiving antiplatelet, 10.4% of patients were receiving anticoagulation therapy. 26.5% of patients died. The mean of modified Rankin score of patients was significantly higher at the recurrent ischemic stroke than the previous ischemic stroke. Conclusion: Knowing the etiological factor can help to predict recurrence of stroke and prevent death. Effective treatment of modifiable risk factors in recurrent stroke groups is very important in primary and secondary stroke prevention. Recurrent stroke prevention is very important in prognosis, disability and financial basis all around the world.
Journal of Stroke and Cerebrovascular Diseases, 2014
Background: Acetylsalicylic acid (ASA) and warfarin are used to prevent ischemic cerebrovascular ... more Background: Acetylsalicylic acid (ASA) and warfarin are used to prevent ischemic cerebrovascular events. They have serious complications including intracranial hemorrhages (ICHs). Warfarin-related intracerebral hemorrhage (ich) incidence is .2%-5% in population that accounts for 10%-12% of all ichs. In this article, we investigated the profile of ASA and warfarin-related spontaneous ICHs in comparison with ICHs without any drug use (WADU) with their clinical, radiological, and biochemical properties. Methods: In all, 486 patients aged 18-101 years with spontaneous ICHs were included. Patients constituted 4 separate groups: users of warfarin, ASA, ASA 1 warfarin, and WADU. Clinical, neurological, etiological, and radiological data of these patients were compared. Results: There were 32 patients in warfarin, 58 patients in ASA, and 7 in warfarin 1 ASA group. Most of the patients were in no drug group (389 patients). The most frequent type of hemorrhage was supratentorial intraparenchymal hemorrhage. The most common accompanying disease was hypertension. The number of female patients was statistically significant in the warfarin group. Glasgow Coma Scale (GCS), accompanying diseases, opening of the hematoma to the ventricle, localization of the hemorrhage, age of the patient, and activated partial thromboplastin time level are all related to the outcome of patients. Warfarin users had worst mortality rate. Conclusions: Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors. It is possible that patients with these unfavorable prognostic factors cannot survive.
Journal of Clinical Psychopharmacology, 2011
Critical Care Medicine, 2010
Brain death is the colloquial name for human death determined by tests showing irreversible cessa... more Brain death is the colloquial name for human death determined by tests showing irreversible cessation of the clinical functions of the brain. Spontaneous and reflex movements have been described in brain death. The aim of this report is to describe a brain-dead patient with unusual motor movements. The patient was followed and her motor movements were videotaped. We report the presence of extensive and long-lasting fasciculations in a patient who fulfilled the criteria for brain death. We describe and show on videotape a brain-dead patient with rare motor movements. We suggest that fasciculations outlined in this study has to be accepted as motor symptoms in brain death patients.
Clinical Neurology and Neurosurgery, 2013
To date, very few studies have paid attention to the joint sense (proprioception) of toes other t... more To date, very few studies have paid attention to the joint sense (proprioception) of toes other than the big toe. We evaluated the sensitivity of joint position sense at the joint of the great toe in comparison to other digits, and with that determined by the dual digit stimulation test, in a sample of healthy normal controls and patients with clinical diagnosis of the lemniscal system dysfunction. Seventy-two patients with lemniscal system dysfunction (55 clinically definitive multiple sclerosis, 17 vasculitis) and 110 healthy volunteers participated in the study. All subjects underwent the joint position sense test of all digits of upper and lower extremities. The position sense resulting from the combined operation of the joints of the second and the fourth digits (simultaneous two digits position sense) was also measured and subsequently compared with the results of the great toe position sense. Upper extremities: no difference was found in recognition of the position sense in the single digits of the upper extremities between patients and healthy volunteers. There was a significant difference in the dual joint position test of the right upper extremity between patients and the case group (p<0.05) but not in the left upper extremity. Lower extremities: there was no significant difference in proprioception of the great toe neither in the right and nor in the left side between patients and normal subjects. However, the joint position sense of other single digits was deteriorated in the patients, a difference that was significant compared to normal controls (p<0.05). Additionally, patients and normal controls displayed a difference in dual digit position sense of the right and left lower extremities (p<0.05). We show in this paper that the proprioception of simultaneous dual digits is diminished in patients when compared to a single digit position sense. Moreover, the great toe proprioception is less sensitive than other digits. Taken together, these observations lend evidence for a new clinical method which we named as dual joint position test. We suggest this novel method offers clinical utility to demonstrate lemniscal system dysfunction.
Acta Neurologica Belgica, 2014
Spontaneous and reflex movements have been described in brain death and these unusual movements m... more Spontaneous and reflex movements have been described in brain death and these unusual movements might cause uncertainties in diagnosis. In this study we evaluated the presence of spinal reflexes in patients who fulfilled the criteria for brain death. Thirty-two (22 %) of 144 patients presented unexpected motor movements spontaneously or during examinations. These patients exhibited the following signs: undulating toe, increased deep tendon reflexes, plantar responses, Lazarus sign, flexion-withdrawal reflex, facial myokymia, neck-arm flexion, finger jerks and fasciculations. In comparison, there were no significant differences in age, sex, etiology of brain death and hemodynamic laboratory findings in patients with and without reflex motor movement. Spinal reflexes should be well recognized by physicians and it should be born in mind that brain death can be determined in the presence of spinal reflexes.
Journal of the Neurological Sciences, 2013
Background: Recurrent stroke is defined as a new cerebrovascular event which occurs after the sta... more Background: Recurrent stroke is defined as a new cerebrovascular event which occurs after the stabilization of the previous stroke. Recurrence of stroke increases likelihood of disability-mortality associated with stroke. Systematic evaluation of stroke cases can help to reduce the risk of recurrence. Objective: In order to predict ischemic strokes which carry the risk of recurrence, our study aimed to compare data related to risk factors, stroke type, etiology and disability-mortality rates associated with stroke. Material and method: Our study including patients with recurrent ischemic stroke admitted to our hospital Neurology department between February 2010 and June 2011. Information about previous strokes and demographics were recorded. Risk factors were classified. Disability-mortality rates and secondary prevention treatment at recurrent stroke onset were evaluated. Results: 151 patients with recurrent ischemic stroke were included in our study. The mean age was 71.35 ± 12.06. The most frequent risk factors were hypertension, hyperlipidemia, coronary artery disease and atrial fibrillation. The most frequent recurrence etiology was cardiac embolic events. 53.2% of patients were receiving antiplatelet, 10.4% of patients were receiving anticoagulation therapy. 26.5% of patients died. The mean of modified Rankin score of patients was significantly higher at the recurrent ischemic stroke than the previous ischemic stroke. Conclusion: Knowing the etiological factor can help to predict recurrence of stroke and prevent death. Effective treatment of modifiable risk factors in recurrent stroke groups is very important in primary and secondary stroke prevention. Recurrent stroke prevention is very important in prognosis, disability and financial basis all around the world.
Journal of Stroke and Cerebrovascular Diseases, 2014
Background: Acetylsalicylic acid (ASA) and warfarin are used to prevent ischemic cerebrovascular ... more Background: Acetylsalicylic acid (ASA) and warfarin are used to prevent ischemic cerebrovascular events. They have serious complications including intracranial hemorrhages (ICHs). Warfarin-related intracerebral hemorrhage (ich) incidence is .2%-5% in population that accounts for 10%-12% of all ichs. In this article, we investigated the profile of ASA and warfarin-related spontaneous ICHs in comparison with ICHs without any drug use (WADU) with their clinical, radiological, and biochemical properties. Methods: In all, 486 patients aged 18-101 years with spontaneous ICHs were included. Patients constituted 4 separate groups: users of warfarin, ASA, ASA 1 warfarin, and WADU. Clinical, neurological, etiological, and radiological data of these patients were compared. Results: There were 32 patients in warfarin, 58 patients in ASA, and 7 in warfarin 1 ASA group. Most of the patients were in no drug group (389 patients). The most frequent type of hemorrhage was supratentorial intraparenchymal hemorrhage. The most common accompanying disease was hypertension. The number of female patients was statistically significant in the warfarin group. Glasgow Coma Scale (GCS), accompanying diseases, opening of the hematoma to the ventricle, localization of the hemorrhage, age of the patient, and activated partial thromboplastin time level are all related to the outcome of patients. Warfarin users had worst mortality rate. Conclusions: Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors. It is possible that patients with these unfavorable prognostic factors cannot survive.
Journal of Clinical Psychopharmacology, 2011
Critical Care Medicine, 2010
Brain death is the colloquial name for human death determined by tests showing irreversible cessa... more Brain death is the colloquial name for human death determined by tests showing irreversible cessation of the clinical functions of the brain. Spontaneous and reflex movements have been described in brain death. The aim of this report is to describe a brain-dead patient with unusual motor movements. The patient was followed and her motor movements were videotaped. We report the presence of extensive and long-lasting fasciculations in a patient who fulfilled the criteria for brain death. We describe and show on videotape a brain-dead patient with rare motor movements. We suggest that fasciculations outlined in this study has to be accepted as motor symptoms in brain death patients.
Clinical Neurology and Neurosurgery, 2013
To date, very few studies have paid attention to the joint sense (proprioception) of toes other t... more To date, very few studies have paid attention to the joint sense (proprioception) of toes other than the big toe. We evaluated the sensitivity of joint position sense at the joint of the great toe in comparison to other digits, and with that determined by the dual digit stimulation test, in a sample of healthy normal controls and patients with clinical diagnosis of the lemniscal system dysfunction. Seventy-two patients with lemniscal system dysfunction (55 clinically definitive multiple sclerosis, 17 vasculitis) and 110 healthy volunteers participated in the study. All subjects underwent the joint position sense test of all digits of upper and lower extremities. The position sense resulting from the combined operation of the joints of the second and the fourth digits (simultaneous two digits position sense) was also measured and subsequently compared with the results of the great toe position sense. Upper extremities: no difference was found in recognition of the position sense in the single digits of the upper extremities between patients and healthy volunteers. There was a significant difference in the dual joint position test of the right upper extremity between patients and the case group (p<0.05) but not in the left upper extremity. Lower extremities: there was no significant difference in proprioception of the great toe neither in the right and nor in the left side between patients and normal subjects. However, the joint position sense of other single digits was deteriorated in the patients, a difference that was significant compared to normal controls (p<0.05). Additionally, patients and normal controls displayed a difference in dual digit position sense of the right and left lower extremities (p<0.05). We show in this paper that the proprioception of simultaneous dual digits is diminished in patients when compared to a single digit position sense. Moreover, the great toe proprioception is less sensitive than other digits. Taken together, these observations lend evidence for a new clinical method which we named as dual joint position test. We suggest this novel method offers clinical utility to demonstrate lemniscal system dysfunction.
Acta Neurologica Belgica, 2014
Spontaneous and reflex movements have been described in brain death and these unusual movements m... more Spontaneous and reflex movements have been described in brain death and these unusual movements might cause uncertainties in diagnosis. In this study we evaluated the presence of spinal reflexes in patients who fulfilled the criteria for brain death. Thirty-two (22 %) of 144 patients presented unexpected motor movements spontaneously or during examinations. These patients exhibited the following signs: undulating toe, increased deep tendon reflexes, plantar responses, Lazarus sign, flexion-withdrawal reflex, facial myokymia, neck-arm flexion, finger jerks and fasciculations. In comparison, there were no significant differences in age, sex, etiology of brain death and hemodynamic laboratory findings in patients with and without reflex motor movement. Spinal reflexes should be well recognized by physicians and it should be born in mind that brain death can be determined in the presence of spinal reflexes.