Y. Le Gal - Academia.edu (original) (raw)
Papers by Y. Le Gal
Journal of Thermal Analysis and Calorimetry, 2009
Inorganic Chemistry, 2012
In the [Er(hfac) 3 (L)] 2 complex (1) (L = 4-tetrathiafulvalene-2,6pyridinecarboxylic acid dimeth... more In the [Er(hfac) 3 (L)] 2 complex (1) (L = 4-tetrathiafulvalene-2,6pyridinecarboxylic acid dimethyl ester), the Er(III) ion is bonded to the tridentate coordination site. Electrochemical and photophysical measurements in solution reveal that the tetrathiafulvalene moiety is a versatile antenna for erbium luminescence sensitization at 6540 cm −1 upon excitation in the low-energy charge transfer transition (donor to acceptor charge transfer) at 16600 cm −1 assigned via time-dependent density functional theory calculations.
Inorganic Chemistry, 2009
The reactions between the redox-active 4-(2-tetrathiafulvalenyl-ethenyl)pyridine ligand (TTF-CHdC... more The reactions between the redox-active 4-(2-tetrathiafulvalenyl-ethenyl)pyridine ligand (TTF-CHdCH-Py) and the tris(1,1,1,5,5,5-hexafluoroacetylacetonate)Ln(III) (Ln = La and Nd) lead to the formation of compounds with the formulas
![Research paper thumbnail of First Paramagnetic 4d Transition-Metal Complex with a Redox-Active Tetrathiafulvalene Derivative, [Ru(salen)(PPh 3 )(TTF-CHCH-Py)]BF 4 [salen 2− = N , N ′-Ethan-1,2-diylbis(salicylidenamine), PPh 3 = Triphenylphosphine, TTF-CHCH-Py = 4-(2-Tetrathiafulvalenylethenyl)pyridine]](https://attachments.academia-assets.com/51630828/thumbnails/1.jpg)
](Inorganic Chemistry, 2008
The first paramagnetic 4d transition-metal complex with a redoxactive tetrathiafulvalene ligand h... more The first paramagnetic 4d transition-metal complex with a redoxactive tetrathiafulvalene ligand has been synthesized. The preparation, X-ray structure, electrochemistry, and electron paramagnetic resonance measurements of [Ru(salen)(PPh 3 )(TTF-CHdCH-Py)](BF 4 ) [1(BF 4 )] are reported. The crystal structure reveals that the paramagnetic Ru III (s ) 1 / 2 ) center is in a tetragonally elongated octahedral geometry and the TTF-CHdCH-Py ligand is coordinated to the axial position of the Ru III ion through the nitrogen atom of the pyridine group. Thus, 1(BF 4 ) is an attractive precursor to study future π-4d interactions in dual-property conducting and magnetic materials.
European Journal of Organic Chemistry, 2006
One of the current objectives in the field of conducting materials derived from tetrathiafulvalen... more One of the current objectives in the field of conducting materials derived from tetrathiafulvalene (TTF) is to incorporate, within the same solid, two distinct physical properties such as magnetism and electronic conductivity while seeking to establish a magnetic coupling between the ...
naun.org
... Bui, Yann. Le Gal, Amani Mostafa and Guy Cathelineau B ... Nair, T. Furuike, H. Tamura, R. Ja... more ... Bui, Yann. Le Gal, Amani Mostafa and Guy Cathelineau B ... Nair, T. Furuike, H. Tamura, R. Jayakumar, Nanocomposite scallolds of bioactive glass ceramic nanoparticles disseminated chitosan matrix for tissue engineering applications, Carbohydrate Polymers 2009. ...
Chemical Communications, 2010
Synthesis, electrochemical, X-Ray structure, experimental and TD-DFT calculations of photophysica... more Synthesis, electrochemical, X-Ray structure, experimental and TD-DFT calculations of photophysical properties have been explored for the [Cu 2 (Cis-TTF-bis-CON-2-Py-N-oxide) 2 ] binuclear coordination complex involving Cis-tetrathiafulvalene-bis-amido-2pyridine-N-oxide as a bi-anionic ligand.
Applied Surface Science, 2008
Bioactive glasses in the system SiO2–CaO–Na2O–P2O5 were synthesized pure and doped with magnesium... more Bioactive glasses in the system SiO2–CaO–Na2O–P2O5 were synthesized pure and doped with magnesium or zinc by melt-derived method. The bioactivity was studied during in vitro assays: the ability of hydroxycarbonate apatite (HCA) layer to form on the glass surface was examined after contact with simulated body fluid (SBF). The X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) studies were performed before and after immersion in vitro assays. The SBF solutions were also analyzed using inductively coupled plasma-optical emission spectroscopy (ICP-OES).Introduction of magnesium and zinc as trace element induces several modifications on the observed phenomena at the glass surface and in SBF solution after immersion of the samples. The chemical durability of the glasses, the formation of the silica-rich layer and the crystallization of the HCA layer were affected, but not present the same modifications as the introduced doping element.
Applied Surface Science, 2011
Bioactivity and chemical reactivity of bioactive glass offer the ability to bond for soft and har... more Bioactivity and chemical reactivity of bioactive glass offer the ability to bond for soft and hard biological tissues. In this work, synthesis was carried out by using melting and rapid quenching. Strontium was introduced as trace element at different contents in the glass matrix, according to its concentration in the bone matrix. This chemical element presents a high interest in the bone metabolism activity. Investigations were conducted on the surface of biomaterials by using in vitro assay after immersion in SBF. Several physico-chemical methods such as SEM, FTIR, NMR, ICP-OES and MTT test were employed to highlight the effects of the Sr. The in vitro experiments showed that after soaking in SBF, the behaviour of pure glass is different compared to glass doped with Sr. NMR analyses showed in the 29Si MAS-NMR that glass matrix undergoes some changes after in vitro assays particularly the emergence of new components attributed to Q3(OH). The presence of Sr slowed down the bioactivity of glass after immersion in SBF. The non toxic character of compounds was confirmed. Introduction of Sr at 0.1wt % induce an enhancement of cells at about 14.3%.
The American surgeon, 1961
The Journal of thoracic and cardiovascular surgery, 1961
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris, Jan 22, 1956
Molecular marine biology and biotechnology, 1995
Two elastase isoforms were isolated from activated pancreatic extract of dogfish (Scyliorhinus ca... more Two elastase isoforms were isolated from activated pancreatic extract of dogfish (Scyliorhinus canicula). The purification procedures for both elastases included ammonium sulfate fractionation, ion exchange on DEAE cellulose and Mono-QHR column followed by gel filtration on PL-GFS (HPLC) column. The two isoenzymes, EI and EII, exhibit a high activity toward the specific elastase substrate succinyl-(ala)3-p-nitroanilide (SANA) with different kinetic parameters at 37 degrees C. However, the two different enzymes have similar properties on the basis of pH, temperature, and molecular weight study. The activity of both variants was completely inhibited by elastatinal, phenylmethyl sulfonyl fluoride, (PMSF), diisopropyl fluorophosphate, (iPr2-FP), but less by p-chloromercuribenzoic acid (PCMB) and soybean trypsin inhibitor. EI and EII have similar amino acid composition; their amino-terminal sequences have 85% homology with human and rat elastase 2.
Biomedicine / [publiée pour l'A.A.I.C.I.G.], Jan 28, 1975
Small amounts of whole blood from repeatedly bled donors increased the replacement rate of plasma... more Small amounts of whole blood from repeatedly bled donors increased the replacement rate of plasma protein in dogs, cats and rabbits subjected to hemorrhage. Results obtained within three hours were statistically significant. This strongly suggests that a chemical mediator, to hasten restoration of plasma protein levels, is released into the blood during hypoproteinemia.
Protoplasma, 1993
The amounts of nuclear DNA in ten species of seaweeds belonging to the Rhodophyceae, Phaeophyeeae... more The amounts of nuclear DNA in ten species of seaweeds belonging to the Rhodophyceae, Phaeophyeeae, and Chlorophyceae were determined by flow cytometric analysis of nuclei isolated from protoplasts. Genome size was determined from the fluorescence of the nuclei stained with ethidium bromide. The size of the nuclear genome ranged fi'om 0.13 pg per cell in the 1 C population of Ulva rigida to 3.40 pg per cell in the 2 C population of Sphacetaria sp. GC % analysis was based on staining with either Hoechst 33342 or mithramycin A, two fluorochromes specific for the bases A-T and G-C, respectiveIy. Two models were used for the estimation of the proportion of guanine plus cytosine in the nuclear genome. The first one was based on the linear relationships mithramycin A fluorescence/G-C content and ethidinm bromide fluorescence/total DNA content. The second model, based on the curvilinear relationships Hoechst 33342 fluorescence/A-T content and mithramycin A fluorescence/G-C content, resulted in comparatively more homogenous and consistent data and appears more accurate. Comparison with previous reports from other methods for the physical investigation of nuclear genomes shows that flow cytometry of nuclei isolated from protoplasts is an accurate, convenient and robust technique to assay for genome sizes and base pair composition in marine macroalgae, Abbreviations: A-T nucleic bases adenine and thymine; CRBC chicken red blood cell; FA LS forward-angle light scatter; G-C nucleic bases guanine and cytosine; SEIM sorbitoI enzymatic incubation medium; SWIM sea water incubation medium; Tm thermal denaturation temperature of DNA.
Annales d'anatomie pathologique
Bulletin de l'Association française pour l'étude du cancer, 1953
Neonatology, 1975
Cellulose acetate electrophoresis was applied to resolve, characterize and quantitate the five ma... more Cellulose acetate electrophoresis was applied to resolve, characterize and quantitate the five major plasma protein fractions of 7-day-old pigs. Purified Cohn fractions were added to the piglets plasma and the individual fractions characterized by similarities in mobilities. All mobilities were expressed relative to albumin. Relative percentages and concentrations of the electrophoretically separated plasma proteins were also calculated. The respective mean values for the plasma concentration of albumin, alpha-, beta, gamma-globulin and fibrinogen obtained from 45 piglets were 1.98, 0.93, 0.27, 0.60 and 1.49 g/100 ml, respectively.
Journal of Thermal Analysis and Calorimetry, 2009
Inorganic Chemistry, 2012
In the [Er(hfac) 3 (L)] 2 complex (1) (L = 4-tetrathiafulvalene-2,6pyridinecarboxylic acid dimeth... more In the [Er(hfac) 3 (L)] 2 complex (1) (L = 4-tetrathiafulvalene-2,6pyridinecarboxylic acid dimethyl ester), the Er(III) ion is bonded to the tridentate coordination site. Electrochemical and photophysical measurements in solution reveal that the tetrathiafulvalene moiety is a versatile antenna for erbium luminescence sensitization at 6540 cm −1 upon excitation in the low-energy charge transfer transition (donor to acceptor charge transfer) at 16600 cm −1 assigned via time-dependent density functional theory calculations.
Inorganic Chemistry, 2009
The reactions between the redox-active 4-(2-tetrathiafulvalenyl-ethenyl)pyridine ligand (TTF-CHdC... more The reactions between the redox-active 4-(2-tetrathiafulvalenyl-ethenyl)pyridine ligand (TTF-CHdCH-Py) and the tris(1,1,1,5,5,5-hexafluoroacetylacetonate)Ln(III) (Ln = La and Nd) lead to the formation of compounds with the formulas
Inorganic Chemistry, 2008
The first paramagnetic 4d transition-metal complex with a redoxactive tetrathiafulvalene ligand h... more The first paramagnetic 4d transition-metal complex with a redoxactive tetrathiafulvalene ligand has been synthesized. The preparation, X-ray structure, electrochemistry, and electron paramagnetic resonance measurements of [Ru(salen)(PPh 3 )(TTF-CHdCH-Py)](BF 4 ) [1(BF 4 )] are reported. The crystal structure reveals that the paramagnetic Ru III (s ) 1 / 2 ) center is in a tetragonally elongated octahedral geometry and the TTF-CHdCH-Py ligand is coordinated to the axial position of the Ru III ion through the nitrogen atom of the pyridine group. Thus, 1(BF 4 ) is an attractive precursor to study future π-4d interactions in dual-property conducting and magnetic materials.
European Journal of Organic Chemistry, 2006
One of the current objectives in the field of conducting materials derived from tetrathiafulvalen... more One of the current objectives in the field of conducting materials derived from tetrathiafulvalene (TTF) is to incorporate, within the same solid, two distinct physical properties such as magnetism and electronic conductivity while seeking to establish a magnetic coupling between the ...
naun.org
... Bui, Yann. Le Gal, Amani Mostafa and Guy Cathelineau B ... Nair, T. Furuike, H. Tamura, R. Ja... more ... Bui, Yann. Le Gal, Amani Mostafa and Guy Cathelineau B ... Nair, T. Furuike, H. Tamura, R. Jayakumar, Nanocomposite scallolds of bioactive glass ceramic nanoparticles disseminated chitosan matrix for tissue engineering applications, Carbohydrate Polymers 2009. ...
Chemical Communications, 2010
Synthesis, electrochemical, X-Ray structure, experimental and TD-DFT calculations of photophysica... more Synthesis, electrochemical, X-Ray structure, experimental and TD-DFT calculations of photophysical properties have been explored for the [Cu 2 (Cis-TTF-bis-CON-2-Py-N-oxide) 2 ] binuclear coordination complex involving Cis-tetrathiafulvalene-bis-amido-2pyridine-N-oxide as a bi-anionic ligand.
Applied Surface Science, 2008
Bioactive glasses in the system SiO2–CaO–Na2O–P2O5 were synthesized pure and doped with magnesium... more Bioactive glasses in the system SiO2–CaO–Na2O–P2O5 were synthesized pure and doped with magnesium or zinc by melt-derived method. The bioactivity was studied during in vitro assays: the ability of hydroxycarbonate apatite (HCA) layer to form on the glass surface was examined after contact with simulated body fluid (SBF). The X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) studies were performed before and after immersion in vitro assays. The SBF solutions were also analyzed using inductively coupled plasma-optical emission spectroscopy (ICP-OES).Introduction of magnesium and zinc as trace element induces several modifications on the observed phenomena at the glass surface and in SBF solution after immersion of the samples. The chemical durability of the glasses, the formation of the silica-rich layer and the crystallization of the HCA layer were affected, but not present the same modifications as the introduced doping element.
Applied Surface Science, 2011
Bioactivity and chemical reactivity of bioactive glass offer the ability to bond for soft and har... more Bioactivity and chemical reactivity of bioactive glass offer the ability to bond for soft and hard biological tissues. In this work, synthesis was carried out by using melting and rapid quenching. Strontium was introduced as trace element at different contents in the glass matrix, according to its concentration in the bone matrix. This chemical element presents a high interest in the bone metabolism activity. Investigations were conducted on the surface of biomaterials by using in vitro assay after immersion in SBF. Several physico-chemical methods such as SEM, FTIR, NMR, ICP-OES and MTT test were employed to highlight the effects of the Sr. The in vitro experiments showed that after soaking in SBF, the behaviour of pure glass is different compared to glass doped with Sr. NMR analyses showed in the 29Si MAS-NMR that glass matrix undergoes some changes after in vitro assays particularly the emergence of new components attributed to Q3(OH). The presence of Sr slowed down the bioactivity of glass after immersion in SBF. The non toxic character of compounds was confirmed. Introduction of Sr at 0.1wt % induce an enhancement of cells at about 14.3%.
The American surgeon, 1961
The Journal of thoracic and cardiovascular surgery, 1961
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris, Jan 22, 1956
Molecular marine biology and biotechnology, 1995
Two elastase isoforms were isolated from activated pancreatic extract of dogfish (Scyliorhinus ca... more Two elastase isoforms were isolated from activated pancreatic extract of dogfish (Scyliorhinus canicula). The purification procedures for both elastases included ammonium sulfate fractionation, ion exchange on DEAE cellulose and Mono-QHR column followed by gel filtration on PL-GFS (HPLC) column. The two isoenzymes, EI and EII, exhibit a high activity toward the specific elastase substrate succinyl-(ala)3-p-nitroanilide (SANA) with different kinetic parameters at 37 degrees C. However, the two different enzymes have similar properties on the basis of pH, temperature, and molecular weight study. The activity of both variants was completely inhibited by elastatinal, phenylmethyl sulfonyl fluoride, (PMSF), diisopropyl fluorophosphate, (iPr2-FP), but less by p-chloromercuribenzoic acid (PCMB) and soybean trypsin inhibitor. EI and EII have similar amino acid composition; their amino-terminal sequences have 85% homology with human and rat elastase 2.
Biomedicine / [publiée pour l'A.A.I.C.I.G.], Jan 28, 1975
Small amounts of whole blood from repeatedly bled donors increased the replacement rate of plasma... more Small amounts of whole blood from repeatedly bled donors increased the replacement rate of plasma protein in dogs, cats and rabbits subjected to hemorrhage. Results obtained within three hours were statistically significant. This strongly suggests that a chemical mediator, to hasten restoration of plasma protein levels, is released into the blood during hypoproteinemia.
Protoplasma, 1993
The amounts of nuclear DNA in ten species of seaweeds belonging to the Rhodophyceae, Phaeophyeeae... more The amounts of nuclear DNA in ten species of seaweeds belonging to the Rhodophyceae, Phaeophyeeae, and Chlorophyceae were determined by flow cytometric analysis of nuclei isolated from protoplasts. Genome size was determined from the fluorescence of the nuclei stained with ethidium bromide. The size of the nuclear genome ranged fi'om 0.13 pg per cell in the 1 C population of Ulva rigida to 3.40 pg per cell in the 2 C population of Sphacetaria sp. GC % analysis was based on staining with either Hoechst 33342 or mithramycin A, two fluorochromes specific for the bases A-T and G-C, respectiveIy. Two models were used for the estimation of the proportion of guanine plus cytosine in the nuclear genome. The first one was based on the linear relationships mithramycin A fluorescence/G-C content and ethidinm bromide fluorescence/total DNA content. The second model, based on the curvilinear relationships Hoechst 33342 fluorescence/A-T content and mithramycin A fluorescence/G-C content, resulted in comparatively more homogenous and consistent data and appears more accurate. Comparison with previous reports from other methods for the physical investigation of nuclear genomes shows that flow cytometry of nuclei isolated from protoplasts is an accurate, convenient and robust technique to assay for genome sizes and base pair composition in marine macroalgae, Abbreviations: A-T nucleic bases adenine and thymine; CRBC chicken red blood cell; FA LS forward-angle light scatter; G-C nucleic bases guanine and cytosine; SEIM sorbitoI enzymatic incubation medium; SWIM sea water incubation medium; Tm thermal denaturation temperature of DNA.
Annales d'anatomie pathologique
Bulletin de l'Association française pour l'étude du cancer, 1953
Neonatology, 1975
Cellulose acetate electrophoresis was applied to resolve, characterize and quantitate the five ma... more Cellulose acetate electrophoresis was applied to resolve, characterize and quantitate the five major plasma protein fractions of 7-day-old pigs. Purified Cohn fractions were added to the piglets plasma and the individual fractions characterized by similarities in mobilities. All mobilities were expressed relative to albumin. Relative percentages and concentrations of the electrophoretically separated plasma proteins were also calculated. The respective mean values for the plasma concentration of albumin, alpha-, beta, gamma-globulin and fibrinogen obtained from 45 piglets were 1.98, 0.93, 0.27, 0.60 and 1.49 g/100 ml, respectively.