Yan-Liang Yu - Academia.edu (original) (raw)

Papers by Yan-Liang Yu

Research paper thumbnail of Current Marital Status and Epigenetic Clocks Among Older Adults in the United States: Evidence From the Health and Retirement Study

Journal of Aging and Health

Objectives: This study examines how current marital status is associated with epigenetic aging. M... more Objectives: This study examines how current marital status is associated with epigenetic aging. Methods: Data from the 2016 Health and Retirement Study were used to examine marital status differences in the four epigenetic clocks, that is, GrimAge, DunedinPoAm, PhenoAge, and Zhang ( N = 3765). Weighted ordinary least square regression models were estimated separately for men and women. Results: Remarried, cohabiting, divorced/separated and widowed older adults showed greater epigenetic aging than the continuously married similarly among men and women. Distinct sex difference was observed among the never married. While never-married women exhibited greater epigenetic aging than their continuously married counterparts, older men in lifelong singlehood showed comparable epigenetic aging to their continuously married peers. Discussion: The findings speak to the importance of marital context for epigenetic aging in later life and the biological risk associated with lifelong singlehood fo...

Research paper thumbnail of Spousal synchrony in allostatic load among older couples in the Health and Retirement Study

Psychosomatic Medicine

Objectives Using national data from the Health and Retirement Study, this study examined interpar... more Objectives Using national data from the Health and Retirement Study, this study examined interpartner associations of allostatic load (AL) among 2,338 different-sex couples (N = 4,676 individuals) over a four-year period among older American couples from a dyadic approach. Methods AL was indexed by immune (c-reactive protein), metabolic (high-density lipoprotein cholesterol, total cholesterol and glycosylated hemoglobin), renal (cystatin C), cardiovascular (systolic and diastolic blood pressures, pulse rate) and anthropometric (waist and body mass index) parameters using the traditional count-based formulation. Actor-partner interdependence models were used to assess interpartner concordance in AL. Results Higher partners’ baseline AL was significantly associated with higher own AL both at baseline and four years later. Additionally, partners’ baseline AL was significantly associated with own AL four years later only in women but not men. Lastly, we did not observe any significant m...

Research paper thumbnail of Disparities by Race/Ethnicity and Immigration Status in Perceived Importance of and Access to Culturally Competent Health Care in the United States

Journal of Racial and Ethnic Health Disparities

Research paper thumbnail of Marital biography and chronic disease progression in mid- and late life

Research paper thumbnail of Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study

Psychology and Aging, 2020

This study examined whether the degree of novel information processing at work (NPW) attenuates c... more This study examined whether the degree of novel information processing at work (NPW) attenuates cognitive aging across 14 years for adults 50+ in the United States and how NPW links with job complexity. To answer these questions, we used data (N = 4,252) from the Health and Retirement Study. Detailed information on occupational characteristics from O*Net between 2000 and 2014 was used to assess NPW and matched with participants' occupational codes across time. Multilevel transition models were employed to estimate the relationship between NPW and cognitive functioning across time and to explore the moderating effect of cognitive level. Our results showed that exposure to more NPW across time attenuates cognitive decline as indicated by immediate word recall and serial 7s performance, while adjusting for baseline age, leisure, volunteering activities, cognition at previous wave, and other covariates. This buffering effect of NPW is reduced but sustained when controlling for change in job complexity, indicating that, as expected, NPW and job complexity are linked. We also found that particularly for workers with lower levels of cognitive performance, exposure to NPW across 14 years was linked with less decline in serial 7s performance (controlling for job complexity). This, however, was not the case for immediate word recall performance, which asks for further study. Overall, our findings suggest that mental stimulation through NPW is one mechanism (in the work context) that buffers cognitive decline. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Research paper thumbnail of Marital Quality and Salivary Telomere Length Among Older Men and Women in the United States

Journal of Aging and Health, 2020

Objective: The link between marital quality and cellular aging remains underexplored. This study ... more Objective: The link between marital quality and cellular aging remains underexplored. This study examined how both positive and negative marital quality were associated with salivary telomere length among partnered adults in the United States over the age of 50°years. Methods: Data were from the 2008 Health and Retirement Study ( N = 3203). Ordinary least squares regression was used to estimate the link between marital quality and telomere length. Results: While neither positive nor negative marital quality was significantly associated with telomere length among older women, positive and negative marital quality had an interacting effect on telomere length among men. Specifically, when negative marital quality was low, higher positive marital quality was associated with shorter telomere length, whereas when negative marital quality was high, higher positive marital quality was associated with longer telomere length. Discussion: The findings speak to the complex nature of intimate pa...

Research paper thumbnail of Spatiotemporal Patterns of Influenza-Associated Mortality in Japan , 1918-1920 : Implications for Flu Propagation

Research paper thumbnail of Comparing Multiple Statistical Software for Multiple-Indicator, Multiple-Cause Modeling: An Application of Gender Disparity in Adult Cognitive Functioning Using MIDUS II Dataset

Background: The Multiple-indicator, multiple-cause model (MIMIC) incorporates covariates of inter... more Background: The Multiple-indicator, multiple-cause model (MIMIC) incorporates covariates of interest in the factor analysis using structural equation modeling framework. The model provides rigorous results and becomes broadly available in multiple statistical software. The current study introduces the MIMIC model and how it can be implemented using statistical software SAS CALIS procedure, R lavaan package, and M plus version 8.0. Methods: In this paper, we first discussed the formulation of the MIMIC model with regard to model specification and identification. We then demonstrated the empirical application of the MIMIC model with the Midlife in the United States II (MIDUS II) Study (N=4,109) using SAS CALIS procedure, R lavaan package and M plus version 8.0 to examine gender disparities in cognitive functioning. The input, output, and diagram syntaxes of the three statistical software programs were also presented. Results In terms of data structure, all three statistical programs c...

Research paper thumbnail of How MDMA flows across the USA: evidence from price data

Global Crime, 2016

This study uses wholesale prices of MDMA for 59 cities in the USA published by the National Drug ... more This study uses wholesale prices of MDMA for 59 cities in the USA published by the National Drug Intelligence Center (NDIC) over the period of 2002–2011 to identify trafficking patterns of MDMA. Price differentials and correlations between pairs of cities are used to infer the presence of a link and the direction of flow of MDMA. The presence of inward and outward links is used to categorise each city as a ‘source’, ‘destination’, ‘transit’, or ‘weakly integrated’ city. The analysis identified low prices close to the Canadian and Mexican borders, in a number of cities such as Chicago, Miami, New York City, a trio of cities in the Carolinas, and along the West Coast. A number of these cities are linked to large numbers of other cities, indicating hub- or source-like status. The findings generate insights into the status of major US cities in the MDMA trafficking network.

Research paper thumbnail of Fertility Decline and the 1918 Influenza Pandemic in Taiwan

Biodemography and Social Biology, 2015

Research paper thumbnail of The 1918 influenza pandemic and subsequent birth deficit in Japan

Demographic Research, 2015

Research paper thumbnail of Interracial Marriage and Self-Reported Health of Whites and Blacks in the United States

Population Research and Policy Review

This study examines the self-reported health of 180,291 married non-Hispanic blacks and whites in... more This study examines the self-reported health of 180,291 married non-Hispanic blacks and whites in interracial versus endogamous marriages. Data are from the National Health Interview Survey pooled over the period 1997–2013. The results from ordinal logistic regressions show that non-Hispanic whites intermarried with non-Hispanic blacks, non-Hispanic whites intermarried with non-Hispanic other races, and non-Hispanic white women with Hispanic husbands report significantly poorer health than their endogamous counterparts. Furthermore, non-Hispanic whites with non-Hispanic black spouses also fare worse than their interracially married peers with Hispanic spouses. In contrast, the self-reported health of married non-Hispanic blacks shows no significant difference between the interracially and the endogamously married. Our findings highlight the theoretical significance of spousal characteristics and couple-level contexts in the household production of health.

Research paper thumbnail of Relationship quality and functional limitations among older adults with cardiovascular disease in the United States of America

Ageing and Society

Substantial research shows that cardiovascular disease is a major cause of disability in the Unit... more Substantial research shows that cardiovascular disease is a major cause of disability in the United States of America (USA) and worldwide. Despite the well-documented significance of intimate partnerships for cardiovascular health and disease management, how relationship quality contributes to the functional health of older adults diagnosed with cardiovascular disease is much less understood than mental health and mortality risk. Informed by the disablement process model and the lifecourse perspective, this study examines the association between relationship quality and functional limitations among partnered older adults aged 50 years and older diagnosed with cardiovascular disease in the USA. Data are from the Health and Retirement Study, 2006–2012 (N = 1,355). Multi-level linear regression analyses show that baseline negative relationship quality is significantly associated with increased functional limitations over the two- and four-year follow-ups. Additionally, the link between...

Research paper thumbnail of Marital biography and health in middle and late life

Couple relationships in the middle and later years: Their nature, complexity, and role in health and illness.

Research paper thumbnail of Life Course Pathways to Racial Disparities in Cognitive Impairment among Older Americans

Journal of health and social behavior, Jan 31, 2016

Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we... more Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we take advantage of the Health and Retirement Study (1998-2010) to assess how this racial divide in cognitive impairment is associated with the racial stratification of life course exposures and resources over a 12-year period among 8,946 non-Hispanic whites and blacks ages 65 and older in 1998. We find that blacks suffer from a higher risk of moderate/severe cognitive impairment at baseline and during the follow-up. Blacks are also more likely to report childhood adversity and to have grown up in the segregated South, and these early-life adversities put blacks at a significantly higher risk of cognitive impairment. Adulthood socioeconomic status is strongly associated with the risk of cognitive impairment, net of childhood conditions. However, racial disparities in cognitive impairment, though substantially reduced, are not eliminated when controlling for these life course factors.

Research paper thumbnail of Life Course Pathways to Racial Disparities in Cognitive Impairment among Older Americans

Journal of health and social behavior, Jan 31, 2016

Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we... more Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we take advantage of the Health and Retirement Study (1998-2010) to assess how this racial divide in cognitive impairment is associated with the racial stratification of life course exposures and resources over a 12-year period among 8,946 non-Hispanic whites and blacks ages 65 and older in 1998. We find that blacks suffer from a higher risk of moderate/severe cognitive impairment at baseline and during the follow-up. Blacks are also more likely to report childhood adversity and to have grown up in the segregated South, and these early-life adversities put blacks at a significantly higher risk of cognitive impairment. Adulthood socioeconomic status is strongly associated with the risk of cognitive impairment, net of childhood conditions. However, racial disparities in cognitive impairment, though substantially reduced, are not eliminated when controlling for these life course factors.

Research paper thumbnail of Current Marital Status and Epigenetic Clocks Among Older Adults in the United States: Evidence From the Health and Retirement Study

Journal of Aging and Health

Objectives: This study examines how current marital status is associated with epigenetic aging. M... more Objectives: This study examines how current marital status is associated with epigenetic aging. Methods: Data from the 2016 Health and Retirement Study were used to examine marital status differences in the four epigenetic clocks, that is, GrimAge, DunedinPoAm, PhenoAge, and Zhang ( N = 3765). Weighted ordinary least square regression models were estimated separately for men and women. Results: Remarried, cohabiting, divorced/separated and widowed older adults showed greater epigenetic aging than the continuously married similarly among men and women. Distinct sex difference was observed among the never married. While never-married women exhibited greater epigenetic aging than their continuously married counterparts, older men in lifelong singlehood showed comparable epigenetic aging to their continuously married peers. Discussion: The findings speak to the importance of marital context for epigenetic aging in later life and the biological risk associated with lifelong singlehood fo...

Research paper thumbnail of Spousal synchrony in allostatic load among older couples in the Health and Retirement Study

Psychosomatic Medicine

Objectives Using national data from the Health and Retirement Study, this study examined interpar... more Objectives Using national data from the Health and Retirement Study, this study examined interpartner associations of allostatic load (AL) among 2,338 different-sex couples (N = 4,676 individuals) over a four-year period among older American couples from a dyadic approach. Methods AL was indexed by immune (c-reactive protein), metabolic (high-density lipoprotein cholesterol, total cholesterol and glycosylated hemoglobin), renal (cystatin C), cardiovascular (systolic and diastolic blood pressures, pulse rate) and anthropometric (waist and body mass index) parameters using the traditional count-based formulation. Actor-partner interdependence models were used to assess interpartner concordance in AL. Results Higher partners’ baseline AL was significantly associated with higher own AL both at baseline and four years later. Additionally, partners’ baseline AL was significantly associated with own AL four years later only in women but not men. Lastly, we did not observe any significant m...

Research paper thumbnail of Disparities by Race/Ethnicity and Immigration Status in Perceived Importance of and Access to Culturally Competent Health Care in the United States

Journal of Racial and Ethnic Health Disparities

Research paper thumbnail of Marital biography and chronic disease progression in mid- and late life

Research paper thumbnail of Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study

Psychology and Aging, 2020

This study examined whether the degree of novel information processing at work (NPW) attenuates c... more This study examined whether the degree of novel information processing at work (NPW) attenuates cognitive aging across 14 years for adults 50+ in the United States and how NPW links with job complexity. To answer these questions, we used data (N = 4,252) from the Health and Retirement Study. Detailed information on occupational characteristics from O*Net between 2000 and 2014 was used to assess NPW and matched with participants' occupational codes across time. Multilevel transition models were employed to estimate the relationship between NPW and cognitive functioning across time and to explore the moderating effect of cognitive level. Our results showed that exposure to more NPW across time attenuates cognitive decline as indicated by immediate word recall and serial 7s performance, while adjusting for baseline age, leisure, volunteering activities, cognition at previous wave, and other covariates. This buffering effect of NPW is reduced but sustained when controlling for change in job complexity, indicating that, as expected, NPW and job complexity are linked. We also found that particularly for workers with lower levels of cognitive performance, exposure to NPW across 14 years was linked with less decline in serial 7s performance (controlling for job complexity). This, however, was not the case for immediate word recall performance, which asks for further study. Overall, our findings suggest that mental stimulation through NPW is one mechanism (in the work context) that buffers cognitive decline. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Research paper thumbnail of Marital Quality and Salivary Telomere Length Among Older Men and Women in the United States

Journal of Aging and Health, 2020

Objective: The link between marital quality and cellular aging remains underexplored. This study ... more Objective: The link between marital quality and cellular aging remains underexplored. This study examined how both positive and negative marital quality were associated with salivary telomere length among partnered adults in the United States over the age of 50°years. Methods: Data were from the 2008 Health and Retirement Study ( N = 3203). Ordinary least squares regression was used to estimate the link between marital quality and telomere length. Results: While neither positive nor negative marital quality was significantly associated with telomere length among older women, positive and negative marital quality had an interacting effect on telomere length among men. Specifically, when negative marital quality was low, higher positive marital quality was associated with shorter telomere length, whereas when negative marital quality was high, higher positive marital quality was associated with longer telomere length. Discussion: The findings speak to the complex nature of intimate pa...

Research paper thumbnail of Spatiotemporal Patterns of Influenza-Associated Mortality in Japan , 1918-1920 : Implications for Flu Propagation

Research paper thumbnail of Comparing Multiple Statistical Software for Multiple-Indicator, Multiple-Cause Modeling: An Application of Gender Disparity in Adult Cognitive Functioning Using MIDUS II Dataset

Background: The Multiple-indicator, multiple-cause model (MIMIC) incorporates covariates of inter... more Background: The Multiple-indicator, multiple-cause model (MIMIC) incorporates covariates of interest in the factor analysis using structural equation modeling framework. The model provides rigorous results and becomes broadly available in multiple statistical software. The current study introduces the MIMIC model and how it can be implemented using statistical software SAS CALIS procedure, R lavaan package, and M plus version 8.0. Methods: In this paper, we first discussed the formulation of the MIMIC model with regard to model specification and identification. We then demonstrated the empirical application of the MIMIC model with the Midlife in the United States II (MIDUS II) Study (N=4,109) using SAS CALIS procedure, R lavaan package and M plus version 8.0 to examine gender disparities in cognitive functioning. The input, output, and diagram syntaxes of the three statistical software programs were also presented. Results In terms of data structure, all three statistical programs c...

Research paper thumbnail of How MDMA flows across the USA: evidence from price data

Global Crime, 2016

This study uses wholesale prices of MDMA for 59 cities in the USA published by the National Drug ... more This study uses wholesale prices of MDMA for 59 cities in the USA published by the National Drug Intelligence Center (NDIC) over the period of 2002–2011 to identify trafficking patterns of MDMA. Price differentials and correlations between pairs of cities are used to infer the presence of a link and the direction of flow of MDMA. The presence of inward and outward links is used to categorise each city as a ‘source’, ‘destination’, ‘transit’, or ‘weakly integrated’ city. The analysis identified low prices close to the Canadian and Mexican borders, in a number of cities such as Chicago, Miami, New York City, a trio of cities in the Carolinas, and along the West Coast. A number of these cities are linked to large numbers of other cities, indicating hub- or source-like status. The findings generate insights into the status of major US cities in the MDMA trafficking network.

Research paper thumbnail of Fertility Decline and the 1918 Influenza Pandemic in Taiwan

Biodemography and Social Biology, 2015

Research paper thumbnail of The 1918 influenza pandemic and subsequent birth deficit in Japan

Demographic Research, 2015

Research paper thumbnail of Interracial Marriage and Self-Reported Health of Whites and Blacks in the United States

Population Research and Policy Review

This study examines the self-reported health of 180,291 married non-Hispanic blacks and whites in... more This study examines the self-reported health of 180,291 married non-Hispanic blacks and whites in interracial versus endogamous marriages. Data are from the National Health Interview Survey pooled over the period 1997–2013. The results from ordinal logistic regressions show that non-Hispanic whites intermarried with non-Hispanic blacks, non-Hispanic whites intermarried with non-Hispanic other races, and non-Hispanic white women with Hispanic husbands report significantly poorer health than their endogamous counterparts. Furthermore, non-Hispanic whites with non-Hispanic black spouses also fare worse than their interracially married peers with Hispanic spouses. In contrast, the self-reported health of married non-Hispanic blacks shows no significant difference between the interracially and the endogamously married. Our findings highlight the theoretical significance of spousal characteristics and couple-level contexts in the household production of health.

Research paper thumbnail of Relationship quality and functional limitations among older adults with cardiovascular disease in the United States of America

Ageing and Society

Substantial research shows that cardiovascular disease is a major cause of disability in the Unit... more Substantial research shows that cardiovascular disease is a major cause of disability in the United States of America (USA) and worldwide. Despite the well-documented significance of intimate partnerships for cardiovascular health and disease management, how relationship quality contributes to the functional health of older adults diagnosed with cardiovascular disease is much less understood than mental health and mortality risk. Informed by the disablement process model and the lifecourse perspective, this study examines the association between relationship quality and functional limitations among partnered older adults aged 50 years and older diagnosed with cardiovascular disease in the USA. Data are from the Health and Retirement Study, 2006–2012 (N = 1,355). Multi-level linear regression analyses show that baseline negative relationship quality is significantly associated with increased functional limitations over the two- and four-year follow-ups. Additionally, the link between...

Research paper thumbnail of Marital biography and health in middle and late life

Couple relationships in the middle and later years: Their nature, complexity, and role in health and illness.

Research paper thumbnail of Life Course Pathways to Racial Disparities in Cognitive Impairment among Older Americans

Journal of health and social behavior, Jan 31, 2016

Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we... more Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we take advantage of the Health and Retirement Study (1998-2010) to assess how this racial divide in cognitive impairment is associated with the racial stratification of life course exposures and resources over a 12-year period among 8,946 non-Hispanic whites and blacks ages 65 and older in 1998. We find that blacks suffer from a higher risk of moderate/severe cognitive impairment at baseline and during the follow-up. Blacks are also more likely to report childhood adversity and to have grown up in the segregated South, and these early-life adversities put blacks at a significantly higher risk of cognitive impairment. Adulthood socioeconomic status is strongly associated with the risk of cognitive impairment, net of childhood conditions. However, racial disparities in cognitive impairment, though substantially reduced, are not eliminated when controlling for these life course factors.

Research paper thumbnail of Life Course Pathways to Racial Disparities in Cognitive Impairment among Older Americans

Journal of health and social behavior, Jan 31, 2016

Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we... more Blacks are especially hard hit by cognitive impairment at older ages compared to whites. Here, we take advantage of the Health and Retirement Study (1998-2010) to assess how this racial divide in cognitive impairment is associated with the racial stratification of life course exposures and resources over a 12-year period among 8,946 non-Hispanic whites and blacks ages 65 and older in 1998. We find that blacks suffer from a higher risk of moderate/severe cognitive impairment at baseline and during the follow-up. Blacks are also more likely to report childhood adversity and to have grown up in the segregated South, and these early-life adversities put blacks at a significantly higher risk of cognitive impairment. Adulthood socioeconomic status is strongly associated with the risk of cognitive impairment, net of childhood conditions. However, racial disparities in cognitive impairment, though substantially reduced, are not eliminated when controlling for these life course factors.