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Papers by Yasemin Gültekin

Research paper thumbnail of Role of Tactile Noise in the Control of Digit Normal Force

Frontiers in Psychology, 2021

Whenever we grasp and lift an object, our tactile system provides important information on the co... more Whenever we grasp and lift an object, our tactile system provides important information on the contact location and the force exerted on our skin. The human brain integrates signals from multiple sites for a coherent representation of object shape, inertia, weight, and other material properties. It is still an open question whether the control of grasp force occurs at the level of individual fingers or whether it is also influenced by the control and the signals from the other fingers of the same hand. In this work, we approached this question by asking participants to lift, transport, and replace a sensorized object, using three- and four-digit grasp. Tactile input was altered by covering participant's fingertips with a rubber thimble, which reduced the reliability of the tactile sensory input. In different experimental conditions, we covered between one and three fingers opposing the thumb. Normal forces at each finger and the thumb were recorded while grasping and holding the...

Research paper thumbnail of Toxicity level of the tulathromycin on BHK cell culture and the effect on infective titers of foot and mouth disease viruses

Medycyna Weterynaryjna, 2020

The aim of the study was to evaluate the cytotoxicity of tulathromycin (macrolide antibiotic) on ... more The aim of the study was to evaluate the cytotoxicity of tulathromycin (macrolide antibiotic) on BHK-21 An30 cells and to determine the effect on FMD (Serotypes; A/TUR/11, O/TUR/07, Asia-1/TUR/15) virus propagation in vitro. In the result of MTT tests and cell culture studies, the non-toxic upper concentration of the tulathromycin limit for BHK-21 An30 cell culture was determined as 30 µg/ml in terms of cell morphologies and numbers. The mean FMD 146S virus particle values produced in BHK-21 An30 cell cultures containing 30 µg/ml of tulathromycin were found to be 0.47, 0.57 and 0.25 µg/ml; the mean infective titer determined as 107.03, 106.23 and 107.40 pfu/ml for A/TUR/11, O/TUR/07 and Asia-1/TUR/15, respectively. In the FMD virus cultures produced with medium containing penicillin-streptomycin, the mean values of 146S virus particles were determined to be A/TUR/11, O/TUR/07 and the Asia-1/TUR/15 serotypes were 0.50, 0.55, and 0.32 µg/ml, respectively, while the mean infective tite...

Research paper thumbnail of Determination of the effects of Enrofloxacin, Linco-Spectin and Florphenicol antibiotics on BHK-21 cell culture and FMD 146S Virus particles-infective titers

Etlik Veteriner Mikrobiyoloji Dergisi, 2020

Enrofloxacin, linko-spectin and florfenicol antibiotics were intended to be used in the BHK-21 An... more Enrofloxacin, linko-spectin and florfenicol antibiotics were intended to be used in the BHK-21 An30 cells and the foot and mouth disease virus (FMDV) culture during the vaccine production process. Methylthiazolyldiphenyltetrazolium bromide (MTT) and cell cultures assays were performed in the BHK-21 An30 cells treated with the antibiotics that took place in this study to determine the concentration that inhibits cell proliferation and adverse effects on cell morphology. Virus cultures were performed by inoculating of FMDV serotypes (A/TUR/11, O/TUR/07, Asia-1/TUR/15) to the treated cell cultures with the antibiotics. 146S and infective titres of the obtained virus suspensions were determined. The non-toxic upper limit was determined to be 15 μg /ml for enrofloxacin and 300 μg/ ml for linco-spectin in terms of cell morphology and cell numbers versus positive control (gentamycin, penicillinstreptomycin) and negative control (antibiotic-free medium) as a result of MTT and cell culture tests on BHK cells. It was observed that florfenicol also inhibited cell proliferation and induced cell degeneration, even at a concentration of 5 μg/ml. The mean 146S values of FMD virus cultures containing enrofloxacin and linco-spectin were determined to be 0.49, 0.46, 0.53, 0.47 and 0.30, 0.28 µg/ml for serotype A/TUR/11, O/TUR/07 and Asia-1/TUR/15 respectively. The mean values of the infective titres were 10 7,

Research paper thumbnail of Role of Tactile Noise in the Control of Digit Normal Force

Frontiers in Psychology, 2021

Whenever we grasp and lift an object, our tactile system provides important information on the co... more Whenever we grasp and lift an object, our tactile system provides important information on the contact location and the force exerted on our skin. The human brain integrates signals from multiple sites for a coherent representation of object shape, inertia, weight, and other material properties. It is still an open question whether the control of grasp force occurs at the level of individual fingers or whether it is also influenced by the control and the signals from the other fingers of the same hand. In this work, we approached this question by asking participants to lift, transport, and replace a sensorized object, using three- and four-digit grasp. Tactile input was altered by covering participant's fingertips with a rubber thimble, which reduced the reliability of the tactile sensory input. In different experimental conditions, we covered between one and three fingers opposing the thumb. Normal forces at each finger and the thumb were recorded while grasping and holding the...

Research paper thumbnail of Toxicity level of the tulathromycin on BHK cell culture and the effect on infective titers of foot and mouth disease viruses

Medycyna Weterynaryjna, 2020

The aim of the study was to evaluate the cytotoxicity of tulathromycin (macrolide antibiotic) on ... more The aim of the study was to evaluate the cytotoxicity of tulathromycin (macrolide antibiotic) on BHK-21 An30 cells and to determine the effect on FMD (Serotypes; A/TUR/11, O/TUR/07, Asia-1/TUR/15) virus propagation in vitro. In the result of MTT tests and cell culture studies, the non-toxic upper concentration of the tulathromycin limit for BHK-21 An30 cell culture was determined as 30 µg/ml in terms of cell morphologies and numbers. The mean FMD 146S virus particle values produced in BHK-21 An30 cell cultures containing 30 µg/ml of tulathromycin were found to be 0.47, 0.57 and 0.25 µg/ml; the mean infective titer determined as 107.03, 106.23 and 107.40 pfu/ml for A/TUR/11, O/TUR/07 and Asia-1/TUR/15, respectively. In the FMD virus cultures produced with medium containing penicillin-streptomycin, the mean values of 146S virus particles were determined to be A/TUR/11, O/TUR/07 and the Asia-1/TUR/15 serotypes were 0.50, 0.55, and 0.32 µg/ml, respectively, while the mean infective tite...

Research paper thumbnail of Determination of the effects of Enrofloxacin, Linco-Spectin and Florphenicol antibiotics on BHK-21 cell culture and FMD 146S Virus particles-infective titers

Etlik Veteriner Mikrobiyoloji Dergisi, 2020

Enrofloxacin, linko-spectin and florfenicol antibiotics were intended to be used in the BHK-21 An... more Enrofloxacin, linko-spectin and florfenicol antibiotics were intended to be used in the BHK-21 An30 cells and the foot and mouth disease virus (FMDV) culture during the vaccine production process. Methylthiazolyldiphenyltetrazolium bromide (MTT) and cell cultures assays were performed in the BHK-21 An30 cells treated with the antibiotics that took place in this study to determine the concentration that inhibits cell proliferation and adverse effects on cell morphology. Virus cultures were performed by inoculating of FMDV serotypes (A/TUR/11, O/TUR/07, Asia-1/TUR/15) to the treated cell cultures with the antibiotics. 146S and infective titres of the obtained virus suspensions were determined. The non-toxic upper limit was determined to be 15 μg /ml for enrofloxacin and 300 μg/ ml for linco-spectin in terms of cell morphology and cell numbers versus positive control (gentamycin, penicillinstreptomycin) and negative control (antibiotic-free medium) as a result of MTT and cell culture tests on BHK cells. It was observed that florfenicol also inhibited cell proliferation and induced cell degeneration, even at a concentration of 5 μg/ml. The mean 146S values of FMD virus cultures containing enrofloxacin and linco-spectin were determined to be 0.49, 0.46, 0.53, 0.47 and 0.30, 0.28 µg/ml for serotype A/TUR/11, O/TUR/07 and Asia-1/TUR/15 respectively. The mean values of the infective titres were 10 7,