Yoav Pikkel - Academia.edu (original) (raw)
Papers by Yoav Pikkel
BMJ case reports, 2014
We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open f... more We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open fractures of the right tibia and fibula with extensive bone and soft tissue loss as well as an open fracture of the left calcaneus as the result of a high-energy blast injury. She was successfully treated with repeated debridement procedures, external fixation with acute temporary shortening and angulation of the right leg and skin grafting to both lower limbs.
BMJ case reports, 2014
A 54-year-old male patient presented to our clinic with acute angle-closure glaucoma and panuveit... more A 54-year-old male patient presented to our clinic with acute angle-closure glaucoma and panuveitis in both eyes after being treated with topiramate for binge eating and obesity. This case report emphasises the hazardous side effects of treatment with topiramate with unusual indication and the precaution a caretaker must take when treating a patient.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Jan 20, 2016
The objective of this study is to assess the effects of changes in barometric pressure and outdoo... more The objective of this study is to assess the effects of changes in barometric pressure and outdoor temperature on the incidence of different subtypes of intracerebral hemorrhage (ICH). Consecutive patients with primary supratentorial ICH were included. All patients resided in the same geographic area. We compared patients with subcortical ICH to those with cortical ICH. Meteorological data were continuously accrued. High-risk ICH days were defined as those on which 1 or more patients with ICH were admitted and compared to non-high-risk days. We analyzed the relationship between spontaneous ICH location and averaged daily atmospheric pressures and temperatures. We included 206 patients (147 with deep ICH and 59 with lobar ICH). Patients with deep ICH were younger (P < .001), more often had histories of diabetes, smoking and previous lacunar strokes, and were more often male (P < .01 for all). Drops in mean air pressure 2 days prior to the ictus were associated with deep but not...
Case reports in ophthalmology, 2014
Acute retinal necrosis (ARN) is a viral syndrome consisting of uveitis/vitritis, occlusive vascul... more Acute retinal necrosis (ARN) is a viral syndrome consisting of uveitis/vitritis, occlusive vasculitis and peripheral necrosis. Few incidents are reported in children. The etiology is reactivated herpes simplex virus (HSV) or varicella-zoster virus (VZV). Treatment with acyclovir is often used. The administration of oral glucocorticosteroids is of unproven benefit. Prognosis is variable but poor. Three weeks after contracting mild chickenpox, a healthy 4-year-old girl developed blurred vision in her right eye. Severely reduced visual acuity was noted, together with anterior uveitis, 'mutton-fat' precipitates and vitral flare. Retinal vasculitis with necrosis was present. Serology for toxoplasma, cytomegalovirus and HIV was negative, while HSV and VZV IgG antibodies were positive. She was treated with 30 mg/kg of intravenous methylprednisolone (3 days), 30 mg of oral prednisone (3 days), and tapering for 8 weeks. Intravenous acyclovir was given for 10 days, followed by oral ac...
Public Health, 2015
Glaucoma is the second leading cause of blindness and a leading cause for irreversible visual los... more Glaucoma is the second leading cause of blindness and a leading cause for irreversible visual loss. 1 The type of disease in the elderly population is mainly primary open-angle glaucoma (POAG); primary closed-angle glaucoma (PCAG) is more associated with genetic factors. Recognized risk factors for POAG include: ocular hypertension (OHT), 2 increasing age 3 ; myopia, 4 certain ethnicities, 5 family history of glaucoma, 6 diabetes, 7 and arterial hypertension. 8 Due to the progressive natural course of glaucoma, early detection, appropriate medical or surgical treatment, and monitoring are particularly important, to decrease the risk of vision loss and blindness and the associated social burden, and to increase quality of life. 9 However, a population-based cohort study of individuals aged 55 years and above demonstrated that most of those with incident POAG were unaware of having this condition. 3 Due to the importance of early detection of glaucoma, the Ophthalmology Department of Ziv Medical Center launched an annual one-day screening program. They assessed cup-to-disk ratio and ocular tension, which are the main factors that are examined in glaucoma screening. The authors also checked for known co-morbidities and family history of glaucoma.
BMJ case reports, 2014
We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open f... more We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open fractures of the right tibia and fibula with extensive bone and soft tissue loss as well as an open fracture of the left calcaneus as the result of a high-energy blast injury. She was successfully treated with repeated debridement procedures, external fixation with acute temporary shortening and angulation of the right leg and skin grafting to both lower limbs.
The Israel Medical Association journal : IMAJ, 2015
Meningitis and meningoencephalitis pose major risks of morbidity and mortality. To describe 20 ye... more Meningitis and meningoencephalitis pose major risks of morbidity and mortality. To describe 20 years of experience treating infections of the central nervous system in Israel Defense Force (IDF) soldiers, including the common presentations, pathogens and sequelae, and to identify risk groups among soldiers. All soldiers who were admitted to the Hadassah University Medical Center (both campuses: Ein Kerem and Mt. Scopus) due to meningitis and meningoencephalitis from January 1993 to January 2014 were included in this retrospective study. Clinical, laboratory and radiologic data were reviewed from their hospital and army medical corps files. Attention was given to patients' military job description, i.e., combat vs. non-combat soldier, soldiers in training, and medical personnel. We identified 97 cases of suspected meningitis or meningoencephalitis. Six were mistakenly filed and these patients were found to have other disorders. Four soldiers were diagnosed with epidural abscess a...
BMJ case reports, 2014
We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open f... more We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open fractures of the right tibia and fibula with extensive bone and soft tissue loss as well as an open fracture of the left calcaneus as the result of a high-energy blast injury. She was successfully treated with repeated debridement procedures, external fixation with acute temporary shortening and angulation of the right leg and skin grafting to both lower limbs.
BMJ case reports, 2014
A 54-year-old male patient presented to our clinic with acute angle-closure glaucoma and panuveit... more A 54-year-old male patient presented to our clinic with acute angle-closure glaucoma and panuveitis in both eyes after being treated with topiramate for binge eating and obesity. This case report emphasises the hazardous side effects of treatment with topiramate with unusual indication and the precaution a caretaker must take when treating a patient.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Jan 20, 2016
The objective of this study is to assess the effects of changes in barometric pressure and outdoo... more The objective of this study is to assess the effects of changes in barometric pressure and outdoor temperature on the incidence of different subtypes of intracerebral hemorrhage (ICH). Consecutive patients with primary supratentorial ICH were included. All patients resided in the same geographic area. We compared patients with subcortical ICH to those with cortical ICH. Meteorological data were continuously accrued. High-risk ICH days were defined as those on which 1 or more patients with ICH were admitted and compared to non-high-risk days. We analyzed the relationship between spontaneous ICH location and averaged daily atmospheric pressures and temperatures. We included 206 patients (147 with deep ICH and 59 with lobar ICH). Patients with deep ICH were younger (P < .001), more often had histories of diabetes, smoking and previous lacunar strokes, and were more often male (P < .01 for all). Drops in mean air pressure 2 days prior to the ictus were associated with deep but not...
Case reports in ophthalmology, 2014
Acute retinal necrosis (ARN) is a viral syndrome consisting of uveitis/vitritis, occlusive vascul... more Acute retinal necrosis (ARN) is a viral syndrome consisting of uveitis/vitritis, occlusive vasculitis and peripheral necrosis. Few incidents are reported in children. The etiology is reactivated herpes simplex virus (HSV) or varicella-zoster virus (VZV). Treatment with acyclovir is often used. The administration of oral glucocorticosteroids is of unproven benefit. Prognosis is variable but poor. Three weeks after contracting mild chickenpox, a healthy 4-year-old girl developed blurred vision in her right eye. Severely reduced visual acuity was noted, together with anterior uveitis, 'mutton-fat' precipitates and vitral flare. Retinal vasculitis with necrosis was present. Serology for toxoplasma, cytomegalovirus and HIV was negative, while HSV and VZV IgG antibodies were positive. She was treated with 30 mg/kg of intravenous methylprednisolone (3 days), 30 mg of oral prednisone (3 days), and tapering for 8 weeks. Intravenous acyclovir was given for 10 days, followed by oral ac...
Public Health, 2015
Glaucoma is the second leading cause of blindness and a leading cause for irreversible visual los... more Glaucoma is the second leading cause of blindness and a leading cause for irreversible visual loss. 1 The type of disease in the elderly population is mainly primary open-angle glaucoma (POAG); primary closed-angle glaucoma (PCAG) is more associated with genetic factors. Recognized risk factors for POAG include: ocular hypertension (OHT), 2 increasing age 3 ; myopia, 4 certain ethnicities, 5 family history of glaucoma, 6 diabetes, 7 and arterial hypertension. 8 Due to the progressive natural course of glaucoma, early detection, appropriate medical or surgical treatment, and monitoring are particularly important, to decrease the risk of vision loss and blindness and the associated social burden, and to increase quality of life. 9 However, a population-based cohort study of individuals aged 55 years and above demonstrated that most of those with incident POAG were unaware of having this condition. 3 Due to the importance of early detection of glaucoma, the Ophthalmology Department of Ziv Medical Center launched an annual one-day screening program. They assessed cup-to-disk ratio and ocular tension, which are the main factors that are examined in glaucoma screening. The authors also checked for known co-morbidities and family history of glaucoma.
BMJ case reports, 2014
We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open f... more We present the case of an 8-year-old girl casualty of the Syrian conflict who arrived with open fractures of the right tibia and fibula with extensive bone and soft tissue loss as well as an open fracture of the left calcaneus as the result of a high-energy blast injury. She was successfully treated with repeated debridement procedures, external fixation with acute temporary shortening and angulation of the right leg and skin grafting to both lower limbs.
The Israel Medical Association journal : IMAJ, 2015
Meningitis and meningoencephalitis pose major risks of morbidity and mortality. To describe 20 ye... more Meningitis and meningoencephalitis pose major risks of morbidity and mortality. To describe 20 years of experience treating infections of the central nervous system in Israel Defense Force (IDF) soldiers, including the common presentations, pathogens and sequelae, and to identify risk groups among soldiers. All soldiers who were admitted to the Hadassah University Medical Center (both campuses: Ein Kerem and Mt. Scopus) due to meningitis and meningoencephalitis from January 1993 to January 2014 were included in this retrospective study. Clinical, laboratory and radiologic data were reviewed from their hospital and army medical corps files. Attention was given to patients' military job description, i.e., combat vs. non-combat soldier, soldiers in training, and medical personnel. We identified 97 cases of suspected meningitis or meningoencephalitis. Six were mistakenly filed and these patients were found to have other disorders. Four soldiers were diagnosed with epidural abscess a...