Youssef Yasin - Academia.edu (original) (raw)

Papers by Youssef Yasin

Research paper thumbnail of Antibacterial Activity of Ethanolic Extract of Cinnamon Bark and Honey and Their Combination Effects Against Acne Causing Bacteria

Propionibacterium acnes and Staphylococcus epidermidis are the major skin bacteria that cause the... more Propionibacterium acnes and Staphylococcus epidermidis are the major skin bacteria that cause the formation of acne. The present study was conducted to investigate antibacterial activity of ethanolic extract of cinnamon bark, honey and their combination against acne bacteria. The antibacterial activity of extract of cinnamon bark and honey were investigated against P. acnes and S. epidermidis using disc diffusion method. Minimum Inhibitory Concentration (MIC) and minimal bactericidal concentration (MBC) were performed using Clinical and Laboratory Standard Institute (CLSI) methods. The interaction combination between extract of cinnamon bark and honey was determined by using a checkerboards method. The results showed that he MIC of extract of cinnamon bark and honey against P. acne were 256 µg/mL and 50% v/v, respectively, while against S. epidermidis were 1024 µg/mL and 50% v/v, respectively. The MBC of extract of cinnamon against P. acnes and S. epidermidis were more t...

Research paper thumbnail of Antibacterial activity of zinc oxide nanoparticle suspensions on food-borne pathogens

International Journal of Dairy Technology, 2012

ABSTRACT Nanoparticles (NPs) are increasingly recognised for their utility in biological applicat... more ABSTRACT Nanoparticles (NPs) are increasingly recognised for their utility in biological applications including nanomedicine and food safety. The present study investigated the antibacterial activity of zinc oxide (ZnO) when tested against the Gram‐negative bacteria Escherichia coli as well as the Gram‐positive bacterium Staphylococcus aureus, and the effect was more pronounced with the Gram‐positive than with the Gram‐negative bacteria. ZnO NPs also exhibited a preferential ability to suppress growth of E. coli and S. aureus in milk. This study suggested that the application of ZnO NPs as antibacterial agents in food systems and medicine may be effective at inhibiting certain pathogens.

Research paper thumbnail of Effect of Ganoderma Fungi and Spirulina Alga in The Liver Tissue of Diabetic Mice Developed with Aloxane and Lead-Induced Anemia

Tikrit Journal for Agricultural Sciences

The study was conducted on male mice (Albino mice), which ranged in age from (2-3) months and wei... more The study was conducted on male mice (Albino mice), which ranged in age from (2-3) months and weights (25 - 30) g. The experiment was conducted in the General Company for the manufacture of medicines and medical supplies - Samarra. And for the period from the beginning of October 2017 to the end of March 2018, Used 42 animals were distributed in seven groups, each containing 6 animals, to determine the effects of both gannoderma and spirulina in laboratory mice induced by diabetes mellitus with a Aloxan at 150 mg / kg Bw. In laboratory mice with anemia with lead acetate of 50 mg / Kg body weight for 30 days (except control group) At the end of the 30-day feeding period. control group on the regular diet. control group infected diabetes and drugs on the regular diet. The group of diabetic animals treated with ganoderma fungi powder (47 mg / kg body weight). The group of diabetic animals and the treatment of spirulina algae powder (33 mg / kg body weight). group of animals infected wi...

Research paper thumbnail of Evaluation of metformin performance on alloxan-induced diabetic rabbits

Journal of Medicine and Life

This study aimed to evaluate metformin as a widely used oral hypoglycemic agent and identify the ... more This study aimed to evaluate metformin as a widely used oral hypoglycemic agent and identify the effects on biochemical and antioxidant body systems of rabbits. Four groups of rabbits were randomly allocated as the control, the alloxan-induced diabetic, metformin-treated, and alloxan treated with metformin. The results revealed that alloxan leads to significant elevation in glucose (Glc) levels, malondialdehyde (MDA), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), triglycerides (TGs), and total cholesterol (TCH), and a significant decline in high-density lipoprotein (HDL) and glutathione (GSH) as compared with the control group. Metformin alone caused a significant decline in Glc and HDL with significant elevation in LDL and MDA without significant changes in TCH, TGs, VLDL, and GSH. When metformin was offered as a treatment for alloxan-induced diabetic animals, it caused a significant decline in Glc, TCH, TGs, LDL, and VLDL levels with significant elevation in ...

Research paper thumbnail of Experimental study for the effect of methyl rednisolone on the sexual hormones levels

Proceedings of the 4th International Scientific Conference of Cihan University-Erbil on Biological Sciences, 2017

Methylprednisolone is one of the steroid drugs (Glucocorticoid) , which is used in many medical c... more Methylprednisolone is one of the steroid drugs (Glucocorticoid) , which is used in many medical conditions including allergy , ulcerative Colitis , Lupus , psoriasis , respiratory disorders and immune inhibitory. Fifty sex adult male rats weighing (225-250) gm where used, and randomly divided into four equal groups, which treated with daily by three different concentration from Methylprednisolone drug : (10,30,40) mg/kg/day. The blood samples is taken in the first and second week of dosage from all groups. The results of this study showed that the drug has obvious effect on the sexual hormones (Testosterone hormone , LH hormone, FSH hormone and Prolactin hormone) in sera of rats under investigation , In which the maximum change in the levels of hormones were showed in sera of groups with high dosage from drug (40 mg/kg) and the minimum change at the low dosage (20 mg/kg). The results are indicated there is significant decrease in testosterone levels, LH and FSH the decrease is continued until the second week. As for the Prolactin hormone , the results indicated there is a significant increased and increase is continued until the second week .

Research paper thumbnail of Antibacterial Activity of Ethanolic Extract of Cinnamon Bark and Honey and Their Combination Effects Against Acne Causing Bacteria

Propionibacterium acnes and Staphylococcus epidermidis are the major skin bacteria that cause the... more Propionibacterium acnes and Staphylococcus epidermidis are the major skin bacteria that cause the formation of acne. The present study was conducted to investigate antibacterial activity of ethanolic extract of cinnamon bark, honey and their combination against acne bacteria. The antibacterial activity of extract of cinnamon bark and honey were investigated against P. acnes and S. epidermidis using disc diffusion method. Minimum Inhibitory Concentration (MIC) and minimal bactericidal concentration (MBC) were performed using Clinical and Laboratory Standard Institute (CLSI) methods. The interaction combination between extract of cinnamon bark and honey was determined by using a checkerboards method. The results showed that he MIC of extract of cinnamon bark and honey against P. acne were 256 µg/mL and 50% v/v, respectively, while against S. epidermidis were 1024 µg/mL and 50% v/v, respectively. The MBC of extract of cinnamon against P. acnes and S. epidermidis were more t...

Research paper thumbnail of Antibacterial activity of zinc oxide nanoparticle suspensions on food-borne pathogens

International Journal of Dairy Technology, 2012

ABSTRACT Nanoparticles (NPs) are increasingly recognised for their utility in biological applicat... more ABSTRACT Nanoparticles (NPs) are increasingly recognised for their utility in biological applications including nanomedicine and food safety. The present study investigated the antibacterial activity of zinc oxide (ZnO) when tested against the Gram‐negative bacteria Escherichia coli as well as the Gram‐positive bacterium Staphylococcus aureus, and the effect was more pronounced with the Gram‐positive than with the Gram‐negative bacteria. ZnO NPs also exhibited a preferential ability to suppress growth of E. coli and S. aureus in milk. This study suggested that the application of ZnO NPs as antibacterial agents in food systems and medicine may be effective at inhibiting certain pathogens.

Research paper thumbnail of Effect of Ganoderma Fungi and Spirulina Alga in The Liver Tissue of Diabetic Mice Developed with Aloxane and Lead-Induced Anemia

Tikrit Journal for Agricultural Sciences

The study was conducted on male mice (Albino mice), which ranged in age from (2-3) months and wei... more The study was conducted on male mice (Albino mice), which ranged in age from (2-3) months and weights (25 - 30) g. The experiment was conducted in the General Company for the manufacture of medicines and medical supplies - Samarra. And for the period from the beginning of October 2017 to the end of March 2018, Used 42 animals were distributed in seven groups, each containing 6 animals, to determine the effects of both gannoderma and spirulina in laboratory mice induced by diabetes mellitus with a Aloxan at 150 mg / kg Bw. In laboratory mice with anemia with lead acetate of 50 mg / Kg body weight for 30 days (except control group) At the end of the 30-day feeding period. control group on the regular diet. control group infected diabetes and drugs on the regular diet. The group of diabetic animals treated with ganoderma fungi powder (47 mg / kg body weight). The group of diabetic animals and the treatment of spirulina algae powder (33 mg / kg body weight). group of animals infected wi...

Research paper thumbnail of Evaluation of metformin performance on alloxan-induced diabetic rabbits

Journal of Medicine and Life

This study aimed to evaluate metformin as a widely used oral hypoglycemic agent and identify the ... more This study aimed to evaluate metformin as a widely used oral hypoglycemic agent and identify the effects on biochemical and antioxidant body systems of rabbits. Four groups of rabbits were randomly allocated as the control, the alloxan-induced diabetic, metformin-treated, and alloxan treated with metformin. The results revealed that alloxan leads to significant elevation in glucose (Glc) levels, malondialdehyde (MDA), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), triglycerides (TGs), and total cholesterol (TCH), and a significant decline in high-density lipoprotein (HDL) and glutathione (GSH) as compared with the control group. Metformin alone caused a significant decline in Glc and HDL with significant elevation in LDL and MDA without significant changes in TCH, TGs, VLDL, and GSH. When metformin was offered as a treatment for alloxan-induced diabetic animals, it caused a significant decline in Glc, TCH, TGs, LDL, and VLDL levels with significant elevation in ...

Research paper thumbnail of Experimental study for the effect of methyl rednisolone on the sexual hormones levels

Proceedings of the 4th International Scientific Conference of Cihan University-Erbil on Biological Sciences, 2017

Methylprednisolone is one of the steroid drugs (Glucocorticoid) , which is used in many medical c... more Methylprednisolone is one of the steroid drugs (Glucocorticoid) , which is used in many medical conditions including allergy , ulcerative Colitis , Lupus , psoriasis , respiratory disorders and immune inhibitory. Fifty sex adult male rats weighing (225-250) gm where used, and randomly divided into four equal groups, which treated with daily by three different concentration from Methylprednisolone drug : (10,30,40) mg/kg/day. The blood samples is taken in the first and second week of dosage from all groups. The results of this study showed that the drug has obvious effect on the sexual hormones (Testosterone hormone , LH hormone, FSH hormone and Prolactin hormone) in sera of rats under investigation , In which the maximum change in the levels of hormones were showed in sera of groups with high dosage from drug (40 mg/kg) and the minimum change at the low dosage (20 mg/kg). The results are indicated there is significant decrease in testosterone levels, LH and FSH the decrease is continued until the second week. As for the Prolactin hormone , the results indicated there is a significant increased and increase is continued until the second week .