Yunus Emiroglu - Academia.edu (original) (raw)

Papers by Yunus Emiroglu

Research paper thumbnail of Sağ pulmoner artere embolize olan atriyal septal oklüder cihazının perkütan başarılı çıkarılması

Türk kardiyoloji derneği arşivi, Jul 1, 2014

Research paper thumbnail of Association of Indicators of Dehydration and Haemoconcentration with the Coronary Slow Flow Phenomenon

Objectives: The coronary slow flow phenomenon (CSFP), characterized by decreased distal progressi... more Objectives: The coronary slow flow phenomenon (CSFP), characterized by decreased distal progression of dye to coronary arteries, is a distinct angiographic phenomenon and little is known about its pathophysiology. Although several hypotheses have been suggested, the underlying mechanism of CSFP has not been well established yet. The aim of this study was to determine the roles of indicators of dehydration and haemoconcentration in CSFP which have blood flow abnormality effects. Methods: The study consisted of 33 patients with CSFP (group 1), and 31 normal subjects as control group (group 2) detected by coronary angiography. CSFP was diagnosed by the TIMI frame count method. Serum electrolytes, osmolarity and haematological parameters were measured. Results: Compared with control subjects, patient with CSFP had increased levels of calculated osmolarity, tonicity, sodium, glucose and blood urea nitrogen (BUN). Significant differences were also observed in the haematocrit, haemoglobin concentration, and calculated osmolarity but not in total cholesterol and albumin. Conclusions: The results of the present study indicate that the markers of haemoconcentration and dehydration are significantly associated with CSFP. The markers may be important in the coronary blood flow anomaly.

Research paper thumbnail of Chronic Total Occlusion of the Left Main Coronary Artery with Preserved Left Ventricular Function: Case Report

Türkiye klinikleri cardiovascular sciences, 2012

Research paper thumbnail of Long-Term Exposure to Biomass Fuel and Its Relation to Systolic and Diastolic Biventricular Performance in Addition to Obstructive and Restrictive Lung Diseases

Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, Aug 24, 2010

Background: Previous studies have demonstrated an increased risk for cardiovascular events and pu... more Background: Previous studies have demonstrated an increased risk for cardiovascular events and pulmonary disease in patients with biomass fuel exposure (BFE). However, biventricular heart function has yet to be investigated in these patients. Left ventricular (LV) myocardial performance index (LVMPI), which is an index of global ventricular function, incorporates ejection, isovolumic relaxation, and contraction times. In this study, pulmonary function and biventricular heart function were investigated in nonsmoking female patients with BFE. Methods: Our study population consisted of 46 female patients with BFE (group 1) and 31 control subjects (group 2). Pulmonary function tests and transthoracic echocardiographic examination were performed. Right ventricular myocardial performance index (RVMPI) and LVMPI were obtained by tissue Doppler imaging echocardiography (TDI). Results: BFE caused obstructive and restrictive spirometric impairments. RVMPI was higher in group 1 (0.55 ± 0.07) than group 2 (0.46 ± 0.06) (P = 0.042) and LVMPI was higher in group 1 (0.54 ± 0.08) than group 2 (0.47 ± 0.05) (P = 0.032). Also, pulmonary artery systolic pressure was higher in group 1 than group 2 (P = 0.02). Conclusions: BFE causes both obstructive and/or restrictive lung disease and systolic and diastolic biventricular dysfunction. Nonetheless, long-term studies are needed to understand on BFErelated ventricular dysfunctions and to document subsequent cardiovascular events.

Research paper thumbnail of Dilatation of the Ascending Aorta Is Associated with Low Serum Prolidase Activity

Tohoku Journal of Experimental Medicine, 2010

Research paper thumbnail of Heterosis and Combining Ability in a Diallel Cross of Turnip Rape Genotypes

Turkish Journal of Field Crops, Feb 1, 2014

This study was undertaken to estimate the combining ability in turnip rape through diallel analys... more This study was undertaken to estimate the combining ability in turnip rape through diallel analysis involving five diverse genotypes. A 5 x 5 full diallel crosses study, including the reciprocals, with turnip rape (Brassica rapa L.) was performed to determine both the magnitude of gene action and heterotic performance of the crosses for seed yield and important yield components. Field experiments were conducted at Uludag University, Bursa, Turkey, during the 2008-2009 and 2009-2010 growing seasons. All 20 F 1 hybrids and their parents were sown in a randomized complete block design with 3 replicates. During both years, the mean squares of the general combining ability (GCA), specific combining ability (SCA) and reciprocal combining ability (RCA) were statistically significant for all traits evaluated. The parent Malvira was a good general combiner because this parent had the highest significant positive GCA effects for all the characteristics evaluated. In addition, Lenox proved to be a good general combiner for plant height. The significant positive mid-parent and high-parent heterosis values were obtained with several crosses in important yield components. In conclusion, the parents used in this study exhibited positive GCA effects for seed yield. Therefore they could be considered as promising parents in the production of F 1 hybrids and in further breeding studies.

Research paper thumbnail of The Effect of Cilostazol on Right Heart Function and Pulmonary Pressure

Cardiovascular Therapeutics, Nov 27, 2013

Introduction: Cilostazol is a pde3 inhibitor and used to treat peripheral arterial disease. There... more Introduction: Cilostazol is a pde3 inhibitor and used to treat peripheral arterial disease. There are few reports on the influence of cilostazol on heart. Aims: The aim of this study was to assess this effect on right ventricular function and pulmonary artery pressure Methods: Forty patients with normal left and right ventricular ejection fraction and mild or moderate pulmonary artery hypertension were enrolled in the study. Right ventricular function was assessed by tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), tissue Doppler imaging (TDI) and two-dimensional speckle-tracking echocardiography (2D-STE) before and after oral administration of cilostazol. Also pulmonary artery pressure assessed before and after administration of cilostazol. Results: After cilostazol administration, there were significant increases in the TAPSE (1.9±0.3cm vs. 2.2±0.3cm, p<0.001). Peak longitudinal strain (-18.7±4.5% vs.-21.3 ±3.7 %, p=0.001), isovolumetric acceleration (IVA) (176.6±62.7 cm/sec 2 vs.200.6±61.9cm/sec 2 , p=0.025), right ventricular FAC increased significantly (37.6 ± 8.0% vs 41.5±8.9%, p<0.001). Pulmonary artery pressure decreased significantly (39.9±7.9 vs. 36.6±5.5mmHg, p=0.001) after cilostazol administration. Conclusion: Our study demonstrated that cilostazol improved right ventricular systolic function and reduced pulmonary artery pressure.

Research paper thumbnail of Left ventricular noncompaction in a patient with multiminicore disease

Journal of Cardiovascular Medicine, Oct 1, 2012

Although cardiac impairment secondary to respiratory involvement is not uncommonly observed in th... more Although cardiac impairment secondary to respiratory involvement is not uncommonly observed in the classic phenotype of multiminicore disease (MmD), primary cardiomyopathies have not been reported in the case of MmD. Left ventricular noncompaction is a cardiomyopathy ...

Research paper thumbnail of BNP levels in patients with long-term exposure to biomass fuel and its relation to right ventricular function

Pulmonary Pharmacology & Therapeutics, Oct 1, 2010

Previous studies have demonstrated a consistent increased risk for cardiovascular events and pulm... more Previous studies have demonstrated a consistent increased risk for cardiovascular events and pulmonary disease in patients with biomass fuel exposure (BFE). However right ventricular (RV) function have not been investigated yet in these patients. In this study, pulmonary function, right ventricular function and their relations with Brain Natriuretic Peptide (BNP) were investigated in non-smoking female patients with BFE. Methods: Our study population consisted of 39 female patients with BFE (group 1) and, 31 control subjects (group 2). Pulmonary function tests and transthoracic echocardiographic examination were performed. Right ventricular volumes, diameters and tissue velocities were obtained by tissue Doppler echocardiography. BNP levels were measured and correlated to right ventricular measurements and pulmonary artery pressure. Results: In BFE group, obstructive and restrictive spirometric findings were found. RV diameters, volumes and pulmonary artery pressure were higher in group 1 than group 2. BNP levels were well correlated with right ventricular end diastolic diameter and pulmonary artery pressure. A suspicion is also arised that toxic chemicals in biomass fuel may play a role in RV dysfunction. Conclusion: Biomass fuel exposure not only cause obstructive and/or restrictive lung disease but also leads to systolic and diastolic right ventricular dysfunction. BNP levels may be used to monitor pulmonary artery pressure and right ventricular enlargement in these patients.

Research paper thumbnail of The Effect Of Uncomplicated Percutaneus Coronary Intervention On Brachial Artery Flow Mediated Dilatation in Patients With Stable Angina Pectoris

İzmir tepecik eğitim hastanesi dergisi, 2008

Research paper thumbnail of Evaluation of Left Ventricular Function by Conventional Echocardiography and Tissue Doppler Imaging in Patients with Acute and Chronic Mitral Regurgitation

Journal of Medical Ultrasound, Dec 1, 2011

Open access under CC BY-NC-ND license. functions by TDI were also relatively preserved in patient... more Open access under CC BY-NC-ND license. functions by TDI were also relatively preserved in patients with acute MR when compared with those with chronic MR.

Research paper thumbnail of The Prognostic Value of Combined Fractional Flow Reserve and TIMI Frame Count Measurements in Patients with Stable Angina Pectoris and Acute Coronary Syndrome

Journal of Interventional Cardiology, Jul 8, 2010

Background: The aim of this study was to evaluate the prognostic value of different fractional fl... more Background: The aim of this study was to evaluate the prognostic value of different fractional flow reserve (FFR) cutoff values and corrected thrombolysis in myocardial infarction frame (TIMI) count (CTFC) measurements in a series of consecutive patients with moderate coronary lesions, including patients with unstable angina, myocardial infarction, and/or positive noninvasive functional test findings. Methods: We included 162 consecutive coronary patients in whom revascularization of a moderate coronary lesion was deferred based on a FFR value ≥0.75. Patients were divided according to the results of the intracoronary pressure and flow measurements into four groups: group A: 0.75

Research paper thumbnail of Uric Acid as a Marker of Oxidative Stress in Dilatation of the Ascending Aorta

American Journal of Hypertension, Feb 1, 2011

background Increased serum uric acid (Ua) has been shown to directly promote oxidative stress. Re... more background Increased serum uric acid (Ua) has been shown to directly promote oxidative stress. Recent studies point toward a role for oxidative stress in the pathogenesis of ascending aortic aneurysms (ascaas). This study was designed to examine the relationship between serum Ua concentrations, total antioxidant reductive capacity, and ascaas. Methods The serum Ua concentrations, total antioxidant reductive capacity were compared in 60 patients with ascending aortic dilatation (ectasia group (3.8-4.3 cm), 34 patients; aneurysmal group (≥4.4 cm), 26 patients) vs. 30 control subjects. The patients were evaluated by a complete transthoracic echocardiographic examination including measurement of the aortic dimensions. results The serum Ua concentration and total antioxidant reductive capacity were significantly higher in patients with ascaas. In multiple linear regression analysis, hypertension and serum Ua concentration were significantly associated with aortic dilatation (β = 0.3, P = 0.03; β = 0.15, P < 0.001, respectively). conclusions In conclusion, we found that serum Ua concentration and total antioxidant capacity (TaC) were significantly associated with aortic dilatation. The higher serum Ua concentration may be responsible for the elevated serum antioxidant capacity that was observed among individuals with ascaa. Large-scale epidemiological studies conducted over several years are required to correlate the crosssectional findings from this study with clinical outcome.

Research paper thumbnail of OP-014 the Effect of Cilostazol on Right Heart Function and Pulmonary Pressure

International Journal of Cardiology, Mar 1, 2013

Research paper thumbnail of Association Between Apolipoprotein-B100 and Apolipoprotein-A1 in Patients with Coronary Slow Flow

DergiPark (Istanbul University), Feb 1, 2009

Objective: Although several hypotheses have been suggested, the underlying mechanism of coronary ... more Objective: Although several hypotheses have been suggested, the underlying mechanism of coronary slow flow phenomenon (CSFP) has not been well established yet. The aim of this study was to determine the roles of plasma apolipoprotein-B100 (Apo-B) and apolipoprotein-A1 (Apo-A1) in CSFP which have an atherogenic effect and anti-atherogenic effects respectively. Methods: The study consisted of 31 patients with CSFP (group 1), 28 normal subjects as control group (group 2) and 30 patients with coronary artery disease (CAD) (group 3) detected by coronary angiography. CSFP was diagnosed by the TIMI frame count method. Blood Apo-B, Apo-A1, Apo-B/Apo-A1 ratio, and demographic parameters were compared between the groups. Results: The Apo-B values were 93±25 mg/dL, 90±26 mg/dL, and 106±27 mg/dL in groups 1, 2 and 3, respectively (p=0.048 between group 1 and 3, p=0.041 between group 2 and 3, p= NS between group 1 and 2). The Apo-A1values were 127±14 mg/dL, 125±21 mg/dL and 106±27 mg/dL in groups 1, 2 and 3 respectively (p=0.028 between group 1 and 3, p=0.021 between group 2 and 3, p= NS between group 1 and 2). The apo-B/apo-A1 ratio were 0.73±0.18, 0.69±0.23 and 0.98±0.20 in groups 1, 2 and 3 respectively (p=0.017 between group 1 and 3, p=0.010 between group 2 and 3, p= NS between group 1 and 2). Conclusion: Although lower levels of plasma Apo-A1 and higher levels of Apo-B and the ratio of Apo-B to Apo-A1 are related with CAD, there is no relationship between these apolipoproteins and CSFP.

Research paper thumbnail of Angiographic demonstration of percutaneous retrieval of an interatrial septal occluder device embolized into the right pulmonary artery

Türk kardiyoloji derneği arşivi, 2014

Research paper thumbnail of Aritmojenik Sa¤ Ventrikül Displazisi ile Birlikte Olan Biküspit Aort Kapak

Koşuyolu Heart Journal, 2010

Research paper thumbnail of Myocardial bridging as a cause of acute myocardial infarction: a case report-2

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002PMCID:PMC128836.Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Research paper thumbnail of Systolic compression at the mid-portion of LAD at the LAO view

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128836/Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Research paper thumbnail of ECG shows acute anteroseptal wall myocardial infarction

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128836/Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Research paper thumbnail of Sağ pulmoner artere embolize olan atriyal septal oklüder cihazının perkütan başarılı çıkarılması

Türk kardiyoloji derneği arşivi, Jul 1, 2014

Research paper thumbnail of Association of Indicators of Dehydration and Haemoconcentration with the Coronary Slow Flow Phenomenon

Objectives: The coronary slow flow phenomenon (CSFP), characterized by decreased distal progressi... more Objectives: The coronary slow flow phenomenon (CSFP), characterized by decreased distal progression of dye to coronary arteries, is a distinct angiographic phenomenon and little is known about its pathophysiology. Although several hypotheses have been suggested, the underlying mechanism of CSFP has not been well established yet. The aim of this study was to determine the roles of indicators of dehydration and haemoconcentration in CSFP which have blood flow abnormality effects. Methods: The study consisted of 33 patients with CSFP (group 1), and 31 normal subjects as control group (group 2) detected by coronary angiography. CSFP was diagnosed by the TIMI frame count method. Serum electrolytes, osmolarity and haematological parameters were measured. Results: Compared with control subjects, patient with CSFP had increased levels of calculated osmolarity, tonicity, sodium, glucose and blood urea nitrogen (BUN). Significant differences were also observed in the haematocrit, haemoglobin concentration, and calculated osmolarity but not in total cholesterol and albumin. Conclusions: The results of the present study indicate that the markers of haemoconcentration and dehydration are significantly associated with CSFP. The markers may be important in the coronary blood flow anomaly.

Research paper thumbnail of Chronic Total Occlusion of the Left Main Coronary Artery with Preserved Left Ventricular Function: Case Report

Türkiye klinikleri cardiovascular sciences, 2012

Research paper thumbnail of Long-Term Exposure to Biomass Fuel and Its Relation to Systolic and Diastolic Biventricular Performance in Addition to Obstructive and Restrictive Lung Diseases

Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, Aug 24, 2010

Background: Previous studies have demonstrated an increased risk for cardiovascular events and pu... more Background: Previous studies have demonstrated an increased risk for cardiovascular events and pulmonary disease in patients with biomass fuel exposure (BFE). However, biventricular heart function has yet to be investigated in these patients. Left ventricular (LV) myocardial performance index (LVMPI), which is an index of global ventricular function, incorporates ejection, isovolumic relaxation, and contraction times. In this study, pulmonary function and biventricular heart function were investigated in nonsmoking female patients with BFE. Methods: Our study population consisted of 46 female patients with BFE (group 1) and 31 control subjects (group 2). Pulmonary function tests and transthoracic echocardiographic examination were performed. Right ventricular myocardial performance index (RVMPI) and LVMPI were obtained by tissue Doppler imaging echocardiography (TDI). Results: BFE caused obstructive and restrictive spirometric impairments. RVMPI was higher in group 1 (0.55 ± 0.07) than group 2 (0.46 ± 0.06) (P = 0.042) and LVMPI was higher in group 1 (0.54 ± 0.08) than group 2 (0.47 ± 0.05) (P = 0.032). Also, pulmonary artery systolic pressure was higher in group 1 than group 2 (P = 0.02). Conclusions: BFE causes both obstructive and/or restrictive lung disease and systolic and diastolic biventricular dysfunction. Nonetheless, long-term studies are needed to understand on BFErelated ventricular dysfunctions and to document subsequent cardiovascular events.

Research paper thumbnail of Dilatation of the Ascending Aorta Is Associated with Low Serum Prolidase Activity

Tohoku Journal of Experimental Medicine, 2010

Research paper thumbnail of Heterosis and Combining Ability in a Diallel Cross of Turnip Rape Genotypes

Turkish Journal of Field Crops, Feb 1, 2014

This study was undertaken to estimate the combining ability in turnip rape through diallel analys... more This study was undertaken to estimate the combining ability in turnip rape through diallel analysis involving five diverse genotypes. A 5 x 5 full diallel crosses study, including the reciprocals, with turnip rape (Brassica rapa L.) was performed to determine both the magnitude of gene action and heterotic performance of the crosses for seed yield and important yield components. Field experiments were conducted at Uludag University, Bursa, Turkey, during the 2008-2009 and 2009-2010 growing seasons. All 20 F 1 hybrids and their parents were sown in a randomized complete block design with 3 replicates. During both years, the mean squares of the general combining ability (GCA), specific combining ability (SCA) and reciprocal combining ability (RCA) were statistically significant for all traits evaluated. The parent Malvira was a good general combiner because this parent had the highest significant positive GCA effects for all the characteristics evaluated. In addition, Lenox proved to be a good general combiner for plant height. The significant positive mid-parent and high-parent heterosis values were obtained with several crosses in important yield components. In conclusion, the parents used in this study exhibited positive GCA effects for seed yield. Therefore they could be considered as promising parents in the production of F 1 hybrids and in further breeding studies.

Research paper thumbnail of The Effect of Cilostazol on Right Heart Function and Pulmonary Pressure

Cardiovascular Therapeutics, Nov 27, 2013

Introduction: Cilostazol is a pde3 inhibitor and used to treat peripheral arterial disease. There... more Introduction: Cilostazol is a pde3 inhibitor and used to treat peripheral arterial disease. There are few reports on the influence of cilostazol on heart. Aims: The aim of this study was to assess this effect on right ventricular function and pulmonary artery pressure Methods: Forty patients with normal left and right ventricular ejection fraction and mild or moderate pulmonary artery hypertension were enrolled in the study. Right ventricular function was assessed by tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), tissue Doppler imaging (TDI) and two-dimensional speckle-tracking echocardiography (2D-STE) before and after oral administration of cilostazol. Also pulmonary artery pressure assessed before and after administration of cilostazol. Results: After cilostazol administration, there were significant increases in the TAPSE (1.9±0.3cm vs. 2.2±0.3cm, p<0.001). Peak longitudinal strain (-18.7±4.5% vs.-21.3 ±3.7 %, p=0.001), isovolumetric acceleration (IVA) (176.6±62.7 cm/sec 2 vs.200.6±61.9cm/sec 2 , p=0.025), right ventricular FAC increased significantly (37.6 ± 8.0% vs 41.5±8.9%, p<0.001). Pulmonary artery pressure decreased significantly (39.9±7.9 vs. 36.6±5.5mmHg, p=0.001) after cilostazol administration. Conclusion: Our study demonstrated that cilostazol improved right ventricular systolic function and reduced pulmonary artery pressure.

Research paper thumbnail of Left ventricular noncompaction in a patient with multiminicore disease

Journal of Cardiovascular Medicine, Oct 1, 2012

Although cardiac impairment secondary to respiratory involvement is not uncommonly observed in th... more Although cardiac impairment secondary to respiratory involvement is not uncommonly observed in the classic phenotype of multiminicore disease (MmD), primary cardiomyopathies have not been reported in the case of MmD. Left ventricular noncompaction is a cardiomyopathy ...

Research paper thumbnail of BNP levels in patients with long-term exposure to biomass fuel and its relation to right ventricular function

Pulmonary Pharmacology & Therapeutics, Oct 1, 2010

Previous studies have demonstrated a consistent increased risk for cardiovascular events and pulm... more Previous studies have demonstrated a consistent increased risk for cardiovascular events and pulmonary disease in patients with biomass fuel exposure (BFE). However right ventricular (RV) function have not been investigated yet in these patients. In this study, pulmonary function, right ventricular function and their relations with Brain Natriuretic Peptide (BNP) were investigated in non-smoking female patients with BFE. Methods: Our study population consisted of 39 female patients with BFE (group 1) and, 31 control subjects (group 2). Pulmonary function tests and transthoracic echocardiographic examination were performed. Right ventricular volumes, diameters and tissue velocities were obtained by tissue Doppler echocardiography. BNP levels were measured and correlated to right ventricular measurements and pulmonary artery pressure. Results: In BFE group, obstructive and restrictive spirometric findings were found. RV diameters, volumes and pulmonary artery pressure were higher in group 1 than group 2. BNP levels were well correlated with right ventricular end diastolic diameter and pulmonary artery pressure. A suspicion is also arised that toxic chemicals in biomass fuel may play a role in RV dysfunction. Conclusion: Biomass fuel exposure not only cause obstructive and/or restrictive lung disease but also leads to systolic and diastolic right ventricular dysfunction. BNP levels may be used to monitor pulmonary artery pressure and right ventricular enlargement in these patients.

Research paper thumbnail of The Effect Of Uncomplicated Percutaneus Coronary Intervention On Brachial Artery Flow Mediated Dilatation in Patients With Stable Angina Pectoris

İzmir tepecik eğitim hastanesi dergisi, 2008

Research paper thumbnail of Evaluation of Left Ventricular Function by Conventional Echocardiography and Tissue Doppler Imaging in Patients with Acute and Chronic Mitral Regurgitation

Journal of Medical Ultrasound, Dec 1, 2011

Open access under CC BY-NC-ND license. functions by TDI were also relatively preserved in patient... more Open access under CC BY-NC-ND license. functions by TDI were also relatively preserved in patients with acute MR when compared with those with chronic MR.

Research paper thumbnail of The Prognostic Value of Combined Fractional Flow Reserve and TIMI Frame Count Measurements in Patients with Stable Angina Pectoris and Acute Coronary Syndrome

Journal of Interventional Cardiology, Jul 8, 2010

Background: The aim of this study was to evaluate the prognostic value of different fractional fl... more Background: The aim of this study was to evaluate the prognostic value of different fractional flow reserve (FFR) cutoff values and corrected thrombolysis in myocardial infarction frame (TIMI) count (CTFC) measurements in a series of consecutive patients with moderate coronary lesions, including patients with unstable angina, myocardial infarction, and/or positive noninvasive functional test findings. Methods: We included 162 consecutive coronary patients in whom revascularization of a moderate coronary lesion was deferred based on a FFR value ≥0.75. Patients were divided according to the results of the intracoronary pressure and flow measurements into four groups: group A: 0.75

Research paper thumbnail of Uric Acid as a Marker of Oxidative Stress in Dilatation of the Ascending Aorta

American Journal of Hypertension, Feb 1, 2011

background Increased serum uric acid (Ua) has been shown to directly promote oxidative stress. Re... more background Increased serum uric acid (Ua) has been shown to directly promote oxidative stress. Recent studies point toward a role for oxidative stress in the pathogenesis of ascending aortic aneurysms (ascaas). This study was designed to examine the relationship between serum Ua concentrations, total antioxidant reductive capacity, and ascaas. Methods The serum Ua concentrations, total antioxidant reductive capacity were compared in 60 patients with ascending aortic dilatation (ectasia group (3.8-4.3 cm), 34 patients; aneurysmal group (≥4.4 cm), 26 patients) vs. 30 control subjects. The patients were evaluated by a complete transthoracic echocardiographic examination including measurement of the aortic dimensions. results The serum Ua concentration and total antioxidant reductive capacity were significantly higher in patients with ascaas. In multiple linear regression analysis, hypertension and serum Ua concentration were significantly associated with aortic dilatation (β = 0.3, P = 0.03; β = 0.15, P < 0.001, respectively). conclusions In conclusion, we found that serum Ua concentration and total antioxidant capacity (TaC) were significantly associated with aortic dilatation. The higher serum Ua concentration may be responsible for the elevated serum antioxidant capacity that was observed among individuals with ascaa. Large-scale epidemiological studies conducted over several years are required to correlate the crosssectional findings from this study with clinical outcome.

Research paper thumbnail of OP-014 the Effect of Cilostazol on Right Heart Function and Pulmonary Pressure

International Journal of Cardiology, Mar 1, 2013

Research paper thumbnail of Association Between Apolipoprotein-B100 and Apolipoprotein-A1 in Patients with Coronary Slow Flow

DergiPark (Istanbul University), Feb 1, 2009

Objective: Although several hypotheses have been suggested, the underlying mechanism of coronary ... more Objective: Although several hypotheses have been suggested, the underlying mechanism of coronary slow flow phenomenon (CSFP) has not been well established yet. The aim of this study was to determine the roles of plasma apolipoprotein-B100 (Apo-B) and apolipoprotein-A1 (Apo-A1) in CSFP which have an atherogenic effect and anti-atherogenic effects respectively. Methods: The study consisted of 31 patients with CSFP (group 1), 28 normal subjects as control group (group 2) and 30 patients with coronary artery disease (CAD) (group 3) detected by coronary angiography. CSFP was diagnosed by the TIMI frame count method. Blood Apo-B, Apo-A1, Apo-B/Apo-A1 ratio, and demographic parameters were compared between the groups. Results: The Apo-B values were 93±25 mg/dL, 90±26 mg/dL, and 106±27 mg/dL in groups 1, 2 and 3, respectively (p=0.048 between group 1 and 3, p=0.041 between group 2 and 3, p= NS between group 1 and 2). The Apo-A1values were 127±14 mg/dL, 125±21 mg/dL and 106±27 mg/dL in groups 1, 2 and 3 respectively (p=0.028 between group 1 and 3, p=0.021 between group 2 and 3, p= NS between group 1 and 2). The apo-B/apo-A1 ratio were 0.73±0.18, 0.69±0.23 and 0.98±0.20 in groups 1, 2 and 3 respectively (p=0.017 between group 1 and 3, p=0.010 between group 2 and 3, p= NS between group 1 and 2). Conclusion: Although lower levels of plasma Apo-A1 and higher levels of Apo-B and the ratio of Apo-B to Apo-A1 are related with CAD, there is no relationship between these apolipoproteins and CSFP.

Research paper thumbnail of Angiographic demonstration of percutaneous retrieval of an interatrial septal occluder device embolized into the right pulmonary artery

Türk kardiyoloji derneği arşivi, 2014

Research paper thumbnail of Aritmojenik Sa¤ Ventrikül Displazisi ile Birlikte Olan Biküspit Aort Kapak

Koşuyolu Heart Journal, 2010

Research paper thumbnail of Myocardial bridging as a cause of acute myocardial infarction: a case report-2

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002PMCID:PMC128836.Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Research paper thumbnail of Systolic compression at the mid-portion of LAD at the LAO view

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128836/Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Research paper thumbnail of ECG shows acute anteroseptal wall myocardial infarction

<b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute... more <b>Copyright information:</b>Taken from "Myocardial bridging as a cause of acute myocardial infarction: a case report"BMC Cardiovascular Disorders 2002;2():15-15.Published online 21 Sep 2002http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128836/Copyright © 2002 Akdemir et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.