Zelimir Kurtanjek - Academia.edu (original) (raw)
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Papers by Zelimir Kurtanjek
Biotechnology and Bioprocess Engineering, 2011
In this study, enzymatic oxidation of hexanol to hexanal (green note fragrance) using NAD+ depend... more In this study, enzymatic oxidation of hexanol to hexanal (green note fragrance) using NAD+ dependent commercial alcohol dehydrogenase from S. cerevisiae was conducted in continuously operated tubular microreactors with internal volumes of 6 and 13 μL and in a tubular microreactor with a volume of 2 μL that was equipped with internal micromixers. Flow profiles in microchannel were observed in experiments in which the aqueous phase was stained brilliant blue and the hexane was kept colourless. The effects of enzyme and coenzyme inlet concentrations and flow ratios of the immiscible phases on the conversion of hexanol and the volumetric productivity of hexanal were analyzed. Significant improvement in the conversion of hexanol when compared to the classical macroscale process was obtained for c i,hexanol = 5.5 mmol/L, c i,NAD+ = 0.55 mmol/L, and γ i,ADH = 0.092 g/L. In the 6 μL microreactor 11.78% conversion of hexanol was attained after 72 sec, while in the macroscale process 5.3% conversion of hexanol was reached after 180 sec.
Application of system theory in biology has led to development of computer languages for mathemat... more Application of system theory in biology has led to development of computer languages for mathematical modeling which are in open source and apply common standards for model trans-platform exchangeability and integration with extensive model banks, databases, numerical and statistical methods and graphical tools. Standardization has led to systems biology Markup language (SBML) based on XML format, while open source policy enables integration of computer resources and provides synergistic integration of scientific results and methodologies from various scientific fields. Different software projects have been initiated resulting in software such as: SB Toolbox, J Designer, SB Workbench (SBW), and Cell Designer. The main use of the systems biology software is to investigate biochemical networks, gene regulatory networks, signal transduction, cell communication, dynamical complex behavior, and most importantly to lead to understanding of life regulation. In this work is presented use of systems biology markup language and modeling tools applied for analysis of signal transduction in T-cell as apart of a human immune system.
Food Service Technology, 2004
Biotechnology and Bioprocess Engineering, 2011
In this study, enzymatic oxidation of hexanol to hexanal (green note fragrance) using NAD+ depend... more In this study, enzymatic oxidation of hexanol to hexanal (green note fragrance) using NAD+ dependent commercial alcohol dehydrogenase from S. cerevisiae was conducted in continuously operated tubular microreactors with internal volumes of 6 and 13 μL and in a tubular microreactor with a volume of 2 μL that was equipped with internal micromixers. Flow profiles in microchannel were observed in experiments in which the aqueous phase was stained brilliant blue and the hexane was kept colourless. The effects of enzyme and coenzyme inlet concentrations and flow ratios of the immiscible phases on the conversion of hexanol and the volumetric productivity of hexanal were analyzed. Significant improvement in the conversion of hexanol when compared to the classical macroscale process was obtained for c i,hexanol = 5.5 mmol/L, c i,NAD+ = 0.55 mmol/L, and γ i,ADH = 0.092 g/L. In the 6 μL microreactor 11.78% conversion of hexanol was attained after 72 sec, while in the macroscale process 5.3% conversion of hexanol was reached after 180 sec.
Application of system theory in biology has led to development of computer languages for mathemat... more Application of system theory in biology has led to development of computer languages for mathematical modeling which are in open source and apply common standards for model trans-platform exchangeability and integration with extensive model banks, databases, numerical and statistical methods and graphical tools. Standardization has led to systems biology Markup language (SBML) based on XML format, while open source policy enables integration of computer resources and provides synergistic integration of scientific results and methodologies from various scientific fields. Different software projects have been initiated resulting in software such as: SB Toolbox, J Designer, SB Workbench (SBW), and Cell Designer. The main use of the systems biology software is to investigate biochemical networks, gene regulatory networks, signal transduction, cell communication, dynamical complex behavior, and most importantly to lead to understanding of life regulation. In this work is presented use of systems biology markup language and modeling tools applied for analysis of signal transduction in T-cell as apart of a human immune system.
Food Service Technology, 2004