Zeridah Muyinda - Academia.edu (original) (raw)

Papers by Zeridah Muyinda

Journal of the American College of Radiology, Mar 1, 2024

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 1978

Pathogenese der Myositis ossificans bei neurologischen Syndromen. Net-venarzt43 (1972) 360-367 (1... more Pathogenese der Myositis ossificans bei neurologischen Syndromen. Net-venarzt43 (1972) 360-367 (16) Bekier, A., F. Gloor, R. Witzig: Differentialdiagnosnsche Schwierigkeiten hem einem Fall von aktiver Myositis ossificans nun traumatica in der Gravidität. Fortschr. Röntgenstr. 126 (1977) 43-47 Heruntergeladen von: NYU. Urheberrechtlich geschützt.

The Pan African medical journal, Jul 6, 2010

Background: Breast cancer is the third commonest cancer in Ugandan women. Women present late for ... more Background: Breast cancer is the third commonest cancer in Ugandan women. Women present late for breast cancer management which leads to high mortality rates. The objective of the study was to assess the knowledge, attitudes and practices of Ugandan women concerning breast cancer and mammography. Methods: This was a descriptive cross-sectional study where 100 women reporting to the Radiology department were interviewed. We used consecutive sampling. Interviewer-administered questionnaires were used to collect opinions of the participants. For data analysis, answers were described as knowledge, attitude, practice and they were correlated with control variables through the chi-square. Bivariate and logistic regression analyses were also used. Results: Most of the women (71%) had no idea about mammography. More than 50% did not know about risk factors for breast cancer. The attitude towards mammography was generally negative. Regarding seeking for mammography; level of literacy, occupation and marital status were significant on bivariate analysis, however only level of literacy and employment remained the significant independent variables on logistic regression analysis. The main barrier to mammography was mainly lack of information. Conclusion: Women in this study had Page number not for citation purposes 2 inadequate knowledge and inappropriate practice related to mammography as a procedure for breast cancer investigation.

Global journal of epidemiology and public health, Jun 15, 2022

Introduction: Cancer is still a world health concern. In developing countries like Uganda, cancer... more Introduction: Cancer is still a world health concern. In developing countries like Uganda, cancer is one of the major health problems that are increasing due to increased life expectancy and the pandemic of HIV/AIDS. Objective: To establish the incidence of different cancers among patients presenting at the Radiotherapy department of Mulago Hospital, Uganda. Methods: It was a retrospective study in which 2253 medical records of biopsy proven cancer patients who were accrued between January 2007 to December 2008 were retrieved and reviewed. Results: Of all cancers reported for females, cervical carcinoma was the most frequent seen with 43.6% of cases, followed by breast cancer seen in 21% of cases. Prostate cancer was the most frequent in males seen in 39.7% of cases. Conclusion: There is an increase in the number of cancer patients in Uganda. There has been a similar increase in mortality rates owing to the limited resources to curb the morbidity of the disease. Developing more radiotherapy centres to handle the increasing number of patients is highly recommended.

Journal of Health, Medicine and Nursing, 2015

The paper presents the assessment of radiation doses of staff in the Nuclear Medicine Unit of Mul... more The paper presents the assessment of radiation doses of staff in the Nuclear Medicine Unit of Mulago National Referral and Teaching Hospital. The doses received by staff are compared with the dose limits recommended by the International Atomic Energy Agency (IAEA), World Health Organization (WHO) and International Commission on Radiological Protection (ICRP). Doses of occupational workers in the Nuclear Medicine unit were monitored for a period of 5 months. Personal radiation doses were determined using two chip LiF TLD-100 dosimeter badges. The TLD badges and reader were calibrated using a standard 90-Strontium radiation source. The mean monthly effective radiation doses for the staff ranged from 0.78± 0.05mSv/month for nursing officers to 0.08± 0.05mSv/month for the nuclear medicine physician. These mean monthly effective radiation doses were projected to the annual effective radiation doses received by staff. The mean annual radiation doses were, 9.29±0.60mSv/yr for Nursing Officers, 2.79± 0.60mSv/yr for Medical Physicist and Radiographer, 6.46 ±0.60 mSv/yr for Radioimmunoassay Technologists, 1.71 ± 0.60 mSv/yr for Nuclear Medicine Technologist and 0.91±0.60 mSv/y for Nuclear Medicine Physician. The results of this study show that effective radiation doses received by the Nuclear Medicine staff of Mulago National Referral and Teaching Hospital are within the recommended dose limits for occupational workers.

AIDS research and therapy, Jan 25, 2018

Deep venous thrombosis (DVT) and its major complication pulmonary embolism (PE) are collectively ... more Deep venous thrombosis (DVT) and its major complication pulmonary embolism (PE) are collectively known as venous thromboembolism. In Uganda, the prevalence of DVT among HIV patients has not been previously published. The aim of the study was to determine the prevalence and sonographic features of lower limb deep venous thrombosis among HIV positive patients on anti-retroviral treatment (ART). This was a cross sectional study in which HIV positive patients on ART were recruited from an out-patient HIV clinic at Mulago National Referral Hospital. Patients were randomly selected and enrolled until a sample size of 384 was reached. Study participants underwent compression and Doppler ultrasound studies of both lower limb deep veins using Medison Sonoacer7 ultrasound machine. We found a prevalence of DVT of 9.1% (35 of 384 participants) among HIV patients on ART. The prevalence of latent (asymptomatic) DVT was 2.3%. Among 35 patients with DVT, 42.8% had chronic DVT; 31.1% had acute DVT a...

Dentomaxillofacial Radiology, 2010

The purpose of this study was to determine sonographically, in parotid glands of human immunodefi... more The purpose of this study was to determine sonographically, in parotid glands of human immunodeficiency virus-positive patients, the condition of glands with or without enlargement, and propose a classification system for the patterns observed using diagnostic ultrasound imaging. Methods: In this prospective clinical study, ultrasound scans were performed on 200 patients aged 4-62 years at Mulago Hospital, Uganda. Results: There were four main distinct ultrasound pathological patterns in the parotids, i.e. lymphocytic aggregations (LAs), lymphoepithelial cysts (LECs), fatty infiltration (FI) and lymphadenopathy only. There were additional subdivisions depending on the presence of echogenic foci and intraparotid lymphadenopathy. Of those patients (n 5 64) without parotid enlargement, only 8% showed normal ultrasound features, whereas 34% showed LECs and 31% showed LAs. Of those (n 5 136) with parotid enlargement, 46% showed LECs, 23% showed FI and 15% showed LAs. The overall prevalence of LECs in the study sample was 42%. LECs were multiple, mainly between 7 mm and 12 mm in diameter and 26% showed internal echogenic foci either mobile or stationary. In contrast, LAs tended to be ill-defined, less than 5 mm and were not associated with posterior acoustic enhancement. Features differentiating LAs from LECs have not been previously described. Parotid FI (lipodystrophy) was noted in patients on highly active antiretroviral therapy, who showed lesser prevalence of LECs after 12 months of treatment. Conclusions: Our study of 200 patients is probably the largest such study in the English language literature. The wide spectrum of diagnostic ultrasound patterns was categorized into four main groups (ten subgroups).

Journal of the Egyptian National Cancer Institute

Background In the Ugandan setting, investigation for PHNM with CT uses a protocol with both unenh... more Background In the Ugandan setting, investigation for PHNM with CT uses a protocol with both unenhanced and contrast enhanced procedures hence doubling the ionizing radiation exposure. The purpose of this study was to determine the feasibility of single CT procedures in diagnosing PHNM. Methods This was a cross-sectional study using CT images from patients, aged fifteen years and below, investigated for head and neck malignancies at the Uganda Cancer Institute. Three radiologists, observers A, B and C, with 12, 5 and 2 years of experience, respectively, participated in the study. They independently reported contrast enhanced images (protocol A), unenhanced images (protocol B), then both unenhanced and contrast enhanced images (protocol C) in 2 months intervals. Inter- and intra- observer agreement was determined using Gwen’s Agreement coefficient. Results Seventy-three CT scans of 36 boys and 37 girls, with a median age of 9 (3–13) years, were used. Intra-and inter-observer agreement...

Background Computed Tomographic (CT) scanning of the head can detect acute intracranial injury an... more Background Computed Tomographic (CT) scanning of the head can detect acute intracranial injury and help to identify patients requiring neurosurgical intervention. The inappropriate utilization of CT scan strains meagre imaging resources especially in resource-constrained settings and risks the patients to unnecessary radiation. The Canadian CT head rule (CCHR) is a validated clinical tool used to predict mild head injury patients that will have a clinically significant intracranial injury on head CT scan. This reduces the number of requested CT scans while at the same time ensuring that those who would benefit from it are easily identified. However, this tool has not been previously applied in many low income settings where it would be very useful. Objective To determine the appropriateness of head CT scans performed among patients with mild traumatic head injury based on the Canadian CT head rule (CCHR). Methods This was a cross sectional study conducted at the emergency department...

The Annals of African Surgery, 2012

Background: Mammography is an established screening tool for breast cancer in high-income countri... more Background: Mammography is an established screening tool for breast cancer in high-income countries but may not be feasible for most resource poor nations. Alternative modalities are needed to mitigate the impact of the increasing incidence and mortality due to breast cancer. This may require the development of new technologies or reevaluation of old technologies applicable to resource limited settings. Objective: To determine the sensitivity and specificity of breast transillumination as compared to mammography and to describe features of benign and malignant breast lesions as seen with breast transillumination. Methods: A single group descriptive analytical study was conducted over a six month period (2011) in the breast unit of Mulago National hospital. Eligible participants were consecutively sampled. Participants underwent Clinical Breast Examination (CBE), breast transillumination (BT), mammography (MG) and histopathological analysis of identified breast lumps. Sensitivity, specificity and predictive values were calculated. Features of the masses detected by transillumination were then described. Results: The number of participants recruited was 201 (mean age 42 years, range 30-80 years). The average palpable lump size was 3.8 cm (range 0.5 to 10 cm). BT had a sensitivity of 63.2% (PPV 86.8%) and a specificity of 89.5% (NPV 61.2%) with mammography as the reference standard. Also, 73.3% of breast lumps with irregular margins and 88.5% with dense opacity at transillumination turn out to be malignant at histopathology examination. Conclusion: The Breast transillumination technique had a moderate sensitivity of 63.2%. This warrants a large scale population-based evaluation of BT as a screening tool. This technique may not substitute mammography but to be considered an option where mammography access is limited.

East and Central African …

BackgroundThe increase in the prevalence of paediatric head and neck malignancies (PHNM) has led ... more BackgroundThe increase in the prevalence of paediatric head and neck malignancies (PHNM) has led to increased use of computerized tomography (CT), an ionizing radiation source. Children are at a risk of up to ten times more for radiation induced secondary malignancies. In the Ugandan setting, investigation for PHNM with CT uses a protocol with both unenhanced and contrast enhanced procedures hence doubling the ionizing radiation exposure. The purpose of this study was to determine the feasibility of single CT procedures in diagnosing PHNM.MethodsThis was a cross-sectional study using CT images from patients, aged fifteen years and below, investigated for head and neck malignancies at the Uganda Cancer Institute. Three radiologists; observer A, observer B and observer C, with 12, 5 and 2 years of experience, respectively, participated in the study. They independently reported contrast enhanced images (protocol A), unenhanced images (protocol B), then both unenhanced and contrast enha...

This data set represents the entire dataset for the ASK trial of Ugandan women without a diagnosi... more This data set represents the entire dataset for the ASK trial of Ugandan women without a diagnosis of breast cance

This was data used in our analysis of Ugandan women without a diagnosis of breast cancer

Most women with breast cancer in sub-Saharan Africa (SSA) are diagnosed with late-staged disease.... more Most women with breast cancer in sub-Saharan Africa (SSA) are diagnosed with late-staged disease. The current study assesses patient-related barriers among women from a general SSA population to better understand how patient-related barriers contribute to diagnostic delays. Using convenience-based sampling, 401 Ugandan women without breast cancer were surveyed to determine how prior participation in cancer detection practices correlate with patient-related barriers to prompt diagnosis. In a predominantly poor (76%) and rural population (75%), the median age of the participants was 38. Of the women surveyed, 155 (46%) had prior exposure to breast cancer education, 92 (27%) performed breast self-examination (BSE) and 68 (20%) had undergone a recent clinical breast examination (CBE), breast ultrasound or breast biopsy. The most commonly identified barriers to prompt diagnosis were knowledge deficits regarding early diagnosis (79%), economic barriers to accessing care (68%), fear (37%) and poor social support (24%). However, only women who reported knowledge deficits – a modifiable barrier – were less likely to participate in cancer detection practices (p<0.05). Women in urban and rural areas were similarly likely to report economic barriers, knowledge deficits and/or poor social support, but rural women were less likely than urban women to have received breast cancer education and/or perform BSE (p<0.001). Women who have had prior breast cancer education (p<0.001) and/or who perform BSE (p=0.02) were more likely to know where she can go to receive a diagnostic breast evaluation. These findings suggest that SSA countries developing early breast cancer detection programs should specifically address modifiable knowledge deficits among women less likely to achieve a diagnostic work-up to reduce diagnostic delays and improve breast cancer outcomes

Manson's Tropical Diseases, 2009

Background : The knee is prone to various pathology. Mulago Hospital records of 2001/2002 show th... more Background : The knee is prone to various pathology. Mulago Hospital records of 2001/2002 show that an average of 432 patients with knee joint disorders are seen in orthopaedic and rheumatology outpatient clinics out of a total of 5400 patients annually. For a long time the only mode of radiological investigation for these patients has been x-rays of the knee joints and this meant that limited information was got about the soft tissue component of the knee.Advances in technology with high frequency transducers, power Doppler ultrasound and extended field of view function have facilitated the progressive development of musculoskeletal sonography (MS). In developing countries like Uganda, where advanced imaging modalities like MRI are unaffordable and not readily available, ultrasound U/S serves as an efficient substitute in trained hands. This study was aimed at describing the sonographic pattern of knee joint pathology at Mulago Hospital in patients with knee joint symptoms. Methods...

Critical Care Research and Practice, 2016

Background. Critical care in Uganda is a neglected speciality and deemed costly with limited fund... more Background. Critical care in Uganda is a neglected speciality and deemed costly with limited funding/prioritization. We studied admission X-ray and MEWS as mortality predictors of ICU patients requiring mechanical ventilation. Materials and Methods. We did a cross-sectional study in Mulago Hospital ICU and 87 patients for mechanical ventilation were recruited with mortality as the outcome of interest. Chest X-ray results were the main independent variable and MEWS was also gotten for all patients. Results. We recruited 87 patients; most were males (60.92%), aged between 16 and 45 years (59.77%), and most admissions for mechanical ventilation were from the Trauma Unit (30.77%). Forty-one (47.13%) of the 87 patients died and of these 34 (53.13%) had an abnormal CXR with an insignificant IRR = 1.75 (0.90-3.38) (= 0.062). Patients with MEWS ≥ 5 (values = 0.018) and/or having an abnormal superior mediastinum (values = 0.013) showed a positive association with mortality while having a MEWS ≥ 5 had an incidence risk ratio = 3.29 (1.00-12.02) (= 0.018). MEWS was a good predictor of mortality (predictive value = 0.6739). Conclusion. Trauma (31%) caused most ICU admissions, having an abnormal admission chest X-rays positively associated with mortality and a high MEWS was also a good predictor of mortality.

East and Central African Journal of Surgery, 2010

Background: The Faculty of Medicine (FoM) has been training health professions in Uganda since 19... more Background: The Faculty of Medicine (FoM) has been training health professions in Uganda since 1924. Five years ago, it decided to change the undergraduate curriculum from traditional to Problem Based Learning (PBL) and adopted the SPICES model. Radiology was integrated into the different courses throughout the 5 year program. The objective was to improve the implementation of the integration of Radiology in the integrated PBL curriculum. Methods: This was a cross sectional descriptive study of radiologists and medical students using interviews and semi-structured questionnaires respectively. Results: Radiologists’ and students’ perceptions and opinions on Radiology training were gathered. A Radiology training rationale was developed. Learning outcomes for Radiology were defined and learning formats were chosen. Learning materials were identified and strategies to improve the implementation were formulated. Conclusions: This work has culminated into changes in Radiology integration ...